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The map label for this gene is pBP3 [H]

Identifier: 116329214

GI number: 116329214

Start: 3141098

End: 3142906

Strand: Direct

Name: pBP3 [H]

Synonym: LBL_2647

Alternate gene names: 116329214

Gene position: 3141098-3142906 (Clockwise)

Preceding gene: 116329206

Following gene: 116329215

Centisome position: 86.9

GC content: 44.44

Gene sequence:

>1809_bases
ATGAAATCCCACAAAACCAGACTTACAATTTTATTTTCTTTTCTCTGTATTCTCTTCTGCATCCTCATCGGGAGGGTCGT
TTTTCTCACATTTTGGAACGAGCGAGAAGTAGTTCTAAAAACCGGAGATCGAATCATGCGAGGTGCGATCTATGACCGAA
GAGGAATCGAACTCGCGATGACCGTCGATTCCGCCACGATCGGAATCTATCCCGCAAACATCTATGATCCGAACTTTACC
GCGGTTCAGTTGGCTCCGTATTTGGACATGCCTCCTGAAAAAATCGAAGCTATGATCCGGGAAAAGAGTCGTTATTTTCT
GTTAAAGAGAGAGATCGACGAATCTCTCGGAAATAAGATTATGGAACTTTCTCTACCCGGAGTACGAAGAGAAAAAGAAT
ACAAACGAGTGTATCCACACGGAAACCTCGCGTCCAGTCTTGTAGGTTTTACGGGAATGGACGACGACCGCGCCCTCTCC
GGTTTGGAAGTCCAATACAATCAGGAACTAATGACTCCGACCGAATCGGATTCTTCGAGAGGAAGTAATCTTCATCTAAC
GATCGACGGCCTGATTCAATACAAACTCGAAAAGGCTCTCGGTAAACGATTCGAAGAAACCGGCTCGAAAAAGGCTATCG
GGATTTTGATGGATATCAATACTGGAAAAATCTTAGCGTCCGCTTCCTTCCCGGCATTCGATCCCAATCAATATAACGAA
TCCGGAGAAGACTCCCATACGAACTGGGCGATACGTCACGTTTACGAACCCGGTTCCACGATGAAAATTTTCCTGGCCTC
TGTTCTATTCAATGAAAATCTAATACGTCCGGACGAAAAATTCCACTGCCCCGGGTACGTGGAACTCGGTAAAACAAAGA
TCAAATGTACGAATGCGCATGGACATCTAAACTTAGAGGAAATTCTACAGTATTCTTGCAACGTGGGAATCATCAAAGCC
TCCCAAAGAATCCCCGAAGCTTTACTTTATGATTACATGAAGAAGTTTCAATTTGGAGAAAAGACGGGATTTTTACCGAA
CGAATCAGCAGGTTATTTTCCTCCTTTGAAAAAATGGACCCCTGCAACTTCCATGTTTATGGCGATCGGACAAGGTATCT
CGGTGACCCCTATTCAATTAGTCGCTTCCGCAGCTTCGGTGGCCAACGGCGGAAGGATGCTGACTCCCCGGGTCGTTTCT
CATTTCAGCGACTCTTACGGAGCAATTCTTCACGAATTTAAAACTCAAGAAACTCCGATCGGAATTCGCGAATACACGAC
GGAAAAGATTCTCAAAGCGATGACAAGAGTTGTTCAATCCGGAACAGGAAAAAACGCCTACATTCAAGAATATTCCATCG
CCGGTAAAACGGGTACGGGCCAAAAAGCTATATCAGGAAAAGGTTATGTAGAGGGATTATGGTCGGCTTCTTTCCTGGGT
TTTTTTCCCGCGGAACGACCCAAAATCGTAGGATTGATTCTTTTTGACGAACCAAAAGGCGGCACACACTCGGGAGGCGG
CCTCGCAGCCCCCGTTTTCAAAGAAGTTGTCGAGAATATCATTCCTATCATAGAACAAGGGGAAAGGACCTTAAATGTTT
CTTTAAAACATTTTCAAAGAAAAAACCTAAAGGGAACTAACGTGGGGGAAATTCCGAATCTCATCGGAAAAAGTAAACGG
GAAGCTCTGGAAATTTTAAGACCCTCGGGAATTCCGGTTAAGTTTCATGGAAGCGGATTTTGTTATAAACAAGAACCTGA
CCCAGGGAAAAAAGCCGAAGACGAAAGACTGAATCTGTATTTCAAGTAA

Upstream 100 bases:

>100_bases
CATAGCAATCGAGGAAGGAAAAATTTCATTCTTATGTCGGCTGTAATTTCGAAACATCACTTTTCGAAATCAAGGTTTCG
GTCGATTCTGTAAAAAGAGA

Downstream 100 bases:

>100_bases
ACGCTATATTCTTAAATGATAATGCAGCCTTCCACGAATGAATCGATCCTTAAAAAAAATCTGAAAAGTTTGTCCGTATT
CAACATTTCTGTCGGAGAAA

Product: penicillin-binding protein 3

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MKSHKTRLTILFSFLCILFCILIGRVVFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAMTVDSATIGIYPANIYDPNFT
AVQLAPYLDMPPEKIEAMIREKSRYFLLKREIDESLGNKIMELSLPGVRREKEYKRVYPHGNLASSLVGFTGMDDDRALS
GLEVQYNQELMTPTESDSSRGSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMDINTGKILASASFPAFDPNQYNE
SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRPDEKFHCPGYVELGKTKIKCTNAHGHLNLEEILQYSCNVGIIKA
SQRIPEALLYDYMKKFQFGEKTGFLPNESAGYFPPLKKWTPATSMFMAIGQGISVTPIQLVASAASVANGGRMLTPRVVS
HFSDSYGAILHEFKTQETPIGIREYTTEKILKAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAISGKGYVEGLWSASFLG
FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKHFQRKNLKGTNVGEIPNLIGKSKR
EALEILRPSGIPVKFHGSGFCYKQEPDPGKKAEDERLNLYFK

Sequences:

>Translated_602_residues
MKSHKTRLTILFSFLCILFCILIGRVVFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAMTVDSATIGIYPANIYDPNFT
AVQLAPYLDMPPEKIEAMIREKSRYFLLKREIDESLGNKIMELSLPGVRREKEYKRVYPHGNLASSLVGFTGMDDDRALS
GLEVQYNQELMTPTESDSSRGSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMDINTGKILASASFPAFDPNQYNE
SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRPDEKFHCPGYVELGKTKIKCTNAHGHLNLEEILQYSCNVGIIKA
SQRIPEALLYDYMKKFQFGEKTGFLPNESAGYFPPLKKWTPATSMFMAIGQGISVTPIQLVASAASVANGGRMLTPRVVS
HFSDSYGAILHEFKTQETPIGIREYTTEKILKAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAISGKGYVEGLWSASFLG
FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKHFQRKNLKGTNVGEIPNLIGKSKR
EALEILRPSGIPVKFHGSGFCYKQEPDPGKKAEDERLNLYFK
>Mature_602_residues
MKSHKTRLTILFSFLCILFCILIGRVVFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAMTVDSATIGIYPANIYDPNFT
AVQLAPYLDMPPEKIEAMIREKSRYFLLKREIDESLGNKIMELSLPGVRREKEYKRVYPHGNLASSLVGFTGMDDDRALS
GLEVQYNQELMTPTESDSSRGSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMDINTGKILASASFPAFDPNQYNE
SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRPDEKFHCPGYVELGKTKIKCTNAHGHLNLEEILQYSCNVGIIKA
SQRIPEALLYDYMKKFQFGEKTGFLPNESAGYFPPLKKWTPATSMFMAIGQGISVTPIQLVASAASVANGGRMLTPRVVS
HFSDSYGAILHEFKTQETPIGIREYTTEKILKAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAISGKGYVEGLWSASFLG
FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKHFQRKNLKGTNVGEIPNLIGKSKR
EALEILRPSGIPVKFHGSGFCYKQEPDPGKKAEDERLNLYFK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=577, Percent_Identity=26.8630849220104, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI1786854, Length=490, Percent_Identity=24.2857142857143, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 67127; Mature: 67127

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHKTRLTILFSFLCILFCILIGRVVFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCHHHHHHHCCCCCCEEEE
TVDSATIGIYPANIYDPNFTAVQLAPYLDMPPEKIEAMIREKSRYFLLKREIDESLGNKI
EECCEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
MELSLPGVRREKEYKRVYPHGNLASSLVGFTGMDDDRALSGLEVQYNQELMTPTESDSSR
EEECCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCEEEECCHHCCCCCCCCCC
GSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMDINTGKILASASFPAFDPNQYNE
CCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCC
SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRPDEKFHCPGYVELGKTKIKCTNAH
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCEEEEEECCC
GHLNLEEILQYSCNVGIIKASQRIPEALLYDYMKKFQFGEKTGFLPNESAGYFPPLKKWT
CCCCHHHHHHHHCCCEEEECCHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PATSMFMAIGQGISVTPIQLVASAASVANGGRMLTPRVVSHFSDSYGAILHEFKTQETPI
CHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHCCHHHHHHHHHHCCCCCC
GIREYTTEKILKAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAISGKGYVEGLWSASFLG
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKHFQR
CCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
KNLKGTNVGEIPNLIGKSKREALEILRPSGIPVKFHGSGFCYKQEPDPGKKAEDERLNLY
CCCCCCCCCHHHHHHCCCHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCCCCCEEEE
FK
EC
>Mature Secondary Structure
MKSHKTRLTILFSFLCILFCILIGRVVFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCHHHHHHHCCCCCCEEEE
TVDSATIGIYPANIYDPNFTAVQLAPYLDMPPEKIEAMIREKSRYFLLKREIDESLGNKI
EECCEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
MELSLPGVRREKEYKRVYPHGNLASSLVGFTGMDDDRALSGLEVQYNQELMTPTESDSSR
EEECCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCEEEECCHHCCCCCCCCCC
GSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMDINTGKILASASFPAFDPNQYNE
CCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCC
SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRPDEKFHCPGYVELGKTKIKCTNAH
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCEEEEEECCC
GHLNLEEILQYSCNVGIIKASQRIPEALLYDYMKKFQFGEKTGFLPNESAGYFPPLKKWT
CCCCHHHHHHHHCCCEEEECCHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PATSMFMAIGQGISVTPIQLVASAASVANGGRMLTPRVVSHFSDSYGAILHEFKTQETPI
CHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHCCHHHHHHHHHHCCCCCC
GIREYTTEKILKAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAISGKGYVEGLWSASFLG
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKHFQR
CCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
KNLKGTNVGEIPNLIGKSKREALEILRPSGIPVKFHGSGFCYKQEPDPGKKAEDERLNLY
CCCCCCCCCHHHHHHCCCHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCCCCCEEEE
FK
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]