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The map label for this gene is accA [H]

Identifier: 116492630

GI number: 116492630

Start: 866706

End: 867473

Strand: Direct

Name: accA [H]

Synonym: PEPE_0864

Alternate gene names: 116492630

Gene position: 866706-867473 (Clockwise)

Preceding gene: 116492629

Following gene: 116492631

Centisome position: 47.3

GC content: 38.02

Gene sequence:

>768_bases
ATGGCAAAAACAGCATATGAAACAGTGACTGCTGCTCGCAGTAAGGATAAAGTTGCAACTGCTGATTTGATAAATAATAT
TTTCTCGAATTTTACGGAATTCCATGGAGACCGTCAATTAAGTGACGATCCTGCTGTGATTGGTGGAATCGCTCTATTGA
ACGGTACACCAGTAACCGTAATTGGTACCCAAAAAGGTAAAAATACCGCTGAAAATATTGAACGTCATTTTGGAACTGTT
GAACCTGAAGGGTATCGAAAAGCAGTACGTCTGATGCAACAAGCTGAAAAATTTAAACGACCAGTAATTACATTTGTTAA
CACACCAGGGGCTTATCCAGGAATGGATGCTGAGTATCATGGTCAAGGTTCAGCAATTGCTAACAGTTTAATAGTGGGGA
TGGAACTTCGTGTCCCTTATATCAGTATTATTGTTGGTGAAGGTGGTAGCGGAGGTGCATTGGCTCTGGCTACCGGTGAT
ACAGTTTGGATGATGGAAAATAGTATCTATTCAGTTTTATCACCTGAAGGTTATGCTTCAATCGTTTGGAAGGATTCTAA
ACGTGTTATTGAAGCTTCTGAGGCTTTAAAATTAACTCCAGAACATTTACTTGAAGATGGAATTATCGATAAAATTGTTC
CAGAAGTTGTTGATCAAACTAGTACACAAAATTTAAAACAAATGTTAGTTACAGAAGTAAATCGTTTAAGTCAATTTTCA
GCTGATGAACTCGTGCAGCGACGACATGAACGATTTAGTAAATTCTAG

Upstream 100 bases:

>100_bases
TAAAAATGGATTCTTAGATGATATTGTTGAACGACCAAATTTAAAAGAATATTTGAATAATCTTTTAAATTTACATTCAG
ATAAGTAAGTAGGGATAAAA

Downstream 100 bases:

>100_bases
AAGAGGGGTTATGCAGTTGGAAGGAATTCTTAGTGGAAAAACCATTGTCATTATGGGTGTAGCGAATAAGAACAGTATTG
CTTGGGGTTGTACAAAAGCA

Product: acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MAKTAYETVTAARSKDKVATADLINNIFSNFTEFHGDRQLSDDPAVIGGIALLNGTPVTVIGTQKGKNTAENIERHFGTV
EPEGYRKAVRLMQQAEKFKRPVITFVNTPGAYPGMDAEYHGQGSAIANSLIVGMELRVPYISIIVGEGGSGGALALATGD
TVWMMENSIYSVLSPEGYASIVWKDSKRVIEASEALKLTPEHLLEDGIIDKIVPEVVDQTSTQNLKQMLVTEVNRLSQFS
ADELVQRRHERFSKF

Sequences:

>Translated_255_residues
MAKTAYETVTAARSKDKVATADLINNIFSNFTEFHGDRQLSDDPAVIGGIALLNGTPVTVIGTQKGKNTAENIERHFGTV
EPEGYRKAVRLMQQAEKFKRPVITFVNTPGAYPGMDAEYHGQGSAIANSLIVGMELRVPYISIIVGEGGSGGALALATGD
TVWMMENSIYSVLSPEGYASIVWKDSKRVIEASEALKLTPEHLLEDGIIDKIVPEVVDQTSTQNLKQMLVTEVNRLSQFS
ADELVQRRHERFSKF
>Mature_254_residues
AKTAYETVTAARSKDKVATADLINNIFSNFTEFHGDRQLSDDPAVIGGIALLNGTPVTVIGTQKGKNTAENIERHFGTVE
PEGYRKAVRLMQQAEKFKRPVITFVNTPGAYPGMDAEYHGQGSAIANSLIVGMELRVPYISIIVGEGGSGGALALATGDT
VWMMENSIYSVLSPEGYASIVWKDSKRVIEASEALKLTPEHLLEDGIIDKIVPEVVDQTSTQNLKQMLVTEVNRLSQFSA
DELVQRRHERFSKF

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=257, Percent_Identity=45.136186770428, Blast_Score=231, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 27918; Mature: 27787

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTAYETVTAARSKDKVATADLINNIFSNFTEFHGDRQLSDDPAVIGGIALLNGTPVTV
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEECCCCEEE
IGTQKGKNTAENIERHFGTVEPEGYRKAVRLMQQAEKFKRPVITFVNTPGAYPGMDAEYH
EECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
GQGSAIANSLIVGMELRVPYISIIVGEGGSGGALALATGDTVWMMENSIYSVLSPEGYAS
CCCHHHHHHHHEEEEECCCEEEEEEECCCCCCEEEEECCCEEEEECCCHHHHCCCCCCEE
IVWKDSKRVIEASEALKLTPEHLLEDGIIDKIVPEVVDQTSTQNLKQMLVTEVNRLSQFS
EEECCCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
ADELVQRRHERFSKF
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKTAYETVTAARSKDKVATADLINNIFSNFTEFHGDRQLSDDPAVIGGIALLNGTPVTV
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEECCCCEEE
IGTQKGKNTAENIERHFGTVEPEGYRKAVRLMQQAEKFKRPVITFVNTPGAYPGMDAEYH
EECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
GQGSAIANSLIVGMELRVPYISIIVGEGGSGGALALATGDTVWMMENSIYSVLSPEGYAS
CCCHHHHHHHHEEEEECCCEEEEEEECCCCCCEEEEECCCEEEEECCCHHHHCCCCCCEE
IVWKDSKRVIEASEALKLTPEHLLEDGIIDKIVPEVVDQTSTQNLKQMLVTEVNRLSQFS
EEECCCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
ADELVQRRHERFSKF
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]