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The map label for this gene is ywcF [H]

Identifier: 116493060

GI number: 116493060

Start: 1303353

End: 1304567

Strand: Reverse

Name: ywcF [H]

Synonym: PEPE_1312

Alternate gene names: 116493060

Gene position: 1304567-1303353 (Counterclockwise)

Preceding gene: 116493061

Following gene: 116493059

Centisome position: 71.19

GC content: 37.94

Gene sequence:

>1215_bases
ATGGAAAGAATGAATTCTAGGGTTGCTCGAAAGGATGATAGTTCCCGGATTGACTATGGAATTATTTTTCCAGTGCTAAT
GCTAGCAATTATCGGGCTGGCGTCCATCTACGTAGCTGCGACACATGATACTAGTGCTACAAGCATCTTACGACAGGTTG
TTTCTCAGTTAGTTTGGTACGTATTGGGTATCGTAATTGTCACTGTCATAATGCAATTTGATTCGAAACAATTGTGGAAA
CTAGCACCAATTGTGTATGGAATTGGACTACTTTTGTTAGTTCTAGTCTTATTTCTATACAGTCGAGCCTACGCGGCTAA
TACGGGAGCAAAGAGCTGGTTTGCTCTAGGACCCTTTACCTTCCAGCCCTCTGAAGTAATGAAACCAGCTTATATTTTGA
TGATGGCAAAAGTTATTACGGTTTACAACTCAAAAGTAAAAGAGCGCACAGTCCGCAGTGATTGGAAGCTTATCGGAACA
ATGATTTTATGGACTTTACCAGTGCCTATCTTGTTATTGTTGCAACATGACTTTGGCACGATGTTAGTGTTTATTGCTAT
TTTTGCTGGATTAGTCGTGGTTTCGGGAGTTACTTGGCGAATTTTGGTACCGTCTTTTGTTGGAATGGTGGTATTAGGAA
GTTCAACCTTGATGCTGGTCGCTACAAGTTGGGGACAATCGTTTTTGAGTAAGTTAGGTTTTGAATCTTATCAATTTGCT
CGAATCGATAATTGGTTGCATCCTGCTTCGGATACTACTAATTCAGGTTATCAATTATGGCAAAGTATGAAAGCTATCGG
TTCTGGGCAATTATTTGGAAAAGGTTTCAACGTTTCGAACGTTAACGTTCCGGTTCGAGAATCTGATATGATTTTTTCGG
TTATTGGAGAAAATTTTGGATTTGTCGGTAGTGTAGTATTAATTGGACTATACTTTTTATTAATTTATAAAATTATCCAA
GTCATTTTTGATACTAAAAATGAATTTTATGCGTATATAGCAGTGGGAGTTATCATGATGATTCTATTCCATGTATTTGA
AAATATTGGAATGAACATCGGGCTTTTACCACTAACTGGAATTCCGCTACCGTTTGTTAGTGCAGGAGGTTCGGCATTGA
TCGGAAATATGATTGGCGTGGGGTTAATCATGTCGATGAGGTACCATTATTATTCTTATAGTAAAACAGGATTAGAACAA
AAAGCTGATTTCTAA

Upstream 100 bases:

>100_bases
TAACCAAAGTGGAGAAATGCGTGTAAAATCTATGGATGAAGGAATTCAATGGATTGTAGCTGAATTTAACCTACATTCTC
TATAGAAAGGAGCTACCTCG

Downstream 100 bases:

>100_bases
AAAACTAGTGATACAAATTAGGTATCCTAGTTTTTTTATTTTAGTGTTGACAGCTAAACTGATGGCATGTATACTTTAGC
CTATTAACAAAGTATTAGAG

Product: cell division membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MERMNSRVARKDDSSRIDYGIIFPVLMLAIIGLASIYVAATHDTSATSILRQVVSQLVWYVLGIVIVTVIMQFDSKQLWK
LAPIVYGIGLLLLVLVLFLYSRAYAANTGAKSWFALGPFTFQPSEVMKPAYILMMAKVITVYNSKVKERTVRSDWKLIGT
MILWTLPVPILLLLQHDFGTMLVFIAIFAGLVVVSGVTWRILVPSFVGMVVLGSSTLMLVATSWGQSFLSKLGFESYQFA
RIDNWLHPASDTTNSGYQLWQSMKAIGSGQLFGKGFNVSNVNVPVRESDMIFSVIGENFGFVGSVVLIGLYFLLIYKIIQ
VIFDTKNEFYAYIAVGVIMMILFHVFENIGMNIGLLPLTGIPLPFVSAGGSALIGNMIGVGLIMSMRYHYYSYSKTGLEQ
KADF

Sequences:

>Translated_404_residues
MERMNSRVARKDDSSRIDYGIIFPVLMLAIIGLASIYVAATHDTSATSILRQVVSQLVWYVLGIVIVTVIMQFDSKQLWK
LAPIVYGIGLLLLVLVLFLYSRAYAANTGAKSWFALGPFTFQPSEVMKPAYILMMAKVITVYNSKVKERTVRSDWKLIGT
MILWTLPVPILLLLQHDFGTMLVFIAIFAGLVVVSGVTWRILVPSFVGMVVLGSSTLMLVATSWGQSFLSKLGFESYQFA
RIDNWLHPASDTTNSGYQLWQSMKAIGSGQLFGKGFNVSNVNVPVRESDMIFSVIGENFGFVGSVVLIGLYFLLIYKIIQ
VIFDTKNEFYAYIAVGVIMMILFHVFENIGMNIGLLPLTGIPLPFVSAGGSALIGNMIGVGLIMSMRYHYYSYSKTGLEQ
KADF
>Mature_404_residues
MERMNSRVARKDDSSRIDYGIIFPVLMLAIIGLASIYVAATHDTSATSILRQVVSQLVWYVLGIVIVTVIMQFDSKQLWK
LAPIVYGIGLLLLVLVLFLYSRAYAANTGAKSWFALGPFTFQPSEVMKPAYILMMAKVITVYNSKVKERTVRSDWKLIGT
MILWTLPVPILLLLQHDFGTMLVFIAIFAGLVVVSGVTWRILVPSFVGMVVLGSSTLMLVATSWGQSFLSKLGFESYQFA
RIDNWLHPASDTTNSGYQLWQSMKAIGSGQLFGKGFNVSNVNVPVRESDMIFSVIGENFGFVGSVVLIGLYFLLIYKIIQ
VIFDTKNEFYAYIAVGVIMMILFHVFENIGMNIGLLPLTGIPLPFVSAGGSALIGNMIGVGLIMSMRYHYYSYSKTGLEQ
KADF

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=345, Percent_Identity=35.9420289855072, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786277, Length=361, Percent_Identity=25.7617728531856, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44849; Mature: 44849

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERMNSRVARKDDSSRIDYGIIFPVLMLAIIGLASIYVAATHDTSATSILRQVVSQLVWY
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHH
VLGIVIVTVIMQFDSKQLWKLAPIVYGIGLLLLVLVLFLYSRAYAANTGAKSWFALGPFT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
FQPSEVMKPAYILMMAKVITVYNSKVKERTVRSDWKLIGTMILWTLPVPILLLLQHDFGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
MLVFIAIFAGLVVVSGVTWRILVPSFVGMVVLGSSTLMLVATSWGQSFLSKLGFESYQFA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHCCCCCCHHH
RIDNWLHPASDTTNSGYQLWQSMKAIGSGQLFGKGFNVSNVNVPVRESDMIFSVIGENFG
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCC
FVGSVVLIGLYFLLIYKIIQVIFDTKNEFYAYIAVGVIMMILFHVFENIGMNIGLLPLTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
IPLPFVSAGGSALIGNMIGVGLIMSMRYHYYSYSKTGLEQKADF
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MERMNSRVARKDDSSRIDYGIIFPVLMLAIIGLASIYVAATHDTSATSILRQVVSQLVWY
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHH
VLGIVIVTVIMQFDSKQLWKLAPIVYGIGLLLLVLVLFLYSRAYAANTGAKSWFALGPFT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
FQPSEVMKPAYILMMAKVITVYNSKVKERTVRSDWKLIGTMILWTLPVPILLLLQHDFGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
MLVFIAIFAGLVVVSGVTWRILVPSFVGMVVLGSSTLMLVATSWGQSFLSKLGFESYQFA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHCCCCCCHHH
RIDNWLHPASDTTNSGYQLWQSMKAIGSGQLFGKGFNVSNVNVPVRESDMIFSVIGENFG
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCC
FVGSVVLIGLYFLLIYKIIQVIFDTKNEFYAYIAVGVIMMILFHVFENIGMNIGLLPLTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
IPLPFVSAGGSALIGNMIGVGLIMSMRYHYYSYSKTGLEQKADF
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]