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The map label for this gene is gpsA [H]

Identifier: 116329243

GI number: 116329243

Start: 3175958

End: 3176965

Strand: Direct

Name: gpsA [H]

Synonym: LBL_2682

Alternate gene names: 116329243

Gene position: 3175958-3176965 (Clockwise)

Preceding gene: 116329234

Following gene: 116329244

Centisome position: 87.87

GC content: 44.05

Gene sequence:

>1008_bases
ATGAAAATCGGAGTGATCGGGTCGGGAAGTTTCGGAACCGCTTTGGGAAGTCTTCTTGCGGATAAAGGTTACGAAGTCAC
CCTCTGGTGTAGGAACGACTCTCAAATCGAAAGTATCAATCGTAATCATATCAATAATAAACATCTTCCCGATTTTACGC
TTCCGGAAAAGCTAACTGCAAGCAAGGATTTAAGAACCGTCGTTCAAGGGAAGGACATGATCGTATCTTCCCCACCTTCT
CATGCGTTGACCGAAATTTTAAGAGAGATTAAAGAATACCTTCCTGAAAAAGTTCCTATCGTATCCGCGAGTAAAGGAAT
TGAAAACGGGACACTTCGTCTTGTATCCGAAATTTTCGAATCGGAACTCCCCGGAAAATATCACTCGTATCTTTCGTATT
TGTCCGGACCTTCTTTTGCAAAAGAGATCATTCAAAAAGTACCCACGATCGTGAGCATTGCTTCTAGGAGCGAAACGACC
GCTCGTAAGGTTCAGGAAATATTCAGTTTTTTATATTTTCGAACCTATTGGACTCCGGATGTGATCGGTGTGGAAGTGGG
AGGTTCTTTGAAGAACGTGATCGCATTGGCGGCAGGAGTCAGCGACGGCCTTGGCTTCGGTCAAAACACAAGAGCGGCTT
TAATCACAAGAGGATTGAACGAGATCACGAAAATCGGTTTGAAGCTGGGCGCCGATCCGATGACTTTTCTCGGACCTTCC
GGAATGGGGGATTTGATTTTGACTTGTTGCGGAGGACAATCTCGAAATCGTACGGTCGGTTTTCGTTTGGGAAAGGGAGA
AACCTTGGAGCAAATTCTCTCCGGTATGAACGAGGTCGCGGAAGGAATAAAGACTACTCAAAGCGCATATGAACTTTCAC
AAAAGTTGGGGATTGAAATGGCGATTACGAACGAAGTTTATAAAATGCTTTACGAAGACAAGAATCCGAAAGAAGTTGTG
AAAGACCTTATGAAACGCGATCTAAAGAGAGAAGGCGTTTTAGTTTGA

Upstream 100 bases:

>100_bases
GGGTAAAGAAGAGTAAACTAAATTATTGAGTCGGGAACGGTTGTTTCGAAATCGTTTGGTGTAAAATTTTTTTGACTTCA
ACCTCACAATAGGAGCCTTC

Downstream 100 bases:

>100_bases
TCGACATTGAAGCTTCTTTCCTTTAAATTCCGTTTTTGTTTACTCTTAAGTCTTGTATATTCTCATTCGATTGTCGCTCA
AACAAAGCAGGAATTCGGAT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQIESINRNHINNKHLPDFTLPEKLTASKDLRTVVQGKDMIVSSPPS
HALTEILREIKEYLPEKVPIVSASKGIENGTLRLVSEIFESELPGKYHSYLSYLSGPSFAKEIIQKVPTIVSIASRSETT
ARKVQEIFSFLYFRTYWTPDVIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
GMGDLILTCCGGQSRNRTVGFRLGKGETLEQILSGMNEVAEGIKTTQSAYELSQKLGIEMAITNEVYKMLYEDKNPKEVV
KDLMKRDLKREGVLV

Sequences:

>Translated_335_residues
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQIESINRNHINNKHLPDFTLPEKLTASKDLRTVVQGKDMIVSSPPS
HALTEILREIKEYLPEKVPIVSASKGIENGTLRLVSEIFESELPGKYHSYLSYLSGPSFAKEIIQKVPTIVSIASRSETT
ARKVQEIFSFLYFRTYWTPDVIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
GMGDLILTCCGGQSRNRTVGFRLGKGETLEQILSGMNEVAEGIKTTQSAYELSQKLGIEMAITNEVYKMLYEDKNPKEVV
KDLMKRDLKREGVLV
>Mature_335_residues
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQIESINRNHINNKHLPDFTLPEKLTASKDLRTVVQGKDMIVSSPPS
HALTEILREIKEYLPEKVPIVSASKGIENGTLRLVSEIFESELPGKYHSYLSYLSGPSFAKEIIQKVPTIVSIASRSETT
ARKVQEIFSFLYFRTYWTPDVIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
GMGDLILTCCGGQSRNRTVGFRLGKGETLEQILSGMNEVAEGIKTTQSAYELSQKLGIEMAITNEVYKMLYEDKNPKEVV
KDLMKRDLKREGVLV

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=349, Percent_Identity=30.3724928366762, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI24307999, Length=345, Percent_Identity=29.5652173913043, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=42.9878048780488, Blast_Score=276, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17507425, Length=320, Percent_Identity=30.3125, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32564399, Length=346, Percent_Identity=30.0578034682081, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI193210136, Length=355, Percent_Identity=29.5774647887324, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32564403, Length=355, Percent_Identity=29.5774647887324, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193210134, Length=343, Percent_Identity=28.2798833819242, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324513, Length=361, Percent_Identity=28.2548476454294, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320181, Length=360, Percent_Identity=29.1666666666667, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI22026922, Length=350, Percent_Identity=28, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17136204, Length=341, Percent_Identity=24.633431085044, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17136200, Length=341, Percent_Identity=24.633431085044, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136202, Length=341, Percent_Identity=24.633431085044, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45551945, Length=299, Percent_Identity=28.4280936454849, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281362270, Length=299, Percent_Identity=28.4280936454849, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648969, Length=252, Percent_Identity=29.7619047619048, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36636; Mature: 36636

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQIESINRNHINNKHLPDFTLPEKLTA
CEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHH
SKDLRTVVQGKDMIVSSPPSHALTEILREIKEYLPEKVPIVSASKGIENGTLRLVSEIFE
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHH
SELPGKYHSYLSYLSGPSFAKEIIQKVPTIVSIASRSETTARKVQEIFSFLYFRTYWTPD
HCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
VIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
GMGDLILTCCGGQSRNRTVGFRLGKGETLEQILSGMNEVAEGIKTTQSAYELSQKLGIEM
CCCHHHEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
AITNEVYKMLYEDKNPKEVVKDLMKRDLKREGVLV
EHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQIESINRNHINNKHLPDFTLPEKLTA
CEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHH
SKDLRTVVQGKDMIVSSPPSHALTEILREIKEYLPEKVPIVSASKGIENGTLRLVSEIFE
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHH
SELPGKYHSYLSYLSGPSFAKEIIQKVPTIVSIASRSETTARKVQEIFSFLYFRTYWTPD
HCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
VIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
GMGDLILTCCGGQSRNRTVGFRLGKGETLEQILSGMNEVAEGIKTTQSAYELSQKLGIEM
CCCHHHEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
AITNEVYKMLYEDKNPKEVVKDLMKRDLKREGVLV
EHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA