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The map label for this gene is gmuR [H]

Identifier: 116493505

GI number: 116493505

Start: 1752873

End: 1753586

Strand: Direct

Name: gmuR [H]

Synonym: PEPE_1777

Alternate gene names: 116493505

Gene position: 1752873-1753586 (Clockwise)

Preceding gene: 116493493

Following gene: 116493512

Centisome position: 95.66

GC content: 36.97

Gene sequence:

>714_bases
ATGTATAAATACGAAAAAATCTCGCAAGCGATTCGCAAACAAATTATTGAACAAAAAATTAAACCTGGAGCTTTACTGCC
GGATCAAAATCAATTAGCTAAAGAATTTAATACTACTCGTATAACGATTGGCAAAGCACTCCAATCCCTAATTATTGAAG
GGCTTATCTATAGCAAACGTGGTGCTGGGACGTTTGTTAGAAAAGATGCTCATTTGAATGACGAATTTACTAACGATGTT
GATAAACCTTTGGGGACTACCTCGACTCATCCGCATAGTAAAGTCACCAGTAAATATATTCATTTGACTGCTCGGATTGC
TAACGAAGTCGAAAAGAAAAATCTTCTACTAGAAGATGGTGAGACGGTCTACGTCATCAAACGGACGCGTTTTATCGAGG
GAAAAGCTTATAGTTATGAACAAACAATTATGCCAACTAAAATTGCAACAATAACCGAAGAAGTTTTAAAAAAATCTATT
TACCAATATCTAGAACATGAGTACCATTTAGAATTAGCTGGTTCCCATCGACAAATCACTGCCCGTAAAGTTTCTGAAGA
GGACGCTAAATTTCTGGGTGAAAAGTTGGGCGATCCAATCCTAGTGATTAGCCAAACTAGTTACTTAGTAGATGGAACCC
CTTTTGAATTTTCTGAATCTCGTTTTCCATACCGATCTAGCGCAGTATCTGCGGATGTCAATTTACTTGAATAA

Upstream 100 bases:

>100_bases
AATACTTTTATTTTAAAAGACTATACTTTTATAAAAATTGTGATTGTATTTAAGATACGCTAAAATGAGGGTAACGTCTT
AAAACGGAGTTTTAAACAAT

Downstream 100 bases:

>100_bases
AAAAAGCGTTCAGAAAAAATTTTCTGAACGCTTTTTTTATTTTTTAATTTTTAAAATAGATTCTGTATCCATTCGTTTAG
AAGTTATGCGGTTTACTTGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MYKYEKISQAIRKQIIEQKIKPGALLPDQNQLAKEFNTTRITIGKALQSLIIEGLIYSKRGAGTFVRKDAHLNDEFTNDV
DKPLGTTSTHPHSKVTSKYIHLTARIANEVEKKNLLLEDGETVYVIKRTRFIEGKAYSYEQTIMPTKIATITEEVLKKSI
YQYLEHEYHLELAGSHRQITARKVSEEDAKFLGEKLGDPILVISQTSYLVDGTPFEFSESRFPYRSSAVSADVNLLE

Sequences:

>Translated_237_residues
MYKYEKISQAIRKQIIEQKIKPGALLPDQNQLAKEFNTTRITIGKALQSLIIEGLIYSKRGAGTFVRKDAHLNDEFTNDV
DKPLGTTSTHPHSKVTSKYIHLTARIANEVEKKNLLLEDGETVYVIKRTRFIEGKAYSYEQTIMPTKIATITEEVLKKSI
YQYLEHEYHLELAGSHRQITARKVSEEDAKFLGEKLGDPILVISQTSYLVDGTPFEFSESRFPYRSSAVSADVNLLE
>Mature_237_residues
MYKYEKISQAIRKQIIEQKIKPGALLPDQNQLAKEFNTTRITIGKALQSLIIEGLIYSKRGAGTFVRKDAHLNDEFTNDV
DKPLGTTSTHPHSKVTSKYIHLTARIANEVEKKNLLLEDGETVYVIKRTRFIEGKAYSYEQTIMPTKIATITEEVLKKSI
YQYLEHEYHLELAGSHRQITARKVSEEDAKFLGEKLGDPILVISQTSYLVDGTPFEFSESRFPYRSSAVSADVNLLE

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=221, Percent_Identity=28.9592760180996, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790118, Length=220, Percent_Identity=28.6363636363636, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1788418, Length=221, Percent_Identity=25.3393665158371, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082252, Length=218, Percent_Identity=21.5596330275229, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26970; Mature: 26970

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKYEKISQAIRKQIIEQKIKPGALLPDQNQLAKEFNTTRITIGKALQSLIIEGLIYSKR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCC
GAGTFVRKDAHLNDEFTNDVDKPLGTTSTHPHSKVTSKYIHLTARIANEVEKKNLLLEDG
CCCCEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEECC
ETVYVIKRTRFIEGKAYSYEQTIMPTKIATITEEVLKKSIYQYLEHEYHLELAGSHRQIT
CEEEEEEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEH
ARKVSEEDAKFLGEKLGDPILVISQTSYLVDGTPFEFSESRFPYRSSAVSADVNLLE
HHHHCHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure
MYKYEKISQAIRKQIIEQKIKPGALLPDQNQLAKEFNTTRITIGKALQSLIIEGLIYSKR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCC
GAGTFVRKDAHLNDEFTNDVDKPLGTTSTHPHSKVTSKYIHLTARIANEVEKKNLLLEDG
CCCCEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEECC
ETVYVIKRTRFIEGKAYSYEQTIMPTKIATITEEVLKKSIYQYLEHEYHLELAGSHRQIT
CEEEEEEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEH
ARKVSEEDAKFLGEKLGDPILVISQTSYLVDGTPFEFSESRFPYRSSAVSADVNLLE
HHHHCHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]