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The map label for this gene is dtpT [H]

Identifier: 116493269

GI number: 116493269

Start: 1501096

End: 1502562

Strand: Reverse

Name: dtpT [H]

Synonym: PEPE_1534

Alternate gene names: 116493269

Gene position: 1502562-1501096 (Counterclockwise)

Preceding gene: 116493270

Following gene: 116493268

Centisome position: 82.0

GC content: 36.61

Gene sequence:

>1467_bases
TTGAATACACAAGATAAGGATACAGCATTTCTTGGTCAACCACGTGGATTAATGACGTTGTTCTTCACGGAAATGTGGGA
ACGTTTCAGTTACTACGGTATGCGTGCAATTTTAATTTATTACATGTATTACGCTGTAACCAAGGGTGGTTTAGGCTTTA
GTCAAGCCACTGCTGCTTCAGTAATGGCCATTTATGGTTCACTGGTTTATCTAGCTAGTGTTGCTGGTGGGTTTATCAGT
GACCGAATTTTAGGTAGTCGAAAAACCGTATTTTACGGTGGTGTATTGATCATGTTTGGTCATATTGCACTTTCACTTCC
TTTCGGTGGGGCGGCCCTACTAGTATCAATTGCTTTAATTGTTGCTGGTACTGGTATGTTAAAACCAAATGTTTCTGAAA
TGGTTGGATCACTATATTCCGTGGAGGATACGAGACGTGATGCCGGATTTAGTATTTTTGTTTTCGGTATTAATCTAGGT
GCTTTATTAGCTCCCATAATTGTTTCGTGGGTTGGTTTTAATATGAGTTTCCATGCTGGATTCTCATTAGCTGCAATTGG
TATGTTCTTTGGATTAGTCCAATATTATATTGATGGTAAAAAATATTTAAATAAAGATAGTTTATATCCATCAGATCCAA
TTCAACCCGATGAAGTCAAAAAATTTAGTCTTCGAGTTTTAATGGGTGTGATTGTATTAGCATTAATTTTAGTGGTTATG
TTTGTTGCTAATGCATTAACAATTGATAATGTTGTTCTATTAATTAGTATTATTGCTGTTATTGCTCCAATTGTTTACTT
TATCATCATGTTTTCAAGTAGTAAGGTTTCTAAAACAGAACGTTCACGTTTATGGGCTTATGTGCCATTATTTATCGCTG
CAACGTTATTCTGGGCAATTGAAGAACAAGGTTCAGTTGTTTTAGCATTATTTGCTGCTGATCGTACTCAATTAAACTAC
GGTTGGATGCATATTACGCCCGCTAACTTCCAGTCCCTTAATCCATTATTCATCATGCTTTATACACCAATTTTTGCATG
GCTATGGACTAAGTTAGGTAAGAAGCAACCTTCATCACCTAAGAAATTTACGTATGGACTTGTATTTACGGGTCTATCAT
ACTTATTTATTGCTTTACCTGGTTTGATGTTTGGTACTGATGGTAAGGTTAATGCTCTTTGGTTAGTTGGTAGCTGGGCA
ATTGTTGAAATTGGTGAAATGTTAATCTCACCAATTGGTTTATCTGTAACAACCAAATTGGCACCTGCTGCATTTGCTTC
TCAAATGATGAGTATGTGGTTCTTAGCCGATGCTGCTGGACAAGCAATTAACGCTCAGTTAGTTCGCTTCTACCCAGGAC
ATGAAGTAGCTTACTTTATTGTATTAGGTCTTGTAACACTAGTCTTTGCACTCGTACTATTAATTTGTTCACCATGGATT
ACTAAGAAGATGCAAGGGATTAGATAA

Upstream 100 bases:

>100_bases
AGCCGGCATTTGTTTGGATGCGCCTTAATGTTAAGTTAAGGCGCATTTTTTCATATACAGTCTTTGTTTTTAAGGCGAAA
ATTATGGAGGAAATATACAA

Downstream 100 bases:

>100_bases
TTAAATATTTGAATTCAAGAGATGAACTAGGTTATGCTTAGTTCATCTTTTTATTTTGGAGGGATTTATGGCTAGAAAAG
TAATACTTTTTATTGCAATG

Product: dipeptide/tripeptide permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNTQDKDTAFLGQPRGLMTLFFTEMWERFSYYGMRAILIYYMYYAVTKGGLGFSQATAASVMAIYGSLVYLASVAGGFIS
DRILGSRKTVFYGGVLIMFGHIALSLPFGGAALLVSIALIVAGTGMLKPNVSEMVGSLYSVEDTRRDAGFSIFVFGINLG
ALLAPIIVSWVGFNMSFHAGFSLAAIGMFFGLVQYYIDGKKYLNKDSLYPSDPIQPDEVKKFSLRVLMGVIVLALILVVM
FVANALTIDNVVLLISIIAVIAPIVYFIIMFSSSKVSKTERSRLWAYVPLFIAATLFWAIEEQGSVVLALFAADRTQLNY
GWMHITPANFQSLNPLFIMLYTPIFAWLWTKLGKKQPSSPKKFTYGLVFTGLSYLFIALPGLMFGTDGKVNALWLVGSWA
IVEIGEMLISPIGLSVTTKLAPAAFASQMMSMWFLADAAGQAINAQLVRFYPGHEVAYFIVLGLVTLVFALVLLICSPWI
TKKMQGIR

Sequences:

>Translated_488_residues
MNTQDKDTAFLGQPRGLMTLFFTEMWERFSYYGMRAILIYYMYYAVTKGGLGFSQATAASVMAIYGSLVYLASVAGGFIS
DRILGSRKTVFYGGVLIMFGHIALSLPFGGAALLVSIALIVAGTGMLKPNVSEMVGSLYSVEDTRRDAGFSIFVFGINLG
ALLAPIIVSWVGFNMSFHAGFSLAAIGMFFGLVQYYIDGKKYLNKDSLYPSDPIQPDEVKKFSLRVLMGVIVLALILVVM
FVANALTIDNVVLLISIIAVIAPIVYFIIMFSSSKVSKTERSRLWAYVPLFIAATLFWAIEEQGSVVLALFAADRTQLNY
GWMHITPANFQSLNPLFIMLYTPIFAWLWTKLGKKQPSSPKKFTYGLVFTGLSYLFIALPGLMFGTDGKVNALWLVGSWA
IVEIGEMLISPIGLSVTTKLAPAAFASQMMSMWFLADAAGQAINAQLVRFYPGHEVAYFIVLGLVTLVFALVLLICSPWI
TKKMQGIR
>Mature_488_residues
MNTQDKDTAFLGQPRGLMTLFFTEMWERFSYYGMRAILIYYMYYAVTKGGLGFSQATAASVMAIYGSLVYLASVAGGFIS
DRILGSRKTVFYGGVLIMFGHIALSLPFGGAALLVSIALIVAGTGMLKPNVSEMVGSLYSVEDTRRDAGFSIFVFGINLG
ALLAPIIVSWVGFNMSFHAGFSLAAIGMFFGLVQYYIDGKKYLNKDSLYPSDPIQPDEVKKFSLRVLMGVIVLALILVVM
FVANALTIDNVVLLISIIAVIAPIVYFIIMFSSSKVSKTERSRLWAYVPLFIAATLFWAIEEQGSVVLALFAADRTQLNY
GWMHITPANFQSLNPLFIMLYTPIFAWLWTKLGKKQPSSPKKFTYGLVFTGLSYLFIALPGLMFGTDGKVNALWLVGSWA
IVEIGEMLISPIGLSVTTKLAPAAFASQMMSMWFLADAAGQAINAQLVRFYPGHEVAYFIVLGLVTLVFALVLLICSPWI
TKKMQGIR

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=166, Percent_Identity=32.5301204819277, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4827008, Length=182, Percent_Identity=31.3186813186813, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789911, Length=503, Percent_Identity=28.6282306163022, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1790572, Length=414, Percent_Identity=30.1932367149758, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787922, Length=488, Percent_Identity=25.2049180327869, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786927, Length=419, Percent_Identity=29.1169451073986, Blast_Score=155, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71987453, Length=384, Percent_Identity=25.5208333333333, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569141, Length=354, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639585, Length=369, Percent_Identity=27.9132791327913, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24639583, Length=369, Percent_Identity=27.9132791327913, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24639581, Length=369, Percent_Identity=27.9132791327913, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571102, Length=161, Percent_Identity=36.6459627329193, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571100, Length=161, Percent_Identity=36.6459627329193, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571098, Length=165, Percent_Identity=35.7575757575758, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53645; Mature: 53645

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQDKDTAFLGQPRGLMTLFFTEMWERFSYYGMRAILIYYMYYAVTKGGLGFSQATAAS
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VMAIYGSLVYLASVAGGFISDRILGSRKTVFYGGVLIMFGHIALSLPFGGAALLVSIALI
HHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VAGTGMLKPNVSEMVGSLYSVEDTRRDAGFSIFVFGINLGALLAPIIVSWVGFNMSFHAG
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEECCC
FSLAAIGMFFGLVQYYIDGKKYLNKDSLYPSDPIQPDEVKKFSLRVLMGVIVLALILVVM
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVANALTIDNVVLLISIIAVIAPIVYFIIMFSSSKVSKTERSRLWAYVPLFIAATLFWAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EEQGSVVLALFAADRTQLNYGWMHITPANFQSLNPLFIMLYTPIFAWLWTKLGKKQPSSP
HCCCCEEEEEEECCCCEEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
KKFTYGLVFTGLSYLFIALPGLMFGTDGKVNALWLVGSWAIVEIGEMLISPIGLSVTTKL
CCEEHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHH
APAAFASQMMSMWFLADAAGQAINAQLVRFYPGHEVAYFIVLGLVTLVFALVLLICSPWI
HHHHHHHHHHHHHHHHHHHCCHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
TKKMQGIR
HHHHCCCC
>Mature Secondary Structure
MNTQDKDTAFLGQPRGLMTLFFTEMWERFSYYGMRAILIYYMYYAVTKGGLGFSQATAAS
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VMAIYGSLVYLASVAGGFISDRILGSRKTVFYGGVLIMFGHIALSLPFGGAALLVSIALI
HHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VAGTGMLKPNVSEMVGSLYSVEDTRRDAGFSIFVFGINLGALLAPIIVSWVGFNMSFHAG
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEECCC
FSLAAIGMFFGLVQYYIDGKKYLNKDSLYPSDPIQPDEVKKFSLRVLMGVIVLALILVVM
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVANALTIDNVVLLISIIAVIAPIVYFIIMFSSSKVSKTERSRLWAYVPLFIAATLFWAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EEQGSVVLALFAADRTQLNYGWMHITPANFQSLNPLFIMLYTPIFAWLWTKLGKKQPSSP
HCCCCEEEEEEECCCCEEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
KKFTYGLVFTGLSYLFIALPGLMFGTDGKVNALWLVGSWAIVEIGEMLISPIGLSVTTKL
CCEEHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHH
APAAFASQMMSMWFLADAAGQAINAQLVRFYPGHEVAYFIVLGLVTLVFALVLLICSPWI
HHHHHHHHHHHHHHHHHHHCCHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
TKKMQGIR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]