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The map label for this gene is degP [C]

Identifier: 116332597

GI number: 116332597

Start: 195891

End: 197399

Strand: Reverse

Name: degP [C]

Synonym: LBJ_4169

Alternate gene names: 116332597

Gene position: 197399-195891 (Counterclockwise)

Preceding gene: 116332598

Following gene: 116332596

Centisome position: 65.85

GC content: 41.88

Gene sequence:

>1509_bases
TTGACGGCTATAGTATCTGGTTTTTTGGGGATCCGAATCGGTTTGAAATGTACGGTTCGTTTTTTTTCGCTTGGGTTGCT
TTTTTGCATCCAGACTAAGATTTATTCCATTGAAAATCCTCTTTCTTTTGATGAACTCCGTAAAGGAGTTGTACAGATCC
GGGTTTATTCCCAAGCGGTAAATCCGTTTTCTCCTTGGACGACCGATACGGTTCGAGCCGGTTCGGGAACAGGTTTTTTA
ATCGGAAATAAAAAAATTCTTACCAACGCACACGTGGTTTCTAATGCGAAATTCGTTCAGGTTCAGAGATACAATCAGAC
CGAATGGTACGGCGTAAAAATCCTACATCTCGCGCACGATTGTGATTTGGCGGTTTTGGAAGCTGAAAGCCCCGACTTCT
ACAAGGACTCGAGAGATTTACAACTCGGAGAAATTCCAGAGCTCAATTCTCCGTTGATTGTGGTCGGTTATCCGATCGGA
GGGAATAAGGTTTCGGTTACAAGAGGAATCGTTTCCAGAAAGGATCAATCGGTTTATTCCCATTCCGCCGTCGACAGTCA
TTTAGTCTTACAAGTGGATGCGGCGATTAATCCAGGGAATTCCGGAGGTCCGGCGATTCAGGATGATAAGGTCGTAGGAG
TTGCGTTTCAGGTTGCGATCAAGGGTGAGAATATCGGATATCTTATTCCGACAAACGTTATACGTCATTTTTTAACGGAC
ATAGAAGACGGGAAATATGACGGATACGTGGAGCTTGGAGTGAGAACTTTGAATTCGTTTAATATTTCTTTGAGAAAGGC
CAAAGGAATTCCGGATCATTTGGAAGGAGTTTTTGTTTCTAGAGTTTTAAAAAATGGTTCTGCGGAAAATTATCTAAAGG
AAGGAGATTTTCTCACCGAAATAGACGGGCAACCGATCGGAAAAAACGGAACCGTTATGCAGGATAAAGACGCAAGAGTT
GACTTTGTCGAGATCGTGGATAATAAACACGCAGGAGACAAGATCTCTTTCAAACTGTATAGGGATGGAAAAGAAATGTC
TGTTTCTTTTCCGGCGCGTCGTATGTCTGATTTCGATTTTATGAGAAATCAATACGATAAACAGTATGATTTCGAAATGA
TCGGCGGACTTTTATTTCAAGAAATGTCCCGAGATTTGATCACGAGTTGGGGTCGTGGCGGCAACACTTCCGGAGGAAGT
CAGCTTTTATACAGATTTTTTTACTTCATAGAAGACGGGCTGAACCGGGCAAAAAAAACCGACGTGGTTTTATACCGGAA
ACTTTCTGATCCGATCAATTCTTCCGCGGAATATTTTGTGAACCTTGTTTTGGAATCCGTTAACGGGATTCCTGTTACGG
AATTGAACGATCTAAGAAAGATTTTAAAACAATCCAAGGATAAATATCTTCGTTTGAAATTTTTAGATATTCAGGTTCCT
CTCGTTTTGGACCGCGAGGAAGCTGAAAAGGCGGACGAAAAAATCCGTAAAATTTACGGCTTGGAGTAA

Upstream 100 bases:

>100_bases
TGGAAGTAAGAAACTTCAGGAAAAGCTTGAGGTTCCGGTTTTCGCGATTTGCGAATTCGAAGGACATTAGAAAATTCTAA
AATTCTTTTTGGAGGATTCA

Downstream 100 bases:

>100_bases
TTAAGGAAATTATAATGTTAAAAATCTGTATCATACCGATATTTATCTGTTTTTCGTTGGGGGTTTTTGCGGAGAAGGTA
GAGTCAGATCGTGTTCTCAT

Product: trypsin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MTAIVSGFLGIRIGLKCTVRFFSLGLLFCIQTKIYSIENPLSFDELRKGVVQIRVYSQAVNPFSPWTTDTVRAGSGTGFL
IGNKKILTNAHVVSNAKFVQVQRYNQTEWYGVKILHLAHDCDLAVLEAESPDFYKDSRDLQLGEIPELNSPLIVVGYPIG
GNKVSVTRGIVSRKDQSVYSHSAVDSHLVLQVDAAINPGNSGGPAIQDDKVVGVAFQVAIKGENIGYLIPTNVIRHFLTD
IEDGKYDGYVELGVRTLNSFNISLRKAKGIPDHLEGVFVSRVLKNGSAENYLKEGDFLTEIDGQPIGKNGTVMQDKDARV
DFVEIVDNKHAGDKISFKLYRDGKEMSVSFPARRMSDFDFMRNQYDKQYDFEMIGGLLFQEMSRDLITSWGRGGNTSGGS
QLLYRFFYFIEDGLNRAKKTDVVLYRKLSDPINSSAEYFVNLVLESVNGIPVTELNDLRKILKQSKDKYLRLKFLDIQVP
LVLDREEAEKADEKIRKIYGLE

Sequences:

>Translated_502_residues
MTAIVSGFLGIRIGLKCTVRFFSLGLLFCIQTKIYSIENPLSFDELRKGVVQIRVYSQAVNPFSPWTTDTVRAGSGTGFL
IGNKKILTNAHVVSNAKFVQVQRYNQTEWYGVKILHLAHDCDLAVLEAESPDFYKDSRDLQLGEIPELNSPLIVVGYPIG
GNKVSVTRGIVSRKDQSVYSHSAVDSHLVLQVDAAINPGNSGGPAIQDDKVVGVAFQVAIKGENIGYLIPTNVIRHFLTD
IEDGKYDGYVELGVRTLNSFNISLRKAKGIPDHLEGVFVSRVLKNGSAENYLKEGDFLTEIDGQPIGKNGTVMQDKDARV
DFVEIVDNKHAGDKISFKLYRDGKEMSVSFPARRMSDFDFMRNQYDKQYDFEMIGGLLFQEMSRDLITSWGRGGNTSGGS
QLLYRFFYFIEDGLNRAKKTDVVLYRKLSDPINSSAEYFVNLVLESVNGIPVTELNDLRKILKQSKDKYLRLKFLDIQVP
LVLDREEAEKADEKIRKIYGLE
>Mature_501_residues
TAIVSGFLGIRIGLKCTVRFFSLGLLFCIQTKIYSIENPLSFDELRKGVVQIRVYSQAVNPFSPWTTDTVRAGSGTGFLI
GNKKILTNAHVVSNAKFVQVQRYNQTEWYGVKILHLAHDCDLAVLEAESPDFYKDSRDLQLGEIPELNSPLIVVGYPIGG
NKVSVTRGIVSRKDQSVYSHSAVDSHLVLQVDAAINPGNSGGPAIQDDKVVGVAFQVAIKGENIGYLIPTNVIRHFLTDI
EDGKYDGYVELGVRTLNSFNISLRKAKGIPDHLEGVFVSRVLKNGSAENYLKEGDFLTEIDGQPIGKNGTVMQDKDARVD
FVEIVDNKHAGDKISFKLYRDGKEMSVSFPARRMSDFDFMRNQYDKQYDFEMIGGLLFQEMSRDLITSWGRGGNTSGGSQ
LLYRFFYFIEDGLNRAKKTDVVLYRKLSDPINSSAEYFVNLVLESVNGIPVTELNDLRKILKQSKDKYLRLKFLDIQVPL
VLDREEAEKADEKIRKIYGLE

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=264, Percent_Identity=29.9242424242424, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4506141, Length=282, Percent_Identity=29.0780141843972, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI22129776, Length=284, Percent_Identity=26.4084507042254, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786356, Length=322, Percent_Identity=29.1925465838509, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789629, Length=291, Percent_Identity=27.8350515463918, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 56304; Mature: 56173

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIVSGFLGIRIGLKCTVRFFSLGLLFCIQTKIYSIENPLSFDELRKGVVQIRVYSQAV
CCHHHHCHHHEEECHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHCCCEEEEEEECCC
NPFSPWTTDTVRAGSGTGFLIGNKKILTNAHVVSNAKFVQVQRYNQTEWYGVKILHLAHD
CCCCCCCCCEEECCCCCEEEEECCEEEECCEEECCCEEEEEEECCCCCEEEEEEEEEECC
CDLAVLEAESPDFYKDSRDLQLGEIPELNSPLIVVGYPIGGNKVSVTRGIVSRKDQSVYS
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHCCCHHHHH
HSAVDSHLVLQVDAAINPGNSGGPAIQDDKVVGVAFQVAIKGENIGYLIPTNVIRHFLTD
HHCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCEEECCHHHHHHHHHC
IEDGKYDGYVELGVRTLNSFNISLRKAKGIPDHLEGVFVSRVLKNGSAENYLKEGDFLTE
CCCCCCCCEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEEE
IDGQPIGKNGTVMQDKDARVDFVEIVDNKHAGDKISFKLYRDGKEMSVSFPARRMSDFDF
CCCCCCCCCCCEECCCCCCEEEEEEECCCCCCCEEEEEEEECCCEEEEECCHHHHHHHHH
MRNQYDKQYDFEMIGGLLFQEMSRDLITSWGRGGNTSGGSQLLYRFFYFIEDGLNRAKKT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DVVLYRKLSDPINSSAEYFVNLVLESVNGIPVTELNDLRKILKQSKDKYLRLKFLDIQVP
CEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEE
LVLDREEAEKADEKIRKIYGLE
EEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAIVSGFLGIRIGLKCTVRFFSLGLLFCIQTKIYSIENPLSFDELRKGVVQIRVYSQAV
CHHHHCHHHEEECHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHCCCEEEEEEECCC
NPFSPWTTDTVRAGSGTGFLIGNKKILTNAHVVSNAKFVQVQRYNQTEWYGVKILHLAHD
CCCCCCCCCEEECCCCCEEEEECCEEEECCEEECCCEEEEEEECCCCCEEEEEEEEEECC
CDLAVLEAESPDFYKDSRDLQLGEIPELNSPLIVVGYPIGGNKVSVTRGIVSRKDQSVYS
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHCCCHHHHH
HSAVDSHLVLQVDAAINPGNSGGPAIQDDKVVGVAFQVAIKGENIGYLIPTNVIRHFLTD
HHCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCEEECCHHHHHHHHHC
IEDGKYDGYVELGVRTLNSFNISLRKAKGIPDHLEGVFVSRVLKNGSAENYLKEGDFLTE
CCCCCCCCEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEEE
IDGQPIGKNGTVMQDKDARVDFVEIVDNKHAGDKISFKLYRDGKEMSVSFPARRMSDFDF
CCCCCCCCCCCEECCCCCCEEEEEEECCCCCCCEEEEEEEECCCEEEEECCHHHHHHHHH
MRNQYDKQYDFEMIGGLLFQEMSRDLITSWGRGGNTSGGSQLLYRFFYFIEDGLNRAKKT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
DVVLYRKLSDPINSSAEYFVNLVLESVNGIPVTELNDLRKILKQSKDKYLRLKFLDIQVP
CEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEE
LVLDREEAEKADEKIRKIYGLE
EEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA