Click here to switch to the map view.

The map label for this gene is atpD

Identifier: 116493065

GI number: 116493065

Start: 1305858

End: 1307267

Strand: Reverse

Name: atpD

Synonym: PEPE_1317

Alternate gene names: 116493065

Gene position: 1307267-1305858 (Counterclockwise)

Preceding gene: 116493066

Following gene: 116493064

Centisome position: 71.34

GC content: 41.13

Gene sequence:

>1410_bases
ATGAGTACTGGTAAAGTTGTTCAAGTTATCGGACCAGTTATCGACGTTGAATTTCCCCTTGACGAAGAATTACCAACTAT
CAATAACGCTTTGAAGATTAAAAAGGCGGATGGTACTGTCCTAGTTTCTGAAGTAACGCTTGAATTAGGTGATGGTGTTG
TAAGAACCATCGCTATGGATGGAACAGATGGACTACAACGTGGTCTTGATGTTGAAGATACTGGAGATTCTATTAAAGTA
CCCGTTGGTAAAGAAACACTTGGTCGTGTTTTCAACGTCTTGGGTGACACTATCGATGGCGGCAAAGAACTTGGCCCCGA
TATAAAACGCGATCCAATCCATCGTGATCCACCAGATTATGATGAATTGAATCCAAGTACAGAAGTTCTTGAAACAGGTA
TCAAGGTTATTGACTTACTTGCCCCATATATTCGTGGTGGTAAGATTGGTCTTTTCGGAGGTGCCGGGGTTGGTAAAACC
GTTTTGATTCAAGAATTAATTCATAATATTGCACAAGAACATAATGGTATCTCAGTTTTTACTGGTGTTGGTGAAAGAAC
ACGTGAAGGTAATGACTTATACTTCGAAATGAAGGGATCCGGAGTTCTTGAACGTACGGCCATGGTATATGGTCAAATGA
ACGAGCCGCCTGGGGCTCGTATGCGAGTTGCTCTTACTGGTTTGACGATTGCGGAACATTTCCGTGATGTTGAAGGGCAA
GATGTGTTGTTATTTATTGATAACATTTTCCGTTTCACGCAAGCTGGTTCAGAAGTTTCGGCCTTACTTGGTCGTATTCC
TTCAGCCGTTGGTTACCAACCAACACTTGCTACAGAAATGGGACAACTTCAAGAACGTATTACATCAACAAAGAAGGGTT
CAGTAACATCAATCCAAGCAGTTTATGTTCCTGCTGATGATTATACTGATCCTGCTCCTGCTACAACATTTGCTCATTTG
GATGCAACTACTAACTTGGAACGTGCATTGACTCAACAAGGTATTTACCCTGCTGTGGATCCTCTTGCATCTACTTCAAC
TGCGCTTGACCCACAAATTGTTGGTGAAGAACATTATGAAGTAGCTACAGAGGTACAACATGTTCTCCAACGTTATAAGG
AATTGCAAGATATCATCTCTATCCTTGGTATGGATGAATTATCTGATGAAGAAAAGACCGTCGTTGCTCGTGCACGTCGT
ATCCAACTCTTCTTATCTCAAGACTTCAGTGTTGCTGCTCAATTTACTGGCCTTCCAGGTCACTATGTAAAGATTGAAGA
CACAATTTCTGGATTCAAGGGTATCCTTGATGGTAAGTATGATGATCTTCCTGAAGAAGCATTCCGTTTGGTTGGATCAA
TTGATGATGTAGTTGAAAAGGCTAAAAAAATAAGTGCTACAGAAGATTAG

Upstream 100 bases:

>100_bases
GTATAATCGTGCTAGACAAAGTGCTATTACGACTGAAATCACCGAAATTACTGGTGGTCAAGCTGCACTTGAATAATATT
AACGAGAGGAATTAAACGAT

Downstream 100 bases:

>100_bases
GAGGGATCTAATTGGCTGAAAATTCAGTATTAACAGTTAGTATTGTTACTCCTGATGGTCAAGTCTATGATGATGACCAA
GTTACCATGTTGGTAGTTAA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSTGKVVQVIGPVIDVEFPLDEELPTINNALKIKKADGTVLVSEVTLELGDGVVRTIAMDGTDGLQRGLDVEDTGDSIKV
PVGKETLGRVFNVLGDTIDGGKELGPDIKRDPIHRDPPDYDELNPSTEVLETGIKVIDLLAPYIRGGKIGLFGGAGVGKT
VLIQELIHNIAQEHNGISVFTGVGERTREGNDLYFEMKGSGVLERTAMVYGQMNEPPGARMRVALTGLTIAEHFRDVEGQ
DVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAVYVPADDYTDPAPATTFAHL
DATTNLERALTQQGIYPAVDPLASTSTALDPQIVGEEHYEVATEVQHVLQRYKELQDIISILGMDELSDEEKTVVARARR
IQLFLSQDFSVAAQFTGLPGHYVKIEDTISGFKGILDGKYDDLPEEAFRLVGSIDDVVEKAKKISATED

Sequences:

>Translated_469_residues
MSTGKVVQVIGPVIDVEFPLDEELPTINNALKIKKADGTVLVSEVTLELGDGVVRTIAMDGTDGLQRGLDVEDTGDSIKV
PVGKETLGRVFNVLGDTIDGGKELGPDIKRDPIHRDPPDYDELNPSTEVLETGIKVIDLLAPYIRGGKIGLFGGAGVGKT
VLIQELIHNIAQEHNGISVFTGVGERTREGNDLYFEMKGSGVLERTAMVYGQMNEPPGARMRVALTGLTIAEHFRDVEGQ
DVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAVYVPADDYTDPAPATTFAHL
DATTNLERALTQQGIYPAVDPLASTSTALDPQIVGEEHYEVATEVQHVLQRYKELQDIISILGMDELSDEEKTVVARARR
IQLFLSQDFSVAAQFTGLPGHYVKIEDTISGFKGILDGKYDDLPEEAFRLVGSIDDVVEKAKKISATED
>Mature_468_residues
STGKVVQVIGPVIDVEFPLDEELPTINNALKIKKADGTVLVSEVTLELGDGVVRTIAMDGTDGLQRGLDVEDTGDSIKVP
VGKETLGRVFNVLGDTIDGGKELGPDIKRDPIHRDPPDYDELNPSTEVLETGIKVIDLLAPYIRGGKIGLFGGAGVGKTV
LIQELIHNIAQEHNGISVFTGVGERTREGNDLYFEMKGSGVLERTAMVYGQMNEPPGARMRVALTGLTIAEHFRDVEGQD
VLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAVYVPADDYTDPAPATTFAHLD
ATTNLERALTQQGIYPAVDPLASTSTALDPQIVGEEHYEVATEVQHVLQRYKELQDIISILGMDELSDEEKTVVARARRI
QLFLSQDFSVAAQFTGLPGHYVKIEDTISGFKGILDGKYDDLPEEAFRLVGSIDDVVEKAKKISATED

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=472, Percent_Identity=66.3135593220339, Blast_Score=605, Evalue=1e-173,
Organism=Homo sapiens, GI19913424, Length=340, Percent_Identity=29.1176470588235, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI19913428, Length=408, Percent_Identity=25.2450980392157, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI19913426, Length=355, Percent_Identity=25.6338028169014, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI50345984, Length=386, Percent_Identity=25.1295336787565, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4757810, Length=386, Percent_Identity=25.1295336787565, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1790170, Length=464, Percent_Identity=66.8103448275862, Blast_Score=617, Evalue=1e-178,
Organism=Escherichia coli, GI1788251, Length=315, Percent_Identity=31.7460317460317, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790172, Length=453, Percent_Identity=25.1655629139073, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25144756, Length=472, Percent_Identity=64.1949152542373, Blast_Score=595, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17565854, Length=322, Percent_Identity=29.5031055900621, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17510931, Length=425, Percent_Identity=24.9411764705882, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=409, Percent_Identity=25.6723716381418, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71988080, Length=442, Percent_Identity=23.7556561085973, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=442, Percent_Identity=23.7556561085973, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71988074, Length=422, Percent_Identity=22.9857819905213, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322581, Length=464, Percent_Identity=69.6120689655172, Blast_Score=627, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=414, Percent_Identity=26.0869565217391, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320016, Length=260, Percent_Identity=26.9230769230769, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319370, Length=419, Percent_Identity=26.0143198090692, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24638766, Length=471, Percent_Identity=66.0297239915074, Blast_Score=596, Evalue=1e-170,
Organism=Drosophila melanogaster, GI28574560, Length=470, Percent_Identity=63.4042553191489, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI20129479, Length=319, Percent_Identity=28.8401253918495, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24583988, Length=349, Percent_Identity=27.7936962750716, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24583986, Length=349, Percent_Identity=27.7936962750716, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24583984, Length=349, Percent_Identity=27.7936962750716, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24583992, Length=322, Percent_Identity=29.1925465838509, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281361666, Length=396, Percent_Identity=26.010101010101, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646341, Length=396, Percent_Identity=26.010101010101, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136796, Length=396, Percent_Identity=26.010101010101, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24638768, Length=93, Percent_Identity=55.9139784946236, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24658560, Length=386, Percent_Identity=25.3886010362694, Blast_Score=86, Evalue=8e-17,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_PEDPA (Q03EL4)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804800.1
- ProteinModelPortal:   Q03EL4
- SMR:   Q03EL4
- STRING:   Q03EL4
- GeneID:   4417004
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1317
- NMPDR:   fig|278197.10.peg.1155
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   Q03EL4
- ProtClustDB:   PRK09280
- BioCyc:   PPEN278197:PEPE_1317-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50822; Mature: 50691

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGKVVQVIGPVIDVEFPLDEELPTINNALKIKKADGTVLVSEVTLELGDGVVRTIAMD
CCCCCEEHHHCCEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEHHHHHCCCEEEEEEEC
GTDGLQRGLDVEDTGDSIKVPVGKETLGRVFNVLGDTIDGGKELGPDIKRDPIHRDPPDY
CCHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCH
DELNPSTEVLETGIKVIDLLAPYIRGGKIGLFGGAGVGKTVLIQELIHNIAQEHNGISVF
HHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEE
TGVGERTREGNDLYFEMKGSGVLERTAMVYGQMNEPPGARMRVALTGLTIAEHFRDVEGQ
ECCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHCCCCCC
DVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQA
EEEEEHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
VYVPADDYTDPAPATTFAHLDATTNLERALTQQGIYPAVDPLASTSTALDPQIVGEEHYE
EEECCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCHHCCCCCCCCHHCCCHHHH
VATEVQHVLQRYKELQDIISILGMDELSDEEKTVVARARRIQLFLSQDFSVAAQFTGLPG
HHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHEECCCCEEEEEECCCCC
HYVKIEDTISGFKGILDGKYDDLPEEAFRLVGSIDDVVEKAKKISATED
CEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STGKVVQVIGPVIDVEFPLDEELPTINNALKIKKADGTVLVSEVTLELGDGVVRTIAMD
CCCCEEHHHCCEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEHHHHHCCCEEEEEEEC
GTDGLQRGLDVEDTGDSIKVPVGKETLGRVFNVLGDTIDGGKELGPDIKRDPIHRDPPDY
CCHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCH
DELNPSTEVLETGIKVIDLLAPYIRGGKIGLFGGAGVGKTVLIQELIHNIAQEHNGISVF
HHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEE
TGVGERTREGNDLYFEMKGSGVLERTAMVYGQMNEPPGARMRVALTGLTIAEHFRDVEGQ
ECCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHCCCCCC
DVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQA
EEEEEHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
VYVPADDYTDPAPATTFAHLDATTNLERALTQQGIYPAVDPLASTSTALDPQIVGEEHYE
EEECCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCHHCCCCCCCCHHCCCHHHH
VATEVQHVLQRYKELQDIISILGMDELSDEEKTVVARARRIQLFLSQDFSVAAQFTGLPG
HHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHEECCCCEEEEEECCCCC
HYVKIEDTISGFKGILDGKYDDLPEEAFRLVGSIDDVVEKAKKISATED
CEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA