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The map label for this gene is kcsA [H]

Identifier: 116492104

GI number: 116492104

Start: 344617

End: 345369

Strand: Reverse

Name: kcsA [H]

Synonym: PEPE_0300

Alternate gene names: 116492104

Gene position: 345369-344617 (Counterclockwise)

Preceding gene: 116492109

Following gene: 116492102

Centisome position: 18.85

GC content: 35.46

Gene sequence:

>753_bases
ATGATAAAACATAGAACCAGATTCCAAATTTTATATGATAGTTGTTTGGCTATGATTGCTTTTATTTCATTCCTAATCGT
TGCCGCTTCGTTTTTTTCTAAGAGTATTAGTCTGAAAAATACGACCATTTTAAATCTAATGCATGTATTTTTAATCATTT
ATGCGGTCGACTTTTTTGCGAGAATGCCTAAAAATAAAAATGCTCATCGTTATCTTTTTGACAATACTTTTGATTTGTTA
TCGTTAATCCCACTACATCCGGCTTTTGCTATCTTTCGAATTGGTCGAGTTTTCAAATTAATTCGCAGCCATCATTTATT
ATGGCGTTTTGGATTAGATGGAAAATTTTCTAAGACCGTTCATCGGTTTATCTATACCTCGGGCTTCTTAAACCTTTTTA
CCGTCAGTATGATTATTTTAGTTTTAAGCTCGCTCCTTTATTCTGTGGTAGAACATATTTCATATCCTTCAGCCCTATGG
TGGGCCATTACGACTGCCACCACTGTTGGTTATGGTGATATTTCACCTACCACCAACATTGGTAAATTTATTGCCGCCTT
TCTAATGATTGGTGGTGTTGGGTTCATTGGTTTGCTCACTAGTACAATTACAGGATTCTTTACTTCTGAAGCTGCTACGC
AGGAAGATGATATGACCAAGCTTTTCAAAAAAATCGATCAACTTGATCATAAAATCGACCATCTCCAGCGTCAGCTCAAT
CTAGAACGACGTAAAAATACGCGAAAAAAATAA

Upstream 100 bases:

>100_bases
TCCTCTTTATTATTAGTTATTCATATCATATCATTTTCTTGGCTATTTACAGCTCCTCAAAATGCGTTAAAATAATTCTA
TTAATTCAGAGGACGTTAAT

Downstream 100 bases:

>100_bases
GGATTAACGTTTTGAGACGAAATTATTCGCCCAGCGTTAATCCTTATTTTTTTAGATTAGCTATTATTCTTCGCTACCCA
TTGCCTTAGCAACAAAAGCA

Product: Kef-type K+ transporter NAD-binding component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MIKHRTRFQILYDSCLAMIAFISFLIVAASFFSKSISLKNTTILNLMHVFLIIYAVDFFARMPKNKNAHRYLFDNTFDLL
SLIPLHPAFAIFRIGRVFKLIRSHHLLWRFGLDGKFSKTVHRFIYTSGFLNLFTVSMIILVLSSLLYSVVEHISYPSALW
WAITTATTVGYGDISPTTNIGKFIAAFLMIGGVGFIGLLTSTITGFFTSEAATQEDDMTKLFKKIDQLDHKIDHLQRQLN
LERRKNTRKK

Sequences:

>Translated_250_residues
MIKHRTRFQILYDSCLAMIAFISFLIVAASFFSKSISLKNTTILNLMHVFLIIYAVDFFARMPKNKNAHRYLFDNTFDLL
SLIPLHPAFAIFRIGRVFKLIRSHHLLWRFGLDGKFSKTVHRFIYTSGFLNLFTVSMIILVLSSLLYSVVEHISYPSALW
WAITTATTVGYGDISPTTNIGKFIAAFLMIGGVGFIGLLTSTITGFFTSEAATQEDDMTKLFKKIDQLDHKIDHLQRQLN
LERRKNTRKK
>Mature_250_residues
MIKHRTRFQILYDSCLAMIAFISFLIVAASFFSKSISLKNTTILNLMHVFLIIYAVDFFARMPKNKNAHRYLFDNTFDLL
SLIPLHPAFAIFRIGRVFKLIRSHHLLWRFGLDGKFSKTVHRFIYTSGFLNLFTVSMIILVLSSLLYSVVEHISYPSALW
WAITTATTVGYGDISPTTNIGKFIAAFLMIGGVGFIGLLTSTITGFFTSEAATQEDDMTKLFKKIDQLDHKIDHLQRQLN
LERRKNTRKK

Specific function: Acts as a potassium ion channel [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the potassium channel family [H]

Homologues:

Organism=Homo sapiens, GI27436974, Length=147, Percent_Identity=34.6938775510204, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4826784, Length=147, Percent_Identity=34.6938775510204, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71989369, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71989381, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71989361, Length=189, Percent_Identity=30.1587301587302, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71989376, Length=189, Percent_Identity=30.1587301587302, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17544122, Length=181, Percent_Identity=24.8618784530387, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281365536, Length=193, Percent_Identity=33.6787564766839, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007764, Length=193, Percent_Identity=33.6787564766839, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24656289, Length=193, Percent_Identity=33.6787564766839, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24656294, Length=193, Percent_Identity=33.6787564766839, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003091 [H]

Pfam domain/function: PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 28700; Mature: 28700

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKHRTRFQILYDSCLAMIAFISFLIVAASFFSKSISLKNTTILNLMHVFLIIYAVDFFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RMPKNKNAHRYLFDNTFDLLSLIPLHPAFAIFRIGRVFKLIRSHHLLWRFGLDGKFSKTV
HCCCCCCCCEEHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHH
HRFIYTSGFLNLFTVSMIILVLSSLLYSVVEHISYPSALWWAITTATTVGYGDISPTTNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHH
GKFIAAFLMIGGVGFIGLLTSTITGFFTSEAATQEDDMTKLFKKIDQLDHKIDHLQRQLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LERRKNTRKK
HHHHHCCCCC
>Mature Secondary Structure
MIKHRTRFQILYDSCLAMIAFISFLIVAASFFSKSISLKNTTILNLMHVFLIIYAVDFFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RMPKNKNAHRYLFDNTFDLLSLIPLHPAFAIFRIGRVFKLIRSHHLLWRFGLDGKFSKTV
HCCCCCCCCEEHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHH
HRFIYTSGFLNLFTVSMIILVLSSLLYSVVEHISYPSALWWAITTATTVGYGDISPTTNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHH
GKFIAAFLMIGGVGFIGLLTSTITGFFTSEAATQEDDMTKLFKKIDQLDHKIDHLQRQLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LERRKNTRKK
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]