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The map label for this gene is yfnA [H]

Identifier: 116493052

GI number: 116493052

Start: 1296010

End: 1297431

Strand: Direct

Name: yfnA [H]

Synonym: PEPE_1304

Alternate gene names: 116493052

Gene position: 1296010-1297431 (Clockwise)

Preceding gene: 116493048

Following gene: 116493080

Centisome position: 70.73

GC content: 41.42

Gene sequence:

>1422_bases
TTGCATAATTTCATCAAAAATTTTATTAAAAAAGAAAATCCTGCTATTTATGAAGATAAAGATTCTCATTTGACTCGTAC
CCTAGTAGTCAAAGACTTTTTAGCTCTTGGGGTTGGGACGATCGTTTCCACCTCCATCTTCACACTTCCTGGTGTGGTTG
CAGCTCAACATGCTGGTCCAGCCGTCGTACTTTCATTCTTAGCAGCAGCTGTAGTTGCCGGCCTAGTAGCCTTTGCTTAT
GCCGAAATGGCTTCCGCTATGCCATTTGCTGGATCTGCATACTCTTGGATTAACGTAATCTTAGGTAAAGGGTTTGGTTG
GGTAGCCGGCTGGGCTTTGTTAGCGGAATATTTCATCGCCGTAGCCTTCGTGGCCTCCGGACTTTCAGCTAACTTTAGGG
GACTGCTTTCCTCAATTGGAATCCAAATTCCCAAACAGCTTGCAAATCCTCTAGGTACTAATGGTGGAATCATTGATATT
ACTGCGTTGATCGTCGTTATTGCGGTAGCGTTACTTTTAGCTCATGGAACTACAGGAGCCGCTCGCATCGAAAATGCACT
CGTTGTTTTAAAGGTTGTTGCTATTTTAGTATTTATTATTGTGGGACTTTCAGCTATCCATATTCAAAACTACCTACCAT
TTATCCCTAAATATCATACCAACCCAGACGGAACTTCCTTTGGTGGATGGAAAGGTATCTATTCGGGAATTTCAATGATT
TTTCTTTCCTATATTGGTTTTGATTCAATTGCTGCTAATGCCGGAGAAGCTAAAAACCCTGAAAAAACTATGCCTCGCGG
TATTTTAGGATCGTTAATAATTGCTGTTATCCTTTTTATTGCAGTTTCGCTAGTGCTAGTTGGAATGTTTCATTACACGA
ATTACGCTAATAATGCTGAACCTGTCGGTTGGGCCTTACGACACGCTGGTCACGGAGTAATTGCTGGTGTGATTCAAGCA
ATTGCCGTAATTGGGATGTTTACAGCATTAATTGGCATGATGATGGCTGGTTCTCGTCTGCTATACTCATTTGGACGTGA
TGGTATGCTACCTAAATGGTTAGGTCAAGTAAATCCAAAAGGTCTTCCTAACCATGCATTAAGCCTTTTAACAATTATCG
GCATTATTATTGGTTCCATGTTTCCTTTTGCTTTCTTAGCGCAATTAATCTCAGCTGGGACCTTAATCGCCTTTATGTTT
GTATCGTTAGGGATCTATGTCCTGCGACCTCGTGAAGGTAAAGATATTGCTATTCCAAGCTTCAAAATGCCGCTCTACCC
TGTTCTTCCTGCCTTGGCTTTCTTAGGCTCTCTGGCAGTTTTCTGGGGACTAGACGCCCAAGCTAAATTATACTCACTAG
TTTGGTTTATCATTGGAATTATTGTTTACACTTTCTACGGAGCAAGACATACTACAGATTAA

Upstream 100 bases:

>100_bases
TTCACTTAAAAATACAATTAAATTTGATTAGCTAAACATTAAAAATAAATGATAGAATATGATATGATAGTCTATACTAC
TATTTAAGGAGGTTAAATTA

Downstream 100 bases:

>100_bases
AAAACGCATCTAAACTTAGCTTTTAACTAAGTTTAGATGCGTTTTTGTCATCCAAATATTTCTGGAAGAATTTGTTGACC
ACGCTGTTCAACTAAATTTT

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MHNFIKNFIKKENPAIYEDKDSHLTRTLVVKDFLALGVGTIVSTSIFTLPGVVAAQHAGPAVVLSFLAAAVVAGLVAFAY
AEMASAMPFAGSAYSWINVILGKGFGWVAGWALLAEYFIAVAFVASGLSANFRGLLSSIGIQIPKQLANPLGTNGGIIDI
TALIVVIAVALLLAHGTTGAARIENALVVLKVVAILVFIIVGLSAIHIQNYLPFIPKYHTNPDGTSFGGWKGIYSGISMI
FLSYIGFDSIAANAGEAKNPEKTMPRGILGSLIIAVILFIAVSLVLVGMFHYTNYANNAEPVGWALRHAGHGVIAGVIQA
IAVIGMFTALIGMMMAGSRLLYSFGRDGMLPKWLGQVNPKGLPNHALSLLTIIGIIIGSMFPFAFLAQLISAGTLIAFMF
VSLGIYVLRPREGKDIAIPSFKMPLYPVLPALAFLGSLAVFWGLDAQAKLYSLVWFIIGIIVYTFYGARHTTD

Sequences:

>Translated_473_residues
MHNFIKNFIKKENPAIYEDKDSHLTRTLVVKDFLALGVGTIVSTSIFTLPGVVAAQHAGPAVVLSFLAAAVVAGLVAFAY
AEMASAMPFAGSAYSWINVILGKGFGWVAGWALLAEYFIAVAFVASGLSANFRGLLSSIGIQIPKQLANPLGTNGGIIDI
TALIVVIAVALLLAHGTTGAARIENALVVLKVVAILVFIIVGLSAIHIQNYLPFIPKYHTNPDGTSFGGWKGIYSGISMI
FLSYIGFDSIAANAGEAKNPEKTMPRGILGSLIIAVILFIAVSLVLVGMFHYTNYANNAEPVGWALRHAGHGVIAGVIQA
IAVIGMFTALIGMMMAGSRLLYSFGRDGMLPKWLGQVNPKGLPNHALSLLTIIGIIIGSMFPFAFLAQLISAGTLIAFMF
VSLGIYVLRPREGKDIAIPSFKMPLYPVLPALAFLGSLAVFWGLDAQAKLYSLVWFIIGIIVYTFYGARHTTD
>Mature_473_residues
MHNFIKNFIKKENPAIYEDKDSHLTRTLVVKDFLALGVGTIVSTSIFTLPGVVAAQHAGPAVVLSFLAAAVVAGLVAFAY
AEMASAMPFAGSAYSWINVILGKGFGWVAGWALLAEYFIAVAFVASGLSANFRGLLSSIGIQIPKQLANPLGTNGGIIDI
TALIVVIAVALLLAHGTTGAARIENALVVLKVVAILVFIIVGLSAIHIQNYLPFIPKYHTNPDGTSFGGWKGIYSGISMI
FLSYIGFDSIAANAGEAKNPEKTMPRGILGSLIIAVILFIAVSLVLVGMFHYTNYANNAEPVGWALRHAGHGVIAGVIQA
IAVIGMFTALIGMMMAGSRLLYSFGRDGMLPKWLGQVNPKGLPNHALSLLTIIGIIIGSMFPFAFLAQLISAGTLIAFMF
VSLGIYVLRPREGKDIAIPSFKMPLYPVLPALAFLGSLAVFWGLDAQAKLYSLVWFIIGIIVYTFYGARHTTD

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=439, Percent_Identity=28.0182232346241, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI258614005, Length=440, Percent_Identity=27.9545454545455, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI258614003, Length=440, Percent_Identity=27.9545454545455, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI4507047, Length=421, Percent_Identity=30.166270783848, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI181337167, Length=407, Percent_Identity=30.2211302211302, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI114326544, Length=419, Percent_Identity=28.4009546539379, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI114326550, Length=419, Percent_Identity=28.4009546539379, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI110347453, Length=406, Percent_Identity=28.0788177339901, Blast_Score=119, Evalue=9e-27,
Organism=Escherichia coli, GI87082250, Length=464, Percent_Identity=26.5086206896552, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87081708, Length=446, Percent_Identity=22.1973094170404, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786789, Length=452, Percent_Identity=24.5575221238938, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788480, Length=460, Percent_Identity=24.1304347826087, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI48994972, Length=422, Percent_Identity=25.5924170616114, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786302, Length=418, Percent_Identity=21.2918660287081, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790653, Length=492, Percent_Identity=22.9674796747967, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081869, Length=467, Percent_Identity=23.7687366167024, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786602, Length=416, Percent_Identity=20.9134615384615, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789017, Length=421, Percent_Identity=24.4655581947743, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082023, Length=469, Percent_Identity=23.454157782516, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI2367353, Length=367, Percent_Identity=23.1607629427793, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786908, Length=296, Percent_Identity=23.3108108108108, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=397, Percent_Identity=31.2342569269521, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17532491, Length=435, Percent_Identity=28.735632183908, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17533459, Length=400, Percent_Identity=30.25, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324061, Length=448, Percent_Identity=23.8839285714286, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321053, Length=444, Percent_Identity=23.8738738738739, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320251, Length=411, Percent_Identity=19.4647201946472, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321629, Length=393, Percent_Identity=21.3740458015267, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324059, Length=239, Percent_Identity=25.9414225941423, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319542, Length=394, Percent_Identity=22.0812182741117, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24668806, Length=434, Percent_Identity=31.7972350230415, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21356285, Length=434, Percent_Identity=31.7972350230415, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24668802, Length=434, Percent_Identity=31.7972350230415, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI221512776, Length=425, Percent_Identity=31.0588235294118, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24666159, Length=425, Percent_Identity=31.0588235294118, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24667468, Length=412, Percent_Identity=30.0970873786408, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI281366235, Length=407, Percent_Identity=30.2211302211302, Blast_Score=145, Evalue=8e-35,
Organism=Drosophila melanogaster, GI116007820, Length=407, Percent_Identity=30.2211302211302, Blast_Score=145, Evalue=8e-35,
Organism=Drosophila melanogaster, GI161077963, Length=411, Percent_Identity=27.7372262773723, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI116007818, Length=403, Percent_Identity=29.7766749379653, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI85725152, Length=403, Percent_Identity=29.7766749379653, Blast_Score=141, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50289; Mature: 50289

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]