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The map label for this gene is lytT [H]

Identifier: 116492464

GI number: 116492464

Start: 739293

End: 740024

Strand: Direct

Name: lytT [H]

Synonym: PEPE_0696

Alternate gene names: 116492464

Gene position: 739293-740024 (Clockwise)

Preceding gene: 116492463

Following gene: 116492465

Centisome position: 40.35

GC content: 31.56

Gene sequence:

>732_bases
GTGAAGATATTAATTGTTGATGATGAGCCCCTAGCTCGAAGTGAACTTGATTTTTTATTGAGGAATAATCCGTTAGTAGA
TAGCGTTAGTGAAGCAGAAGGAGTCACTGAAGCTAAACAAAAATTAATGACGGATCAACCGGATCTAATGTTTTTAGATA
TTAGACTTGATGATGGAAATGGGATGTCATTTGCAAAATTCTTGAAAAAGGAAGAAAAACTACGTCCATATATTGTTTTT
GCCACGGCTTACGATCAATATGCTTTAGATGCATTTGACGTTAATGCTACAGATTACATATTAAAACCCTTTGAAAAAGA
TCGTATTGATGAAACGCTTAAACGAGTTGATAGAATTTTAAAAAAGCCAGAGGCATTAGTTAATAGTGACATGTGTAAAA
ATCCGCGACTTTCAGTTACAGTTGATGAAAGAACGATAATTATTAAAAAGAGCGATATTCTTTATTTAGAAGCCCAAAAT
GGGAATGTATTAATTTATACTAAAAATTTACCATTAATCTCAAGCAAACAAACGTTGATTAACCTTGAAAAGCAGTTAGA
TCCAGAACAATTTCTACGAGTACATAGAAGTTTTCTAGTAAATTTAGATATGATTTTGGAGTTTCAACCCAGCTTTAATC
ATACTTATGAATTAACATTAATAAATGGAACCAAGATTACGGTTAGTAGATCATATGTTGCTAAAACTAAAAAAGTGTTA
GGAATTGGATGA

Upstream 100 bases:

>100_bases
TGGGTCTTTATGGTAAAGATGCCGAACTAAAAATAAGCAGTGATCAAAATGGAACCCAGGTGGTAATCCAAATTCCATAT
AAGGAACAGGTGTAAAGATA

Downstream 100 bases:

>100_bases
TCTAATATTTATAAATTGTAGAATAAGTTCATACCTATTCTTAGAAATTCTCAACTCAATCGTTGAGGATTTTTTAATTA
AAAACCAAGGTAACTAACAC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKILIVDDEPLARSELDFLLRNNPLVDSVSEAEGVTEAKQKLMTDQPDLMFLDIRLDDGNGMSFAKFLKKEEKLRPYIVF
ATAYDQYALDAFDVNATDYILKPFEKDRIDETLKRVDRILKKPEALVNSDMCKNPRLSVTVDERTIIIKKSDILYLEAQN
GNVLIYTKNLPLISSKQTLINLEKQLDPEQFLRVHRSFLVNLDMILEFQPSFNHTYELTLINGTKITVSRSYVAKTKKVL
GIG

Sequences:

>Translated_243_residues
MKILIVDDEPLARSELDFLLRNNPLVDSVSEAEGVTEAKQKLMTDQPDLMFLDIRLDDGNGMSFAKFLKKEEKLRPYIVF
ATAYDQYALDAFDVNATDYILKPFEKDRIDETLKRVDRILKKPEALVNSDMCKNPRLSVTVDERTIIIKKSDILYLEAQN
GNVLIYTKNLPLISSKQTLINLEKQLDPEQFLRVHRSFLVNLDMILEFQPSFNHTYELTLINGTKITVSRSYVAKTKKVL
GIG
>Mature_243_residues
MKILIVDDEPLARSELDFLLRNNPLVDSVSEAEGVTEAKQKLMTDQPDLMFLDIRLDDGNGMSFAKFLKKEEKLRPYIVF
ATAYDQYALDAFDVNATDYILKPFEKDRIDETLKRVDRILKKPEALVNSDMCKNPRLSVTVDERTIIIKKSDILYLEAQN
GNVLIYTKNLPLISSKQTLINLEKQLDPEQFLRVHRSFLVNLDMILEFQPSFNHTYELTLINGTKITVSRSYVAKTKKVL
GIG

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=249, Percent_Identity=31.7269076305221, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI87082052, Length=243, Percent_Identity=32.5102880658436, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27921; Mature: 27921

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIVDDEPLARSELDFLLRNNPLVDSVSEAEGVTEAKQKLMTDQPDLMFLDIRLDDGN
CEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHCCCCCEEEEEEEEECCC
GMSFAKFLKKEEKLRPYIVFATAYDQYALDAFDVNATDYILKPFEKDRIDETLKRVDRIL
CCHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCHHEECCCCHHHHHHHHHHHHHHH
KKPEALVNSDMCKNPRLSVTVDERTIIIKKSDILYLEAQNGNVLIYTKNLPLISSKQTLI
HCCHHHHCCCCCCCCCEEEEECCEEEEEEECCEEEEEECCCCEEEEECCCCCCCCCHHHE
NLEKQLDPEQFLRVHRSFLVNLDMILEFQPSFNHTYELTLINGTKITVSRSYVAKTKKVL
EHHHCCCHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEEEECCEEEEEHHHHHHHHHHC
GIG
CCC
>Mature Secondary Structure
MKILIVDDEPLARSELDFLLRNNPLVDSVSEAEGVTEAKQKLMTDQPDLMFLDIRLDDGN
CEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHCCCCCEEEEEEEEECCC
GMSFAKFLKKEEKLRPYIVFATAYDQYALDAFDVNATDYILKPFEKDRIDETLKRVDRIL
CCHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCHHEECCCCHHHHHHHHHHHHHHH
KKPEALVNSDMCKNPRLSVTVDERTIIIKKSDILYLEAQNGNVLIYTKNLPLISSKQTLI
HCCHHHHCCCCCCCCCEEEEECCEEEEEEECCEEEEEECCCCEEEEECCCCCCCCCHHHE
NLEKQLDPEQFLRVHRSFLVNLDMILEFQPSFNHTYELTLINGTKITVSRSYVAKTKKVL
EHHHCCCHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEEEECCEEEEEHHHHHHHHHHC
GIG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]