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The map label for this gene is dcuD [H]

Identifier: 116491974

GI number: 116491974

Start: 189260

End: 190663

Strand: Reverse

Name: dcuD [H]

Synonym: PEPE_0160

Alternate gene names: 116491974

Gene position: 190663-189260 (Counterclockwise)

Preceding gene: 116491975

Following gene: 116491973

Centisome position: 10.41

GC content: 33.62

Gene sequence:

>1404_bases
ATGCACGCAGTATTAATCTCTATCATTGGTATTATAGCTATAAGCATCTTGATTTATATGTTATTAAAGAAAAATGATAT
TAAAATGATACTTTTATCACTAGGTTTAATTTTGATGTACATCGCTATATTGTTGGGTAATGAGCTAAAGGTAACGCAAC
CTACTGGTACAAATTTATTAAATCCATTTCAGGCAATTGTTGATCAATTTTCATCAACTTTAGTAGGACCAGGATTTGTT
ATTTTAATTTTAGGTGGTTATAGCGCTTATATGAACCACATAGGTGCTAATCAAGTTACCGTACATGCACTTACCAAACC
GATCACTAAAATTAAATCTATTTATTTACTAGCTCCCATTGTTTTTCTTATTGGAAACCTATTATCACTTGTAATTCCAA
GTGCTTCAAATCTAGCAATTATTCTCCTTGCAACTCTATATCCCGTATTGCGTTCTGCAGGCATGTCGCGACTAACATCA
GCAGCTATCATCGGAACTTCAGCTACAATAGTTCCAACTCCCTTAGGTGCAGATAACGTAGCTATTGCATCCCAATTTCA
CATGTCTGTAACAGATTATGTTTTTCAAAAACACGCTTTAATTTCTATTCCAACCTTGCTAGCTATTACTATAGTTCATT
ATTTATGGCAAAAATATCAAGACAAAAAGCATCCTGAAGAGTTGTCATATTCTTCAGAGCTTTCTCAAAATAAAGAACAG
GATTCAACAGCGTCACCTAAGGTAAGTTATAAAGGATTCAAAGCTTTTATTTATGGATTACTACCGCTCTTACCTATTGT
AATATTACTAATCATCTTTTTCACCAATATATTTCTTCACACTAAGCTGAATATTAGTGTTCAATTAGTTAGCTTACTTA
GTTTTGTTATTGCTGTACTTGTAGAAATTTTTAATAAAAAGCATCCCCAAATTGTTTTAAAAGAAACTAGTAATTTTTTT
GAAGGTATGGGTAGCGTAATGAGTATCGTAGCATTACTAGTTTCCGCCCAAGTATTCGTACAAGGACTAACTTCGATAGG
GATAATTGATTTAATTCAAAAAACTATGCAAACTATGAATAGCTCAGGTATTGTTTTACCAGTAGTTATGGTTGTATTCA
CGGCAATTATTGTCTTATTAAGTGGAAGTGGAACTGCGTTACTTTATGCAATGATTCCTCTGTTATTACCATTATCTAAA
GCTGCAGGTATTTCCCCTATCGCCCTATCAGTACCTATGCAATTAGCAGGGAACTTATTGCGAGCAATCTCTCCTGTAGC
GGCAGTTATTTTAATAGTTGCTGGAACCACAAAGTTATCTCCAGTAAAAATTGTTAAACGCACTTCCGTTCCAATGGTTT
TTGGAGTAATCATGATGCTTGTTATGTCCCTACTAATCTTTTAG

Upstream 100 bases:

>100_bases
GGGAAAATTCCAATGCAGAGGTGGCAATTAACGTTGATACTAAACAATTTGAAGACTGGTTCACTAAAATGATATCAAAA
ACAATATAGGAGGCGATCTC

Downstream 100 bases:

>100_bases
GAGTACATCCATGCTTAAATCTATTGAACTTCAACCAGCTTATAAAGAGGACTTACCTCTATTACTCAATCTTTTACAAG
ATGCAAAAGAACAAATGGCT

Product: C4-dicarboxylate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MHAVLISIIGIIAISILIYMLLKKNDIKMILLSLGLILMYIAILLGNELKVTQPTGTNLLNPFQAIVDQFSSTLVGPGFV
ILILGGYSAYMNHIGANQVTVHALTKPITKIKSIYLLAPIVFLIGNLLSLVIPSASNLAIILLATLYPVLRSAGMSRLTS
AAIIGTSATIVPTPLGADNVAIASQFHMSVTDYVFQKHALISIPTLLAITIVHYLWQKYQDKKHPEELSYSSELSQNKEQ
DSTASPKVSYKGFKAFIYGLLPLLPIVILLIIFFTNIFLHTKLNISVQLVSLLSFVIAVLVEIFNKKHPQIVLKETSNFF
EGMGSVMSIVALLVSAQVFVQGLTSIGIIDLIQKTMQTMNSSGIVLPVVMVVFTAIIVLLSGSGTALLYAMIPLLLPLSK
AAGISPIALSVPMQLAGNLLRAISPVAAVILIVAGTTKLSPVKIVKRTSVPMVFGVIMMLVMSLLIF

Sequences:

>Translated_467_residues
MHAVLISIIGIIAISILIYMLLKKNDIKMILLSLGLILMYIAILLGNELKVTQPTGTNLLNPFQAIVDQFSSTLVGPGFV
ILILGGYSAYMNHIGANQVTVHALTKPITKIKSIYLLAPIVFLIGNLLSLVIPSASNLAIILLATLYPVLRSAGMSRLTS
AAIIGTSATIVPTPLGADNVAIASQFHMSVTDYVFQKHALISIPTLLAITIVHYLWQKYQDKKHPEELSYSSELSQNKEQ
DSTASPKVSYKGFKAFIYGLLPLLPIVILLIIFFTNIFLHTKLNISVQLVSLLSFVIAVLVEIFNKKHPQIVLKETSNFF
EGMGSVMSIVALLVSAQVFVQGLTSIGIIDLIQKTMQTMNSSGIVLPVVMVVFTAIIVLLSGSGTALLYAMIPLLLPLSK
AAGISPIALSVPMQLAGNLLRAISPVAAVILIVAGTTKLSPVKIVKRTSVPMVFGVIMMLVMSLLIF
>Mature_467_residues
MHAVLISIIGIIAISILIYMLLKKNDIKMILLSLGLILMYIAILLGNELKVTQPTGTNLLNPFQAIVDQFSSTLVGPGFV
ILILGGYSAYMNHIGANQVTVHALTKPITKIKSIYLLAPIVFLIGNLLSLVIPSASNLAIILLATLYPVLRSAGMSRLTS
AAIIGTSATIVPTPLGADNVAIASQFHMSVTDYVFQKHALISIPTLLAITIVHYLWQKYQDKKHPEELSYSSELSQNKEQ
DSTASPKVSYKGFKAFIYGLLPLLPIVILLIIFFTNIFLHTKLNISVQLVSLLSFVIAVLVEIFNKKHPQIVLKETSNFF
EGMGSVMSIVALLVSAQVFVQGLTSIGIIDLIQKTMQTMNSSGIVLPVVMVVFTAIIVLLSGSGTALLYAMIPLLLPLSK
AAGISPIALSVPMQLAGNLLRAISPVAAVILIVAGTTKLSPVKIVKRTSVPMVFGVIMMLVMSLLIF

Specific function: May have a role in the transport of dicarboxylates from the periplasm across the inner membrane. Seems not to be essential for growth. It is likely to be a cryptic gene, as no or low expression has been found under a number of growth conditions and when t

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1789622, Length=472, Percent_Identity=28.1779661016949, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1786839, Length=377, Percent_Identity=36.0742705570292, Blast_Score=176, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 50311; Mature: 50311

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAVLISIIGIIAISILIYMLLKKNDIKMILLSLGLILMYIAILLGNELKVTQPTGTNLL
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
NPFQAIVDQFSSTLVGPGFVILILGGYSAYMNHIGANQVTVHALTKPITKIKSIYLLAPI
CHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHH
VFLIGNLLSLVIPSASNLAIILLATLYPVLRSAGMSRLTSAAIIGTSATIVPTPLGADNV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCH
AIASQFHMSVTDYVFQKHALISIPTLLAITIVHYLWQKYQDKKHPEELSYSSELSQNKEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHCCCCC
DSTASPKVSYKGFKAFIYGLLPLLPIVILLIIFFTNIFLHTKLNISVQLVSLLSFVIAVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
VEIFNKKHPQIVLKETSNFFEGMGSVMSIVALLVSAQVFVQGLTSIGIIDLIQKTMQTMN
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSGIVLPVVMVVFTAIIVLLSGSGTALLYAMIPLLLPLSKAAGISPIALSVPMQLAGNLL
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHH
RAISPVAAVILIVAGTTKLSPVKIVKRTSVPMVFGVIMMLVMSLLIF
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHAVLISIIGIIAISILIYMLLKKNDIKMILLSLGLILMYIAILLGNELKVTQPTGTNLL
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
NPFQAIVDQFSSTLVGPGFVILILGGYSAYMNHIGANQVTVHALTKPITKIKSIYLLAPI
CHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHH
VFLIGNLLSLVIPSASNLAIILLATLYPVLRSAGMSRLTSAAIIGTSATIVPTPLGADNV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCH
AIASQFHMSVTDYVFQKHALISIPTLLAITIVHYLWQKYQDKKHPEELSYSSELSQNKEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHCCCCC
DSTASPKVSYKGFKAFIYGLLPLLPIVILLIIFFTNIFLHTKLNISVQLVSLLSFVIAVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
VEIFNKKHPQIVLKETSNFFEGMGSVMSIVALLVSAQVFVQGLTSIGIIDLIQKTMQTMN
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSGIVLPVVMVVFTAIIVLLSGSGTALLYAMIPLLLPLSKAAGISPIALSVPMQLAGNLL
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHH
RAISPVAAVILIVAGTTKLSPVKIVKRTSVPMVFGVIMMLVMSLLIF
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]