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The map label for this gene is hrcA

Identifier: 116329213

GI number: 116329213

Start: 3138907

End: 3139935

Strand: Reverse

Name: hrcA

Synonym: LBL_2646

Alternate gene names: 116329213

Gene position: 3139935-3138907 (Counterclockwise)

Preceding gene: 116329221

Following gene: 116329212

Centisome position: 86.87

GC content: 41.69

Gene sequence:

>1029_bases
ATGGATCTCACAGAACGTCATAAAAGAATTCTAAAAGCCCTTGTAGACGAGTTTATCCAGGAGAATCGTCCTGTAGGTTC
GAAAACCCTTTTTGATAAACACGATATTGGACTTTCTCCTGCTTCGATCCGAACCGTGCTGAAGGATTTGGAAGATTACG
GTTATCTTGCGTCCAAACATACTTCGGGTGGGAGAATTCCTACGGAAAGGGGATATCGTTTTTATGTAGATTCGCTGGTA
ATTCTATACGAGCTGACTCTCAAAGAAAAACAACGGATCCAACAAGAATATCTGAAGATGCAGTTTAAACTCGATCAAAT
TTTGAAGGCTACCGCTTCGGTGCTTTCTTCCCTGTCCAATGCGGCGGGAATTGTGATCGGTCCGGCGAAAAATTTGGACA
CTCTAAAACATCTCGAATTGATCCACGTCCGTGGAGACGAGATATTGATGATTCTCGTGATGAGATCCGGAACCGTTCTG
CACAGAAATATTTTCGTAGATCGGAATTATTCCCAGGAAGCCTTGTATCAAGTCTCTAAATATCTGAACGACAATTTGAA
AGGTTATGATATATACGAAATTCAGAATGTAGTCGTTCCGAATCTTATGGTTCGAAGAGATGGACCCGAGGATTTTACAA
GAATTGCGGAACTATTATCTTCCGCTATGAACCCGGATAATTCCGAAGTTACTTTGTATATAGACGGATTTAAGAATCTT
TACGCGAATTTTAGGGACGAAGAACAACAACTTTCTCAAGTCCTTTCTCTTTTAGACGATCAGGGATTTTTGAAGGAATT
TTTTTCCGAGTACATCGATCAGGACGGAGTATATACGATCATAGGAAAAGACGGGAATCGAAGTATGTCCGGCGTTTCCA
TCATCACTTCCAACTATAAGATGGGGGAAAAGAAGATCGGAGCATTGGGAATCATAGGACCGCAGAGAATGGATTACAAC
AGAGCCTTACCGCTCGTCGACTTTACGTCGAAACTCGTCTCCGAAATGGTGACTCGCATTAGTAAATAA

Upstream 100 bases:

>100_bases
CTCAAAACAAGATGAAACTACTTTCTTCCTTGACATTTTTCGTAGGAATTCGGAAACTAATTGTATGAATTAGCACTCTA
ACATTCAGAGTGCCAGAAAA

Downstream 100 bases:

>100_bases
GGGAGAGTAATGTATGGCCGAAACATCGAATTCGGAAAATAAAACTTCGGAAGAAGCAAAGGCCAGCGAGAAAAATTCTC
GGTCAATAACATTAGAGGAA

Product: heat-inducible transcriptional repressor, HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDYGYLASKHTSGGRIPTERGYRFYVDSLV
ILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSNAAGIVIGPAKNLDTLKHLELIHVRGDEILMILVMRSGTVL
HRNIFVDRNYSQEALYQVSKYLNDNLKGYDIYEIQNVVVPNLMVRRDGPEDFTRIAELLSSAMNPDNSEVTLYIDGFKNL
YANFRDEEQQLSQVLSLLDDQGFLKEFFSEYIDQDGVYTIIGKDGNRSMSGVSIITSNYKMGEKKIGALGIIGPQRMDYN
RALPLVDFTSKLVSEMVTRISK

Sequences:

>Translated_342_residues
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDYGYLASKHTSGGRIPTERGYRFYVDSLV
ILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSNAAGIVIGPAKNLDTLKHLELIHVRGDEILMILVMRSGTVL
HRNIFVDRNYSQEALYQVSKYLNDNLKGYDIYEIQNVVVPNLMVRRDGPEDFTRIAELLSSAMNPDNSEVTLYIDGFKNL
YANFRDEEQQLSQVLSLLDDQGFLKEFFSEYIDQDGVYTIIGKDGNRSMSGVSIITSNYKMGEKKIGALGIIGPQRMDYN
RALPLVDFTSKLVSEMVTRISK
>Mature_342_residues
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDYGYLASKHTSGGRIPTERGYRFYVDSLV
ILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSNAAGIVIGPAKNLDTLKHLELIHVRGDEILMILVMRSGTVL
HRNIFVDRNYSQEALYQVSKYLNDNLKGYDIYEIQNVVVPNLMVRRDGPEDFTRIAELLSSAMNPDNSEVTLYIDGFKNL
YANFRDEEQQLSQVLSLLDDQGFLKEFFSEYIDQDGVYTIIGKDGNRSMSGVSIITSNYKMGEKKIGALGIIGPQRMDYN
RALPLVDFTSKLVSEMVTRISK

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_LEPBJ (Q04VD0)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_799898.1
- STRING:   Q04VD0
- GeneID:   4409331
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_0431
- eggNOG:   COG1420
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   CLSK574955
- BioCyc:   LBOR355277:LBJ_0431-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 38981; Mature: 38981

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDYGYLASKH
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCC
TSGGRIPTERGYRFYVDSLVILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AAGIVIGPAKNLDTLKHLELIHVRGDEILMILVMRSGTVLHRNIFVDRNYSQEALYQVSK
CCEEEEECCCCCHHHHHHHEEEECCCCEEEEEEECCCCEEEEEEEEECCCCHHHHHHHHH
YLNDNLKGYDIYEIQNVVVPNLMVRRDGPEDFTRIAELLSSAMNPDNSEVTLYIDGFKNL
HHCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHH
YANFRDEEQQLSQVLSLLDDQGFLKEFFSEYIDQDGVYTIIGKDGNRSMSGVSIITSNYK
HHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCC
MGEKKIGALGIIGPQRMDYNRALPLVDFTSKLVSEMVTRISK
CCCHHCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDYGYLASKH
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCC
TSGGRIPTERGYRFYVDSLVILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AAGIVIGPAKNLDTLKHLELIHVRGDEILMILVMRSGTVLHRNIFVDRNYSQEALYQVSK
CCEEEEECCCCCHHHHHHHEEEECCCCEEEEEEECCCCEEEEEEEEECCCCHHHHHHHHH
YLNDNLKGYDIYEIQNVVVPNLMVRRDGPEDFTRIAELLSSAMNPDNSEVTLYIDGFKNL
HHCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHH
YANFRDEEQQLSQVLSLLDDQGFLKEFFSEYIDQDGVYTIIGKDGNRSMSGVSIITSNYK
HHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCC
MGEKKIGALGIIGPQRMDYNRALPLVDFTSKLVSEMVTRISK
CCCHHCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA