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The map label for this gene is murA [H]

Identifier: 116329412

GI number: 116329412

Start: 3430371

End: 3431669

Strand: Direct

Name: murA [H]

Synonym: LBL_2877

Alternate gene names: 116329412

Gene position: 3430371-3431669 (Clockwise)

Preceding gene: 116329410

Following gene: 116329413

Centisome position: 94.91

GC content: 45.65

Gene sequence:

>1299_bases
ATGAGATCTTCGTATTTCAAGATCATTGGAAAAACCCCTCTTCATGGAACAGTGGTTCCACAGGGAAATAAAAATGAAGC
TTTGCCATTACTCGGTGCAGTTTGTATGGTTCCGGGAACCGTTCGTATTAGCAACATCCCGGTTATCTCAGACGTACTCA
TGCTCATGGAAGTTCTCCGCCACTTAGGTATGGAAATCACTGAAGAAGAACCTGGAACTTACACTTTCAAACACGACGGT
AATCTAAAGAATCAACTTCCCGAAGAGCTTTGTTCTCGCATTCGTGGCGCCGTCACTTTAGCGGGTCCGATTCTTGCGAT
TACGGGAAGAGTTTTCTTACCGAAGCCTGGAGGAGATAAAATAGGAAGAAGAAGATTAGATACTCATCTTCTCGCGTTAC
AAGCATTAGGCGCCAATATAGAAGTTTTTCCGGACGGTTACGAAATTAAGGCAGACCAATTGAGAGGAACGGATATTCTA
ATGGACGAGGCTTCCGTAACCGGAACGGAAAATGCAGTAATGGCTGCAGTCCTTGCGGAAGGAGTCACGATTCTTCGACA
TGCGGCGAGTGAACCTCATGTACAAAGACTTTGTCATTTTTTAAACTCCGCGGGAGCAAAAATTTCTGGAATCGGTTCAA
ACATCCTTACAATCGAAGGAGTAACCTCTTTAAAACCTCCCGCAAAAGAACACAAAATCGGATCGGACTATCTCGAAGTC
GGCTCGTTTATCAGCTTGGCCGCTGTCACGGGCGGAGAACTGATGATTCGAGATGTAGAACTGGAAGACATTCGTATGAT
TCGAATGGTTTATTCCCGGCTTGGAATAGAGGTACGCCCACATGAAAACGGAATCCTAGTTCCTTCCGACCAAAAGATGG
AAATCACTCCGGATTATCACGGAGCTACTCCTAAGATAGACGATTCTCCCTGGCCAGGTTTCCCCGCGGATATGACCTCG
GTTGCTCTTGTAACCGCAACTCAGTGTAAAGGAACAGTTTTGATCCACGAGAAAATGTTCGAATCCAGACTTTTCTTCGT
GGATAATATCATCGCAATGGGAGCCCAGATCATTCTTTGCGATCCTCATAGAGCTATTGTTATCGGACATTCCAGATTGT
ATGGACAAAAGGTGGCCAGTCCGGACATACGCGCCGGGATGGCGATGATTATTGCCGCTCTTTGTGCGGAAGGGACGAGT
ACTATCCATAATATAGGTCAGGTCGATCGAGGTTTTGAAAATATTGATACTCGTCTGCGTGCGTTAGGTGCAAGAATCGA
AAGAGTAAACGCAGATTGA

Upstream 100 bases:

>100_bases
TCCAAAGATCGATCCGAGTAAAATTCAAAGCAAACGAATCAAAAGTCGCTTTCGATTACAATTCGATTGCCAGAAAGACC
GTATCCTACAGCTTATCATT

Downstream 100 bases:

>100_bases
ACCGAAAAGATTTTTTTAAAAAAGGTTTTGCGAAGATATTCGACTTCGCTCGGGAAAATGCGGCGGATCTAGTTTCCGGT
TTTCAAGAAATCGTTTCCGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLRHLGMEITEEEPGTYTFKHDG
NLKNQLPEELCSRIRGAVTLAGPILAITGRVFLPKPGGDKIGRRRLDTHLLALQALGANIEVFPDGYEIKADQLRGTDIL
MDEASVTGTENAVMAAVLAEGVTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEITPDYHGATPKIDDSPWPGFPADMTS
VALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILCDPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTS
TIHNIGQVDRGFENIDTRLRALGARIERVNAD

Sequences:

>Translated_432_residues
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLRHLGMEITEEEPGTYTFKHDG
NLKNQLPEELCSRIRGAVTLAGPILAITGRVFLPKPGGDKIGRRRLDTHLLALQALGANIEVFPDGYEIKADQLRGTDIL
MDEASVTGTENAVMAAVLAEGVTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEITPDYHGATPKIDDSPWPGFPADMTS
VALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILCDPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTS
TIHNIGQVDRGFENIDTRLRALGARIERVNAD
>Mature_432_residues
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLRHLGMEITEEEPGTYTFKHDG
NLKNQLPEELCSRIRGAVTLAGPILAITGRVFLPKPGGDKIGRRRLDTHLLALQALGANIEVFPDGYEIKADQLRGTDIL
MDEASVTGTENAVMAAVLAEGVTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEITPDYHGATPKIDDSPWPGFPADMTS
VALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILCDPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTS
TIHNIGQVDRGFENIDTRLRALGARIERVNAD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=433, Percent_Identity=33.9491916859122, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46811; Mature: 46811

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLR
CCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHH
HLGMEITEEEPGTYTFKHDGNLKNQLPEELCSRIRGAVTLAGPILAITGRVFLPKPGGDK
HCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEECCCEEEEECEEEEECCCCCH
IGRRRLDTHLLALQALGANIEVFPDGYEIKADQLRGTDILMDEASVTGTENAVMAAVLAE
HHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHH
GVTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
HHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCCCHHHCCCCCHHHHH
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEITPDYH
HHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCEECCCCCCEEECCCCC
GATPKIDDSPWPGFPADMTSVALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILC
CCCCCCCCCCCCCCCCCHHHEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEE
DPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTSTIHNIGQVDRGFENIDTRLR
CCCCEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
ALGARIERVNAD
HHHHHHHHCCCC
>Mature Secondary Structure
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLR
CCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHH
HLGMEITEEEPGTYTFKHDGNLKNQLPEELCSRIRGAVTLAGPILAITGRVFLPKPGGDK
HCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEECCCEEEEECEEEEECCCCCH
IGRRRLDTHLLALQALGANIEVFPDGYEIKADQLRGTDILMDEASVTGTENAVMAAVLAE
HHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHH
GVTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
HHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCCCHHHCCCCCHHHHH
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEITPDYH
HHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCEECCCCCCEEECCCCC
GATPKIDDSPWPGFPADMTSVALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILC
CCCCCCCCCCCCCCCCCHHHEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEE
DPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTSTIHNIGQVDRGFENIDTRLR
CCCCEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
ALGARIERVNAD
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA