Click here to switch to the map view.

The map label for this gene is yceI [H]

Identifier: 116492021

GI number: 116492021

Start: 253883

End: 255067

Strand: Reverse

Name: yceI [H]

Synonym: PEPE_0213

Alternate gene names: 116492021

Gene position: 255067-253883 (Counterclockwise)

Preceding gene: 116492024

Following gene: 116492020

Centisome position: 13.92

GC content: 42.11

Gene sequence:

>1185_bases
TTGAATGGAATTTCAAACTATAAAAAATTACTAGCAGCTTCGGGGGTAGCCTGGCTTTTTGATGCCATGGACGTTGGTAT
ATTATCTTTTGTAATTGCTGCTTTAACGTCAGAGTGGCATTTAACTGAATCACAGGTTGGCATGATTGGTAGTATCAGTT
CACTTGGGATGGCTGTAGGCGCTATTTTATTTGGAGCGCTGGCCGACCGTTACAATCGAAAAACAATTTTAATTATTAGT
TTACTAATTTTCTCAATTTTTAACGGTATTTCAGCTTTCACCACTACCTATGCGGCTTTTGTTATGATTCGTTTTATTGT
CGGTTGTGGATTGGGTGGTGAACTACCTGTTGCTTCGACTTTAATCTCGGAGAGCGCCCCTGCTCATGTTCGAGGGCGGG
CAGTAGTGCTCCTCGAAAGTTTTTGGGCTGGCGGTTGGTTAATTTCGGCTTTAATCTCTTATTTTATCATTCCCAGTTGG
GGCTGGCGGATTGCCGTGTTTATCACTTCCTTAGCGGCGCTCTATGCCTTGGTTCTCCGTTTTAGTATTCGCGAAGCAGA
TTCAAATCATTCTTTTACACCCAAAGCTCGCCTAGCTTTACGTTTAAAAAATATTTGGAGTCGTCCCTATGCTAAAGCCA
CGTTGATGCTTTGGATTGTTTGGTTTATGGTTGTATTCTCATATTATGGAATGTTTCTTTGGTTGCCTAGTGTCATGGTG
ATGAAGGGGTATAGTATTGTTCACAGTTTTGGTTATGTGTTAATCATGACTGTGGCACAACTTCCGGGTTACTTTATGGC
AGCTTGGTTAATTGAGCGATGGGGACGCAAATGGACTTTGATGGTTTTCTTATTCGGTACTGCCGTCAGTGCTATCGCCT
TTGGTTTTGCTCAAGGGCTGATGATGTTATTGTTAGCTGGTATTTTACTATCCTTCTTTAATCTTGGTGCTTGGGGCGCA
CTCTATGCCTATTCTCCGGAGCAATATCCTGAAGAAATTCGTGGAACAGGTTCCGGGCTAGCAGCCGGAATTGGGCGCAT
CGGTGGGATCGTAGGCCCTCTTTTGGTGGGATTTTTAACTGAAAAAGGCGTTGCTTTATCAACTACTTTTATAATTTTCT
TCATCTCCATTATGATAGCTGTAATTGCAATCGGCTTCCTAGGTAAAGAAACTATGGAAAAATAA

Upstream 100 bases:

>100_bases
GACATTAATTTTAAATAAATCATTGATAAATATTGTTTTATGTTGTAATCTTGTATTCAACTCAGAGTGTGTCTTGACAC
TAAAAAGGAGAATGATGATT

Downstream 100 bases:

>100_bases
TTTTTATGAGAAAATTTTTACGCTATCCCTAGCTTTAATGCTCTTCTAGTATCACTTCTATAGCGCCTTAATTGGAGAGG
TATTTGCCACAACTCCATCA

Product: major facilitator superfamily permease

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNGISNYKKLLAASGVAWLFDAMDVGILSFVIAALTSEWHLTESQVGMIGSISSLGMAVGAILFGALADRYNRKTILIIS
LLIFSIFNGISAFTTTYAAFVMIRFIVGCGLGGELPVASTLISESAPAHVRGRAVVLLESFWAGGWLISALISYFIIPSW
GWRIAVFITSLAALYALVLRFSIREADSNHSFTPKARLALRLKNIWSRPYAKATLMLWIVWFMVVFSYYGMFLWLPSVMV
MKGYSIVHSFGYVLIMTVAQLPGYFMAAWLIERWGRKWTLMVFLFGTAVSAIAFGFAQGLMMLLLAGILLSFFNLGAWGA
LYAYSPEQYPEEIRGTGSGLAAGIGRIGGIVGPLLVGFLTEKGVALSTTFIIFFISIMIAVIAIGFLGKETMEK

Sequences:

>Translated_394_residues
MNGISNYKKLLAASGVAWLFDAMDVGILSFVIAALTSEWHLTESQVGMIGSISSLGMAVGAILFGALADRYNRKTILIIS
LLIFSIFNGISAFTTTYAAFVMIRFIVGCGLGGELPVASTLISESAPAHVRGRAVVLLESFWAGGWLISALISYFIIPSW
GWRIAVFITSLAALYALVLRFSIREADSNHSFTPKARLALRLKNIWSRPYAKATLMLWIVWFMVVFSYYGMFLWLPSVMV
MKGYSIVHSFGYVLIMTVAQLPGYFMAAWLIERWGRKWTLMVFLFGTAVSAIAFGFAQGLMMLLLAGILLSFFNLGAWGA
LYAYSPEQYPEEIRGTGSGLAAGIGRIGGIVGPLLVGFLTEKGVALSTTFIIFFISIMIAVIAIGFLGKETMEK
>Mature_394_residues
MNGISNYKKLLAASGVAWLFDAMDVGILSFVIAALTSEWHLTESQVGMIGSISSLGMAVGAILFGALADRYNRKTILIIS
LLIFSIFNGISAFTTTYAAFVMIRFIVGCGLGGELPVASTLISESAPAHVRGRAVVLLESFWAGGWLISALISYFIIPSW
GWRIAVFITSLAALYALVLRFSIREADSNHSFTPKARLALRLKNIWSRPYAKATLMLWIVWFMVVFSYYGMFLWLPSVMV
MKGYSIVHSFGYVLIMTVAQLPGYFMAAWLIERWGRKWTLMVFLFGTAVSAIAFGFAQGLMMLLLAGILLSFFNLGAWGA
LYAYSPEQYPEEIRGTGSGLAAGIGRIGGIVGPLLVGFLTEKGVALSTTFIIFFISIMIAVIAIGFLGKETMEK

Specific function: Could Be A Transporter For 3-Phenylpropionate (Hydrocinnamic Acid). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=437, Percent_Identity=29.2906178489703, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI213021148, Length=403, Percent_Identity=26.5508684863524, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI7662270, Length=300, Percent_Identity=28.3333333333333, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI216548223, Length=148, Percent_Identity=37.1621621621622, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI90669191, Length=370, Percent_Identity=27.5675675675676, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI24497497, Length=371, Percent_Identity=27.2237196765499, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI262399383, Length=260, Percent_Identity=26.1538461538462, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI166197673, Length=391, Percent_Identity=26.8542199488491, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI73695465, Length=300, Percent_Identity=25.6666666666667, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI24497476, Length=385, Percent_Identity=24.9350649350649, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI20070188, Length=385, Percent_Identity=24.9350649350649, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4507005, Length=378, Percent_Identity=21.957671957672, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87081723, Length=340, Percent_Identity=29.4117647058824, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87082404, Length=357, Percent_Identity=26.0504201680672, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082231, Length=180, Percent_Identity=29.4444444444444, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082159, Length=365, Percent_Identity=24.6575342465753, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786229, Length=371, Percent_Identity=20.2156334231806, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788074, Length=372, Percent_Identity=23.3870967741935, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788068, Length=378, Percent_Identity=22.4867724867725, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790550, Length=431, Percent_Identity=23.4338747099768, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=408, Percent_Identity=28.4313725490196, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI19922874, Length=423, Percent_Identity=23.1678486997636, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24640198, Length=458, Percent_Identity=23.5807860262009, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640196, Length=458, Percent_Identity=23.5807860262009, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640200, Length=458, Percent_Identity=23.5807860262009, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24649616, Length=371, Percent_Identity=24.2587601078167, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43085; Mature: 43085

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGISNYKKLLAASGVAWLFDAMDVGILSFVIAALTSEWHLTESQVGMIGSISSLGMAVG
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AILFGALADRYNRKTILIISLLIFSIFNGISAFTTTYAAFVMIRFIVGCGLGGELPVAST
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LISESAPAHVRGRAVVLLESFWAGGWLISALISYFIIPSWGWRIAVFITSLAALYALVLR
HHHCCCCCCCCCHHEEEHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FSIREADSNHSFTPKARLALRLKNIWSRPYAKATLMLWIVWFMVVFSYYGMFLWLPSVMV
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKGYSIVHSFGYVLIMTVAQLPGYFMAAWLIERWGRKWTLMVFLFGTAVSAIAFGFAQGL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MMLLLAGILLSFFNLGAWGALYAYSPEQYPEEIRGTGSGLAAGIGRIGGIVGPLLVGFLT
HHHHHHHHHHHHHHCCCCHHHEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKGVALSTTFIIFFISIMIAVIAIGFLGKETMEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure
MNGISNYKKLLAASGVAWLFDAMDVGILSFVIAALTSEWHLTESQVGMIGSISSLGMAVG
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AILFGALADRYNRKTILIISLLIFSIFNGISAFTTTYAAFVMIRFIVGCGLGGELPVAST
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LISESAPAHVRGRAVVLLESFWAGGWLISALISYFIIPSWGWRIAVFITSLAALYALVLR
HHHCCCCCCCCCHHEEEHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FSIREADSNHSFTPKARLALRLKNIWSRPYAKATLMLWIVWFMVVFSYYGMFLWLPSVMV
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKGYSIVHSFGYVLIMTVAQLPGYFMAAWLIERWGRKWTLMVFLFGTAVSAIAFGFAQGL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MMLLLAGILLSFFNLGAWGALYAYSPEQYPEEIRGTGSGLAAGIGRIGGIVGPLLVGFLT
HHHHHHHHHHHHHHCCCCHHHEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKGVALSTTFIIFFISIMIAVIAIGFLGKETMEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]