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The map label for this gene is hemY [H]

Identifier: 116332463

GI number: 116332463

Start: 18800

End: 20101

Strand: Direct

Name: hemY [H]

Synonym: LBJ_4017

Alternate gene names: 116332463

Gene position: 18800-20101 (Clockwise)

Preceding gene: 116332462

Following gene: 116332466

Centisome position: 6.27

GC content: 44.39

Gene sequence:

>1302_bases
GTGAATACGCAACCGCCGGACCATATTGTCGTCGGAACGGGTTTTACAGGGCTTCTTTATGCTACCCTTGCCGTCTTAAA
GGGAGAGTCTGTTCTTCTTTATGAAAAACGGGACCGTTCCGGGGGATTGATCGGGTCCGTTCCGACTCCTTTCGGGCTCG
TGGAGACTGCGGCAAACGGAATCTTAAATTCCTATCAGCTTGAAGAACTCGCTTCCGCACTCAACTTGGATATTCTATCC
ACAAGAAAAAACTCGAAAAAAAGATTTATCTGGAAGGACGGAATTCCAAAAAGAATCCCATTGTCCTTTTTAGAGCTCTT
ACGCCTATTATACGGAGTTTTGACGATACCTGCCGGGATTCGACGGGAAGAATCCGTTTATCAATGGGGAGTTCGTGTTC
TGGGAAAAGGGAGCGTGGAAAGTTTACTGGAACCGGGCTTTGCAGGAGTATATGCAGGAAATTTAAAAGACATGTCGGCC
GAGCTTGTGTTGGGGAGATGGATTTCTTCGGAGGAATCTCTGTTGAAAAATATTCGAGCGGCGATTCAAAAGAAAAAAAC
GGAACAGAAAATACCGAAACAAAGAAGAGGGACCGTAAGTTTTCGAGGCGGCTTGGGGGAATTCCTAAACGTGATGGAAG
CGAAAATCACATCGTCTCCGAATTCCAGGATATTATACTCGGAAGAATCCCCCACCTTAAACTCGCTTAGAAAAAAATAT
CCGAAGGCAAAAATCGTCCTCGCCTGCGGTTTAGAATCTTCTTTAAGATTATTATCCTCTAGTTTTCCCGTTTTCAAAAG
ATACGAAAAAATTTGTAAAACTCTTGGAATTGTGACGGTCACTCGATTCGGCAATCAGCCGTTACTTGGTAAAAAAACTG
GATTTGGAATTCTTTTTCCTCCGGATTCAGGCATACGGGCCCTGGGAGTTTTGCTGAATTCCTCCATCTTTCCGGGAAGG
GTTTCCAAAGGGCATTATTCCGAGACATTTATTTTCGGAGGGGCCTTAGACGTAGACGTTGTGAGACTCAAAGAAAACGA
AATCGTATCCATCTTGGAGGAGGATCGGAAAAAGATTGCAGTCCGAAACGACGAGCCTATCAATCACTACGTTACGATCT
GGAAATCCGCACTTCCCGTATACGACGCCGCACTTCTTGAATTCAACAAAGAGCTGGATCGCGGTTTGCCGCAGGGGATT
TTTGTGGAAGGAAATTTTCGATACGGGATCGGTCTAAGTTCGATTTTAGAAAGGATTTGGAATATTATGCGAAATGGAAA
GGAATTTTCGCTTAGAAATTGA

Upstream 100 bases:

>100_bases
TTTCGATTACAATCCAATGGCGAATTCAGGAATCTCTACTTCCGCGGCGACTCTTGAGTCCAAATACACGTTTGGATACC
GGTATCAATTCTAGAAGCCG

Downstream 100 bases:

>100_bases
TCGGACATTCTCCCGATTTTAGATTCGGAAAGTGTCCTCCTAACTTTTTACAGATACATTCGTTCTTTGAGGATTGAATG
GATTCCAATCCGATTTTTGC

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MNTQPPDHIVVGTGFTGLLYATLAVLKGESVLLYEKRDRSGGLIGSVPTPFGLVETAANGILNSYQLEELASALNLDILS
TRKNSKKRFIWKDGIPKRIPLSFLELLRLLYGVLTIPAGIRREESVYQWGVRVLGKGSVESLLEPGFAGVYAGNLKDMSA
ELVLGRWISSEESLLKNIRAAIQKKKTEQKIPKQRRGTVSFRGGLGEFLNVMEAKITSSPNSRILYSEESPTLNSLRKKY
PKAKIVLACGLESSLRLLSSSFPVFKRYEKICKTLGIVTVTRFGNQPLLGKKTGFGILFPPDSGIRALGVLLNSSIFPGR
VSKGHYSETFIFGGALDVDVVRLKENEIVSILEEDRKKIAVRNDEPINHYVTIWKSALPVYDAALLEFNKELDRGLPQGI
FVEGNFRYGIGLSSILERIWNIMRNGKEFSLRN

Sequences:

>Translated_433_residues
MNTQPPDHIVVGTGFTGLLYATLAVLKGESVLLYEKRDRSGGLIGSVPTPFGLVETAANGILNSYQLEELASALNLDILS
TRKNSKKRFIWKDGIPKRIPLSFLELLRLLYGVLTIPAGIRREESVYQWGVRVLGKGSVESLLEPGFAGVYAGNLKDMSA
ELVLGRWISSEESLLKNIRAAIQKKKTEQKIPKQRRGTVSFRGGLGEFLNVMEAKITSSPNSRILYSEESPTLNSLRKKY
PKAKIVLACGLESSLRLLSSSFPVFKRYEKICKTLGIVTVTRFGNQPLLGKKTGFGILFPPDSGIRALGVLLNSSIFPGR
VSKGHYSETFIFGGALDVDVVRLKENEIVSILEEDRKKIAVRNDEPINHYVTIWKSALPVYDAALLEFNKELDRGLPQGI
FVEGNFRYGIGLSSILERIWNIMRNGKEFSLRN
>Mature_433_residues
MNTQPPDHIVVGTGFTGLLYATLAVLKGESVLLYEKRDRSGGLIGSVPTPFGLVETAANGILNSYQLEELASALNLDILS
TRKNSKKRFIWKDGIPKRIPLSFLELLRLLYGVLTIPAGIRREESVYQWGVRVLGKGSVESLLEPGFAGVYAGNLKDMSA
ELVLGRWISSEESLLKNIRAAIQKKKTEQKIPKQRRGTVSFRGGLGEFLNVMEAKITSSPNSRILYSEESPTLNSLRKKY
PKAKIVLACGLESSLRLLSSSFPVFKRYEKICKTLGIVTVTRFGNQPLLGKKTGFGILFPPDSGIRALGVLLNSSIFPGR
VSKGHYSETFIFGGALDVDVVRLKENEIVSILEEDRKKIAVRNDEPINHYVTIWKSALPVYDAALLEFNKELDRGLPQGI
FVEGNFRYGIGLSSILERIWNIMRNGKEFSLRN

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. May have an essential extracellular function during development, possibly as a pheromone [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR016040
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 48094; Mature: 48094

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQPPDHIVVGTGFTGLLYATLAVLKGESVLLYEKRDRSGGLIGSVPTPFGLVETAANG
CCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHH
ILNSYQLEELASALNLDILSTRKNSKKRFIWKDGIPKRIPLSFLELLRLLYGVLTIPAGI
HHHHHHHHHHHHHHCCHHEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
RREESVYQWGVRVLGKGSVESLLEPGFAGVYAGNLKDMSAELVLGRWISSEESLLKNIRA
CCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHH
AIQKKKTEQKIPKQRRGTVSFRGGLGEFLNVMEAKITSSPNSRILYSEESPTLNSLRKKY
HHHHHHHHHHCCHHHCCCEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHC
PKAKIVLACGLESSLRLLSSSFPVFKRYEKICKTLGIVTVTRFGNQPLLGKKTGFGILFP
CCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEEC
PDSGIRALGVLLNSSIFPGRVSKGHYSETFIFGGALDVDVVRLKENEIVSILEEDRKKIA
CCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHEE
VRNDEPINHYVTIWKSALPVYDAALLEFNKELDRGLPQGIFVEGNFRYGIGLSSILERIW
ECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCHHHHHHHHH
NIMRNGKEFSLRN
HHHHCCCCCCCCC
>Mature Secondary Structure
MNTQPPDHIVVGTGFTGLLYATLAVLKGESVLLYEKRDRSGGLIGSVPTPFGLVETAANG
CCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHH
ILNSYQLEELASALNLDILSTRKNSKKRFIWKDGIPKRIPLSFLELLRLLYGVLTIPAGI
HHHHHHHHHHHHHHCCHHEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
RREESVYQWGVRVLGKGSVESLLEPGFAGVYAGNLKDMSAELVLGRWISSEESLLKNIRA
CCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHH
AIQKKKTEQKIPKQRRGTVSFRGGLGEFLNVMEAKITSSPNSRILYSEESPTLNSLRKKY
HHHHHHHHHHCCHHHCCCEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHC
PKAKIVLACGLESSLRLLSSSFPVFKRYEKICKTLGIVTVTRFGNQPLLGKKTGFGILFP
CCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEEC
PDSGIRALGVLLNSSIFPGRVSKGHYSETFIFGGALDVDVVRLKENEIVSILEEDRKKIA
CCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHEE
VRNDEPINHYVTIWKSALPVYDAALLEFNKELDRGLPQGIFVEGNFRYGIGLSSILERIW
ECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCHHHHHHHHH
NIMRNGKEFSLRN
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1372277; 8621504 [H]