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The map label for this gene is nagA [H]

Identifier: 116493265

GI number: 116493265

Start: 1497211

End: 1498353

Strand: Reverse

Name: nagA [H]

Synonym: PEPE_1528

Alternate gene names: 116493265

Gene position: 1498353-1497211 (Counterclockwise)

Preceding gene: 116493266

Following gene: 116493264

Centisome position: 81.77

GC content: 39.02

Gene sequence:

>1143_bases
ATGAGTACAGTTTTGCGTCATGCTACTATTTATACTGGTTTAGAAAAAATTGAAGATGGTTACATTCGATTTGGTAAAAA
AATTGAAGCCGTTGGTCCAATGAGCGAATACAAAGCCCAAGGTGATGATCAAGTTTTCTATGCTGGAGAAAAGATTATTG
TTCCAGGATTCATTGATGTACATACACACGGTGGATACGGATTTGATGCCATGGATGGTGATCCAGATCAAATCAATGAA
ATGGTAAATAAAGCCGTTGTTAACGAAGGGGTTACCAGCTTCTTTTGTACAACAATGACCCAATCAAATGCCAACATTGA
AAAAGCAATGCGTGGGGTTGCGAAAGCTGCTGAAGATAACCCAGTTATCCAAGGGGTTCATTTGGAAGGACCATTTATTT
CTACTAAGTATAAGGGTGCTCAACCTGAAGAGTACATCAAGGATCCAGATGCAGAACTTTTGGGTAAATGGAATGAATTA
TCTGGTGGTCGTGTTAAGTTGATTACAATTGCACCTGAACATAAGGGATCTGATGCTTTTGAAGCTTACTGTTTAGACCA
TGGAATTGTGCCTTCAGTGGGTCATTCAGACGCAACTCGTGCGGAACTACTAAATAGTACTGTTACTCATGCAACTCATC
TTTACAATGCTCAACGTGAGTTTAAGCATCGCGAACCAGGTGTAACTGGACACGTTATGTTAGAAGACAACATTTACGCT
GAATTAATTTGTGATGGCTTCCATATCGTTCCTGATATGCTTAAATTAGCATACGAAGTTAAGGGACCAGAACGAATTGA
CCTAGTTACAGATTCAATGCGGGCTAAAGGATTTGCTGAAGGTGAAAGTGAACTTGGTGGACAAAAAGTTTACGTTAAAG
ACAAACAAGCACGTTTGGAAGATGGTACATTAGCTGGTTCTGTACTTGCATTTGATGATGCATTTAGAAATGCAATGCGT
TTCTTTAATTGCGGAATTGCTGAAGCTGTACAAATGAGCTCAGTTAACCAAGCTCGCGAATTTGGTTTGGATTCAAAGGG
AACACTTGAAGTTGGTAAGGATGCAGATATCAACGTCTTTGATAGCAACCTTAACAAATTGGAAACATATAGTTACGGGA
AAAAGTTTTCTAAAGAAGACTAA

Upstream 100 bases:

>100_bases
TCGATGCTACGGTAGCAAAAGAAATCAATCATTAGAATCTTGTTTTTTGGTCTATACCGATATATAATGGATTTAGATTA
AAAATTTAGGAGGAAAATTC

Downstream 100 bases:

>100_bases
TAGTCAAACATTATAGGGGTACAAGAATGAATTCACCGGTATATATTCAAATTCATAATGAAATCAAAAAGGCGATTGAA
GCCGGGAAATGGAAAGTGGG

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSTVLRHATIYTGLEKIEDGYIRFGKKIEAVGPMSEYKAQGDDQVFYAGEKIIVPGFIDVHTHGGYGFDAMDGDPDQINE
MVNKAVVNEGVTSFFCTTMTQSNANIEKAMRGVAKAAEDNPVIQGVHLEGPFISTKYKGAQPEEYIKDPDAELLGKWNEL
SGGRVKLITIAPEHKGSDAFEAYCLDHGIVPSVGHSDATRAELLNSTVTHATHLYNAQREFKHREPGVTGHVMLEDNIYA
ELICDGFHIVPDMLKLAYEVKGPERIDLVTDSMRAKGFAEGESELGGQKVYVKDKQARLEDGTLAGSVLAFDDAFRNAMR
FFNCGIAEAVQMSSVNQAREFGLDSKGTLEVGKDADINVFDSNLNKLETYSYGKKFSKED

Sequences:

>Translated_380_residues
MSTVLRHATIYTGLEKIEDGYIRFGKKIEAVGPMSEYKAQGDDQVFYAGEKIIVPGFIDVHTHGGYGFDAMDGDPDQINE
MVNKAVVNEGVTSFFCTTMTQSNANIEKAMRGVAKAAEDNPVIQGVHLEGPFISTKYKGAQPEEYIKDPDAELLGKWNEL
SGGRVKLITIAPEHKGSDAFEAYCLDHGIVPSVGHSDATRAELLNSTVTHATHLYNAQREFKHREPGVTGHVMLEDNIYA
ELICDGFHIVPDMLKLAYEVKGPERIDLVTDSMRAKGFAEGESELGGQKVYVKDKQARLEDGTLAGSVLAFDDAFRNAMR
FFNCGIAEAVQMSSVNQAREFGLDSKGTLEVGKDADINVFDSNLNKLETYSYGKKFSKED
>Mature_379_residues
STVLRHATIYTGLEKIEDGYIRFGKKIEAVGPMSEYKAQGDDQVFYAGEKIIVPGFIDVHTHGGYGFDAMDGDPDQINEM
VNKAVVNEGVTSFFCTTMTQSNANIEKAMRGVAKAAEDNPVIQGVHLEGPFISTKYKGAQPEEYIKDPDAELLGKWNELS
GGRVKLITIAPEHKGSDAFEAYCLDHGIVPSVGHSDATRAELLNSTVTHATHLYNAQREFKHREPGVTGHVMLEDNIYAE
LICDGFHIVPDMLKLAYEVKGPERIDLVTDSMRAKGFAEGESELGGQKVYVKDKQARLEDGTLAGSVLAFDDAFRNAMRF
FNCGIAEAVQMSSVNQAREFGLDSKGTLEVGKDADINVFDSNLNKLETYSYGKKFSKED

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=413, Percent_Identity=30.2663438256659, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI224922791, Length=410, Percent_Identity=30.2439024390244, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1786892, Length=382, Percent_Identity=29.8429319371728, Blast_Score=152, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17553768, Length=383, Percent_Identity=31.8537859007833, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI19920392, Length=342, Percent_Identity=32.7485380116959, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281361140, Length=355, Percent_Identity=31.5492957746479, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41785; Mature: 41654

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLRHATIYTGLEKIEDGYIRFGKKIEAVGPMSEYKAQGDDQVFYAGEKIIVPGFIDV
CCCHHHHHHHHHHHHHHHCHHHHHCCEEECCCCHHHHHCCCCCEEEEECCEEEECCEEEE
HTHGGYGFDAMDGDPDQINEMVNKAVVNEGVTSFFCTTMTQSNANIEKAMRGVAKAAEDN
ECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHEEHHHCCCCCCHHHHHHHHHHHCCCC
PVIQGVHLEGPFISTKYKGAQPEEYIKDPDAELLGKWNELSGGRVKLITIAPEHKGSDAF
CCEEEEEECCCEEECCCCCCCCHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCHH
EAYCLDHGIVPSVGHSDATRAELLNSTVTHATHLYNAQREFKHREPGVTGHVMLEDNIYA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEE
ELICDGFHIVPDMLKLAYEVKGPERIDLVTDSMRAKGFAEGESELGGQKVYVKDKQARLE
EEHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCHHHCCCCEEEEECCHHCCC
DGTLAGSVLAFDDAFRNAMRFFNCGIAEAVQMSSVNQAREFGLDSKGTLEVGKDADINVF
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEE
DSNLNKLETYSYGKKFSKED
CCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STVLRHATIYTGLEKIEDGYIRFGKKIEAVGPMSEYKAQGDDQVFYAGEKIIVPGFIDV
CCHHHHHHHHHHHHHHHCHHHHHCCEEECCCCHHHHHCCCCCEEEEECCEEEECCEEEE
HTHGGYGFDAMDGDPDQINEMVNKAVVNEGVTSFFCTTMTQSNANIEKAMRGVAKAAEDN
ECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHEEHHHCCCCCCHHHHHHHHHHHCCCC
PVIQGVHLEGPFISTKYKGAQPEEYIKDPDAELLGKWNELSGGRVKLITIAPEHKGSDAF
CCEEEEEECCCEEECCCCCCCCHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCHH
EAYCLDHGIVPSVGHSDATRAELLNSTVTHATHLYNAQREFKHREPGVTGHVMLEDNIYA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEE
ELICDGFHIVPDMLKLAYEVKGPERIDLVTDSMRAKGFAEGESELGGQKVYVKDKQARLE
EEHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCHHHCCCCEEEEECCHHCCC
DGTLAGSVLAFDDAFRNAMRFFNCGIAEAVQMSSVNQAREFGLDSKGTLEVGKDADINVF
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEE
DSNLNKLETYSYGKKFSKED
CCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]