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The map label for this gene is mnaA [H]

Identifier: 116492391

GI number: 116492391

Start: 652082

End: 653194

Strand: Direct

Name: mnaA [H]

Synonym: PEPE_0597

Alternate gene names: 116492391

Gene position: 652082-653194 (Clockwise)

Preceding gene: 116492389

Following gene: 116492393

Centisome position: 35.59

GC content: 44.29

Gene sequence:

>1113_bases
ATGAAGCAGATTAAAGTAATGAGTATCTTTGGGACACGACCAGAAGCCATTAAGATGGCACCAGTGGTCAAAGCCATGAA
AAATGACGACCGGTTTGAACCCATCACGGTGGTGACTGGCCAGCACCGTGAAATGCTCGACCAAGTTTTACAAATTTTCC
AGATTAAACCAGATTATGATTTGAACATCATGGAAAAGAGTCAAACTTTGAGTAGCATTACAAGTAAGGTCTTATCCGGC
ATGGACGAAATTTTAAATCACGATCGCCCGGATTTAATTTTGGTACATGGGGATACAACGACGACTTTCTCGGCGGGCTT
GAGTGCTTTTTACCACCAAATCCCTGTTGGACACGTGGAGGCTGGTTTACGGACTTGGAATAAGTATTCCCCATTTCCAG
AAGAAATGAATCGCCAAATGACCGATGTGCTAACAGATCTTTATTTTGCTCCAACCACAACCAGTGAAGCAAACTTGCTT
CAGGAAAATCATCCACAAAAACAAATTTTTGTGACTGGTAATACGGCGATTGATGCCTTACATGATACGGTCCAAAAAGA
TTACCAAAATGAGGTTCTTGATGAAATCAAGGCCGAACATCGGATTATCTTAGTTACCATGCATCGCCGTGAAAACCAAG
GCGTTCCGATGCAACGAGTGTTTAAAGCCATCCGCCAAGTGGTCGACGAAACTCCTGACGTGGAAGTGATTTTCCCTGTC
CATCTCAACCCTAAGGTTCAACAGATGGCAGAAGAGGAATTGGGCAATGACGCTCGAATTAAATTAATTGCTCCTTTAGA
TGTACTGGACTTCCATAACATTGCTGCTCGGAGTTATTTGATTATGACTGATTCCGGTGGAGTCCAAGAAGAAGCCCCAT
CCCTCGGCAAACCAGTCCTCGTGCTCCGCGATACGACAGAACGTCCCGAAGGGGTTGCTGCCGGAACTTTGAAGTTAGTC
GGTACCGATCCAATAGAGGTTAAAAAACAAATGACCTTGTTGTTGAATGATGCGGAGGCTTACAACCAAATGGCTCAAGC
TAAGAATCCGTATGGAGACGGGACAGCGTCGAAACAAATTCTAGACGCCATTGCTAAATGGCAAAATCAGTAA

Upstream 100 bases:

>100_bases
CATTCATACTGGGAAAACCTCCTTATTTTTTTACTATCCTAGCATATTTTATGCAGGAATGCTGATATAATATTCTTAGA
AGTTGAAGGGTGGCTATAAA

Downstream 100 bases:

>100_bases
TCATTGTATTAGTTTTCGATATAATAAAGGAGCTGTGACTAAGCTACGATAACTTGTCGGTTATCTAGCAGCTGTCACAG
CTCCCTTTATATTATTAATA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKQIKVMSIFGTRPEAIKMAPVVKAMKNDDRFEPITVVTGQHREMLDQVLQIFQIKPDYDLNIMEKSQTLSSITSKVLSG
MDEILNHDRPDLILVHGDTTTTFSAGLSAFYHQIPVGHVEAGLRTWNKYSPFPEEMNRQMTDVLTDLYFAPTTTSEANLL
QENHPQKQIFVTGNTAIDALHDTVQKDYQNEVLDEIKAEHRIILVTMHRRENQGVPMQRVFKAIRQVVDETPDVEVIFPV
HLNPKVQQMAEEELGNDARIKLIAPLDVLDFHNIAARSYLIMTDSGGVQEEAPSLGKPVLVLRDTTERPEGVAAGTLKLV
GTDPIEVKKQMTLLLNDAEAYNQMAQAKNPYGDGTASKQILDAIAKWQNQ

Sequences:

>Translated_370_residues
MKQIKVMSIFGTRPEAIKMAPVVKAMKNDDRFEPITVVTGQHREMLDQVLQIFQIKPDYDLNIMEKSQTLSSITSKVLSG
MDEILNHDRPDLILVHGDTTTTFSAGLSAFYHQIPVGHVEAGLRTWNKYSPFPEEMNRQMTDVLTDLYFAPTTTSEANLL
QENHPQKQIFVTGNTAIDALHDTVQKDYQNEVLDEIKAEHRIILVTMHRRENQGVPMQRVFKAIRQVVDETPDVEVIFPV
HLNPKVQQMAEEELGNDARIKLIAPLDVLDFHNIAARSYLIMTDSGGVQEEAPSLGKPVLVLRDTTERPEGVAAGTLKLV
GTDPIEVKKQMTLLLNDAEAYNQMAQAKNPYGDGTASKQILDAIAKWQNQ
>Mature_370_residues
MKQIKVMSIFGTRPEAIKMAPVVKAMKNDDRFEPITVVTGQHREMLDQVLQIFQIKPDYDLNIMEKSQTLSSITSKVLSG
MDEILNHDRPDLILVHGDTTTTFSAGLSAFYHQIPVGHVEAGLRTWNKYSPFPEEMNRQMTDVLTDLYFAPTTTSEANLL
QENHPQKQIFVTGNTAIDALHDTVQKDYQNEVLDEIKAEHRIILVTMHRRENQGVPMQRVFKAIRQVVDETPDVEVIFPV
HLNPKVQQMAEEELGNDARIKLIAPLDVLDFHNIAARSYLIMTDSGGVQEEAPSLGKPVLVLRDTTERPEGVAAGTLKLV
GTDPIEVKKQMTLLLNDAEAYNQMAQAKNPYGDGTASKQILDAIAKWQNQ

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=371, Percent_Identity=50.9433962264151, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41579; Mature: 41579

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIKVMSIFGTRPEAIKMAPVVKAMKNDDRFEPITVVTGQHREMLDQVLQIFQIKPDYD
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCC
LNIMEKSQTLSSITSKVLSGMDEILNHDRPDLILVHGDTTTTFSAGLSAFYHQIPVGHVE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHH
AGLRTWNKYSPFPEEMNRQMTDVLTDLYFAPTTTSEANLLQENHPQKQIFVTGNTAIDAL
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEECCHHHHHH
HDTVQKDYQNEVLDEIKAEHRIILVTMHRRENQGVPMQRVFKAIRQVVDETPDVEVIFPV
HHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEE
HLNPKVQQMAEEELGNDARIKLIAPLDVLDFHNIAARSYLIMTDSGGVQEEAPSLGKPVL
CCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCEE
VLRDTTERPEGVAAGTLKLVGTDPIEVKKQMTLLLNDAEAYNQMAQAKNPYGDGTASKQI
EEECCCCCCCCCEECEEEEECCCHHHHHHHHHHEECCHHHHHHHHHCCCCCCCCCHHHHH
LDAIAKWQNQ
HHHHHHHCCC
>Mature Secondary Structure
MKQIKVMSIFGTRPEAIKMAPVVKAMKNDDRFEPITVVTGQHREMLDQVLQIFQIKPDYD
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCC
LNIMEKSQTLSSITSKVLSGMDEILNHDRPDLILVHGDTTTTFSAGLSAFYHQIPVGHVE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHH
AGLRTWNKYSPFPEEMNRQMTDVLTDLYFAPTTTSEANLLQENHPQKQIFVTGNTAIDAL
HHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEECCHHHHHH
HDTVQKDYQNEVLDEIKAEHRIILVTMHRRENQGVPMQRVFKAIRQVVDETPDVEVIFPV
HHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEE
HLNPKVQQMAEEELGNDARIKLIAPLDVLDFHNIAARSYLIMTDSGGVQEEAPSLGKPVL
CCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCEE
VLRDTTERPEGVAAGTLKLVGTDPIEVKKQMTLLLNDAEAYNQMAQAKNPYGDGTASKQI
EEECCCCCCCCCEECEEEEECCCHHHHHHHHHHEECCHHHHHHHHHCCCCCCCCCHHHHH
LDAIAKWQNQ
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]