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The map label for this gene is pepX

Identifier: 116492183

GI number: 116492183

Start: 425950

End: 428388

Strand: Reverse

Name: pepX

Synonym: PEPE_0380

Alternate gene names: 116492183

Gene position: 428388-425950 (Counterclockwise)

Preceding gene: 116492185

Following gene: 116492182

Centisome position: 23.38

GC content: 39.44

Gene sequence:

>2439_bases
ATGAAAAACAATCAATTCGGTCGAATACGACTGGATCGCACTACTGAACTTGAAGAATTAAAAAACATTCATTTTATTGA
TGCTGATTTATTAGCTGATCCGAAAGCCCAGTTAAAAGATTTTCTAAAACGTTCTTGCCTCGTAAGTAATAGCGAAGCAA
CTTTCCAACAAAAGTTAAGCAATCTACTCGCAACCCCTGATCAAACTATGGCGGCTTTTTTCGAAAGTGATCAACCACTA
ACTTTAGAAATTTTTATCTTATTAGAACTCCAATTACTTCAATTTGAGGCCGATACTGATTATCAAATTGAAGATCCACT
TAGTGCCATTAGCAAAATTCAACTTCCAGAACTCGATCTCAAAAACTTTGAAACTAGTGCGGATGTGGCACACGCTTGGT
ATAACTTACTAACTACCCACACCAAAAATGGAGAAGTCTATTTAGACCGCCTAACTCAACAAGGTTATTTCGTTAGTTTT
TACCCAACGACCACTAAGCCCCTTTTCTTCAATGGAAAAGCCCAAGCAGTCTTCGATCCTCATCAGTTGATCCGTGAAGT
AGTTTATGTGGAAGCCCCTCTCGATACTGATCATGATGGACAGCGCGATTTACTTAAAGCCGAAATTTTACGACCCGCTC
AAACTGCTCATGGATACCAAGCTCCAGTCCTATATACAGCGAGTCCTTATAATCAAGGGACAAATGATAGTTATGGAGAA
GCAATTACGCACAACGTTGATGTTCCTTTAACTGAAAAAGCGGTTCAAAAAATTTCTAAATCCGACGTCACTGCCGAACC
CTTCAGCCAAACACTTCCTGCTGAACGTAAAGTGGCTGGAATGGCTACAAAAGCAAGTGAAACTTTTGCTCGCGAACAGC
CCTATACTTTGAATAATTACTTCTTATCTCGGGGCTTCGCCGTGGTTTATGCTGCTGGGATTGGTACTCGAGATTCTGAT
GGACTTCGTGATACGGGCTCTGTCGAAGAAACCATTTCAACTACAGCAATCATCGAATGGCTAGCCGGCAATCGACGCGC
TTTTACTAACAAAACTGATAATCTTGAGATTAAAGCTTCTTGGTCTAATCATAAAATTGCCATGACGGGCCGCTCTTATC
TAGGCACCCTCGCCACTGCAGCTGCAACCACTGGGGTGGAAGGCTTAGAGACCATCATTTCAGAAGCAGCCATTTCTAGC
TGGTACGATTATTACCGAGACGGTGGTTTGGTCGCTGCTCCAGATACTTTCCAAGGCGAAGATATGGATGTCCTGGCCGC
TGAAGTTTTAAGTCGTAAACATGATGCTGGGGATTATTTAGGCATCAAAGCCCACTTTGATCAAATTTTGAAACGTATTG
AAAAAGATCAAGACCGTGACTCAGGTAATTATTCTAAATATTGGGACAGTAAGAATTATCTAAATAACGTTAAAAATATT
AAAGCTGATATTATAATGGTTCATGGCCTCAATGACTGGAACGTTAAACCACGAAATGTAGGTAAGCTTTGGAACGCTGT
TCGGGACTTACCGATCAATAAGAAAATTATTCTGCACCAAGGTCAACACATTTATATCAATGCTTTTCGTTCAATTGATT
TCACCGATATGATGAATCTATGGCTTAGTTACAAACTTTTTGACGTTCAAAATGGGGCTAACGAAGTCCTTCCTAATGTA
ATCATTCAAGATAATGTTGAACCTGAAACTTGGAACACTTATCAAGATTGGCAAGCAGCGGACGATGAGATTCGAGAATT
TACACTACAAGCTAAAACGCTGGTGGATCGTGCTTCTGAAACTAAAAACGAGGCAGCTTCATTTCGAGATTCCCTTGATC
CAGAATTTTTCGAAATGTATAAAAATGATTTAAAGCATTGGCATACTGATTTGCTAAACACAGAACATGCCACCAATGGT
AAAAATCAAATGCGTAATAATCGCTTGATTTTTAAAACAGCACAAACTAAAGAAGATTGGTTAATCGATGGTACGCCTGA
AGTTTCCGTTAACGTAGCAGTTAACCAACCATTTGGGATGCTTAGTTTCCAATTAGTTGATTTTGGAGATGCTAAACGTC
TCAATCCTTCACCTAGCATTCTCCAACCACGCTCTTTGAGTGGTAGTTTTGATTGGCGGACTGATGATCTACGCGAATTC
ACGCTTCAAAATGCGGTCACTCCTTGGAAAATGATTTCCAAAGGCCATATCAACTTACAAAATCGTACTAATAATTATTG
TGTTGATGAAGTTAAACCCCATCAATTCTATGATGTAAAATTAGAACTTCAACCTACGTTCTACCGCTTATTAGCCGGTC
ATCAATTAGGACTAGTTATCTATGCTACTGATTTTGAGACTACCATTCGTGGTAACCAAGAACTGCTTTACTCTTTACAG
TTAAACCAAAGTCATTTAAAAATAAAGTTAGCACACTAA

Upstream 100 bases:

>100_bases
AACGAACTTTTTCTTATTTTTAAAATATTTCAAGGCCTAATTATGTTTTATTGCTTTAGGCGTATAATATGAAACATAAA
TATTGTGGAGGTTCCATGTT

Downstream 100 bases:

>100_bases
TTTAATTTTTAAATTTATTATTGATTAAACCAATGGTAAATCAATATGGGTTCTGGTCAGTTTCCTTCAAATCTGATATT
ATAAGCTTAAATTTAAGAAA

Product: x-prolyl-dipeptidyl aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidyl-peptidase; X-prolyl-dipeptidyl aminopeptidase; X-PDAP

Number of amino acids: Translated: 812; Mature: 812

Protein sequence:

>812_residues
MKNNQFGRIRLDRTTELEELKNIHFIDADLLADPKAQLKDFLKRSCLVSNSEATFQQKLSNLLATPDQTMAAFFESDQPL
TLEIFILLELQLLQFEADTDYQIEDPLSAISKIQLPELDLKNFETSADVAHAWYNLLTTHTKNGEVYLDRLTQQGYFVSF
YPTTTKPLFFNGKAQAVFDPHQLIREVVYVEAPLDTDHDGQRDLLKAEILRPAQTAHGYQAPVLYTASPYNQGTNDSYGE
AITHNVDVPLTEKAVQKISKSDVTAEPFSQTLPAERKVAGMATKASETFAREQPYTLNNYFLSRGFAVVYAAGIGTRDSD
GLRDTGSVEETISTTAIIEWLAGNRRAFTNKTDNLEIKASWSNHKIAMTGRSYLGTLATAAATTGVEGLETIISEAAISS
WYDYYRDGGLVAAPDTFQGEDMDVLAAEVLSRKHDAGDYLGIKAHFDQILKRIEKDQDRDSGNYSKYWDSKNYLNNVKNI
KADIIMVHGLNDWNVKPRNVGKLWNAVRDLPINKKIILHQGQHIYINAFRSIDFTDMMNLWLSYKLFDVQNGANEVLPNV
IIQDNVEPETWNTYQDWQAADDEIREFTLQAKTLVDRASETKNEAASFRDSLDPEFFEMYKNDLKHWHTDLLNTEHATNG
KNQMRNNRLIFKTAQTKEDWLIDGTPEVSVNVAVNQPFGMLSFQLVDFGDAKRLNPSPSILQPRSLSGSFDWRTDDLREF
TLQNAVTPWKMISKGHINLQNRTNNYCVDEVKPHQFYDVKLELQPTFYRLLAGHQLGLVIYATDFETTIRGNQELLYSLQ
LNQSHLKIKLAH

Sequences:

>Translated_812_residues
MKNNQFGRIRLDRTTELEELKNIHFIDADLLADPKAQLKDFLKRSCLVSNSEATFQQKLSNLLATPDQTMAAFFESDQPL
TLEIFILLELQLLQFEADTDYQIEDPLSAISKIQLPELDLKNFETSADVAHAWYNLLTTHTKNGEVYLDRLTQQGYFVSF
YPTTTKPLFFNGKAQAVFDPHQLIREVVYVEAPLDTDHDGQRDLLKAEILRPAQTAHGYQAPVLYTASPYNQGTNDSYGE
AITHNVDVPLTEKAVQKISKSDVTAEPFSQTLPAERKVAGMATKASETFAREQPYTLNNYFLSRGFAVVYAAGIGTRDSD
GLRDTGSVEETISTTAIIEWLAGNRRAFTNKTDNLEIKASWSNHKIAMTGRSYLGTLATAAATTGVEGLETIISEAAISS
WYDYYRDGGLVAAPDTFQGEDMDVLAAEVLSRKHDAGDYLGIKAHFDQILKRIEKDQDRDSGNYSKYWDSKNYLNNVKNI
KADIIMVHGLNDWNVKPRNVGKLWNAVRDLPINKKIILHQGQHIYINAFRSIDFTDMMNLWLSYKLFDVQNGANEVLPNV
IIQDNVEPETWNTYQDWQAADDEIREFTLQAKTLVDRASETKNEAASFRDSLDPEFFEMYKNDLKHWHTDLLNTEHATNG
KNQMRNNRLIFKTAQTKEDWLIDGTPEVSVNVAVNQPFGMLSFQLVDFGDAKRLNPSPSILQPRSLSGSFDWRTDDLREF
TLQNAVTPWKMISKGHINLQNRTNNYCVDEVKPHQFYDVKLELQPTFYRLLAGHQLGLVIYATDFETTIRGNQELLYSLQ
LNQSHLKIKLAH
>Mature_812_residues
MKNNQFGRIRLDRTTELEELKNIHFIDADLLADPKAQLKDFLKRSCLVSNSEATFQQKLSNLLATPDQTMAAFFESDQPL
TLEIFILLELQLLQFEADTDYQIEDPLSAISKIQLPELDLKNFETSADVAHAWYNLLTTHTKNGEVYLDRLTQQGYFVSF
YPTTTKPLFFNGKAQAVFDPHQLIREVVYVEAPLDTDHDGQRDLLKAEILRPAQTAHGYQAPVLYTASPYNQGTNDSYGE
AITHNVDVPLTEKAVQKISKSDVTAEPFSQTLPAERKVAGMATKASETFAREQPYTLNNYFLSRGFAVVYAAGIGTRDSD
GLRDTGSVEETISTTAIIEWLAGNRRAFTNKTDNLEIKASWSNHKIAMTGRSYLGTLATAAATTGVEGLETIISEAAISS
WYDYYRDGGLVAAPDTFQGEDMDVLAAEVLSRKHDAGDYLGIKAHFDQILKRIEKDQDRDSGNYSKYWDSKNYLNNVKNI
KADIIMVHGLNDWNVKPRNVGKLWNAVRDLPINKKIILHQGQHIYINAFRSIDFTDMMNLWLSYKLFDVQNGANEVLPNV
IIQDNVEPETWNTYQDWQAADDEIREFTLQAKTLVDRASETKNEAASFRDSLDPEFFEMYKNDLKHWHTDLLNTEHATNG
KNQMRNNRLIFKTAQTKEDWLIDGTPEVSVNVAVNQPFGMLSFQLVDFGDAKRLNPSPSILQPRSLSGSFDWRTDDLREF
TLQNAVTPWKMISKGHINLQNRTNNYCVDEVKPHQFYDVKLELQPTFYRLLAGHQLGLVIYATDFETTIRGNQELLYSLQ
LNQSHLKIKLAH

Specific function: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S15 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPX_PEDPA (Q03H46)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_803918.1
- ProteinModelPortal:   Q03H46
- SMR:   Q03H46
- STRING:   Q03H46
- MEROPS:   S15.001
- GeneID:   4418451
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0380
- NMPDR:   fig|278197.10.peg.353
- eggNOG:   NOG04844
- HOGENOM:   HBG515455
- OMA:   NDWNVKP
- ProtClustDB:   PRK05371
- BioCyc:   PPEN278197:PEPE_0380-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00698
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR008252
- InterPro:   IPR000383
- InterPro:   IPR015251
- PRINTS:   PR00923
- SMART:   SM00939
- SMART:   SM00940

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C; PF09168 PepX_N; SSF49785 Gal_bind_like; SSF81761 PepX_N

EC number: =3.4.14.11

Molecular weight: Translated: 92355; Mature: 92355

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: ACT_SITE 372-372 ACT_SITE 492-492 ACT_SITE 523-523

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNQFGRIRLDRTTELEELKNIHFIDADLLADPKAQLKDFLKRSCLVSNSEATFQQKLS
CCCCCEEEEEECCCCCHHHHCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
NLLATPDQTMAAFFESDQPLTLEIFILLELQLLQFEADTDYQIEDPLSAISKIQLPELDL
HHHCCCCHHHHHHHCCCCCEEEEEEEEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCC
KNFETSADVAHAWYNLLTTHTKNGEVYLDRLTQQGYFVSFYPTTTKPLFFNGKAQAVFDP
CCCCCHHHHHHHHHHHHHEECCCCCEEEEEECCCCEEEEEECCCCCCEEECCCCCEEECH
HQLIREVVYVEAPLDTDHDGQRDLLKAEILRPAQTAHGYQAPVLYTASPYNQGTNDSYGE
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCCCCC
AITHNVDVPLTEKAVQKISKSDVTAEPFSQTLPAERKVAGMATKASETFAREQPYTLNNY
CEEECCCCCCHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
FLSRGFAVVYAAGIGTRDSDGLRDTGSVEETISTTAIIEWLAGNRRAFTNKTDNLEIKAS
HHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEE
WSNHKIAMTGRSYLGTLATAAATTGVEGLETIISEAAISSWYDYYRDGGLVAAPDTFQGE
CCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
DMDVLAAEVLSRKHDAGDYLGIKAHFDQILKRIEKDQDRDSGNYSKYWDSKNYLNNVKNI
CHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHCC
KADIIMVHGLNDWNVKPRNVGKLWNAVRDLPINKKIILHQGQHIYINAFRSIDFTDMMNL
EEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCCHHHHHHH
WLSYKLFDVQNGANEVLPNVIIQDNVEPETWNTYQDWQAADDEIREFTLQAKTLVDRASE
HHEEEEEEECCCHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TKNEAASFRDSLDPEFFEMYKNDLKHWHTDLLNTEHATNGKNQMRNNRLIFKTAQTKEDW
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEEECCCCCCE
LIDGTPEVSVNVAVNQPFGMLSFQLVDFGDAKRLNPSPSILQPRSLSGSFDWRTDDLREF
EECCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
TLQNAVTPWKMISKGHINLQNRTNNYCVDEVKPHQFYDVKLELQPTFYRLLAGHQLGLVI
HHHHCCCCHHHHCCCCEEECCCCCCEECCCCCCCEEEEEEEEECHHHHHHHCCCCEEEEE
YATDFETTIRGNQELLYSLQLNQSHLKIKLAH
EEECCCHHHCCCCEEEEEEEECCCEEEEEECC
>Mature Secondary Structure
MKNNQFGRIRLDRTTELEELKNIHFIDADLLADPKAQLKDFLKRSCLVSNSEATFQQKLS
CCCCCEEEEEECCCCCHHHHCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
NLLATPDQTMAAFFESDQPLTLEIFILLELQLLQFEADTDYQIEDPLSAISKIQLPELDL
HHHCCCCHHHHHHHCCCCCEEEEEEEEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCC
KNFETSADVAHAWYNLLTTHTKNGEVYLDRLTQQGYFVSFYPTTTKPLFFNGKAQAVFDP
CCCCCHHHHHHHHHHHHHEECCCCCEEEEEECCCCEEEEEECCCCCCEEECCCCCEEECH
HQLIREVVYVEAPLDTDHDGQRDLLKAEILRPAQTAHGYQAPVLYTASPYNQGTNDSYGE
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCCCCC
AITHNVDVPLTEKAVQKISKSDVTAEPFSQTLPAERKVAGMATKASETFAREQPYTLNNY
CEEECCCCCCHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
FLSRGFAVVYAAGIGTRDSDGLRDTGSVEETISTTAIIEWLAGNRRAFTNKTDNLEIKAS
HHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEE
WSNHKIAMTGRSYLGTLATAAATTGVEGLETIISEAAISSWYDYYRDGGLVAAPDTFQGE
CCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
DMDVLAAEVLSRKHDAGDYLGIKAHFDQILKRIEKDQDRDSGNYSKYWDSKNYLNNVKNI
CHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHCC
KADIIMVHGLNDWNVKPRNVGKLWNAVRDLPINKKIILHQGQHIYINAFRSIDFTDMMNL
EEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCCHHHHHHH
WLSYKLFDVQNGANEVLPNVIIQDNVEPETWNTYQDWQAADDEIREFTLQAKTLVDRASE
HHEEEEEEECCCHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TKNEAASFRDSLDPEFFEMYKNDLKHWHTDLLNTEHATNGKNQMRNNRLIFKTAQTKEDW
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEEECCCCCCE
LIDGTPEVSVNVAVNQPFGMLSFQLVDFGDAKRLNPSPSILQPRSLSGSFDWRTDDLREF
EECCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
TLQNAVTPWKMISKGHINLQNRTNNYCVDEVKPHQFYDVKLELQPTFYRLLAGHQLGLVI
HHHHCCCCHHHHCCCCEEECCCCCCEECCCCCCCEEEEEEEEECHHHHHHHCCCCEEEEE
YATDFETTIRGNQELLYSLQLNQSHLKIKLAH
EEECCCHHHCCCCEEEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA