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The map label for this gene is 116329043

Identifier: 116329043

GI number: 116329043

Start: 2900060

End: 2901484

Strand: Direct

Name: 116329043

Synonym: LBL_2449

Alternate gene names: NA

Gene position: 2900060-2901484 (Clockwise)

Preceding gene: 116329042

Following gene: 116329044

Centisome position: 80.24

GC content: 44.07

Gene sequence:

>1425_bases
GTGATCGCTGCAGCGGGCAAAGGAACGCGGGCCTATCCCAGAACGACATACATTCCCAAACCCTTATTCGAATTTCAGGG
AAAAACGATCCTCGAACGAAACGTCGAGCTGATGCAGAGTACGTTCCGTGTTAAAAAAATTTATATTATAGTCGGCCACC
TCAAAGAAATGGTACTTTCCGAAATCGAAAAAATTCGGAAAAATCATCGGGATGTAGAAATTATACCTTCCCCTTGGACC
ACTAAGGGCCTTGCAAGCGATATCGCAAGTTTAGAACCGCAGATTCATTCTCCATTTATCACGATTCTCGGAGACGAATT
CTACTTCTATCCGGATCATAAAAAGTTCATACAGACACTCCGAAAACATCCAAAACTCATCGCCTCGATCGGAGTCCAAA
AAACTTCTTTTCTTTCCAGAATCCGAAAAAATTATTCCGTGGAATTACAAGAGGATCGAATCTTAGAACTCGTGGAAAAA
CCTTCCGACCCTCCGAACAATCTCCTCGGTCTGGGAAGCTATCTTTTTACTCCCGCTTATTTCGAATATTTTAAACAAAC
TCCTCCTTCGGCCAAAAATGGAATCATCGAGATCACGGACGTAATCGATCTGATGGCAAAAAAAAGCCGCAAGGTTTTCG
CGACGGAACTCAACGTGGAATATTTCAATATCAATTCCATGCAAGACTACCACCATGCGGTTTATGAGATCCGAAACGAG
GAATTCGCACGTTTTAAGACTACGTTGATTGTCCCCACAAAAAACAACGAAAGATCCATCGCGGACGTGATCGTGGATTT
CCGGGGAAAGGTGGACGAAATTTTGATCGTAGACTCCGGCTCCACGGATAAAACATTAGAAATTACTAAAAAAGAAAAAG
CGAAAATTATTTCCTGTAAAACCAAAGGTGACGAGGATCATTTCGGAAAACAGATTCGGGAAGGAATCCGGGCCGCATCC
GGAGATATCGCGATCGTCATAACCCCCGACGGATCATATCGTTCTAAGGATTATCCGAAACTTTTGGAATATCTCAAGGA
CTCCGATATGGTAATCGGGACCCGAACCACAAGGCAGATGATCGAACAAGGATCCAACTTACTCCCCGGACTCCGTGTGG
CCAATCTGATACTCGGAAAACTCATCGAGATTTTTTGGTGGGGAATGGAGCCGCGCTTTACGGACGCGATGTGTTCTTAC
TTTGCGATCTGGAAAGATTCTTACTCTAAAATCGAACCGGATCTAGAGATGAATGACCGGAGAGTCATTCCTGAACTGAT
GATGGAAACCGTTCGTTCGTACATGCGTTGTATTGAAATTCCGATTTCCTATTATCGCCCGATCGAGTCCGTTCCCAAAA
ACACGACCCGAGAGTTCCTTTCAATCGTTCGTTTGATGCTGAAGAAAAAATGGCTCGGAATCTAA

Upstream 100 bases:

>100_bases
ACTATACGGTGTGTTGAAAAAATCTTTTTCTAAATCGTTTTTGACATCCTTAGGCCTCTAAAAATAGCATATCCCCTAAG
TGGCAAATATTGAAATAGGT

Downstream 100 bases:

>100_bases
TTTAGAATTTTATAATTATACAATATTAAAAAGGGATATTTATGGCAAAAAAAGTTTTAGTGACGGGCGGGTGCGGATTT
CTGGGCTCCCACGTTTGTGA

Product: bifunctional glycosyltransferase/sugar pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MIAAAGKGTRAYPRTTYIPKPLFEFQGKTILERNVELMQSTFRVKKIYIIVGHLKEMVLSEIEKIRKNHRDVEIIPSPWT
TKGLASDIASLEPQIHSPFITILGDEFYFYPDHKKFIQTLRKHPKLIASIGVQKTSFLSRIRKNYSVELQEDRILELVEK
PSDPPNNLLGLGSYLFTPAYFEYFKQTPPSAKNGIIEITDVIDLMAKKSRKVFATELNVEYFNINSMQDYHHAVYEIRNE
EFARFKTTLIVPTKNNERSIADVIVDFRGKVDEILIVDSGSTDKTLEITKKEKAKIISCKTKGDEDHFGKQIREGIRAAS
GDIAIVITPDGSYRSKDYPKLLEYLKDSDMVIGTRTTRQMIEQGSNLLPGLRVANLILGKLIEIFWWGMEPRFTDAMCSY
FAIWKDSYSKIEPDLEMNDRRVIPELMMETVRSYMRCIEIPISYYRPIESVPKNTTREFLSIVRLMLKKKWLGI

Sequences:

>Translated_474_residues
MIAAAGKGTRAYPRTTYIPKPLFEFQGKTILERNVELMQSTFRVKKIYIIVGHLKEMVLSEIEKIRKNHRDVEIIPSPWT
TKGLASDIASLEPQIHSPFITILGDEFYFYPDHKKFIQTLRKHPKLIASIGVQKTSFLSRIRKNYSVELQEDRILELVEK
PSDPPNNLLGLGSYLFTPAYFEYFKQTPPSAKNGIIEITDVIDLMAKKSRKVFATELNVEYFNINSMQDYHHAVYEIRNE
EFARFKTTLIVPTKNNERSIADVIVDFRGKVDEILIVDSGSTDKTLEITKKEKAKIISCKTKGDEDHFGKQIREGIRAAS
GDIAIVITPDGSYRSKDYPKLLEYLKDSDMVIGTRTTRQMIEQGSNLLPGLRVANLILGKLIEIFWWGMEPRFTDAMCSY
FAIWKDSYSKIEPDLEMNDRRVIPELMMETVRSYMRCIEIPISYYRPIESVPKNTTREFLSIVRLMLKKKWLGI
>Mature_474_residues
MIAAAGKGTRAYPRTTYIPKPLFEFQGKTILERNVELMQSTFRVKKIYIIVGHLKEMVLSEIEKIRKNHRDVEIIPSPWT
TKGLASDIASLEPQIHSPFITILGDEFYFYPDHKKFIQTLRKHPKLIASIGVQKTSFLSRIRKNYSVELQEDRILELVEK
PSDPPNNLLGLGSYLFTPAYFEYFKQTPPSAKNGIIEITDVIDLMAKKSRKVFATELNVEYFNINSMQDYHHAVYEIRNE
EFARFKTTLIVPTKNNERSIADVIVDFRGKVDEILIVDSGSTDKTLEITKKEKAKIISCKTKGDEDHFGKQIREGIRAAS
GDIAIVITPDGSYRSKDYPKLLEYLKDSDMVIGTRTTRQMIEQGSNLLPGLRVANLILGKLIEIFWWGMEPRFTDAMCSY
FAIWKDSYSKIEPDLEMNDRRVIPELMMETVRSYMRCIEIPISYYRPIESVPKNTTREFLSIVRLMLKKKWLGI

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 54777; Mature: 54777

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAAGKGTRAYPRTTYIPKPLFEFQGKTILERNVELMQSTFRVKKIYIIVGHLKEMVLS
CCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHH
EIEKIRKNHRDVEIIPSPWTTKGLASDIASLEPQIHSPFITILGDEFYFYPDHKKFIQTL
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEECCHHHHHHHH
RKHPKLIASIGVQKTSFLSRIRKNYSVELQEDRILELVEKPSDPPNNLLGLGSYLFTPAY
HHCHHHHHHHCCHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
FEYFKQTPPSAKNGIIEITDVIDLMAKKSRKVFATELNVEYFNINSMQDYHHAVYEIRNE
HHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCEEEEEEEEEEEECCCHHHHHHHHHHHCCH
EFARFKTTLIVPTKNNERSIADVIVDFRGKVDEILIVDSGSTDKTLEITKKEKAKIISCK
HHHEEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEE
TKGDEDHFGKQIREGIRAASGDIAIVITPDGSYRSKDYPKLLEYLKDSDMVIGTRTTRQM
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEEEECHHHHHH
IEQGSNLLPGLRVANLILGKLIEIFWWGMEPRFTDAMCSYFAIWKDSYSKIEPDLEMNDR
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RVIPELMMETVRSYMRCIEIPISYYRPIESVPKNTTREFLSIVRLMLKKKWLGI
HHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIAAAGKGTRAYPRTTYIPKPLFEFQGKTILERNVELMQSTFRVKKIYIIVGHLKEMVLS
CCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHH
EIEKIRKNHRDVEIIPSPWTTKGLASDIASLEPQIHSPFITILGDEFYFYPDHKKFIQTL
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEECCHHHHHHHH
RKHPKLIASIGVQKTSFLSRIRKNYSVELQEDRILELVEKPSDPPNNLLGLGSYLFTPAY
HHCHHHHHHHCCHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
FEYFKQTPPSAKNGIIEITDVIDLMAKKSRKVFATELNVEYFNINSMQDYHHAVYEIRNE
HHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCEEEEEEEEEEEECCCHHHHHHHHHHHCCH
EFARFKTTLIVPTKNNERSIADVIVDFRGKVDEILIVDSGSTDKTLEITKKEKAKIISCK
HHHEEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEE
TKGDEDHFGKQIREGIRAASGDIAIVITPDGSYRSKDYPKLLEYLKDSDMVIGTRTTRQM
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEEEECHHHHHH
IEQGSNLLPGLRVANLILGKLIEIFWWGMEPRFTDAMCSYFAIWKDSYSKIEPDLEMNDR
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RVIPELMMETVRSYMRCIEIPISYYRPIESVPKNTTREFLSIVRLMLKKKWLGI
HHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA