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The map label for this gene is nadD [H]

Identifier: 116492474

GI number: 116492474

Start: 745908

End: 746552

Strand: Direct

Name: nadD [H]

Synonym: PEPE_0706

Alternate gene names: 116492474

Gene position: 745908-746552 (Clockwise)

Preceding gene: 116492473

Following gene: 116492475

Centisome position: 40.71

GC content: 37.36

Gene sequence:

>645_bases
TTGATAGCAACAAAATCTAAAACAGTTTCTGGAGTACAAGTAGAAGTGGTTGAAGAGCCATTAATACAAAAGAAAGGCAA
GAAAATTGGCATTCTGGGAGGGACGTTTAATCCGCCTCACATTGCTCATTTATTAATTGCTGAACAAGTAGGAAGCCAGT
TGGGACTGGATAAGGTGCTATTTATTCCAGATTTTATTCCACCACATGTTGATGAGAAAAAAACCATTCCTGCTGAGCAC
CGAGTTGAAATGGTCTGCTTAGCTATTCAGGATAACCCACTGTTTGATTTAGATTTAATCGAAATTAATCGTGGTGGCTC
AAGTTATTCGTACGATACGGTTAAAGAATTAAAACAACTACATCCGGAAAATGACTATTATTTTATTATTGGTGGTGACA
TGGCGGACTATTTACCGACTTGGCATCGAATTGACGAATTAGTTAAAATGGTTCAATTTGTGGGTGTTGATCGGCCGAAA
TATCAACGCCAAGAACAATATCCGATTATTTGGGTAGATGTTCCTAAGATGGACATTAGTTCCACCAAAATTAGAAAAAA
CGTTAAGAATGGGTGTTCAATTAGGTATCAAGTGCCCGAAAGTGTCGAAAAGTATATAAAGGAGCACCGTTTATATGAGC
AATAA

Upstream 100 bases:

>100_bases
ACCATTGGACGGGTACTAGTGTTGTTTAAAGTTTCTTCGGAAGCGGATAAACGTGAAATTTCAGATACAGTTAAGAAGAT
ATAGATAAAGGTGATTAATC

Downstream 100 bases:

>100_bases
TGAAGAATTAATTTATCAAAAAAACTACGTGCCTTTTACGCGAGCAGAATTAATCGACGCTGTTTCTAAAAGTATTACCG
GAAGTCGATTCGAACATGTT

Product: nicotinate-nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIATKSKTVSGVQVEVVEEPLIQKKGKKIGILGGTFNPPHIAHLLIAEQVGSQLGLDKVLFIPDFIPPHVDEKKTIPAEH
RVEMVCLAIQDNPLFDLDLIEINRGGSSYSYDTVKELKQLHPENDYYFIIGGDMADYLPTWHRIDELVKMVQFVGVDRPK
YQRQEQYPIIWVDVPKMDISSTKIRKNVKNGCSIRYQVPESVEKYIKEHRLYEQ

Sequences:

>Translated_214_residues
MIATKSKTVSGVQVEVVEEPLIQKKGKKIGILGGTFNPPHIAHLLIAEQVGSQLGLDKVLFIPDFIPPHVDEKKTIPAEH
RVEMVCLAIQDNPLFDLDLIEINRGGSSYSYDTVKELKQLHPENDYYFIIGGDMADYLPTWHRIDELVKMVQFVGVDRPK
YQRQEQYPIIWVDVPKMDISSTKIRKNVKNGCSIRYQVPESVEKYIKEHRLYEQ
>Mature_214_residues
MIATKSKTVSGVQVEVVEEPLIQKKGKKIGILGGTFNPPHIAHLLIAEQVGSQLGLDKVLFIPDFIPPHVDEKKTIPAEH
RVEMVCLAIQDNPLFDLDLIEINRGGSSYSYDTVKELKQLHPENDYYFIIGGDMADYLPTWHRIDELVKMVQFVGVDRPK
YQRQEQYPIIWVDVPKMDISSTKIRKNVKNGCSIRYQVPESVEKYIKEHRLYEQ

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) [H]

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family [H]

Homologues:

Organism=Escherichia coli, GI1786858, Length=208, Percent_Identity=32.6923076923077, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432 [H]

EC number: =2.7.7.18 [H]

Molecular weight: Translated: 24588; Mature: 24588

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATKSKTVSGVQVEVVEEPLIQKKGKKIGILGGTFNPPHIAHLLIAEQVGSQLGLDKVL
CCCCCCCCCCCEEEEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEE
FIPDFIPPHVDEKKTIPAEHRVEMVCLAIQDNPLFDLDLIEINRGGSSYSYDTVKELKQL
ECCCCCCCCCCCCCCCCHHHCEEEEEEEECCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
HPENDYYFIIGGDMADYLPTWHRIDELVKMVQFVGVDRPKYQRQEQYPIIWVDVPKMDIS
CCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEECCCCCCC
STKIRKNVKNGCSIRYQVPESVEKYIKEHRLYEQ
HHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIATKSKTVSGVQVEVVEEPLIQKKGKKIGILGGTFNPPHIAHLLIAEQVGSQLGLDKVL
CCCCCCCCCCCEEEEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEE
FIPDFIPPHVDEKKTIPAEHRVEMVCLAIQDNPLFDLDLIEINRGGSSYSYDTVKELKQL
ECCCCCCCCCCCCCCCCHHHCEEEEEEEECCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
HPENDYYFIIGGDMADYLPTWHRIDELVKMVQFVGVDRPKYQRQEQYPIIWVDVPKMDIS
CCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEECCCCCCC
STKIRKNVKNGCSIRYQVPESVEKYIKEHRLYEQ
HHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]