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The map label for this gene is yfnA [H]

Identifier: 116492185

GI number: 116492185

Start: 430034

End: 431422

Strand: Reverse

Name: yfnA [H]

Synonym: PEPE_0382

Alternate gene names: 116492185

Gene position: 431422-430034 (Counterclockwise)

Preceding gene: 116492187

Following gene: 116492183

Centisome position: 23.54

GC content: 40.82

Gene sequence:

>1389_bases
ATGAAAATAATAGATAAAATTTTGAGAAAAGAATCATTAGATAATTACTTAAAGACTGACTCAAAATTCGAAAAAACCAT
TGGTCCAAAAGACTTACTGGCGCTCGGAATTGGTGCAGTAATTGGAACTGGAATTTTCATCCTTCCTGGTACCGTTGCAG
CACTGAAGGCTGGACCATCGATTACAATTTCTTTCGTGATTGCTGCAATTGTATGCGCGCTAGCCGGCATGTGCTATGCC
GAATTTGCAGCCTCTATTCCAGTTGCTGGGAGTGCCTATTCGTATGGAACCATCATTTACGGTGAACTTCCCGGTTGGGT
GCTAGGTTGGGCCTTAATTTTGGAATATGTCTTAGCAGTAGCGGCCGTTTCCACTGGATGGTCCGCTTATTTTGGTTCTC
TCCTGGGTGGTTTTGGGATACACATCCCTACTGCCATTTCTGGATCATTTAATCCAAGTCATGGAACTTACATTAATTTA
TTCGCAATTATTATCGTCTTGCTAATCGGATTTTTACTTAATCGAGGCTTCCAGTCGTCCATTCGGATCAATAACTTTAT
GGTCTTTGTTAAAATTGCTATCATTCTAATTTTTATTTTAGTCGGAATCTTTTATGTTAAACCTACTAATTGGAAACCTT
ATTTTCCATTTGGCGTGCACGGTACTTTAGCCGGTGCCTCAACGGTCTTTTTTGCTTATTTAGGTTTTGATACAGTTTCT
GCATCAGCAGCAGAAGTTAAAAATCCTTCGAAAACGATGCCCATTGGCATTATCGGAACTTTAATTATTGCCACCATCTT
CTATGTGGCCGTTTCTTTGGTTCTTACGGGGATGGTTCCTTACACTAAGCTCAATGTTGCCAATCCCGTTGCCCTAGCTT
TACAGTTAGTCCATCAAAATTGGGTAGCCGGATTACTTTCATTGGGCGCTTTAGCCGGAATGACTACCATGATGATTTCT
ATGATTTATGGAAGTTCCCGTCTGGTATATGCTACAGGACGCGATGGTTTGTTGCCTAAGGTCTTAGGAAACCTAGTGGG
TGAACATCATTCGCCACGCAATGCCATGGTGGTAGTTACCATTTTTATCGCCTTTCTAGGAGGCTTCGTTCCTTTAGATC
AATTAACTAACTTAGTCAATATGGGGACTTTACTAGCATTCGCTTTGGTATCCTTGGGAATTATTCCTCTGCGTCATCGC
CAAGATATTCCTAATACGGGCTTTAAAGTACCCGGATATCCATTTATCCCCATCATTTCAGCCTTGGCTTGTATCTATTT
AATTACCACACTTTCGGTGGAAACCTGGATTGGTTCTGCCATCTGGTTTGGAATTGGATTAATTATCTACTTTAGTTATG
GAATTCATCATAGTAAACTGGCCCAATAA

Upstream 100 bases:

>100_bases
TTTAATTTAATCAAATTTACATTTTTAATAAAAGAAATCCGATTGACGTAGTGAAACTGATTCAGTATTATTAGAAAGAT
ATTAGAAAAGGAAGTGTGTT

Downstream 100 bases:

>100_bases
AAAAAGAGTTGTGATAAAGGCAAATGTCTTTAATCACAACTCTTTTAATTTATTTCATACTAATTTGGAAGTTTATTAAG
CACATATAGCATTAGTGCGA

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MKIIDKILRKESLDNYLKTDSKFEKTIGPKDLLALGIGAVIGTGIFILPGTVAALKAGPSITISFVIAAIVCALAGMCYA
EFAASIPVAGSAYSYGTIIYGELPGWVLGWALILEYVLAVAAVSTGWSAYFGSLLGGFGIHIPTAISGSFNPSHGTYINL
FAIIIVLLIGFLLNRGFQSSIRINNFMVFVKIAIILIFILVGIFYVKPTNWKPYFPFGVHGTLAGASTVFFAYLGFDTVS
ASAAEVKNPSKTMPIGIIGTLIIATIFYVAVSLVLTGMVPYTKLNVANPVALALQLVHQNWVAGLLSLGALAGMTTMMIS
MIYGSSRLVYATGRDGLLPKVLGNLVGEHHSPRNAMVVVTIFIAFLGGFVPLDQLTNLVNMGTLLAFALVSLGIIPLRHR
QDIPNTGFKVPGYPFIPIISALACIYLITTLSVETWIGSAIWFGIGLIIYFSYGIHHSKLAQ

Sequences:

>Translated_462_residues
MKIIDKILRKESLDNYLKTDSKFEKTIGPKDLLALGIGAVIGTGIFILPGTVAALKAGPSITISFVIAAIVCALAGMCYA
EFAASIPVAGSAYSYGTIIYGELPGWVLGWALILEYVLAVAAVSTGWSAYFGSLLGGFGIHIPTAISGSFNPSHGTYINL
FAIIIVLLIGFLLNRGFQSSIRINNFMVFVKIAIILIFILVGIFYVKPTNWKPYFPFGVHGTLAGASTVFFAYLGFDTVS
ASAAEVKNPSKTMPIGIIGTLIIATIFYVAVSLVLTGMVPYTKLNVANPVALALQLVHQNWVAGLLSLGALAGMTTMMIS
MIYGSSRLVYATGRDGLLPKVLGNLVGEHHSPRNAMVVVTIFIAFLGGFVPLDQLTNLVNMGTLLAFALVSLGIIPLRHR
QDIPNTGFKVPGYPFIPIISALACIYLITTLSVETWIGSAIWFGIGLIIYFSYGIHHSKLAQ
>Mature_462_residues
MKIIDKILRKESLDNYLKTDSKFEKTIGPKDLLALGIGAVIGTGIFILPGTVAALKAGPSITISFVIAAIVCALAGMCYA
EFAASIPVAGSAYSYGTIIYGELPGWVLGWALILEYVLAVAAVSTGWSAYFGSLLGGFGIHIPTAISGSFNPSHGTYINL
FAIIIVLLIGFLLNRGFQSSIRINNFMVFVKIAIILIFILVGIFYVKPTNWKPYFPFGVHGTLAGASTVFFAYLGFDTVS
ASAAEVKNPSKTMPIGIIGTLIIATIFYVAVSLVLTGMVPYTKLNVANPVALALQLVHQNWVAGLLSLGALAGMTTMMIS
MIYGSSRLVYATGRDGLLPKVLGNLVGEHHSPRNAMVVVTIFIAFLGGFVPLDQLTNLVNMGTLLAFALVSLGIIPLRHR
QDIPNTGFKVPGYPFIPIISALACIYLITTLSVETWIGSAIWFGIGLIIYFSYGIHHSKLAQ

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=434, Percent_Identity=31.3364055299539, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI114326550, Length=434, Percent_Identity=31.3364055299539, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI258645169, Length=438, Percent_Identity=32.1917808219178, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI4507047, Length=443, Percent_Identity=33.4085778781038, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI258614005, Length=438, Percent_Identity=32.1917808219178, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI258614003, Length=438, Percent_Identity=32.1917808219178, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI181337167, Length=417, Percent_Identity=31.6546762589928, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI110347453, Length=405, Percent_Identity=31.8518518518519, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI7657683, Length=385, Percent_Identity=26.7532467532467, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI187423910, Length=486, Percent_Identity=23.2510288065844, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI7657591, Length=486, Percent_Identity=23.2510288065844, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI71979932, Length=458, Percent_Identity=22.9257641921397, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI186910308, Length=455, Percent_Identity=23.5164835164835, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI186910306, Length=455, Percent_Identity=23.5164835164835, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI186910304, Length=455, Percent_Identity=23.5164835164835, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI115648063, Length=452, Percent_Identity=21.9026548672566, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI115648022, Length=452, Percent_Identity=21.9026548672566, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI33286428, Length=406, Percent_Identity=24.6305418719212, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082250, Length=408, Percent_Identity=26.9607843137255, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI87081708, Length=479, Percent_Identity=21.0855949895616, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788480, Length=489, Percent_Identity=22.9038854805726, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786602, Length=421, Percent_Identity=22.5653206650831, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786302, Length=427, Percent_Identity=22.0140515222482, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082023, Length=445, Percent_Identity=24.0449438202247, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081915, Length=426, Percent_Identity=20.6572769953052, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790653, Length=391, Percent_Identity=23.5294117647059, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081869, Length=444, Percent_Identity=21.6216216216216, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786789, Length=416, Percent_Identity=22.1153846153846, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786694, Length=392, Percent_Identity=24.234693877551, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367353, Length=332, Percent_Identity=24.0963855421687, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789017, Length=348, Percent_Identity=22.4137931034483, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=407, Percent_Identity=32.6781326781327, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17531343, Length=408, Percent_Identity=33.8235294117647, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17533459, Length=415, Percent_Identity=31.8072289156626, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI32566695, Length=455, Percent_Identity=24.3956043956044, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193208714, Length=455, Percent_Identity=24.3956043956044, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71982608, Length=428, Percent_Identity=26.6355140186916, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982612, Length=428, Percent_Identity=26.6355140186916, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537453, Length=398, Percent_Identity=22.1105527638191, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71995388, Length=363, Percent_Identity=25.8953168044077, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71995382, Length=362, Percent_Identity=25.9668508287293, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71993915, Length=356, Percent_Identity=26.123595505618, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221512776, Length=412, Percent_Identity=33.7378640776699, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI24666159, Length=412, Percent_Identity=33.7378640776699, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI24667468, Length=415, Percent_Identity=34.4578313253012, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24668806, Length=413, Percent_Identity=33.8983050847458, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI21356285, Length=413, Percent_Identity=33.8983050847458, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24668802, Length=413, Percent_Identity=33.8983050847458, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI281366235, Length=407, Percent_Identity=36.1179361179361, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI116007820, Length=407, Percent_Identity=36.1179361179361, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI116007818, Length=397, Percent_Identity=36.0201511335013, Blast_Score=208, Evalue=7e-54,
Organism=Drosophila melanogaster, GI85725152, Length=397, Percent_Identity=36.0201511335013, Blast_Score=208, Evalue=7e-54,
Organism=Drosophila melanogaster, GI161077963, Length=402, Percent_Identity=33.5820895522388, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI21357367, Length=378, Percent_Identity=21.6931216931217, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI221331183, Length=431, Percent_Identity=22.969837587007, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17647653, Length=431, Percent_Identity=22.969837587007, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24664379, Length=431, Percent_Identity=22.969837587007, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49339; Mature: 49339

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]