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The map label for this gene is yifK [H]

Identifier: 116492633

GI number: 116492633

Start: 868600

End: 869976

Strand: Direct

Name: yifK [H]

Synonym: PEPE_0867

Alternate gene names: 116492633

Gene position: 868600-869976 (Clockwise)

Preceding gene: 116492632

Following gene: 116492634

Centisome position: 47.4

GC content: 37.76

Gene sequence:

>1377_bases
ATGAAGGAAGATTTACCGCAGTTAAAACGATCACTTACATCAAACCAAATGCAAATGATTGCATTAGGAGGAACCATTGG
TGTGGGATTGTTCATGGGATCCTCATCGACAATTAAGTGGACGGGACCATCAGTGTTGCTAGCATATGGCTTTGCGGGGT
TAATATTGTACCTAGTTATGCGTGCTTTAGGGGAGATTTTATATGTAAACCCAAGCACCGGTTCCTTTGCTGATTATGCA
ACCAACTATATTCACCCCTTAGCAGGATATTTAACCATGTGGAGCAATATCTTCCAATTTATTGTAGTTGGGATTAGCGA
AGTGGTTGCAGTTAGTCAATATTTGAATTACTGGTGGCCAAATTTACCAGGGTGGGTTTCTAGTGTGGTGGTAATTGCTA
CTTTAACGCTTGCTAACTTGGTTTCTACTAAAGCATACGGAGCGATTGAATTCTATTTTGCTTTAATTAAAGTGCTAACG
ATTATTTTAATGATTATTATTGGTGTTTTAGTGATTTTCATGGGCTTAGGTAATCATTGGCGCCCTGTAGGATTGAGCAA
TCTTTGGGCTCACGGGGGCTTTTTTACAGGTGGAGTTAAAGGATTCTTGTTTGCATTATCAATCGTTGTAGGCTCTTACC
AAGGAATTGAGTTACTTGGTATCACTGCTGGTGAAGCAGCTAATCCTAAAAAGGCCATTGTGGCTTCGGTAAAATCAATT
GTTTGGCGAATTTTAATTTTTTATTTAGGAGCAATCTTTGTTATCGTAGCTATTTTTCCTTGGAATCAATTGGCTACGGT
AGGTTCTCCGTTTGTGGAAACTTTTTCAAAAGTAGGAATTACCGGAGCGGCTGGAATTATCAATTTTGTTGTTTTAACTG
CGGCAATGTCAGGAACCAATTCTGGAATTTATAGTGCTAGTCGAATGTTGTATAAACTATCTCAAGAAGGAAAGGTACCT
AAGATTTTTGGTAAATTATCCAGTCATCGAGTTCCATCTGTAGCAATCTTGACCATATCTTTTGGAATTTTGTTAGGGAT
TATCTTAAATATCTTCTTATCTTCATTTAAAGGAGGAGCTGTTAACCTATTTGTGCTGATATATAGTTCGAGTGTGTTGC
CGGGGATGGTTCCATGGTTTGTTATCCTACTTTCTGAATTACGCTTTCGCCGTGCTAACCCAGAAATAATTCAAAATCAT
CCTTTTGTAATGCCGCTTTATCCCATGAGTAATTACTTAGCGATTATCTCGTTACTTTTGATTGTAGTTTTTATGTTCAT
CAATCCAGACACGAGGGCATCAGTTACAGTAGGATTTGTTTTTCTAATGGTTTTAACGATTAATTTTATAATTAAATTCC
GCCGTAAACGGGGTTAG

Upstream 100 bases:

>100_bases
TTAAAATTTGGTTAACAAACAAAACCACCCAATCAGAATTCAGTGCCTACTAGCATTGATACTGATTCGGTGGTTTTTTA
TATTTTGAGGAGGAAGAACA

Downstream 100 bases:

>100_bases
AAAAAATTCAGAAAGCTAAAGTTCTGAAGCTTTTAATATTTTAAAGGAAAAGATATTGCTAAGGTTTACCTAAGAAATAA
GCTGAACTTTGATAAACAGA

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKEDLPQLKRSLTSNQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLLAYGFAGLILYLVMRALGEILYVNPSTGSFADYA
TNYIHPLAGYLTMWSNIFQFIVVGISEVVAVSQYLNYWWPNLPGWVSSVVVIATLTLANLVSTKAYGAIEFYFALIKVLT
IILMIIIGVLVIFMGLGNHWRPVGLSNLWAHGGFFTGGVKGFLFALSIVVGSYQGIELLGITAGEAANPKKAIVASVKSI
VWRILIFYLGAIFVIVAIFPWNQLATVGSPFVETFSKVGITGAAGIINFVVLTAAMSGTNSGIYSASRMLYKLSQEGKVP
KIFGKLSSHRVPSVAILTISFGILLGIILNIFLSSFKGGAVNLFVLIYSSSVLPGMVPWFVILLSELRFRRANPEIIQNH
PFVMPLYPMSNYLAIISLLLIVVFMFINPDTRASVTVGFVFLMVLTINFIIKFRRKRG

Sequences:

>Translated_458_residues
MKEDLPQLKRSLTSNQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLLAYGFAGLILYLVMRALGEILYVNPSTGSFADYA
TNYIHPLAGYLTMWSNIFQFIVVGISEVVAVSQYLNYWWPNLPGWVSSVVVIATLTLANLVSTKAYGAIEFYFALIKVLT
IILMIIIGVLVIFMGLGNHWRPVGLSNLWAHGGFFTGGVKGFLFALSIVVGSYQGIELLGITAGEAANPKKAIVASVKSI
VWRILIFYLGAIFVIVAIFPWNQLATVGSPFVETFSKVGITGAAGIINFVVLTAAMSGTNSGIYSASRMLYKLSQEGKVP
KIFGKLSSHRVPSVAILTISFGILLGIILNIFLSSFKGGAVNLFVLIYSSSVLPGMVPWFVILLSELRFRRANPEIIQNH
PFVMPLYPMSNYLAIISLLLIVVFMFINPDTRASVTVGFVFLMVLTINFIIKFRRKRG
>Mature_458_residues
MKEDLPQLKRSLTSNQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLLAYGFAGLILYLVMRALGEILYVNPSTGSFADYA
TNYIHPLAGYLTMWSNIFQFIVVGISEVVAVSQYLNYWWPNLPGWVSSVVVIATLTLANLVSTKAYGAIEFYFALIKVLT
IILMIIIGVLVIFMGLGNHWRPVGLSNLWAHGGFFTGGVKGFLFALSIVVGSYQGIELLGITAGEAANPKKAIVASVKSI
VWRILIFYLGAIFVIVAIFPWNQLATVGSPFVETFSKVGITGAAGIINFVVLTAAMSGTNSGIYSASRMLYKLSQEGKVP
KIFGKLSSHRVPSVAILTISFGILLGIILNIFLSSFKGGAVNLFVLIYSSSVLPGMVPWFVILLSELRFRRANPEIIQNH
PFVMPLYPMSNYLAIISLLLIVVFMFINPDTRASVTVGFVFLMVLTINFIIKFRRKRG

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994972, Length=447, Percent_Identity=54.3624161073826, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1786602, Length=456, Percent_Identity=42.3245614035088, Blast_Score=342, Evalue=3e-95,
Organism=Escherichia coli, GI1790653, Length=454, Percent_Identity=38.3259911894273, Blast_Score=321, Evalue=6e-89,
Organism=Escherichia coli, GI1786789, Length=451, Percent_Identity=39.0243902439024, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1786302, Length=456, Percent_Identity=37.0614035087719, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1788480, Length=434, Percent_Identity=36.1751152073733, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI87081708, Length=447, Percent_Identity=35.7941834451902, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789017, Length=431, Percent_Identity=35.9628770301624, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI87081915, Length=409, Percent_Identity=32.2738386308068, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI2367353, Length=408, Percent_Identity=23.0392156862745, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790575, Length=245, Percent_Identity=22.4489795918367, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324061, Length=475, Percent_Identity=32.2105263157895, Blast_Score=192, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6324924, Length=412, Percent_Identity=32.2815533980583, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320772, Length=442, Percent_Identity=32.1266968325792, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322892, Length=402, Percent_Identity=32.3383084577114, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6324990, Length=450, Percent_Identity=29.5555555555556, Blast_Score=169, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6320717, Length=407, Percent_Identity=28.2555282555283, Blast_Score=153, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6324059, Length=448, Percent_Identity=31.6964285714286, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324553, Length=436, Percent_Identity=28.4403669724771, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=400, Percent_Identity=29, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321629, Length=448, Percent_Identity=27.6785714285714, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6321053, Length=422, Percent_Identity=27.2511848341232, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319543, Length=401, Percent_Identity=27.930174563591, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6320251, Length=403, Percent_Identity=29.7766749379653, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6319542, Length=401, Percent_Identity=27.6807980049875, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6322967, Length=405, Percent_Identity=28.3950617283951, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319608, Length=409, Percent_Identity=24.2053789731051, Blast_Score=109, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6324981, Length=409, Percent_Identity=27.3838630806846, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320364, Length=505, Percent_Identity=23.1683168316832, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50005; Mature: 50005

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00024 HEMOPEXIN ; PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDLPQLKRSLTSNQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLLAYGFAGLILYLVM
CCCHHHHHHHHHCCCCEEEEEECCHHHHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
RALGEILYVNPSTGSFADYATNYIHPLAGYLTMWSNIFQFIVVGISEVVAVSQYLNYWWP
HHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NLPGWVSSVVVIATLTLANLVSTKAYGAIEFYFALIKVLTIILMIIIGVLVIFMGLGNHW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RPVGLSNLWAHGGFFTGGVKGFLFALSIVVGSYQGIELLGITAGEAANPKKAIVASVKSI
CCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
VWRILIFYLGAIFVIVAIFPWNQLATVGSPFVETFSKVGITGAAGIINFVVLTAAMSGTN
HHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
SGIYSASRMLYKLSQEGKVPKIFGKLSSHRVPSVAILTISFGILLGIILNIFLSSFKGGA
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VNLFVLIYSSSVLPGMVPWFVILLSELRFRRANPEIIQNHPFVMPLYPMSNYLAIISLLL
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCHHHHHHHHHHHH
IVVFMFINPDTRASVTVGFVFLMVLTINFIIKFRRKRG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEDLPQLKRSLTSNQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLLAYGFAGLILYLVM
CCCHHHHHHHHHCCCCEEEEEECCHHHHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
RALGEILYVNPSTGSFADYATNYIHPLAGYLTMWSNIFQFIVVGISEVVAVSQYLNYWWP
HHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NLPGWVSSVVVIATLTLANLVSTKAYGAIEFYFALIKVLTIILMIIIGVLVIFMGLGNHW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RPVGLSNLWAHGGFFTGGVKGFLFALSIVVGSYQGIELLGITAGEAANPKKAIVASVKSI
CCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
VWRILIFYLGAIFVIVAIFPWNQLATVGSPFVETFSKVGITGAAGIINFVVLTAAMSGTN
HHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
SGIYSASRMLYKLSQEGKVPKIFGKLSSHRVPSVAILTISFGILLGIILNIFLSSFKGGA
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VNLFVLIYSSSVLPGMVPWFVILLSELRFRRANPEIIQNHPFVMPLYPMSNYLAIISLLL
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCHHHHHHHHHHHH
IVVFMFINPDTRASVTVGFVFLMVLTINFIIKFRRKRG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]