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The map label for this gene is coaX

Identifier: 116329161

GI number: 116329161

Start: 3063022

End: 3063795

Strand: Reverse

Name: coaX

Synonym: LBL_2588

Alternate gene names: 116329161

Gene position: 3063795-3063022 (Counterclockwise)

Preceding gene: 116329162

Following gene: 116329154

Centisome position: 84.77

GC content: 42.64

Gene sequence:

>774_bases
ATGCTTCTAGTCGTCGATGTGGGTAATACGAATACCGTCTTTGGGATTTTCGAAAACGGAAAAAACGTTCCTCTGTTTCA
TAAACGAACCGTAACCAGGAAAGACAGAACATCCGATGAACTCGGATTGTTCTTCAGAGGGTTTTTGAGGGAATTTAAAA
TCGAAAATGAAGCGATCACAGGAGGAATTTATTCCAGCGTTGTGCCGACATTAAATCCGATCTTAGAGAGAATGTTCCAG
GATTGGTTTAAGATTGAAGCGATTCGAGTTCATTATCAGATGAAACTTCCTTTTTCGATTTCTTATCCGAGGCCTTATGA
AATTGGAGCCGACCGACTTGTAAATGCCGCGGCTTGTGTGATCGATTCGCCCGGCAAATTCATCATTATCGATTTAGGGA
CTGCGACCACGTTTTGTGTAGTGAGTGAAAAACCCGAGTATCTTGGAGGAGTCATTGCACCAGGTTTGAAAGTTTCTATG
GACGCTTTGACAAGAAACACTTCTCAACTTCCTCCTATCGTTTTTCAGTCTCCCGAAAAAATTTTGGGGGATTCTACGAT
CGAATCGATTCAGGCCGGGTTCTTTTTCGGTTGGATTGGCCTTCTGGAAGGTATTATTCGTGAAATCAAAAAAGATAAAG
GCCAGGATTATCGTGTAATCGGAACCGGAGGGTTGGTGACTGTCATCGACGCCGCTCATCCGGGAATCTTCGATAAAATC
GATCCACTTTTGACTTTACGAGGATTGCAGATTTTACACCAAATGAATTCTTAG

Upstream 100 bases:

>100_bases
GAGGGACTTAATGAAAACGGTTCCTTAATCTTAAAAACTCCTTCCGGGATTAAGTTGGATTTCATGGATAGTCCCGAGGA
CTTCCGCTCCCTAAATTAAA

Downstream 100 bases:

>100_bases
AATTTGTTTTGCTCTCTCGGAGAGCCGGGATTGCAAGTCCATCTATTCACAAACCGCCTGAAAAAGAATTTTTTCGAAGC
GGTTTTGAAAAATCGAATTC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLLVVDVGNTNTVFGIFENGKNVPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEAITGGIYSSVVPTLNPILERMFQ
DWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAAACVIDSPGKFIIIDLGTATTFCVVSEKPEYLGGVIAPGLKVSM
DALTRNTSQLPPIVFQSPEKILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYRVIGTGGLVTVIDAAHPGIFDKI
DPLLTLRGLQILHQMNS

Sequences:

>Translated_257_residues
MLLVVDVGNTNTVFGIFENGKNVPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEAITGGIYSSVVPTLNPILERMFQ
DWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAAACVIDSPGKFIIIDLGTATTFCVVSEKPEYLGGVIAPGLKVSM
DALTRNTSQLPPIVFQSPEKILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYRVIGTGGLVTVIDAAHPGIFDKI
DPLLTLRGLQILHQMNS
>Mature_257_residues
MLLVVDVGNTNTVFGIFENGKNVPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEAITGGIYSSVVPTLNPILERMFQ
DWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAAACVIDSPGKFIIIDLGTATTFCVVSEKPEYLGGVIAPGLKVSM
DALTRNTSQLPPIVFQSPEKILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYRVIGTGGLVTVIDAAHPGIFDKI
DPLLTLRGLQILHQMNS

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_LEPBJ (Q04V79)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_799949.1
- ProteinModelPortal:   Q04V79
- SMR:   Q04V79
- STRING:   Q04V79
- GeneID:   4409391
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_0491
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   LBOR355277:LBJ_0491-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28565; Mature: 28565

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: ACT_SITE 111-111 BINDING 102-102 BINDING 134-134 BINDING 186-186

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVVDVGNTNTVFGIFENGKNVPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEAIT
CEEEEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GGIYSSVVPTLNPILERMFQDWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAAACV
CHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCEEECCCCCCCCCHHHHHHHHEEE
IDSPGKFIIIDLGTATTFCVVSEKPEYLGGVIAPGLKVSMDALTRNTSQLPPIVFQSPEK
EECCCCEEEEEECCCEEEEEECCCCHHHCCEECCCCEEEHHHHHCCCCCCCCEEECCCHH
ILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYRVIGTGGLVTVIDAAHPGIFDKI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCHHHH
DPLLTLRGLQILHQMNS
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLVVDVGNTNTVFGIFENGKNVPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEAIT
CEEEEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GGIYSSVVPTLNPILERMFQDWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAAACV
CHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCEEECCCCCCCCCHHHHHHHHEEE
IDSPGKFIIIDLGTATTFCVVSEKPEYLGGVIAPGLKVSMDALTRNTSQLPPIVFQSPEK
EECCCCEEEEEECCCEEEEEECCCCHHHCCEECCCCEEEHHHHHCCCCCCCCEEECCCHH
ILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYRVIGTGGLVTVIDAAHPGIFDKI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCHHHH
DPLLTLRGLQILHQMNS
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA