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The map label for this gene is cirA [H]

Identifier: 116332591

GI number: 116332591

Start: 185873

End: 187966

Strand: Direct

Name: cirA [H]

Synonym: LBJ_4163

Alternate gene names: 116332591

Gene position: 185873-187966 (Clockwise)

Preceding gene: 116332590

Following gene: 116332594

Centisome position: 62.01

GC content: 41.69

Gene sequence:

>2094_bases
ATGTTCTTTTCGATCCTTCGATTTAAATCGATTCAGATCCTATTTCCGATTTTCTTTTGTATCTCGATTCAAGCCCAAGA
TGAAAGCACAAAAATTGGAAACAAAGTCGTCGAGAAAGAATCACCTAACAAGATTATTACGAAAAATAACAACACAACCA
CCGAATCACTTCGAAAAGAAAACGGACAAAACATTCCAGAAGAATCCCAAATCGTAGTTACAGGTTCCAGAGGCGAACGA
AGACTCAAAGATTCCACGGTCGCGACCGAAGTAATCTCCCGTAAAAAAATAGAAGCTAGTGGTGCAAGAAACGCAGCCGA
AGTTTTAGAAACCCAATTGGGAATCGACGTAGTTCCGTTCTTTGGAGGTTCAAGAGTTCGAATGCTCGGTCTCGATTCGC
AATACGTTCTGATTCTAATTGACGGAGAAAGGATCGCAGGACGTTTAAACAATGCTGTGGACCTCAGCAGATTCAAAGTC
CAGAACTTAGAGAGAATCGAAATCGTAAAAGGCGCCTCATCGGCATTATACGGAGCAGACGCAATCGGAGGAGTCATCAA
CCTCATCACAAGAGAGGCGGATAAAAAACTAAGCTACGAAATGCGCACCACTTACGGCAACGGAAGTCGAAAGAATTTCA
ACACTGAAGGGGAATTCAATACAAATGCCAACATGGGTTTTAGAAACGAGTTCGTCAGCGGTTCTGTTTCCTCAGGTTAC
AATAAAAATCCGGGTTACAGATTGGTTCCGAATTCTCAGGCTACGACCGGAAACGCATATCAGGATTTAAACACAGGAAT
AAATCTCACCTTCAACCCAGACGGGAACTTCAAAGGTAAAACTAGAATTCTTTACCAACACAGGAATCAAAATGGTGTGG
ACGTGACTCAATCCAAAGCAATTTTTGACCGGAATAATAAAACGCACGATTTTTTAGCCACAGGCTCCTTGGAATACGGA
TTTGGAAAAAGAAATTTGATCTCCTTTCGAGGAAACATTTCCAAATGGGAAAACAAATACTACAACAATCAAAGAGGGTC
GGACGAACTAGACGTAAAACAATTGAACGCAGAACTCACTTCCCAAGGAACCGTTCAATTGGACATGGAAGCTTCCGAAA
GGCATTTTATCACGATAGGCGCCGAATCTTTTGCGAATGAATTAGAATCGGATCGGTTACAGAGTCGCTACGTATATAGA
ACTAGAAAGGCCGTATTCTTTCAGGACGAGTGGACCATCTCCAGTTCTCCCCGAATTCGAATGATTCCGGGAGTGAGATA
CGACGACGATTCTCAATTCGGCAATCAAACGACTCCTAAACTTGCCGTCCGTTACGATATTTTTCAGAACTTAGTTTGGA
GGGCGAGCTACGGAAGGGGTTTTCGTCCACCCAGCTTTCAGGAATTGTATCTTCGTTTTGAAAACCCGGCTGTGGGTTAC
GTAGTGGAAGGGAACCCGAATTTAAAACCGGAACGATCGATCACGATCAACTCAGACTTGGAATACAGTCCTTTTAGTTT
TTTGACACTTTCCCTCAGTTTATACCGCAACGACATTATCAATTTAATTCAGTACAAATTCGATTCAAACAAAGGGAAGG
AATTTGCCGAATTTCAATTACAAAACATCGCAAAGGCATATACGAGAGGAGGAGAATTCGGAGTTCAGTATAGATTTTTA
AAATACTTCACACTCGAATTGGGTTATAATCATACGGATACAAGAGATCTAAATACGGATAGACCTTTAGAAGGAAGAGC
TCTTCATCAGGCGTCTGCAAACTTCATCTATAATTCCCCTGGGGGGTTCCAATTCAACTTGAGAGGCAAACATCTGGATA
AAAGGCCGTTCTATAGTGCCACGAACAATCTGGCAGGACAAGATTCTATTCCCACCGAAGTTAAATTGAACGAAAATCCT
CCCGTGATTTACGGAAAACCGTTTTCGATTCTGAACGTAAGAATCGAACAGAAATTCTTCAATAAACACTTTTCTCTTTT
TTTAGGAGTGGATAACGTGCTCAATCAATACGAACTTACCTACAATCCAACCCGACCTCGATTTTATTACGGCGGATTTT
CCGCTCAGTTTTAA

Upstream 100 bases:

>100_bases
GGAAACGAATACTACCTCTTTCAGATCACCGGTTATTATAATTCCGAGGGAAGCTCAGCACATCCCACCGTAAGATGGAA
GCAAATCCCTTACTAACCGT

Downstream 100 bases:

>100_bases
ATTCCTTGTTCAAACATTCATAAGACACTTTTTCCGAAGATTTCATTGAACTTTCGAAACTACTACGAATTTGTCCCAAA
ACCTAAGAACCCATCTCAAA

Product: TonB-dependant outer membrane receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MFFSILRFKSIQILFPIFFCISIQAQDESTKIGNKVVEKESPNKIITKNNNTTTESLRKENGQNIPEESQIVVTGSRGER
RLKDSTVATEVISRKKIEASGARNAAEVLETQLGIDVVPFFGGSRVRMLGLDSQYVLILIDGERIAGRLNNAVDLSRFKV
QNLERIEIVKGASSALYGADAIGGVINLITREADKKLSYEMRTTYGNGSRKNFNTEGEFNTNANMGFRNEFVSGSVSSGY
NKNPGYRLVPNSQATTGNAYQDLNTGINLTFNPDGNFKGKTRILYQHRNQNGVDVTQSKAIFDRNNKTHDFLATGSLEYG
FGKRNLISFRGNISKWENKYYNNQRGSDELDVKQLNAELTSQGTVQLDMEASERHFITIGAESFANELESDRLQSRYVYR
TRKAVFFQDEWTISSSPRIRMIPGVRYDDDSQFGNQTTPKLAVRYDIFQNLVWRASYGRGFRPPSFQELYLRFENPAVGY
VVEGNPNLKPERSITINSDLEYSPFSFLTLSLSLYRNDIINLIQYKFDSNKGKEFAEFQLQNIAKAYTRGGEFGVQYRFL
KYFTLELGYNHTDTRDLNTDRPLEGRALHQASANFIYNSPGGFQFNLRGKHLDKRPFYSATNNLAGQDSIPTEVKLNENP
PVIYGKPFSILNVRIEQKFFNKHFSLFLGVDNVLNQYELTYNPTRPRFYYGGFSAQF

Sequences:

>Translated_697_residues
MFFSILRFKSIQILFPIFFCISIQAQDESTKIGNKVVEKESPNKIITKNNNTTTESLRKENGQNIPEESQIVVTGSRGER
RLKDSTVATEVISRKKIEASGARNAAEVLETQLGIDVVPFFGGSRVRMLGLDSQYVLILIDGERIAGRLNNAVDLSRFKV
QNLERIEIVKGASSALYGADAIGGVINLITREADKKLSYEMRTTYGNGSRKNFNTEGEFNTNANMGFRNEFVSGSVSSGY
NKNPGYRLVPNSQATTGNAYQDLNTGINLTFNPDGNFKGKTRILYQHRNQNGVDVTQSKAIFDRNNKTHDFLATGSLEYG
FGKRNLISFRGNISKWENKYYNNQRGSDELDVKQLNAELTSQGTVQLDMEASERHFITIGAESFANELESDRLQSRYVYR
TRKAVFFQDEWTISSSPRIRMIPGVRYDDDSQFGNQTTPKLAVRYDIFQNLVWRASYGRGFRPPSFQELYLRFENPAVGY
VVEGNPNLKPERSITINSDLEYSPFSFLTLSLSLYRNDIINLIQYKFDSNKGKEFAEFQLQNIAKAYTRGGEFGVQYRFL
KYFTLELGYNHTDTRDLNTDRPLEGRALHQASANFIYNSPGGFQFNLRGKHLDKRPFYSATNNLAGQDSIPTEVKLNENP
PVIYGKPFSILNVRIEQKFFNKHFSLFLGVDNVLNQYELTYNPTRPRFYYGGFSAQF
>Mature_697_residues
MFFSILRFKSIQILFPIFFCISIQAQDESTKIGNKVVEKESPNKIITKNNNTTTESLRKENGQNIPEESQIVVTGSRGER
RLKDSTVATEVISRKKIEASGARNAAEVLETQLGIDVVPFFGGSRVRMLGLDSQYVLILIDGERIAGRLNNAVDLSRFKV
QNLERIEIVKGASSALYGADAIGGVINLITREADKKLSYEMRTTYGNGSRKNFNTEGEFNTNANMGFRNEFVSGSVSSGY
NKNPGYRLVPNSQATTGNAYQDLNTGINLTFNPDGNFKGKTRILYQHRNQNGVDVTQSKAIFDRNNKTHDFLATGSLEYG
FGKRNLISFRGNISKWENKYYNNQRGSDELDVKQLNAELTSQGTVQLDMEASERHFITIGAESFANELESDRLQSRYVYR
TRKAVFFQDEWTISSSPRIRMIPGVRYDDDSQFGNQTTPKLAVRYDIFQNLVWRASYGRGFRPPSFQELYLRFENPAVGY
VVEGNPNLKPERSITINSDLEYSPFSFLTLSLSLYRNDIINLIQYKFDSNKGKEFAEFQLQNIAKAYTRGGEFGVQYRFL
KYFTLELGYNHTDTRDLNTDRPLEGRALHQASANFIYNSPGGFQFNLRGKHLDKRPFYSATNNLAGQDSIPTEVKLNENP
PVIYGKPFSILNVRIEQKFFNKHFSLFLGVDNVLNQYELTYNPTRPRFYYGGFSAQF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=601, Percent_Identity=25.4575707154742, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790405, Length=149, Percent_Identity=32.8859060402685, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79330; Mature: 79330

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFSILRFKSIQILFPIFFCISIQAQDESTKIGNKVVEKESPNKIITKNNNTTTESLRKE
CCEEEEHHHHHHHHEEEEEEEEEEECCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
NGQNIPEESQIVVTGSRGERRLKDSTVATEVISRKKIEASGARNAAEVLETQLGIDVVPF
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEC
FGGSRVRMLGLDSQYVLILIDGERIAGRLNNAVDLSRFKVQNLERIEIVKGASSALYGAD
CCCCEEEEEECCCCEEEEEECCCHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCHHCCHH
AIGGVINLITREADKKLSYEMRTTYGNGSRKNFNTEGEFNTNANMGFRNEFVSGSVSSGY
HHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
NKNPGYRLVPNSQATTGNAYQDLNTGINLTFNPDGNFKGKTRILYQHRNQNGVDVTQSKA
CCCCCEEECCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCEECCCC
IFDRNNKTHDFLATGSLEYGFGKRNLISFRGNISKWENKYYNNQRGSDELDVKQLNAELT
EECCCCCCCEEEEECCEEECCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCHHHHCHHHC
SQGTVQLDMEASERHFITIGAESFANELESDRLQSRYVYRTRKAVFFQDEWTISSSPRIR
CCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEEEEEEECCEEECCCCCEE
MIPGVRYDDDSQFGNQTTPKLAVRYDIFQNLVWRASYGRGFRPPSFQELYLRFENPAVGY
ECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCHHHEEEEECCCEEEE
VVEGNPNLKPERSITINSDLEYSPFSFLTLSLSLYRNDIINLIQYKFDSNKGKEFAEFQL
EECCCCCCCCCCEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHEEECCCCCCHHHHHHH
QNIAKAYTRGGEFGVQYRFLKYFTLELGYNHTDTRDLNTDRPLEGRALHQASANFIYNSP
HHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCEEEECC
GGFQFNLRGKHLDKRPFYSATNNLAGQDSIPTEVKLNENPPVIYGKPFSILNVRIEQKFF
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCEEEEEEEHHHHH
NKHFSLFLGVDNVLNQYELTYNPTRPRFYYGGFSAQF
CCCEEEEEEHHHHHCCEEEEECCCCCEEEECCCCCCC
>Mature Secondary Structure
MFFSILRFKSIQILFPIFFCISIQAQDESTKIGNKVVEKESPNKIITKNNNTTTESLRKE
CCEEEEHHHHHHHHEEEEEEEEEEECCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
NGQNIPEESQIVVTGSRGERRLKDSTVATEVISRKKIEASGARNAAEVLETQLGIDVVPF
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEC
FGGSRVRMLGLDSQYVLILIDGERIAGRLNNAVDLSRFKVQNLERIEIVKGASSALYGAD
CCCCEEEEEECCCCEEEEEECCCHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCHHCCHH
AIGGVINLITREADKKLSYEMRTTYGNGSRKNFNTEGEFNTNANMGFRNEFVSGSVSSGY
HHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
NKNPGYRLVPNSQATTGNAYQDLNTGINLTFNPDGNFKGKTRILYQHRNQNGVDVTQSKA
CCCCCEEECCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCEECCCC
IFDRNNKTHDFLATGSLEYGFGKRNLISFRGNISKWENKYYNNQRGSDELDVKQLNAELT
EECCCCCCCEEEEECCEEECCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCHHHHCHHHC
SQGTVQLDMEASERHFITIGAESFANELESDRLQSRYVYRTRKAVFFQDEWTISSSPRIR
CCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEEEEEEECCEEECCCCCEE
MIPGVRYDDDSQFGNQTTPKLAVRYDIFQNLVWRASYGRGFRPPSFQELYLRFENPAVGY
ECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCHHHEEEEECCCEEEE
VVEGNPNLKPERSITINSDLEYSPFSFLTLSLSLYRNDIINLIQYKFDSNKGKEFAEFQL
EECCCCCCCCCCEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHEEECCCCCCHHHHHHH
QNIAKAYTRGGEFGVQYRFLKYFTLELGYNHTDTRDLNTDRPLEGRALHQASANFIYNSP
HHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCEEEECC
GGFQFNLRGKHLDKRPFYSATNNLAGQDSIPTEVKLNENPPVIYGKPFSILNVRIEQKFF
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCEEEEEEEHHHHH
NKHFSLFLGVDNVLNQYELTYNPTRPRFYYGGFSAQF
CCCEEEEEEHHHHHCCEEEEECCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]