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The map label for this gene is galE [H]

Identifier: 116492015

GI number: 116492015

Start: 246687

End: 247691

Strand: Direct

Name: galE [H]

Synonym: PEPE_0207

Alternate gene names: 116492015

Gene position: 246687-247691 (Clockwise)

Preceding gene: 116492014

Following gene: 116492016

Centisome position: 13.46

GC content: 42.59

Gene sequence:

>1005_bases
ATGGCGGTCTTAGTTTTAGGTGGTGCCGGTTATATCGGCTCCCATGCAGTTGATCGATTAATTACGAAAGGTTACGATGT
AGCGGTTGTTGATAACTTGGTTACTGGACACCGCGCAGCCGTAAACCAGCAAGCTCGTTTTTACGAAGGTGATGTACGAG
ATGCTGAATTTATGGATTCAGTCTTCACCAAAGAAAACGTAGAAGGGGTAATTCATTTTGCTGCGTTTTCCGTGGTCCCT
GAATCAATGAAAAATCCTTTGAAGTATTTTGATAATAATACTGCTGGGATGGTTAAACTTCTTGAAGTAATGGCTAAACA
TGATGTGAAACGGATTGTATTTTCATCTACAGCGGCTACTTATGGCGAACCAGAACGGGTGCCAATTCAAGAATCTGATC
CACAAGTTCCAACTAATCCATATGGTGAAAGTAAGTTAGCAATGGAAAAAATCATGCATTGGTCAGATGTGGCTGATGGC
ATTAAGTTTGTGGCTTTGCGCTACTTTAACGTTGCTGGTGCCAAACCAGATGGCAGTATTGGGGAAGATCATCAACCAGA
AACACACTTAGTACCTATTATCTTACAAGTGGCTGCTGGTGAACGGGATCAGTTGCAAATTTTTGGGGATGACTATCCTA
CTGCTGATGGTACTAATGTACGCGATTACGTCCACGTCGTTGATTTGGCTGATGCTCATATTTTAGCTCTAGAATATCTC
AAACAAGGTCATGATAGTAACGCATTCAATCTCGGATCTTCAACAGGCTTCTCCAATCGTCAAATGTTAGAAGCTGCTCG
GGAAGTGACAGGAAAGGAAATTCCAGCTGTTATGGCACCAAGACGAGCTGGCGACCCTAGTACTTTAATCGCAGCGAGTG
ATAAAGCACGTGAAATTTTAGGTTGGCAACCTCAATATGATGATGTTAAGGAAATTATCAAAACTGCTTGGAATTGGAAA
GTCAACCATCCAGCTGGATACGATGACCGAGGAGGACAAGCCTAA

Upstream 100 bases:

>100_bases
ATTTCTATATTGCTGAAATTGCTGATGGACCTAAAGAACTTTAATATTAGTGAAAATTTTTAAATAGTAATACGCATTGA
GAGATTGAGGAGGAATTAGA

Downstream 100 bases:

>100_bases
TGAGTAGCTTAGAACAATTTGTCCAAGTTGTAATCGATTCGCCATCACCATACACCAATTTAGACCGAATTTATGTGCAT
AATCGGATTTTAGGTTTAGT

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAVLVLGGAGYIGSHAVDRLITKGYDVAVVDNLVTGHRAAVNQQARFYEGDVRDAEFMDSVFTKENVEGVIHFAAFSVVP
ESMKNPLKYFDNNTAGMVKLLEVMAKHDVKRIVFSSTAATYGEPERVPIQESDPQVPTNPYGESKLAMEKIMHWSDVADG
IKFVALRYFNVAGAKPDGSIGEDHQPETHLVPIILQVAAGERDQLQIFGDDYPTADGTNVRDYVHVVDLADAHILALEYL
KQGHDSNAFNLGSSTGFSNRQMLEAAREVTGKEIPAVMAPRRAGDPSTLIAASDKAREILGWQPQYDDVKEIIKTAWNWK
VNHPAGYDDRGGQA

Sequences:

>Translated_334_residues
MAVLVLGGAGYIGSHAVDRLITKGYDVAVVDNLVTGHRAAVNQQARFYEGDVRDAEFMDSVFTKENVEGVIHFAAFSVVP
ESMKNPLKYFDNNTAGMVKLLEVMAKHDVKRIVFSSTAATYGEPERVPIQESDPQVPTNPYGESKLAMEKIMHWSDVADG
IKFVALRYFNVAGAKPDGSIGEDHQPETHLVPIILQVAAGERDQLQIFGDDYPTADGTNVRDYVHVVDLADAHILALEYL
KQGHDSNAFNLGSSTGFSNRQMLEAAREVTGKEIPAVMAPRRAGDPSTLIAASDKAREILGWQPQYDDVKEIIKTAWNWK
VNHPAGYDDRGGQA
>Mature_333_residues
AVLVLGGAGYIGSHAVDRLITKGYDVAVVDNLVTGHRAAVNQQARFYEGDVRDAEFMDSVFTKENVEGVIHFAAFSVVPE
SMKNPLKYFDNNTAGMVKLLEVMAKHDVKRIVFSSTAATYGEPERVPIQESDPQVPTNPYGESKLAMEKIMHWSDVADGI
KFVALRYFNVAGAKPDGSIGEDHQPETHLVPIILQVAAGERDQLQIFGDDYPTADGTNVRDYVHVVDLADAHILALEYLK
QGHDSNAFNLGSSTGFSNRQMLEAAREVTGKEIPAVMAPRRAGDPSTLIAASDKAREILGWQPQYDDVKEIIKTAWNWKV
NHPAGYDDRGGQA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=41.0557184750733, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=41.0557184750733, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=41.0557184750733, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=26.4516129032258, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7657641, Length=333, Percent_Identity=24.9249249249249, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI193211614, Length=241, Percent_Identity=24.896265560166, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI8393516, Length=241, Percent_Identity=24.896265560166, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=40.7624633431085, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI48994969, Length=336, Percent_Identity=27.6785714285714, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=25.3687315634218, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790049, Length=256, Percent_Identity=30.078125, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=37.9310344827586, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=37.7142857142857, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17539532, Length=319, Percent_Identity=26.3322884012539, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17568069, Length=329, Percent_Identity=26.4437689969605, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=350, Percent_Identity=42.5714285714286, Blast_Score=264, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6321437, Length=256, Percent_Identity=25.78125, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19923002, Length=348, Percent_Identity=39.0804597701149, Blast_Score=248, Evalue=4e-66,
Organism=Drosophila melanogaster, GI21356223, Length=313, Percent_Identity=25.8785942492013, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36643; Mature: 36511

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVLGGAGYIGSHAVDRLITKGYDVAVVDNLVTGHRAAVNQQARFYEGDVRDAEFMDS
CEEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHHCHHHHHCCCHHHHCCCCCHHHHHHH
VFTKENVEGVIHFAAFSVVPESMKNPLKYFDNNTAGMVKLLEVMAKHDVKRIVFSSTAAT
HHHHHHHHHHHHHHHHHHCHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHC
YGEPERVPIQESDPQVPTNPYGESKLAMEKIMHWSDVADGIKFVALRYFNVAGAKPDGSI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GEDHQPETHLVPIILQVAAGERDQLQIFGDDYPTADGTNVRDYVHVVDLADAHILALEYL
CCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
KQGHDSNAFNLGSSTGFSNRQMLEAAREVTGKEIPAVMAPRRAGDPSTLIAASDKAREIL
HCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEECCHHHHHHH
GWQPQYDDVKEIIKTAWNWKVNHPAGYDDRGGQA
CCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
AVLVLGGAGYIGSHAVDRLITKGYDVAVVDNLVTGHRAAVNQQARFYEGDVRDAEFMDS
EEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHHCHHHHHCCCHHHHCCCCCHHHHHHH
VFTKENVEGVIHFAAFSVVPESMKNPLKYFDNNTAGMVKLLEVMAKHDVKRIVFSSTAAT
HHHHHHHHHHHHHHHHHHCHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHC
YGEPERVPIQESDPQVPTNPYGESKLAMEKIMHWSDVADGIKFVALRYFNVAGAKPDGSI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GEDHQPETHLVPIILQVAAGERDQLQIFGDDYPTADGTNVRDYVHVVDLADAHILALEYL
CCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
KQGHDSNAFNLGSSTGFSNRQMLEAAREVTGKEIPAVMAPRRAGDPSTLIAASDKAREIL
HCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEECCHHHHHHH
GWQPQYDDVKEIIKTAWNWKVNHPAGYDDRGGQA
CCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]