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The map label for this gene is luxS

Identifier: 116493366

GI number: 116493366

Start: 1622129

End: 1622602

Strand: Reverse

Name: luxS

Synonym: PEPE_1638

Alternate gene names: 116493366

Gene position: 1622602-1622129 (Counterclockwise)

Preceding gene: 116493367

Following gene: 116493365

Centisome position: 88.55

GC content: 39.66

Gene sequence:

>474_bases
ATGGCAAAAGTAGAAAGCTTTGAATTGGATCACACAAAGGTAAAGGCTCCGTACGTACGTTTAATTACAGTTGAAACGGG
AAATAAGGGCGATAAGATTTCTAATTTCGATTTACGTTTAGTTCAACCAAACGAAAATGCGATTCCCACTGCAGGACTAC
ATACGATTGAACATTTGCTAGCTGGATTATTGCGAGATCGAATGGATGGAATTATCGACTGTTCTCCATTCGGATGTCGA
ACAGGTTTCCATTTGATTGCTTGGGGAGAACCTACAACCACAGAAGTTGCTAAAGCATTGAAGGGTGCACTAGAAGAAAT
CGCAAATGTTACTAAGTGGGAAGATGTACCAGGTACGGACATCTACAGTTGTGGTAATTACCGTGATCATTCACTATTTT
CAGCTAAAGAATGGGCGAAAAAGATTTTGGATGACGGTATCAGTGACCAACCTTTTGAACGAAATGTAATTTAA

Upstream 100 bases:

>100_bases
ACATTAGTCAGGACGATTTTTAAATGAATTTTTTAATTTATATCAGGATCGAGTTGGTCTAAAATAGGACATAGATACCG
ATGAATAGGGGGATGTTTTT

Downstream 100 bases:

>100_bases
TAAATTAAAAACCGAAACCGAATTAGAGTAGTTTGAATGCTGCTTTAATTCGGTTTTTTTGTACAACGGATAGATCATTA
ATTTTAGAAGTGACAATTGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MAKVESFELDHTKVKAPYVRLITVETGNKGDKISNFDLRLVQPNENAIPTAGLHTIEHLLAGLLRDRMDGIIDCSPFGCR
TGFHLIAWGEPTTTEVAKALKGALEEIANVTKWEDVPGTDIYSCGNYRDHSLFSAKEWAKKILDDGISDQPFERNVI

Sequences:

>Translated_157_residues
MAKVESFELDHTKVKAPYVRLITVETGNKGDKISNFDLRLVQPNENAIPTAGLHTIEHLLAGLLRDRMDGIIDCSPFGCR
TGFHLIAWGEPTTTEVAKALKGALEEIANVTKWEDVPGTDIYSCGNYRDHSLFSAKEWAKKILDDGISDQPFERNVI
>Mature_156_residues
AKVESFELDHTKVKAPYVRLITVETGNKGDKISNFDLRLVQPNENAIPTAGLHTIEHLLAGLLRDRMDGIIDCSPFGCRT
GFHLIAWGEPTTTEVAKALKGALEEIANVTKWEDVPGTDIYSCGNYRDHSLFSAKEWAKKILDDGISDQPFERNVI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=151, Percent_Identity=41.0596026490066, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_PEDPA (Q03DR3)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_805101.1
- ProteinModelPortal:   Q03DR3
- SMR:   Q03DR3
- STRING:   Q03DR3
- GeneID:   4417492
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1638
- NMPDR:   fig|278197.10.peg.1444
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- PhylomeDB:   Q03DR3
- ProtClustDB:   PRK02260
- BioCyc:   PPEN278197:PEPE_1638-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17469; Mature: 17338

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVESFELDHTKVKAPYVRLITVETGNKGDKISNFDLRLVQPNENAIPTAGLHTIEHLL
CCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
AGLLRDRMDGIIDCSPFGCRTGFHLIAWGEPTTTEVAKALKGALEEIANVTKWEDVPGTD
HHHHHHHHCCEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IYSCGNYRDHSLFSAKEWAKKILDDGISDQPFERNVI
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AKVESFELDHTKVKAPYVRLITVETGNKGDKISNFDLRLVQPNENAIPTAGLHTIEHLL
CCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
AGLLRDRMDGIIDCSPFGCRTGFHLIAWGEPTTTEVAKALKGALEEIANVTKWEDVPGTD
HHHHHHHHCCEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IYSCGNYRDHSLFSAKEWAKKILDDGISDQPFERNVI
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA