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The map label for this gene is pgsA [H]

Identifier: 116493026

GI number: 116493026

Start: 1268917

End: 1269498

Strand: Reverse

Name: pgsA [H]

Synonym: PEPE_1278

Alternate gene names: 116493026

Gene position: 1269498-1268917 (Counterclockwise)

Preceding gene: 116493027

Following gene: 116493025

Centisome position: 69.28

GC content: 34.02

Gene sequence:

>582_bases
ATGAATTTACCTAATAAATTAACCATTTTTAGAATAATTTTAATTCCAATTTTTATCATACTCACAGTCATGCCAGAAGT
TGGTGGAAGTGTAGTTTGGTTGGGGACAAGTATTGCAGTTACCAAGATTTGGGGGGCACTTGTTTTTGCAATTGCATCTA
TTACCGATTTTTTAGATGGACAGATTGCTAGACGTCAACATTTGGTTACCAATTTTGGTAAATTTGCTGATCCAATTGCA
GATAAAATGTTAGTAATGACTGCTTTTATTGTCTTAGTAGAAATGAAGATGGTTCCAGCTTGGATTGCTGCTATCATCGT
TTGTCGTGAGTTAGCTATTAGTGGATTGCGCTTAATCATTGTGGAAAATGATGGTGAGGTACTAGCAGCTGAAATGCCTG
GAAAAATCAAAACATTCTCGCAAATGTTCGCGATTATTTTCTTGCTTTTGAATAACATTTTCTCAAGTTTCTTACATTTC
GGTCTAGGTACAGTATTATTATATGTCTGCTTATTCTTTACTGTTTATTCAGGAATCGATTATTTTTATAAGAATCGGGC
CATTTTTTCTGATTCATTCTAG

Upstream 100 bases:

>100_bases
TGGGTTTACGGGAACGATTGCCGGAAAAGAAATACCTAAATCAACTACCAATTCGGTGGTTCGAAATATAACAATTGAAG
TAAAATAAGAGGGAGTATCA

Downstream 100 bases:

>100_bases
TAATATAAAGGACTATAGCGAAATTTATGATTTTGTTATGGACCTTTTTTTAATACAAAAAAATAAAAACGAGTAAAATT
ACATATATAAGCATTGAGGA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MNLPNKLTIFRIILIPIFIILTVMPEVGGSVVWLGTSIAVTKIWGALVFAIASITDFLDGQIARRQHLVTNFGKFADPIA
DKMLVMTAFIVLVEMKMVPAWIAAIIVCRELAISGLRLIIVENDGEVLAAEMPGKIKTFSQMFAIIFLLLNNIFSSFLHF
GLGTVLLYVCLFFTVYSGIDYFYKNRAIFSDSF

Sequences:

>Translated_193_residues
MNLPNKLTIFRIILIPIFIILTVMPEVGGSVVWLGTSIAVTKIWGALVFAIASITDFLDGQIARRQHLVTNFGKFADPIA
DKMLVMTAFIVLVEMKMVPAWIAAIIVCRELAISGLRLIIVENDGEVLAAEMPGKIKTFSQMFAIIFLLLNNIFSSFLHF
GLGTVLLYVCLFFTVYSGIDYFYKNRAIFSDSF
>Mature_193_residues
MNLPNKLTIFRIILIPIFIILTVMPEVGGSVVWLGTSIAVTKIWGALVFAIASITDFLDGQIARRQHLVTNFGKFADPIA
DKMLVMTAFIVLVEMKMVPAWIAAIIVCRELAISGLRLIIVENDGEVLAAEMPGKIKTFSQMFAIIFLLLNNIFSSFLHF
GLGTVLLYVCLFFTVYSGIDYFYKNRAIFSDSF

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=196, Percent_Identity=36.2244897959184, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320059, Length=122, Percent_Identity=39.344262295082, Blast_Score=61, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24650130, Length=144, Percent_Identity=34.7222222222222, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24650126, Length=144, Percent_Identity=34.7222222222222, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24650128, Length=144, Percent_Identity=34.7222222222222, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21538; Mature: 21538

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKLTIFRIILIPIFIILTVMPEVGGSVVWLGTSIAVTKIWGALVFAIASITDFLDG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
QIARRQHLVTNFGKFADPIADKMLVMTAFIVLVEMKMVPAWIAAIIVCRELAISGLRLII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
VENDGEVLAAEMPGKIKTFSQMFAIIFLLLNNIFSSFLHFGLGTVLLYVCLFFTVYSGID
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFYKNRAIFSDSF
HHHHCCCCCCCCC
>Mature Secondary Structure
MNLPNKLTIFRIILIPIFIILTVMPEVGGSVVWLGTSIAVTKIWGALVFAIASITDFLDG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
QIARRQHLVTNFGKFADPIADKMLVMTAFIVLVEMKMVPAWIAAIIVCRELAISGLRLII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
VENDGEVLAAEMPGKIKTFSQMFAIIFLLLNNIFSSFLHFGLGTVLLYVCLFFTVYSGID
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFYKNRAIFSDSF
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]