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The map label for this gene is ccpA [H]

Identifier: 116492998

GI number: 116492998

Start: 1236080

End: 1237084

Strand: Reverse

Name: ccpA [H]

Synonym: PEPE_1250

Alternate gene names: 116492998

Gene position: 1237084-1236080 (Counterclockwise)

Preceding gene: 116493000

Following gene: 116492996

Centisome position: 67.51

GC content: 37.11

Gene sequence:

>1005_bases
ATGGCAAAACAAACCATCACAATTTACGATGTTGCTCGAGAAGCGGGCGTTTCAATGGCCACAGTATCACGCGTTGTTAA
TGGAAATCCTAATGTTAAACCTGTTACAAGAAAAAAGGTTAACGAAGTAATCGAACGTTTGGATTACCATCCCAATGCAG
TAGCTCGTGGTCTTGCTAGCAAGAGATCAACTACTATTGGAGTAATTCTACCAGATATTACTCAAATGTTTTTTGCATCG
TTAGCACGAGGAATTGATGATATTGCTTCAATGTACAAATACAATATCATTTTAGAAAATTCTGACGAAGATGTTGATAA
AAAGGTTGAAGTGCTTGAAAACTTACAAGCTAAGCAAGTAGACGGTATCATTTATATGGGGAATGCCGTTGACGATCGTT
TACGAGAAGCGTTTAAAGCAGCTCGTACACCAGTCGTTTTTGCTGGTTCCGTAGATGATAAGAACACTTTGCCTTCTGTA
AGTATCGATAATAAGGCTGCAGTATACGAAGCAGTCAATAAACTAATTGATAATAAAAATAAGAAGATTGCTTTTATCTC
AGGTCCGCTTTCTGAACCCGTTAATGGTAAATTTAGATTAGAAGGTTATCGTCTTGCTTTAAGTGAAGCTAAAGTTGATT
ATGACGAAAATCTAGTTTTTGAAACAAGTAATACTTACGAAGATGGAGTTAAGTTAGCATCCGAAATTGCTTCTACAACG
GGCGTTACGGCCGCTTTTGTTGCTAATGATAGTTTAGCGGTGGGCTTACTTAACGGCCTTCAAGATCTCGGCGTTAAAGT
TCCGGAAGATTTCGAAATTATTTCAAGTAATAATACTAGCTTGACTAAGATGGTTCGTCCACAAATTAGTTCAATTGGTC
ACCCAATGTACGATACTGGGGCGGTTGCAATGCGTCTTTTAACTAAATTAATGAATAAAGAAGAAGTCGAAGAACGTAAT
ATTACTCTTCCATTTGATATGGTCTTCAGACAATCTACTAAATAA

Upstream 100 bases:

>100_bases
AATAAAAAAAGGTTGCAAGTATGCTGAAAATTTGATAACGTATTCATGGCAATGAAAACAGAATGAAAACAAATAATATC
AATGGAAGAGGTAATATAAT

Downstream 100 bases:

>100_bases
AAGAAAAAATCCACTTCTACATTAGGTAGAAGCGGATTTTTTGTTTAATTATATGTTATAGGAAAAGTCCTTTATACAAA
GCAACGGCACAAATACCAGC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAKQTITIYDVAREAGVSMATVSRVVNGNPNVKPVTRKKVNEVIERLDYHPNAVARGLASKRSTTIGVILPDITQMFFAS
LARGIDDIASMYKYNIILENSDEDVDKKVEVLENLQAKQVDGIIYMGNAVDDRLREAFKAARTPVVFAGSVDDKNTLPSV
SIDNKAAVYEAVNKLIDNKNKKIAFISGPLSEPVNGKFRLEGYRLALSEAKVDYDENLVFETSNTYEDGVKLASEIASTT
GVTAAFVANDSLAVGLLNGLQDLGVKVPEDFEIISSNNTSLTKMVRPQISSIGHPMYDTGAVAMRLLTKLMNKEEVEERN
ITLPFDMVFRQSTK

Sequences:

>Translated_334_residues
MAKQTITIYDVAREAGVSMATVSRVVNGNPNVKPVTRKKVNEVIERLDYHPNAVARGLASKRSTTIGVILPDITQMFFAS
LARGIDDIASMYKYNIILENSDEDVDKKVEVLENLQAKQVDGIIYMGNAVDDRLREAFKAARTPVVFAGSVDDKNTLPSV
SIDNKAAVYEAVNKLIDNKNKKIAFISGPLSEPVNGKFRLEGYRLALSEAKVDYDENLVFETSNTYEDGVKLASEIASTT
GVTAAFVANDSLAVGLLNGLQDLGVKVPEDFEIISSNNTSLTKMVRPQISSIGHPMYDTGAVAMRLLTKLMNKEEVEERN
ITLPFDMVFRQSTK
>Mature_333_residues
AKQTITIYDVAREAGVSMATVSRVVNGNPNVKPVTRKKVNEVIERLDYHPNAVARGLASKRSTTIGVILPDITQMFFASL
ARGIDDIASMYKYNIILENSDEDVDKKVEVLENLQAKQVDGIIYMGNAVDDRLREAFKAARTPVVFAGSVDDKNTLPSVS
IDNKAAVYEAVNKLIDNKNKKIAFISGPLSEPVNGKFRLEGYRLALSEAKVDYDENLVFETSNTYEDGVKLASEIASTTG
VTAAFVANDSLAVGLLNGLQDLGVKVPEDFEIISSNNTSLTKMVRPQISSIGHPMYDTGAVAMRLLTKLMNKEEVEERNI
TLPFDMVFRQSTK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=31.4199395770393, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788474, Length=303, Percent_Identity=29.042904290429, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=29.2168674698795, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=29.6969696969697, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789202, Length=291, Percent_Identity=26.4604810996564, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=27.4924471299094, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789068, Length=294, Percent_Identity=28.2312925170068, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI48994940, Length=334, Percent_Identity=27.5449101796407, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=27.7611940298507, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787906, Length=335, Percent_Identity=25.6716417910448, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1790715, Length=318, Percent_Identity=24.2138364779874, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790689, Length=320, Percent_Identity=24.0625, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786268, Length=311, Percent_Identity=25.4019292604502, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789456, Length=299, Percent_Identity=28.0936454849498, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36690; Mature: 36559

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQTITIYDVAREAGVSMATVSRVVNGNPNVKPVTRKKVNEVIERLDYHPNAVARGLAS
CCCCEEEHEEHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
KRSTTIGVILPDITQMFFASLARGIDDIASMYKYNIILENSDEDVDKKVEVLENLQAKQV
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHC
DGIIYMGNAVDDRLREAFKAARTPVVFAGSVDDKNTLPSVSIDNKAAVYEAVNKLIDNKN
CCEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
KKIAFISGPLSEPVNGKFRLEGYRLALSEAKVDYDENLVFETSNTYEDGVKLASEIASTT
CEEEEEECCCCCCCCCEEEEEEEEEEEEHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHC
GVTAAFVANDSLAVGLLNGLQDLGVKVPEDFEIISSNNTSLTKMVRPQISSIGHPMYDTG
CCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCHH
AVAMRLLTKLMNKEEVEERNITLPFDMVFRQSTK
HHHHHHHHHHHCHHHHHHCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
AKQTITIYDVAREAGVSMATVSRVVNGNPNVKPVTRKKVNEVIERLDYHPNAVARGLAS
CCCEEEHEEHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
KRSTTIGVILPDITQMFFASLARGIDDIASMYKYNIILENSDEDVDKKVEVLENLQAKQV
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHC
DGIIYMGNAVDDRLREAFKAARTPVVFAGSVDDKNTLPSVSIDNKAAVYEAVNKLIDNKN
CCEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
KKIAFISGPLSEPVNGKFRLEGYRLALSEAKVDYDENLVFETSNTYEDGVKLASEIASTT
CEEEEEECCCCCCCCCEEEEEEEEEEEEHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHC
GVTAAFVANDSLAVGLLNGLQDLGVKVPEDFEIISSNNTSLTKMVRPQISSIGHPMYDTG
CCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCHH
AVAMRLLTKLMNKEEVEERNITLPFDMVFRQSTK
HHHHHHHHHHHCHHHHHHCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]