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The map label for this gene is argG

Identifier: 116514977

GI number: 116514977

Start: 34426

End: 35625

Strand: Direct

Name: argG

Synonym: BCc_032

Alternate gene names: 116514977

Gene position: 34426-35625 (Clockwise)

Preceding gene: 116514976

Following gene: 116514978

Centisome position: 8.27

GC content: 26.42

Gene sequence:

>1200_bases
ATGAAAAAAACTATTGTTTTAGCTTATTCAGGTGGTTTAGATACATCTGCTATTATACCTTGGATAAAAGATAATTATAA
TTTTGATGTTGTAGCTTTTGTAGCAGATATTGGTCAATCAAAAAAAGATTTGTATAAAATTAAAGAAAAAGCAATTATTT
CTGGTGCTTCTGATTGTTATATTTCGGACTTAAAAGATATTTTTGTAAAAAAATATGTTTTTCCTATGTTAAAAACTGGA
GCTATTTATGAAGGAGAATATTTATTAGGCACAGCTATAGCACGTCCTTTAATTGCTAAAGCACAAGTAGATTATGCTAA
AAAAATTAATGCAATAGGATTGTGTCATGGATCTACAGGAAAAGGGAATGATCAAGTTCGGTTTGAATTAGCTTATTCAG
CATTAGCACCTTCTTTATTAGTAATTGCCCCTTGGAGAGAATGGAAATTTCAATCTAGAGAAGATTTATTAAAATATTTA
AAAACAAAAAATATTGTTACAAATGTAAATAAGAAGAAAATTTATAGTAGAGATGAAAATATATTTCATGTATCTACGGA
AGGTGGAATTTTAGAAGATCCTTGGAATCCTGCTAATGAAGATTGTTGGTTTTGGACAAAAAGTCCTTTAAACGCTCCTA
ATAAACCTAAAAAAATATCTTTAAAAATTGAAAAAGGTTGTGTTGTTTCTATAAACAATAAATTTTTTAATGAATTTAAT
TGTTTAAAGAGATTAAATAAAATAGGTGCAAAACATTCTATTGGTAGAATTGATATTGTTGAAAATCGTCTTATTGGAAT
GAAATCTAGGGGATGTTATGAAACACCAGGTGGAACAATTATTTACAAAGCTTTAAGATCTTTAGAGCAATTAGTATTTG
ATAGAGAATGTATGTATTGGAAAAATAAGATTGCTTTACAATTATCTTCGATTATTTATGATGGAAAATGGTTTACCCCA
ATTCGTAAATCTCTTCAAAAATCTTCTGATATATTATCAAGTAGTATATCTGGAAAAGTAGTAGTAGAATTGTATAAAGG
ATCGGTAAGAATATTACAAAAAAAATCATTAAATTCTTTATATTCAAAAAAATATGTTACTTTTGGAAAAGATAATGTAT
ATAATCAAATAGACGCAAAAGGTTTTATTCGTTTGTTTTCTCTATCATCTCGTATTCGAGCATTAAAAAATAAAAAATAA

Upstream 100 bases:

>100_bases
GGTTGGCATTATTCAGAAGATTTATTTAATTTATTTAATAATAAGTCTATTGGTACAAAAATTTATGAGTAAAGATAATA
TACAGGATAGGTTTTAAAAT

Downstream 100 bases:

>100_bases
TACATAATTATATATTTTTTTGAGGTAAATATATGTCTTTATGGGGTGGAAGATTTACAAAAATCTCTAATACTGAATTT
GATAGTTTTAATAATTCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Citrulline--aspartate ligase

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKKTIVLAYSGGLDTSAIIPWIKDNYNFDVVAFVADIGQSKKDLYKIKEKAIISGASDCYISDLKDIFVKKYVFPMLKTG
AIYEGEYLLGTAIARPLIAKAQVDYAKKINAIGLCHGSTGKGNDQVRFELAYSALAPSLLVIAPWREWKFQSREDLLKYL
KTKNIVTNVNKKKIYSRDENIFHVSTEGGILEDPWNPANEDCWFWTKSPLNAPNKPKKISLKIEKGCVVSINNKFFNEFN
CLKRLNKIGAKHSIGRIDIVENRLIGMKSRGCYETPGGTIIYKALRSLEQLVFDRECMYWKNKIALQLSSIIYDGKWFTP
IRKSLQKSSDILSSSISGKVVVELYKGSVRILQKKSLNSLYSKKYVTFGKDNVYNQIDAKGFIRLFSLSSRIRALKNKK

Sequences:

>Translated_399_residues
MKKTIVLAYSGGLDTSAIIPWIKDNYNFDVVAFVADIGQSKKDLYKIKEKAIISGASDCYISDLKDIFVKKYVFPMLKTG
AIYEGEYLLGTAIARPLIAKAQVDYAKKINAIGLCHGSTGKGNDQVRFELAYSALAPSLLVIAPWREWKFQSREDLLKYL
KTKNIVTNVNKKKIYSRDENIFHVSTEGGILEDPWNPANEDCWFWTKSPLNAPNKPKKISLKIEKGCVVSINNKFFNEFN
CLKRLNKIGAKHSIGRIDIVENRLIGMKSRGCYETPGGTIIYKALRSLEQLVFDRECMYWKNKIALQLSSIIYDGKWFTP
IRKSLQKSSDILSSSISGKVVVELYKGSVRILQKKSLNSLYSKKYVTFGKDNVYNQIDAKGFIRLFSLSSRIRALKNKK
>Mature_399_residues
MKKTIVLAYSGGLDTSAIIPWIKDNYNFDVVAFVADIGQSKKDLYKIKEKAIISGASDCYISDLKDIFVKKYVFPMLKTG
AIYEGEYLLGTAIARPLIAKAQVDYAKKINAIGLCHGSTGKGNDQVRFELAYSALAPSLLVIAPWREWKFQSREDLLKYL
KTKNIVTNVNKKKIYSRDENIFHVSTEGGILEDPWNPANEDCWFWTKSPLNAPNKPKKISLKIEKGCVVSINNKFFNEFN
CLKRLNKIGAKHSIGRIDIVENRLIGMKSRGCYETPGGTIIYKALRSLEQLVFDRECMYWKNKIALQLSSIIYDGKWFTP
IRKSLQKSSDILSSSISGKVVVELYKGSVRILQKKSLNSLYSKKYVTFGKDNVYNQIDAKGFIRLFSLSSRIRALKNKK

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI53759107, Length=400, Percent_Identity=42.75, Blast_Score=311, Evalue=8e-85,
Organism=Homo sapiens, GI16950633, Length=400, Percent_Identity=42.75, Blast_Score=311, Evalue=8e-85,
Organism=Escherichia coli, GI1789563, Length=412, Percent_Identity=28.3980582524272, Blast_Score=128, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324514, Length=403, Percent_Identity=39.9503722084367, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21358151, Length=409, Percent_Identity=39.8533007334963, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ASSY_BUCCC (Q058D6)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802606.1
- STRING:   Q058D6
- EnsemblBacteria:   EBBUCT00000001295
- GeneID:   4440707
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_032
- eggNOG:   COG0137
- GeneTree:   EBGT00050000008086
- HOGENOM:   HBG335267
- OMA:   PLIAKRQ
- BioCyc:   BAPH372461:BCC_032-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00005
- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11587
- TIGRFAMs:   TIGR00032

Pfam domain/function: PF00764 Arginosuc_synth

EC number: =6.3.4.5

Molecular weight: Translated: 45285; Mature: 45285

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1; PS00565 ARGININOSUCCIN_SYN_2

Important sites: BINDING 35-35 BINDING 87-87 BINDING 117-117 BINDING 119-119 BINDING 123-123 BINDING 123-123 BINDING 124-124 BINDING 127-127 BINDING 176-176 BINDING 185-185 BINDING 261-261 BINDING 273-273

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIVLAYSGGLDTSAIIPWIKDNYNFDVVAFVADIGQSKKDLYKIKEKAIISGASDCY
CCCEEEEEECCCCCCCEECCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHHHHCCCCCHH
ISDLKDIFVKKYVFPMLKTGAIYEGEYLLGTAIARPLIAKAQVDYAKKINAIGLCHGSTG
HHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
KGNDQVRFELAYSALAPSLLVIAPWREWKFQSREDLLKYLKTKNIVTNVNKKKIYSRDEN
CCCCCEEEEEEHHHHCCCEEEEECCHHCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCC
IFHVSTEGGILEDPWNPANEDCWFWTKSPLNAPNKPKKISLKIEKGCVVSINNKFFNEFN
EEEEECCCCEECCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCEEEEECHHHHHHHH
CLKRLNKIGAKHSIGRIDIVENRLIGMKSRGCYETPGGTIIYKALRSLEQLVFDRECMYW
HHHHHHHCCCCCCCCEEEEECCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
KNKIALQLSSIIYDGKWFTPIRKSLQKSSDILSSSISGKVVVELYKGSVRILQKKSLNSL
HHHHHEEEEHHEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
YSKKYVTFGKDNVYNQIDAKGFIRLFSLSSRIRALKNKK
HHCCCEECCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKTIVLAYSGGLDTSAIIPWIKDNYNFDVVAFVADIGQSKKDLYKIKEKAIISGASDCY
CCCEEEEEECCCCCCCEECCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHHHHCCCCCHH
ISDLKDIFVKKYVFPMLKTGAIYEGEYLLGTAIARPLIAKAQVDYAKKINAIGLCHGSTG
HHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
KGNDQVRFELAYSALAPSLLVIAPWREWKFQSREDLLKYLKTKNIVTNVNKKKIYSRDEN
CCCCCEEEEEEHHHHCCCEEEEECCHHCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCC
IFHVSTEGGILEDPWNPANEDCWFWTKSPLNAPNKPKKISLKIEKGCVVSINNKFFNEFN
EEEEECCCCEECCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCEEEEECHHHHHHHH
CLKRLNKIGAKHSIGRIDIVENRLIGMKSRGCYETPGGTIIYKALRSLEQLVFDRECMYW
HHHHHHHCCCCCCCCEEEEECCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
KNKIALQLSSIIYDGKWFTPIRKSLQKSSDILSSSISGKVVVELYKGSVRILQKKSLNSL
HHHHHEEEEHHEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
YSKKYVTFGKDNVYNQIDAKGFIRLFSLSSRIRALKNKK
HHCCCEECCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA