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The map label for this gene is argS

Identifier: 116492437

GI number: 116492437

Start: 707778

End: 709466

Strand: Direct

Name: argS

Synonym: PEPE_0669

Alternate gene names: 116492437

Gene position: 707778-709466 (Clockwise)

Preceding gene: 116492436

Following gene: 116492438

Centisome position: 38.63

GC content: 37.06

Gene sequence:

>1689_bases
ATGGATTATAAGAAGAAAGTTGCTGCTGCTTTAGCACCTGCACTAAACGAGTATCTTACTGATACAGAAATTTACGAAAA
AATTGAAATTCCTAAGGAAAGTAAGATGGGTGATTACGCCTTTCCAACCTTTACCTTAGCTAAGGTATTGCGCAAAGCAC
CACAAATGATTGCGAGTGAATTGGTTGAAAAGATTGACCAAGATCAATTTGAAAAGGTTGAAGTTGCTGGACCATATATT
AATTTCTTCCTTGACAAGACTGCTTTTGGAGCAGAAGTTTTAGGTACAGTTTTAAGTCAAAAAGCTGAATATGGTCAAAA
TGACGATGGTAATCAAGGAAATGTTCCAATTGATATGTCATCTCCTAACATTGCTAAACCAATCTCAATGGGACATTTAC
GGTCAACAGTAATTGGTAACTCATTGTCATTAATTATGAGTAAAAATGGGTACAATCCAATTAAGATTAACCATCTTGGA
GACTGGGGAACTCAATTTGGTAAGTTGATCACAGCTTACAAGCTTTGGGGTAGCGAAGAGGAAGTTAAAGCAGATCCAAT
TAACAAGTTACTTGAATACTATGTTCGTTTCCATAAAGAAGACCAAGAAAAACCAGAACTAGACGACATTGCTCGAGACT
GGTTTAAGAAGCTTGAAGATGGTGATGAAGAAGCCATGAACCTTTGGCAATGGTTCCGTGAAGAATCGCTAAAATCGTTT
AAGCAAATTTATGACAAACTAGGAATTACATTTGATTCATATAAGGGTGAAGCTTTCTACAACGATAAGATGGATGAAAT
TGTCCAAATTCTTGAAGACAAGGGTCTGCTTAAAGAAAGCCAAGGAGCTCAAGTAGTTGACTTAGAGAAGTACAATTTAA
ATCCAGCATTAATTAAGAAGACGGATGGAGCAACCCTTTACATTACTCGTGATTTAGCTGCTGCTTTGTATCGTTACCGG
ACTTATGATTTTAACCAATCATTGTATGTTGTTGGTGCTGAACAAACTAACCATTTCAAGCAACTAAAGGCTGTTTTAAA
GGAAATGGGCTTCGATTGGTCGGATGATGTACATCATATTCCATTTGGTTTAATTACCTTGAATGGTAAAAAACTTTCAA
CTCGTTCAGGTCGAGTTGTATTGCTGGATGAAGTTTTAAATGATGCGGTTAGTTTGGCTAAAAAACAAATTAACGATAAG
AACCCGGATTTAGCCAATGCAGATACTGTAGCTAAAGAAGTCGGGGTCGGTGCGGTAATCTTCCATGATCTTAAGAATGA
AAGAACTAATTCATTTGATTTCAATCTAGAAGATGTTGTTCGTTTTGAAGGGGAAACAGGACCTTACGTTCAATATAGTC
GAGCTCGTGCTGAAAGTATTTTGAGAAAAGCTGGCGATGTCGAAGAATTCGCTCAATTAAATATTACGGATCCTAAAGCT
TGGGATACTTTGAAAGCTCTTCAAGATTTCCCTAATATTGTGAAGCGAGCAGCTGCTCAATATGAACCTTCGGTAATCGC
TAAGTATGCCCTAGGTTTAGCAAAGGCCTTCAACAAATATTATGCTAACTCTAAAATTTTGGCTGACGATGAAGAAAAAA
CAGCTCGTTTAGCATTGGTTAAGAGTGTAAGTATTGTACTAGAAGAATCCTTACGCCTATTAGGAGTAAAAGCTCCTGAC
GAAATGTAA

Upstream 100 bases:

>100_bases
TGGATTATTTAATCAATTAGAGTGGTACCGCGGGAAATCTCGTCTCTTACATTTTTACAAATGTAAGGGGCGTTTTTTAT
TTCGCAGAATGGAGGAAAAA

Downstream 100 bases:

>100_bases
TAACTGAACTAATTTTAAAATAAAAAAGTGAATATTTCGTAATTTATAAATGAGGACCGCGTTCAAAATGATGTTTTTTG
GACCGGTTTTTTATTTTCTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MDYKKKVAAALAPALNEYLTDTEIYEKIEIPKESKMGDYAFPTFTLAKVLRKAPQMIASELVEKIDQDQFEKVEVAGPYI
NFFLDKTAFGAEVLGTVLSQKAEYGQNDDGNQGNVPIDMSSPNIAKPISMGHLRSTVIGNSLSLIMSKNGYNPIKINHLG
DWGTQFGKLITAYKLWGSEEEVKADPINKLLEYYVRFHKEDQEKPELDDIARDWFKKLEDGDEEAMNLWQWFREESLKSF
KQIYDKLGITFDSYKGEAFYNDKMDEIVQILEDKGLLKESQGAQVVDLEKYNLNPALIKKTDGATLYITRDLAAALYRYR
TYDFNQSLYVVGAEQTNHFKQLKAVLKEMGFDWSDDVHHIPFGLITLNGKKLSTRSGRVVLLDEVLNDAVSLAKKQINDK
NPDLANADTVAKEVGVGAVIFHDLKNERTNSFDFNLEDVVRFEGETGPYVQYSRARAESILRKAGDVEEFAQLNITDPKA
WDTLKALQDFPNIVKRAAAQYEPSVIAKYALGLAKAFNKYYANSKILADDEEKTARLALVKSVSIVLEESLRLLGVKAPD
EM

Sequences:

>Translated_562_residues
MDYKKKVAAALAPALNEYLTDTEIYEKIEIPKESKMGDYAFPTFTLAKVLRKAPQMIASELVEKIDQDQFEKVEVAGPYI
NFFLDKTAFGAEVLGTVLSQKAEYGQNDDGNQGNVPIDMSSPNIAKPISMGHLRSTVIGNSLSLIMSKNGYNPIKINHLG
DWGTQFGKLITAYKLWGSEEEVKADPINKLLEYYVRFHKEDQEKPELDDIARDWFKKLEDGDEEAMNLWQWFREESLKSF
KQIYDKLGITFDSYKGEAFYNDKMDEIVQILEDKGLLKESQGAQVVDLEKYNLNPALIKKTDGATLYITRDLAAALYRYR
TYDFNQSLYVVGAEQTNHFKQLKAVLKEMGFDWSDDVHHIPFGLITLNGKKLSTRSGRVVLLDEVLNDAVSLAKKQINDK
NPDLANADTVAKEVGVGAVIFHDLKNERTNSFDFNLEDVVRFEGETGPYVQYSRARAESILRKAGDVEEFAQLNITDPKA
WDTLKALQDFPNIVKRAAAQYEPSVIAKYALGLAKAFNKYYANSKILADDEEKTARLALVKSVSIVLEESLRLLGVKAPD
EM
>Mature_562_residues
MDYKKKVAAALAPALNEYLTDTEIYEKIEIPKESKMGDYAFPTFTLAKVLRKAPQMIASELVEKIDQDQFEKVEVAGPYI
NFFLDKTAFGAEVLGTVLSQKAEYGQNDDGNQGNVPIDMSSPNIAKPISMGHLRSTVIGNSLSLIMSKNGYNPIKINHLG
DWGTQFGKLITAYKLWGSEEEVKADPINKLLEYYVRFHKEDQEKPELDDIARDWFKKLEDGDEEAMNLWQWFREESLKSF
KQIYDKLGITFDSYKGEAFYNDKMDEIVQILEDKGLLKESQGAQVVDLEKYNLNPALIKKTDGATLYITRDLAAALYRYR
TYDFNQSLYVVGAEQTNHFKQLKAVLKEMGFDWSDDVHHIPFGLITLNGKKLSTRSGRVVLLDEVLNDAVSLAKKQINDK
NPDLANADTVAKEVGVGAVIFHDLKNERTNSFDFNLEDVVRFEGETGPYVQYSRARAESILRKAGDVEEFAQLNITDPKA
WDTLKALQDFPNIVKRAAAQYEPSVIAKYALGLAKAFNKYYANSKILADDEEKTARLALVKSVSIVLEESLRLLGVKAPD
EM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=581, Percent_Identity=32.013769363167, Blast_Score=310, Evalue=3e-84,
Organism=Homo sapiens, GI15149476, Length=562, Percent_Identity=28.8256227758007, Blast_Score=214, Evalue=2e-55,
Organism=Escherichia coli, GI1788184, Length=579, Percent_Identity=32.9879101899827, Blast_Score=261, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71985061, Length=561, Percent_Identity=28.1639928698752, Blast_Score=182, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI71985068, Length=526, Percent_Identity=28.5171102661597, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17532153, Length=491, Percent_Identity=27.6985743380855, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320548, Length=561, Percent_Identity=35.4723707664884, Blast_Score=356, Evalue=6e-99,
Organism=Saccharomyces cerevisiae, GI6321883, Length=561, Percent_Identity=33.3333333333333, Blast_Score=327, Evalue=3e-90,
Organism=Drosophila melanogaster, GI28571570, Length=466, Percent_Identity=31.9742489270386, Blast_Score=222, Evalue=7e-58,
Organism=Drosophila melanogaster, GI18859963, Length=589, Percent_Identity=28.5229202037351, Blast_Score=204, Evalue=1e-52,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_PEDPA (Q03GE2)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804172.1
- ProteinModelPortal:   Q03GE2
- SMR:   Q03GE2
- STRING:   Q03GE2
- GeneID:   4418134
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0669
- NMPDR:   fig|278197.10.peg.594
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   AYKKWGN
- PhylomeDB:   Q03GE2
- ProtClustDB:   PRK01611
- BioCyc:   PPEN278197:PEPE_0669-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63512; Mature: 63512

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKKKVAAALAPALNEYLTDTEIYEKIEIPKESKMGDYAFPTFTLAKVLRKAPQMIASE
CCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LVEKIDQDQFEKVEVAGPYINFFLDKTAFGAEVLGTVLSQKAEYGQNDDGNQGNVPIDMS
HHHHHCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
SPNIAKPISMGHLRSTVIGNSLSLIMSKNGYNPIKINHLGDWGTQFGKLITAYKLWGSEE
CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCC
EVKADPINKLLEYYVRFHKEDQEKPELDDIARDWFKKLEDGDEEAMNLWQWFREESLKSF
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KQIYDKLGITFDSYKGEAFYNDKMDEIVQILEDKGLLKESQGAQVVDLEKYNLNPALIKK
HHHHHHHCCEEECCCCCEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHEEEE
TDGATLYITRDLAAALYRYRTYDFNQSLYVVGAEQTNHFKQLKAVLKEMGFDWSDDVHHI
CCCCEEEEEHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCC
PFGLITLNGKKLSTRSGRVVLLDEVLNDAVSLAKKQINDKNPDLANADTVAKEVGVGAVI
CEEEEEECCCEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHE
FHDLKNERTNSFDFNLEDVVRFEGETGPYVQYSRARAESILRKAGDVEEFAQLNITDPKA
EEHHHCCCCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHH
WDTLKALQDFPNIVKRAAAQYEPSVIAKYALGLAKAFNKYYANSKILADDEEKTARLALV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHH
KSVSIVLEESLRLLGVKAPDEM
HHHHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MDYKKKVAAALAPALNEYLTDTEIYEKIEIPKESKMGDYAFPTFTLAKVLRKAPQMIASE
CCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LVEKIDQDQFEKVEVAGPYINFFLDKTAFGAEVLGTVLSQKAEYGQNDDGNQGNVPIDMS
HHHHHCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
SPNIAKPISMGHLRSTVIGNSLSLIMSKNGYNPIKINHLGDWGTQFGKLITAYKLWGSEE
CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCC
EVKADPINKLLEYYVRFHKEDQEKPELDDIARDWFKKLEDGDEEAMNLWQWFREESLKSF
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KQIYDKLGITFDSYKGEAFYNDKMDEIVQILEDKGLLKESQGAQVVDLEKYNLNPALIKK
HHHHHHHCCEEECCCCCEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHEEEE
TDGATLYITRDLAAALYRYRTYDFNQSLYVVGAEQTNHFKQLKAVLKEMGFDWSDDVHHI
CCCCEEEEEHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCC
PFGLITLNGKKLSTRSGRVVLLDEVLNDAVSLAKKQINDKNPDLANADTVAKEVGVGAVI
CEEEEEECCCEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHE
FHDLKNERTNSFDFNLEDVVRFEGETGPYVQYSRARAESILRKAGDVEEFAQLNITDPKA
EEHHHCCCCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHH
WDTLKALQDFPNIVKRAAAQYEPSVIAKYALGLAKAFNKYYANSKILADDEEKTARLALV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHH
KSVSIVLEESLRLLGVKAPDEM
HHHHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA