Click here to switch to the map view.

The map label for this gene is aer [H]

Identifier: 116329516

GI number: 116329516

Start: 3560847

End: 3562544

Strand: Direct

Name: aer [H]

Synonym: LBL_2991

Alternate gene names: 116329516

Gene position: 3560847-3562544 (Clockwise)

Preceding gene: 116329508

Following gene: 116329517

Centisome position: 98.52

GC content: 39.1

Gene sequence:

>1698_bases
ATGAGAAAAAATCTTCCGATTACAAATCAAAAGATAGAAATACCTGCCAATGCGGTTCTAATTTCATGTACGGATACTAA
AGGAAGAATTTCGTATGTAAGTCAGGACTTTGCGCATATTAGCGGTTTTTCCGAGAGGGAAATGGTGGGTGAATCTCACA
ATCTTATCCGCCATCCGGCCGTTCCTCCTGAGGTCTTTCGAGAAATGTGGGAAACAATCAAAGGAGGAAATCCTTGGAGT
GGAGTTATAAAAAACCGAGCGAAGTCGGGAGATTATTATTGGGTGGATGCCACCATTACTCCAGTGATGAGTGAAGGTGT
CGTATCCGGTTATATGTCTGTCCGGAAAAAAGCGACTCAGCAACAAATCAAAAGGGCGGAAATTCTTTTCGACGATTTGC
GGGATACGAAGTCGTTTTTCTGGAAACTAAAAGCAGGCATTCGAACGTTACTCAAAAAATTAGGAATTTCCGGAAGGATT
TTCTTATATGTTTCATTCGCTTTTGTCCCTTTGTTGTCAGCGAATTTCGAGTGGATCCGAAACGGTTTGTTTTTTTTACC
CGTCTTTGGTATTGTTTGTGGGACGATCGGAGTATTTCTTTTGGTAAAAACGATTCTGAATTATCGAAAAGAAATCCGAG
AAGTCATTTCAATTCAAAAAGAGATCGTATCCGGAAACTTTCTCATAGAAGTTCCCGAAAAAAAAGGAAGTTCCGAAATA
TTTGAAATTTATTCCGGCCTTCATATACTTATAATCAGCATTTGGGGATTGTTGGTTCAGATTAAAGAGAATTTCGAAAA
GAACCAAGAACTTTATCGATATCTTTCCCAATCGACCGAACAATTTCAATTAAAAACCCATAACCAGGCGGCCTCCGTGG
AAGAGACTGCATCTGCGTCGCAGGAATTGTCCTCAACTTTGGATGGGATTGTAAAATCGATTCATTTACAATTGTCTAGT
TTGACGGCAATCAACGATGGAATTGGAAAAGTAAACGAATCAATTCGAAACGTGTCTAAGTCGATGGATAGCCTTGCTTC
TCAGACCACTTCCGTAAAACAAAAGGCTTTTCAAAGCGAGGAAACATTCGAAGGGGCGATTCTCGCAATGAATGAAATTA
AAGAATATTCTAATGGAATTTCAAAGATCGTCGAAATTATCACTTCGATTTCAGAAAAAACGAATTTGTTGTCATTGAAC
GCATCCATAGAATCTGCAAGAGCGGGTGAAGCGGGAAAAGGTTTTAGCGTGGTGGCGGAAGAGATATCAAAATTAGCGGA
TCAGACTCGAAAATCGATTAAGGATATTATCAATCTAATCGACAATACTACGAAAGCAGTTGATCTTGGGGCGGAAAAAT
TTCAAAAATCTTTAACTATCATCAAACAACTTACGGATTATATCGGTGAAGTGAATTCTTCCGCAACGATCGTAACAGCG
TCTCTGTTTGCTCAAGTGGAGAAATTAGCTGAAATCAGAAAAAGTACGGATCAAGTCAATCGACTCGGTGAAACTGTGAG
TGAAACTTCCGGGTTTCAAAAAACCGCTTCCGAGGAAATTTCTTTATCGATGCAGAATATTGCGGAAAATTCCGAATCCA
TTGCTAGAACTTCAGAAGAGATAAAACAACTTGTGGACGAATCGATTCTCAAAGCCACGAAATTGTATGAAATTCTAAAA
CATTTTAAAACGTCTTAG

Upstream 100 bases:

>100_bases
TCCGGTTAACTTTCTATGTTCATTTCTTTTCCGTAGTTATTTGAAATTTTCCTTTTAACTACTTGGTATTTATTTTTTAT
GTAACGAATAAGGATTTTGA

Downstream 100 bases:

>100_bases
AGTTTATCCCAAAATCTCAAATAATATCTCTAAACTTTCAGCAAGTTTCTGGAAAAATGTAGTAGTTCCTACACTTTGAG
ATGGGTTTTAATTTTCTCGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MRKNLPITNQKIEIPANAVLISCTDTKGRISYVSQDFAHISGFSEREMVGESHNLIRHPAVPPEVFREMWETIKGGNPWS
GVIKNRAKSGDYYWVDATITPVMSEGVVSGYMSVRKKATQQQIKRAEILFDDLRDTKSFFWKLKAGIRTLLKKLGISGRI
FLYVSFAFVPLLSANFEWIRNGLFFLPVFGIVCGTIGVFLLVKTILNYRKEIREVISIQKEIVSGNFLIEVPEKKGSSEI
FEIYSGLHILIISIWGLLVQIKENFEKNQELYRYLSQSTEQFQLKTHNQAASVEETASASQELSSTLDGIVKSIHLQLSS
LTAINDGIGKVNESIRNVSKSMDSLASQTTSVKQKAFQSEETFEGAILAMNEIKEYSNGISKIVEIITSISEKTNLLSLN
ASIESARAGEAGKGFSVVAEEISKLADQTRKSIKDIINLIDNTTKAVDLGAEKFQKSLTIIKQLTDYIGEVNSSATIVTA
SLFAQVEKLAEIRKSTDQVNRLGETVSETSGFQKTASEEISLSMQNIAENSESIARTSEEIKQLVDESILKATKLYEILK
HFKTS

Sequences:

>Translated_565_residues
MRKNLPITNQKIEIPANAVLISCTDTKGRISYVSQDFAHISGFSEREMVGESHNLIRHPAVPPEVFREMWETIKGGNPWS
GVIKNRAKSGDYYWVDATITPVMSEGVVSGYMSVRKKATQQQIKRAEILFDDLRDTKSFFWKLKAGIRTLLKKLGISGRI
FLYVSFAFVPLLSANFEWIRNGLFFLPVFGIVCGTIGVFLLVKTILNYRKEIREVISIQKEIVSGNFLIEVPEKKGSSEI
FEIYSGLHILIISIWGLLVQIKENFEKNQELYRYLSQSTEQFQLKTHNQAASVEETASASQELSSTLDGIVKSIHLQLSS
LTAINDGIGKVNESIRNVSKSMDSLASQTTSVKQKAFQSEETFEGAILAMNEIKEYSNGISKIVEIITSISEKTNLLSLN
ASIESARAGEAGKGFSVVAEEISKLADQTRKSIKDIINLIDNTTKAVDLGAEKFQKSLTIIKQLTDYIGEVNSSATIVTA
SLFAQVEKLAEIRKSTDQVNRLGETVSETSGFQKTASEEISLSMQNIAENSESIARTSEEIKQLVDESILKATKLYEILK
HFKTS
>Mature_565_residues
MRKNLPITNQKIEIPANAVLISCTDTKGRISYVSQDFAHISGFSEREMVGESHNLIRHPAVPPEVFREMWETIKGGNPWS
GVIKNRAKSGDYYWVDATITPVMSEGVVSGYMSVRKKATQQQIKRAEILFDDLRDTKSFFWKLKAGIRTLLKKLGISGRI
FLYVSFAFVPLLSANFEWIRNGLFFLPVFGIVCGTIGVFLLVKTILNYRKEIREVISIQKEIVSGNFLIEVPEKKGSSEI
FEIYSGLHILIISIWGLLVQIKENFEKNQELYRYLSQSTEQFQLKTHNQAASVEETASASQELSSTLDGIVKSIHLQLSS
LTAINDGIGKVNESIRNVSKSMDSLASQTTSVKQKAFQSEETFEGAILAMNEIKEYSNGISKIVEIITSISEKTNLLSLN
ASIESARAGEAGKGFSVVAEEISKLADQTRKSIKDIINLIDNTTKAVDLGAEKFQKSLTIIKQLTDYIGEVNSSATIVTA
SLFAQVEKLAEIRKSTDQVNRLGETVSETSGFQKTASEEISLSMQNIAENSESIARTSEEIKQLVDESILKATKLYEILK
HFKTS

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=509, Percent_Identity=26.9155206286837, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1787690, Length=295, Percent_Identity=26.4406779661017, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788195, Length=272, Percent_Identity=26.1029411764706, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367378, Length=202, Percent_Identity=29.2079207920792, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788194, Length=279, Percent_Identity=24.3727598566308, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 62918; Mature: 62918

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLPITNQKIEIPANAVLISCTDTKGRISYVSQDFAHISGFSEREMVGESHNLIRHPA
CCCCCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
VPPEVFREMWETIKGGNPWSGVIKNRAKSGDYYWVDATITPVMSEGVVSGYMSVRKKATQ
CCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
QQIKRAEILFDDLRDTKSFFWKLKAGIRTLLKKLGISGRIFLYVSFAFVPLLSANFEWIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCHHHHH
NGLFFLPVFGIVCGTIGVFLLVKTILNYRKEIREVISIQKEIVSGNFLIEVPEKKGSSEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHH
FEIYSGLHILIISIWGLLVQIKENFEKNQELYRYLSQSTEQFQLKTHNQAASVEETASAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHH
QELSSTLDGIVKSIHLQLSSLTAINDGIGKVNESIRNVSKSMDSLASQTTSVKQKAFQSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ETFEGAILAMNEIKEYSNGISKIVEIITSISEKTNLLSLNASIESARAGEAGKGFSVVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHCCCCCCCCHHHHHH
EISKLADQTRKSIKDIINLIDNTTKAVDLGAEKFQKSLTIIKQLTDYIGEVNSSATIVTA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLFAQVEKLAEIRKSTDQVNRLGETVSETSGFQKTASEEISLSMQNIAENSESIARTSEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IKQLVDESILKATKLYEILKHFKTS
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKNLPITNQKIEIPANAVLISCTDTKGRISYVSQDFAHISGFSEREMVGESHNLIRHPA
CCCCCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
VPPEVFREMWETIKGGNPWSGVIKNRAKSGDYYWVDATITPVMSEGVVSGYMSVRKKATQ
CCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
QQIKRAEILFDDLRDTKSFFWKLKAGIRTLLKKLGISGRIFLYVSFAFVPLLSANFEWIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCHHHHH
NGLFFLPVFGIVCGTIGVFLLVKTILNYRKEIREVISIQKEIVSGNFLIEVPEKKGSSEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHH
FEIYSGLHILIISIWGLLVQIKENFEKNQELYRYLSQSTEQFQLKTHNQAASVEETASAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHH
QELSSTLDGIVKSIHLQLSSLTAINDGIGKVNESIRNVSKSMDSLASQTTSVKQKAFQSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ETFEGAILAMNEIKEYSNGISKIVEIITSISEKTNLLSLNASIESARAGEAGKGFSVVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHCCCCCCCCHHHHHH
EISKLADQTRKSIKDIINLIDNTTKAVDLGAEKFQKSLTIIKQLTDYIGEVNSSATIVTA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLFAQVEKLAEIRKSTDQVNRLGETVSETSGFQKTASEEISLSMQNIAENSESIARTSEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IKQLVDESILKATKLYEILKHFKTS
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]