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The map label for this gene is arcB

Identifier: 116493359

GI number: 116493359

Start: 1614124

End: 1615125

Strand: Reverse

Name: arcB

Synonym: PEPE_1631

Alternate gene names: 116493359

Gene position: 1615125-1614124 (Counterclockwise)

Preceding gene: 116493361

Following gene: 116493358

Centisome position: 88.14

GC content: 37.72

Gene sequence:

>1002_bases
ATGTCATTTAACTTACGTAACCGCAGTTTTTTAACCTTATCAGATTTTAGTACTCGTGAAATGGAATACATGCTTAATTT
AGCTGAGGATTTAAAGAAAGCTAAATATGCTGGCTATGAAGGTAATCGCTTGGCTGGCAAGAATATCGCTTTGATTTTTG
AAAAAGATTCAACTCGAACACGTTGTGCTTTTGAAGTTGGTGCTAAAGATGAAGGTGCTCACGTAACTTATCTTGGTCCT
TCAGGCTCACACATTGGCTACAAAGAATCAGTTAAAGATACAGCTCGTGTCTTGGGTGGTATGTTTGATGGGATTGAATA
TCGTGGATTCTCACAACGCTCAGCAGAAACGTTAGCTGAATATTCAGGTGTTCCTGTATGGAATGGTCTAACTGATGAAG
ATCACCCAACTCAAGTTTTAGCTGATTTCCTAACGGCTAAGGAAGTTTTGAAGAAAGAATATAAAGATATTAAATTTGCT
TTTGTTGGAGACGGTCAAGACAACGTATCTAATGCTTTGATGCTAGGTGCTGCTGTAATGGGAATGGAATATCACGTTGT
AACCCCTAAAGAACTTGAACCAACCAAGGACGTCTTAGACAAAGCTAACGCAATTGCTGCTAAAACAGGCGGTAAAATCG
TTGTTGAAAATGACGTTAAAGCTGGTGTTAAGAATATGGATGTTATCTATACCGATGTATGGGTATCAATGGGTGAACCA
GATGAAATGTGGCAAAAGCGTATTAAATTATTGAAGCCATATCAAGTAACTAAAGAAGTGATGGAAGCTACCGAAAATCC
AAATGCAATCTTTGAACACTGTCTGCCTGCATTCCACAATACAGACACATCAATTGGTAAAAAGATTGAAGAAAAATATG
GTCTATCTGAAATGGAAGTTACTGATGAAGTCTTTGAAAGTAGTCAATCAGTTGTATTCCAAGAAGCTGAAAATCGGATG
CACACAATTAAAGCTGTCATGGTTGCAACTTTAGGTGACTAA

Upstream 100 bases:

>100_bases
AAATAATATTAATTTTTAAGAAAATCAATTGATCACTGAAGCTTTGTGAAAGCGCTTGCTAGAATTAAACACGTAATCAA
ATATAGAGGAGGACGTTAAA

Downstream 100 bases:

>100_bases
GGAGGGCGAGTTTATGTCAAAAATGGTGGTTGCCTTAGGTGGTAATGCTTTAGGAAAGAGCCCTGAGGAACAGTTACAGT
TAGTGAAAAATACGGCTGCA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSFNLRNRSFLTLSDFSTREMEYMLNLAEDLKKAKYAGYEGNRLAGKNIALIFEKDSTRTRCAFEVGAKDEGAHVTYLGP
SGSHIGYKESVKDTARVLGGMFDGIEYRGFSQRSAETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYKDIKFA
FVGDGQDNVSNALMLGAAVMGMEYHVVTPKELEPTKDVLDKANAIAAKTGGKIVVENDVKAGVKNMDVIYTDVWVSMGEP
DEMWQKRIKLLKPYQVTKEVMEATENPNAIFEHCLPAFHNTDTSIGKKIEEKYGLSEMEVTDEVFESSQSVVFQEAENRM
HTIKAVMVATLGD

Sequences:

>Translated_333_residues
MSFNLRNRSFLTLSDFSTREMEYMLNLAEDLKKAKYAGYEGNRLAGKNIALIFEKDSTRTRCAFEVGAKDEGAHVTYLGP
SGSHIGYKESVKDTARVLGGMFDGIEYRGFSQRSAETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYKDIKFA
FVGDGQDNVSNALMLGAAVMGMEYHVVTPKELEPTKDVLDKANAIAAKTGGKIVVENDVKAGVKNMDVIYTDVWVSMGEP
DEMWQKRIKLLKPYQVTKEVMEATENPNAIFEHCLPAFHNTDTSIGKKIEEKYGLSEMEVTDEVFESSQSVVFQEAENRM
HTIKAVMVATLGD
>Mature_332_residues
SFNLRNRSFLTLSDFSTREMEYMLNLAEDLKKAKYAGYEGNRLAGKNIALIFEKDSTRTRCAFEVGAKDEGAHVTYLGPS
GSHIGYKESVKDTARVLGGMFDGIEYRGFSQRSAETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYKDIKFAF
VGDGQDNVSNALMLGAAVMGMEYHVVTPKELEPTKDVLDKANAIAAKTGGKIVVENDVKAGVKNMDVIYTDVWVSMGEPD
EMWQKRIKLLKPYQVTKEVMEATENPNAIFEHCLPAFHNTDTSIGKKIEEKYGLSEMEVTDEVFESSQSVVFQEAENRMH
TIKAVMVATLGD

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=331, Percent_Identity=39.2749244712991, Blast_Score=215, Evalue=5e-56,
Organism=Escherichia coli, GI1786469, Length=332, Percent_Identity=55.7228915662651, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1790703, Length=327, Percent_Identity=56.2691131498471, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI2367364, Length=209, Percent_Identity=30.1435406698565, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322373, Length=328, Percent_Identity=30.7926829268293, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322331, Length=163, Percent_Identity=29.4478527607362, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OTC_PEDPA (Q03DS0)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_805094.1
- ProteinModelPortal:   Q03DS0
- SMR:   Q03DS0
- STRING:   Q03DS0
- GeneID:   4417485
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1631
- NMPDR:   fig|278197.10.peg.1437
- eggNOG:   COG0078
- HOGENOM:   HBG579429
- OMA:   DFRIFAP
- PhylomeDB:   Q03DS0
- ProtClustDB:   PRK04284
- BioCyc:   PPEN278197:PEPE_1631-MONOMER
- HAMAP:   MF_01109
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292
- PRINTS:   PR00100
- PRINTS:   PR00102
- TIGRFAMs:   TIGR00658

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: =2.1.3.3

Molecular weight: Translated: 37105; Mature: 36974

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: BINDING 108-108 BINDING 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNLRNRSFLTLSDFSTREMEYMLNLAEDLKKAKYAGYEGNRLAGKNIALIFEKDSTRT
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEECCCCCC
RCAFEVGAKDEGAHVTYLGPSGSHIGYKESVKDTARVLGGMFDGIEYRGFSQRSAETLAE
EEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYKDIKFAFVGDGQDNVSNALMLGAAVM
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHH
GMEYHVVTPKELEPTKDVLDKANAIAAKTGGKIVVENDVKAGVKNMDVIYTDVWVSMGEP
CCEEEEECCCCCCCHHHHHHHHHHEEECCCCEEEEECCHHCCCCCCEEEEEEEEEECCCH
DEMWQKRIKLLKPYQVTKEVMEATENPNAIFEHCLPAFHNTDTSIGKKIEEKYGLSEMEV
HHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHH
TDEVFESSQSVVFQEAENRMHTIKAVMVATLGD
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFNLRNRSFLTLSDFSTREMEYMLNLAEDLKKAKYAGYEGNRLAGKNIALIFEKDSTRT
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEECCCCCC
RCAFEVGAKDEGAHVTYLGPSGSHIGYKESVKDTARVLGGMFDGIEYRGFSQRSAETLAE
EEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYKDIKFAFVGDGQDNVSNALMLGAAVM
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHH
GMEYHVVTPKELEPTKDVLDKANAIAAKTGGKIVVENDVKAGVKNMDVIYTDVWVSMGEP
CCEEEEECCCCCCCHHHHHHHHHHEEECCCCEEEEECCHHCCCCCCEEEEEEEEEECCCH
DEMWQKRIKLLKPYQVTKEVMEATENPNAIFEHCLPAFHNTDTSIGKKIEEKYGLSEMEV
HHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHH
TDEVFESSQSVVFQEAENRMHTIKAVMVATLGD
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA