| Definition | Pediococcus pentosaceus ATCC 25745, complete genome. |
|---|---|
| Accession | NC_008525 |
| Length | 1,832,387 |
Click here to switch to the map view.
The map label for this gene is yvgN [H]
Identifier: 116492181
GI number: 116492181
Start: 423951
End: 424802
Strand: Reverse
Name: yvgN [H]
Synonym: PEPE_0378
Alternate gene names: 116492181
Gene position: 424802-423951 (Counterclockwise)
Preceding gene: 116492182
Following gene: 116492179
Centisome position: 23.18
GC content: 40.49
Gene sequence:
>852_bases ATGAATAATTTAACAGATACTTATACCCTTAACAACGGAGTTAAAATCCCCGTAGTTGGTTTTGGAACTTGGCAATCTAA AGATGGTGATGAAGCTTATAATGCAGTTAAGGCTGCTTTAGAAGCGGGCTACCGTCATATTGATACAGCTGCAGCTTATG GAAACGAAGAAAGTGTTGGCAAAGCCATTAAAGATAGTGGAATTGATCGTAAAGAACTTTTCATCACGTCTAAACTATGG AATCGTGACCATGGCTACGAATCAGCTAAAAAAGCGTTAGACACTAGTTTAGCTAAATTAGGTACTGATTACCTCGACTT ATACCTAATTCACTGGCCAAATCCAGTCCAATTCCGTGATGAATGGCAACAGCGCAACGCTGACTCATGGCGTGCGATGG AAGAAGCCCTCGATGCTGGTAAAGTACGTGCGATTGGTGTATCTAATTTCCGTGCTCATCATCTTGATGAACTTTTGAAA ACTGCCAAAGTAACTCCAGCAGTCAACCAAATCTTCCTAAATCCTAGTGATACTGAAGATGAAGTTGTGGCCTACAATAA AGAACATGGTATTCTTTCGGAAGCATATAGTCCACTAGGAACTGGTAAGATTTTTACCATTCCAGAACTTAAAGATATCG CTGCTAAATACAATAAGAGTGTCGCTCAAGTCGTACTTCGTTGGTCACTACAACACGGCTTCTTACCTCTTCCTAAGTCA GTTCACGCTGACCGTATTAAACAAAACACCGAAATCTTTGATTTTGAACTTTCAGATGACGACATCAAGAAAATTGATGG TTTCCATGGTGTAGCTGGTCTAGCTCAGGATCCAGATGCCACAGACTTTTAA
Upstream 100 bases:
>100_bases AAAAGGACTAACTAATTTTTAGTTAGTCCTTTTTACTAGCTTACCGCCTGTAAAAGCGCTATTATTAATATAGTTTATTG GTAATCAAGGAGGCTTTTTG
Downstream 100 bases:
>100_bases GCTATTGAGTATTAAAAAAGCAACCCCACGGGGTTGCTTTTTTGCTTGGTTATTCGCGATCTAGACGTAATTTTTCCACG TTGATTTCTTTATCAATCCA
Product: aldo/keto reductase
Products: NA
Alternate protein names: GR; Methylglyoxal reductase [H]
Number of amino acids: Translated: 283; Mature: 283
Protein sequence:
>283_residues MNNLTDTYTLNNGVKIPVVGFGTWQSKDGDEAYNAVKAALEAGYRHIDTAAAYGNEESVGKAIKDSGIDRKELFITSKLW NRDHGYESAKKALDTSLAKLGTDYLDLYLIHWPNPVQFRDEWQQRNADSWRAMEEALDAGKVRAIGVSNFRAHHLDELLK TAKVTPAVNQIFLNPSDTEDEVVAYNKEHGILSEAYSPLGTGKIFTIPELKDIAAKYNKSVAQVVLRWSLQHGFLPLPKS VHADRIKQNTEIFDFELSDDDIKKIDGFHGVAGLAQDPDATDF
Sequences:
>Translated_283_residues MNNLTDTYTLNNGVKIPVVGFGTWQSKDGDEAYNAVKAALEAGYRHIDTAAAYGNEESVGKAIKDSGIDRKELFITSKLW NRDHGYESAKKALDTSLAKLGTDYLDLYLIHWPNPVQFRDEWQQRNADSWRAMEEALDAGKVRAIGVSNFRAHHLDELLK TAKVTPAVNQIFLNPSDTEDEVVAYNKEHGILSEAYSPLGTGKIFTIPELKDIAAKYNKSVAQVVLRWSLQHGFLPLPKS VHADRIKQNTEIFDFELSDDDIKKIDGFHGVAGLAQDPDATDF >Mature_283_residues MNNLTDTYTLNNGVKIPVVGFGTWQSKDGDEAYNAVKAALEAGYRHIDTAAAYGNEESVGKAIKDSGIDRKELFITSKLW NRDHGYESAKKALDTSLAKLGTDYLDLYLIHWPNPVQFRDEWQQRNADSWRAMEEALDAGKVRAIGVSNFRAHHLDELLK TAKVTPAVNQIFLNPSDTEDEVVAYNKEHGILSEAYSPLGTGKIFTIPELKDIAAKYNKSVAQVVLRWSLQHGFLPLPKS VHADRIKQNTEIFDFELSDDDIKKIDGFHGVAGLAQDPDATDF
Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=287, Percent_Identity=38.6759581881533, Blast_Score=214, Evalue=5e-56, Organism=Homo sapiens, GI5174391, Length=287, Percent_Identity=38.6759581881533, Blast_Score=214, Evalue=5e-56, Organism=Homo sapiens, GI223468663, Length=288, Percent_Identity=38.1944444444444, Blast_Score=198, Evalue=4e-51, Organism=Homo sapiens, GI4502049, Length=288, Percent_Identity=40.9722222222222, Blast_Score=189, Evalue=2e-48, Organism=Homo sapiens, GI310109920, Length=300, Percent_Identity=35.6666666666667, Blast_Score=184, Evalue=8e-47, Organism=Homo sapiens, GI45446745, Length=300, Percent_Identity=35.6666666666667, Blast_Score=184, Evalue=1e-46, Organism=Homo sapiens, GI4503285, Length=300, Percent_Identity=35.6666666666667, Blast_Score=184, Evalue=1e-46, Organism=Homo sapiens, GI5453543, Length=300, Percent_Identity=35.3333333333333, Blast_Score=183, Evalue=2e-46, Organism=Homo sapiens, GI5174695, Length=292, Percent_Identity=35.2739726027397, Blast_Score=182, Evalue=2e-46, Organism=Homo sapiens, GI24497583, Length=299, Percent_Identity=35.4515050167224, Blast_Score=181, Evalue=8e-46, Organism=Homo sapiens, GI310109922, Length=288, Percent_Identity=36.4583333333333, Blast_Score=181, Evalue=9e-46, Organism=Homo sapiens, GI24497585, Length=291, Percent_Identity=35.0515463917526, Blast_Score=174, Evalue=1e-43, Organism=Homo sapiens, GI291291012, Length=263, Percent_Identity=36.1216730038023, Blast_Score=169, Evalue=2e-42, Organism=Homo sapiens, GI300116273, Length=275, Percent_Identity=34.9090909090909, Blast_Score=166, Evalue=2e-41, Organism=Homo sapiens, GI93277124, Length=306, Percent_Identity=33.0065359477124, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI300116271, Length=279, Percent_Identity=31.8996415770609, Blast_Score=144, Evalue=7e-35, Organism=Homo sapiens, GI310109926, Length=123, Percent_Identity=44.7154471544715, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI207028673, Length=123, Percent_Identity=44.7154471544715, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI310109924, Length=150, Percent_Identity=32.6666666666667, Blast_Score=88, Evalue=8e-18, Organism=Escherichia coli, GI87082198, Length=272, Percent_Identity=43.0147058823529, Blast_Score=226, Evalue=2e-60, Organism=Escherichia coli, GI1786400, Length=256, Percent_Identity=38.28125, Blast_Score=160, Evalue=1e-40, Organism=Escherichia coli, GI1788081, Length=269, Percent_Identity=32.3420074349442, Blast_Score=120, Evalue=8e-29, Organism=Escherichia coli, GI1788070, Length=305, Percent_Identity=24.5901639344262, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI48994888, Length=252, Percent_Identity=29.3650793650794, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1789375, Length=320, Percent_Identity=22.5, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI87081735, Length=184, Percent_Identity=27.1739130434783, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71998625, Length=266, Percent_Identity=40.9774436090226, Blast_Score=204, Evalue=5e-53, Organism=Caenorhabditis elegans, GI17564128, Length=295, Percent_Identity=36.9491525423729, Blast_Score=193, Evalue=9e-50, Organism=Caenorhabditis elegans, GI17537077, Length=293, Percent_Identity=38.9078498293515, Blast_Score=190, Evalue=9e-49, Organism=Caenorhabditis elegans, GI17537075, Length=291, Percent_Identity=38.8316151202749, Blast_Score=186, Evalue=1e-47, Organism=Caenorhabditis elegans, GI17550248, Length=294, Percent_Identity=38.4353741496599, Blast_Score=177, Evalue=4e-45, Organism=Caenorhabditis elegans, GI17537079, Length=298, Percent_Identity=34.2281879194631, Blast_Score=177, Evalue=7e-45, Organism=Caenorhabditis elegans, GI17561298, Length=269, Percent_Identity=37.1747211895911, Blast_Score=172, Evalue=3e-43, Organism=Caenorhabditis elegans, GI17552492, Length=273, Percent_Identity=33.3333333333333, Blast_Score=169, Evalue=2e-42, Organism=Caenorhabditis elegans, GI17538386, Length=273, Percent_Identity=34.7985347985348, Blast_Score=162, Evalue=1e-40, Organism=Caenorhabditis elegans, GI17566692, Length=299, Percent_Identity=32.7759197324415, Blast_Score=159, Evalue=2e-39, Organism=Caenorhabditis elegans, GI17561300, Length=266, Percent_Identity=33.4586466165414, Blast_Score=147, Evalue=5e-36, Organism=Caenorhabditis elegans, GI17562292, Length=274, Percent_Identity=30.6569343065693, Blast_Score=134, Evalue=5e-32, Organism=Caenorhabditis elegans, GI17550246, Length=77, Percent_Identity=48.0519480519481, Blast_Score=70, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6320576, Length=299, Percent_Identity=42.809364548495, Blast_Score=228, Evalue=6e-61, Organism=Saccharomyces cerevisiae, GI6324694, Length=297, Percent_Identity=43.0976430976431, Blast_Score=225, Evalue=5e-60, Organism=Saccharomyces cerevisiae, GI6322556, Length=287, Percent_Identity=41.1149825783972, Blast_Score=201, Evalue=1e-52, Organism=Saccharomyces cerevisiae, GI6321896, Length=309, Percent_Identity=33.6569579288026, Blast_Score=167, Evalue=2e-42, Organism=Saccharomyces cerevisiae, GI6319625, Length=292, Percent_Identity=35.958904109589, Blast_Score=159, Evalue=4e-40, Organism=Saccharomyces cerevisiae, GI6320079, Length=292, Percent_Identity=34.5890410958904, Blast_Score=152, Evalue=4e-38, Organism=Drosophila melanogaster, GI20129731, Length=289, Percent_Identity=36.6782006920415, Blast_Score=205, Evalue=3e-53, Organism=Drosophila melanogaster, GI24663317, Length=292, Percent_Identity=37.6712328767123, Blast_Score=204, Evalue=4e-53, Organism=Drosophila melanogaster, GI24657054, Length=284, Percent_Identity=40.1408450704225, Blast_Score=202, Evalue=1e-52, Organism=Drosophila melanogaster, GI24644950, Length=316, Percent_Identity=38.6075949367089, Blast_Score=197, Evalue=8e-51, Organism=Drosophila melanogaster, GI24662789, Length=294, Percent_Identity=38.4353741496599, Blast_Score=192, Evalue=3e-49, Organism=Drosophila melanogaster, GI221378297, Length=336, Percent_Identity=36.3095238095238, Blast_Score=190, Evalue=1e-48, Organism=Drosophila melanogaster, GI45553081, Length=289, Percent_Identity=36.6782006920415, Blast_Score=185, Evalue=3e-47, Organism=Drosophila melanogaster, GI21356425, Length=283, Percent_Identity=37.1024734982332, Blast_Score=183, Evalue=1e-46, Organism=Drosophila melanogaster, GI24662781, Length=283, Percent_Identity=38.5159010600707, Blast_Score=168, Evalue=4e-42, Organism=Drosophila melanogaster, GI24662785, Length=281, Percent_Identity=38.4341637010676, Blast_Score=162, Evalue=3e-40, Organism=Drosophila melanogaster, GI281366140, Length=250, Percent_Identity=36, Blast_Score=158, Evalue=3e-39,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.283 [H]
Molecular weight: Translated: 31581; Mature: 31581
Theoretical pI: Translated: 5.21; Mature: 5.21
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 0.7 %Met (Translated Protein) 0.7 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 0.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNNLTDTYTLNNGVKIPVVGFGTWQSKDGDEAYNAVKAALEAGYRHIDTAAAYGNEESVG CCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHH KAIKDSGIDRKELFITSKLWNRDHGYESAKKALDTSLAKLGTDYLDLYLIHWPNPVQFRD HHHHHCCCCHHHHEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHH EWQQRNADSWRAMEEALDAGKVRAIGVSNFRAHHLDELLKTAKVTPAVNQIFLNPSDTED HHHHCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCCC EVVAYNKEHGILSEAYSPLGTGKIFTIPELKDIAAKYNKSVAQVVLRWSLQHGFLPLPKS CEEEECCCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH VHADRIKQNTEIFDFELSDDDIKKIDGFHGVAGLAQDPDATDF HHHHHHHCCCEEEEEECCCCHHHHHCCHHCCCCCCCCCCCCCC >Mature Secondary Structure MNNLTDTYTLNNGVKIPVVGFGTWQSKDGDEAYNAVKAALEAGYRHIDTAAAYGNEESVG CCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHH KAIKDSGIDRKELFITSKLWNRDHGYESAKKALDTSLAKLGTDYLDLYLIHWPNPVQFRD HHHHHCCCCHHHHEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHH EWQQRNADSWRAMEEALDAGKVRAIGVSNFRAHHLDELLKTAKVTPAVNQIFLNPSDTED HHHHCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCCC EVVAYNKEHGILSEAYSPLGTGKIFTIPELKDIAAKYNKSVAQVVLRWSLQHGFLPLPKS CEEEECCCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH VHADRIKQNTEIFDFELSDDDIKKIDGFHGVAGLAQDPDATDF HHHHHHHCCCEEEEEECCCCHHHHHCCHHCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9639930; 9384377 [H]