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The map label for this gene is kamA [H]

Identifier: 116332642

GI number: 116332642

Start: 254913

End: 256025

Strand: Direct

Name: kamA [H]

Synonym: LBJ_4222

Alternate gene names: 116332642

Gene position: 254913-256025 (Clockwise)

Preceding gene: 116332641

Following gene: 116332643

Centisome position: 85.04

GC content: 41.6

Gene sequence:

>1113_bases
ATGCCCAGTTCCACTTTTTATCCATCTCCATCCGATTTAGAAACTTCTTCGGAGTGGTTACGTTGGAAATGGCAGATTCA
AAATAGAATCAAAACACAAACGCAGTTATCCGAACATATCGAACTTACTGAAAAAGAAACCCTCTCCTTCGAAGCCTGTT
CCGAGTTTTTCGAATTTTCCGTTACACCCTATTATTTAAATCTCGCGGATACAAAAGATCCGAATTGTCCGATCCGGCTC
CAGATTGTTCCACATCAGGGGGAATTGACCCGAAACAGTTTTGAAAGACAAGATCCTCTTGCGGAAGAAGCCCACATGCC
TGTGAAAGGAGTTACGCACAGATATCCGGATCGTGCACTTTGGTATCTATCGCATGTATGCGCGGTTTATTGCAGATTCT
GCACCCGCAAAAGAAAGGTCAGTAAATCCGTACATACACCCGGTAAGGAAGAATGGGATCAGGCTCTGATTTATTTTCGA
TCGCACAAAGAAATCAAGGAAGTGATTCTTTCCGGAGGAGATCCTCTTAATCTTTCCGATGAAAAACTGGATTATCTTCT
GGGAGAATTAAAATCCATTTCGCATATCAATCAAGTGAGAATCCATTCCAGATATCCGGTTACACTTCCGATGAGAATCG
ATTCTTCGTTATGCTCCGTTTTTAAAAAACATTTCCCAATCTATTTGGTCACCCATTTCAATCATCCGAAAGAGATCACC
CCTCTCGTTCGGGAAAGAATTTCCCTTTTGATCCAAGAAGGGAATGTGATAGTTTTAAATCAAAGCGTCCTTTTAAAGGG
AATCAACGATTCAGCCGAAACGTTAAAAAAGCTCTTCTATGGATTAACCGCCATCGGAATCAAACCTTATTATCTGCATC
AGTGCGACGAGGTTTGGGGAAGCGGAGATTTTCGAGTCGAAATTGAAAGAGGGGTAGAGATTATGAAACAGATTCGAGGA
AGGATTTCCGGTTTATCGGTTCCGTTATACGTAGTGGATTTAACCGGAGGTGGAGGTAAGGTCCCACTTCCAACTTTTTA
TCTGGCGGGAAAAACGGATCGTTCTTACATCTTTCGAAATTATCAGGACGAACTTTATGAAATCAGTTATTAA

Upstream 100 bases:

>100_bases
ATTATGTAAAGATGAGTAAAGCCTGACCCTTGATATATAATTGACTCCCCGAGCGATGATAGGAGGATTTTAGTAGAACC
AAATCCGGAGTCGATTTTTT

Downstream 100 bases:

>100_bases
ATTCGAGAATAGTCCTATTATTTGGAAACTTTTTCCCAAAATCGTTCTATGCCTGGCATTCGGATTTCTTACCGTCTGCA
AAACCCCGGAAAGTAAAAGA

Product: lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MPSSTFYPSPSDLETSSEWLRWKWQIQNRIKTQTQLSEHIELTEKETLSFEACSEFFEFSVTPYYLNLADTKDPNCPIRL
QIVPHQGELTRNSFERQDPLAEEAHMPVKGVTHRYPDRALWYLSHVCAVYCRFCTRKRKVSKSVHTPGKEEWDQALIYFR
SHKEIKEVILSGGDPLNLSDEKLDYLLGELKSISHINQVRIHSRYPVTLPMRIDSSLCSVFKKHFPIYLVTHFNHPKEIT
PLVRERISLLIQEGNVIVLNQSVLLKGINDSAETLKKLFYGLTAIGIKPYYLHQCDEVWGSGDFRVEIERGVEIMKQIRG
RISGLSVPLYVVDLTGGGGKVPLPTFYLAGKTDRSYIFRNYQDELYEISY

Sequences:

>Translated_370_residues
MPSSTFYPSPSDLETSSEWLRWKWQIQNRIKTQTQLSEHIELTEKETLSFEACSEFFEFSVTPYYLNLADTKDPNCPIRL
QIVPHQGELTRNSFERQDPLAEEAHMPVKGVTHRYPDRALWYLSHVCAVYCRFCTRKRKVSKSVHTPGKEEWDQALIYFR
SHKEIKEVILSGGDPLNLSDEKLDYLLGELKSISHINQVRIHSRYPVTLPMRIDSSLCSVFKKHFPIYLVTHFNHPKEIT
PLVRERISLLIQEGNVIVLNQSVLLKGINDSAETLKKLFYGLTAIGIKPYYLHQCDEVWGSGDFRVEIERGVEIMKQIRG
RISGLSVPLYVVDLTGGGGKVPLPTFYLAGKTDRSYIFRNYQDELYEISY
>Mature_369_residues
PSSTFYPSPSDLETSSEWLRWKWQIQNRIKTQTQLSEHIELTEKETLSFEACSEFFEFSVTPYYLNLADTKDPNCPIRLQ
IVPHQGELTRNSFERQDPLAEEAHMPVKGVTHRYPDRALWYLSHVCAVYCRFCTRKRKVSKSVHTPGKEEWDQALIYFRS
HKEIKEVILSGGDPLNLSDEKLDYLLGELKSISHINQVRIHSRYPVTLPMRIDSSLCSVFKKHFPIYLVTHFNHPKEITP
LVRERISLLIQEGNVIVLNQSVLLKGINDSAETLKKLFYGLTAIGIKPYYLHQCDEVWGSGDFRVEIERGVEIMKQIRGR
ISGLSVPLYVVDLTGGGGKVPLPTFYLAGKTDRSYIFRNYQDELYEISY

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=324, Percent_Identity=35.1851851851852, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 42840; Mature: 42708

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSTFYPSPSDLETSSEWLRWKWQIQNRIKTQTQLSEHIELTEKETLSFEACSEFFEFS
CCCCCCCCCCCCCCCCHHHHEEHEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
VTPYYLNLADTKDPNCPIRLQIVPHQGELTRNSFERQDPLAEEAHMPVKGVTHRYPDRAL
CCEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCHHHH
WYLSHVCAVYCRFCTRKRKVSKSVHTPGKEEWDQALIYFRSHKEIKEVILSGGDPLNLSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
EKLDYLLGELKSISHINQVRIHSRYPVTLPMRIDSSLCSVFKKHFPIYLVTHFNHPKEIT
HHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCHHHH
PLVRERISLLIQEGNVIVLNQSVLLKGINDSAETLKKLFYGLTAIGIKPYYLHQCDEVWG
HHHHHHHHHEEECCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
SGDFRVEIERGVEIMKQIRGRISGLSVPLYVVDLTGGGGKVPLPTFYLAGKTDRSYIFRN
CCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHC
YQDELYEISY
CCHHHEECCC
>Mature Secondary Structure 
PSSTFYPSPSDLETSSEWLRWKWQIQNRIKTQTQLSEHIELTEKETLSFEACSEFFEFS
CCCCCCCCCCCCCCCHHHHEEHEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
VTPYYLNLADTKDPNCPIRLQIVPHQGELTRNSFERQDPLAEEAHMPVKGVTHRYPDRAL
CCEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCHHHH
WYLSHVCAVYCRFCTRKRKVSKSVHTPGKEEWDQALIYFRSHKEIKEVILSGGDPLNLSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
EKLDYLLGELKSISHINQVRIHSRYPVTLPMRIDSSLCSVFKKHFPIYLVTHFNHPKEIT
HHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCHHHH
PLVRERISLLIQEGNVIVLNQSVLLKGINDSAETLKKLFYGLTAIGIKPYYLHQCDEVWG
HHHHHHHHHEEECCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
SGDFRVEIERGVEIMKQIRGRISGLSVPLYVVDLTGGGGKVPLPTFYLAGKTDRSYIFRN
CCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHC
YQDELYEISY
CCHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]