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The map label for this gene is mraW [H]

Identifier: 116329171

GI number: 116329171

Start: 3073444

End: 3074394

Strand: Direct

Name: mraW [H]

Synonym: LBL_2598

Alternate gene names: 116329171

Gene position: 3073444-3074394 (Clockwise)

Preceding gene: 116329169

Following gene: 116329172

Centisome position: 85.03

GC content: 40.48

Gene sequence:

>951_bases
TTGGAACCGGTTCATTATTCAGTTCAGGGAAATAACATTCTTCAAATTTTTACGGAGAATTTCCATAAAGAAGATCCTGT
TTTATTCTTGGACGGAACCGCCGGAGAAGGCGGACATAGTCTTTTATTTTTAAAAGGATTTCCAAATTCCAAAGTTATAC
TTTGCGACAGGGATCCGGTGATGTTGTCAAGGGCTCTTGCAAGACTCGTTGACTTCAAAGAAAGGGTGGTTTCGATTCAA
ACGAACTTTTCCGAGATCGATTCGAATCTTTTAAGTTCACACGGTATCAATGATTCTCCGCAAGGAATTCTTTTAGATTT
AGGAATTTCAACATTTCATCTTTTTCATTCTGGAAGAGGTTTCAGTTTTAAAGAAGCCGAACCCTTAGACATGAGACTGA
CTCCGAACATTGGGATAAACGCGGAGGACGTAATCAACACGTATTCCAAAGACAGGTTGATGCACATCTTTTATACGTAC
GGAGAAGAACGTTGGTCTAAGAAGATCGCGGAAGTCATCGTAGAAAGAAGAAAACAAAATTTGATTTCTTACACCTCCGA
ACTTGCGGATCTTATTTCCAAAATCATCCCGCGTAAACTTTGGCCTCCGGGAAGACATCCTGCAACTCGGATTTTTCAAG
CGCTCCGGATCGAAGTCAATCAAGAGTTGACTCATATCGAAAAGGGACTGGATTCCCTCTTAAATCTTCTGCGCCCGGAA
GGTGTGATTCAAGTGATCTCCTTTCATTCTTTGGAAGACAGGATCGTCAAAAATTCTCTTCGAAATTACGCGAAACAAAA
CGGATTCGAACTTCTTACCAAAAAACCGATTCTCCCTTCCGAAGAGGAAACTAAGGAGAATCCGGCTTCCCGTTCCGCAA
AATTGAGAGTTCTCAGAAAAACGAAATCAGCCGATAAAAAATATAAAAAGGAAAATTCCAAGGAAGAATAA

Upstream 100 bases:

>100_bases
AATTTGATTCTTCCATCGGTCCTAGAATAATTTCTCGTTCCTTTGTGTCAAAATAGAATCTCCTTGCAGGACCGACACTT
TGGAAAAGAATGGAAGCAGA

Downstream 100 bases:

>100_bases
ATGTCGTCGTTTTCCACATTTCTCAACCGTCCCGTTTGGAAGGACCTTGGAATTTTATTTTCGAGTTTAGGTAAGGTGAT
TTTTCCTTTAAGTTTATTTT

Product: S-adenosylmethionine-dependentmethyltransferase

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MEPVHYSVQGNNILQIFTENFHKEDPVLFLDGTAGEGGHSLLFLKGFPNSKVILCDRDPVMLSRALARLVDFKERVVSIQ
TNFSEIDSNLLSSHGINDSPQGILLDLGISTFHLFHSGRGFSFKEAEPLDMRLTPNIGINAEDVINTYSKDRLMHIFYTY
GEERWSKKIAEVIVERRKQNLISYTSELADLISKIIPRKLWPPGRHPATRIFQALRIEVNQELTHIEKGLDSLLNLLRPE
GVIQVISFHSLEDRIVKNSLRNYAKQNGFELLTKKPILPSEEETKENPASRSAKLRVLRKTKSADKKYKKENSKEE

Sequences:

>Translated_316_residues
MEPVHYSVQGNNILQIFTENFHKEDPVLFLDGTAGEGGHSLLFLKGFPNSKVILCDRDPVMLSRALARLVDFKERVVSIQ
TNFSEIDSNLLSSHGINDSPQGILLDLGISTFHLFHSGRGFSFKEAEPLDMRLTPNIGINAEDVINTYSKDRLMHIFYTY
GEERWSKKIAEVIVERRKQNLISYTSELADLISKIIPRKLWPPGRHPATRIFQALRIEVNQELTHIEKGLDSLLNLLRPE
GVIQVISFHSLEDRIVKNSLRNYAKQNGFELLTKKPILPSEEETKENPASRSAKLRVLRKTKSADKKYKKENSKEE
>Mature_316_residues
MEPVHYSVQGNNILQIFTENFHKEDPVLFLDGTAGEGGHSLLFLKGFPNSKVILCDRDPVMLSRALARLVDFKERVVSIQ
TNFSEIDSNLLSSHGINDSPQGILLDLGISTFHLFHSGRGFSFKEAEPLDMRLTPNIGINAEDVINTYSKDRLMHIFYTY
GEERWSKKIAEVIVERRKQNLISYTSELADLISKIIPRKLWPPGRHPATRIFQALRIEVNQELTHIEKGLDSLLNLLRPE
GVIQVISFHSLEDRIVKNSLRNYAKQNGFELLTKKPILPSEEETKENPASRSAKLRVLRKTKSADKKYKKENSKEE

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=316, Percent_Identity=33.2278481012658, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI165377202, Length=173, Percent_Identity=33.5260115606936, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1786270, Length=294, Percent_Identity=38.7755102040816, Blast_Score=186, Evalue=2e-48,
Organism=Drosophila melanogaster, GI62472493, Length=311, Percent_Identity=36.6559485530547, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28571637, Length=311, Percent_Identity=36.6559485530547, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 36106; Mature: 36106

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPVHYSVQGNNILQIFTENFHKEDPVLFLDGTAGEGGHSLLFLKGFPNSKVILCDRDPV
CCCCEEEECCCCEEEEEEHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHH
MLSRALARLVDFKERVVSIQTNFSEIDSNLLSSHGINDSPQGILLDLGISTFHLFHSGRG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHCCCC
FSFKEAEPLDMRLTPNIGINAEDVINTYSKDRLMHIFYTYGEERWSKKIAEVIVERRKQN
CCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LISYTSELADLISKIIPRKLWPPGRHPATRIFQALRIEVNQELTHIEKGLDSLLNLLRPE
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVIQVISFHSLEDRIVKNSLRNYAKQNGFELLTKKPILPSEEETKENPASRSAKLRVLRK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHCCCCCCCCHHHHCCCCCHHHHHHHHHHH
TKSADKKYKKENSKEE
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEPVHYSVQGNNILQIFTENFHKEDPVLFLDGTAGEGGHSLLFLKGFPNSKVILCDRDPV
CCCCEEEECCCCEEEEEEHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHH
MLSRALARLVDFKERVVSIQTNFSEIDSNLLSSHGINDSPQGILLDLGISTFHLFHSGRG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHCCCC
FSFKEAEPLDMRLTPNIGINAEDVINTYSKDRLMHIFYTYGEERWSKKIAEVIVERRKQN
CCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LISYTSELADLISKIIPRKLWPPGRHPATRIFQALRIEVNQELTHIEKGLDSLLNLLRPE
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVIQVISFHSLEDRIVKNSLRNYAKQNGFELLTKKPILPSEEETKENPASRSAKLRVLRK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHCCCCCCCCHHHHCCCCCHHHHHHHHHHH
TKSADKKYKKENSKEE
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA