Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 116329021

GI number: 116329021

Start: 2876433

End: 2877005

Strand: Reverse

Name: coaE [H]

Synonym: LBL_2426

Alternate gene names: 116329021

Gene position: 2877005-2876433 (Counterclockwise)

Preceding gene: 116329022

Following gene: 116329020

Centisome position: 79.6

GC content: 40.84

Gene sequence:

>573_bases
ATGATCGGAGGAGGTAAAAGTACTGTCGTAAAGATTTTGGAAGAATTGGGAGGTTTTGGGATCAGTGCTGATCGTTTAGC
GAAACGTTATACGGAAATAGACTCTCCTATTCTTCCGGAGCTCGTGGGACTCTTAGGAAAAGGAATTTTGGATTCGGAAG
GAAAGCCGAACCGAAAAAAAATTTCCGATATCGTTTTCAACGACGCTGAAAAACTTGCGGGACTCAATCGTTTGATTCAT
CCCAAGGTTCGCGAGGATTTTCAAAAAATTTTGAAAACTCAAGCTCGAGGGAAAATTGTGATTTGGGAAGTTCCCCTTTT
ATTCGAGACCGACGCTTATACGCTTTGTAACGCGACTGTAGCCGTGGACTCCGATCCGGAAGAATCGATTTTGAGGACGA
TTTCGAGAGATAGACTTAAAAAAGAAGACGTTTTGGCGAGGATCTCGAGTCAACTTCCTATTACGGAAAAACTGAAAAGA
GCCGATTATATCATTAGGAACAAAGGAAACTTGGAGACTCTCAAGGAAGAATGTAAAAATCTTTATTCCACTCTATTGGA
AAAAATGTTATGA

Upstream 100 bases:

>100_bases
AGTTTCTTTTTTGCTTGTACTTTTGTCCCGGTGTTTTATCCTTCAACGTATGCAGAGTTCCGACTCCGGTAAAGAGGCCT
TTTTGGTTGGGATTACCGGA

Downstream 100 bases:

>100_bases
AAGAAAAAATTTTTTATGTAATCAATCTGGATAATAAGAGAATCCTAATTCTCTCTACGTTTTTAATCGGACTACTATTC
TCTTTTTTTTTCTTAGGAGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIGGGKSTVVKILEELGGFGISADRLAKRYTEIDSPILPELVGLLGKGILDSEGKPNRKKISDIVFNDAEKLAGLNRLIH
PKVREDFQKILKTQARGKIVIWEVPLLFETDAYTLCNATVAVDSDPEESILRTISRDRLKKEDVLARISSQLPITEKLKR
ADYIIRNKGNLETLKEECKNLYSTLLEKML

Sequences:

>Translated_190_residues
MIGGGKSTVVKILEELGGFGISADRLAKRYTEIDSPILPELVGLLGKGILDSEGKPNRKKISDIVFNDAEKLAGLNRLIH
PKVREDFQKILKTQARGKIVIWEVPLLFETDAYTLCNATVAVDSDPEESILRTISRDRLKKEDVLARISSQLPITEKLKR
ADYIIRNKGNLETLKEECKNLYSTLLEKML
>Mature_190_residues
MIGGGKSTVVKILEELGGFGISADRLAKRYTEIDSPILPELVGLLGKGILDSEGKPNRKKISDIVFNDAEKLAGLNRLIH
PKVREDFQKILKTQARGKIVIWEVPLLFETDAYTLCNATVAVDSDPEESILRTISRDRLKKEDVLARISSQLPITEKLKR
ADYIIRNKGNLETLKEECKNLYSTLLEKML

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=187, Percent_Identity=32.0855614973262, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI191252795, Length=187, Percent_Identity=32.0855614973262, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1786292, Length=186, Percent_Identity=30.1075268817204, Blast_Score=91, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=188, Percent_Identity=31.9148936170213, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320402, Length=187, Percent_Identity=31.0160427807487, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644728, Length=187, Percent_Identity=27.807486631016, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24658602, Length=192, Percent_Identity=23.9583333333333, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21320; Mature: 21320

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGGGKSTVVKILEELGGFGISADRLAKRYTEIDSPILPELVGLLGKGILDSEGKPNRKK
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHH
ISDIVFNDAEKLAGLNRLIHPKVREDFQKILKTQARGKIVIWEVPLLFETDAYTLCNATV
HHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCHHHHCCEE
AVDSDPEESILRTISRDRLKKEDVLARISSQLPITEKLKRADYIIRNKGNLETLKEECKN
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LYSTLLEKML
HHHHHHHHHC
>Mature Secondary Structure
MIGGGKSTVVKILEELGGFGISADRLAKRYTEIDSPILPELVGLLGKGILDSEGKPNRKK
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHH
ISDIVFNDAEKLAGLNRLIHPKVREDFQKILKTQARGKIVIWEVPLLFETDAYTLCNATV
HHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCHHHHCCEE
AVDSDPEESILRTISRDRLKKEDVLARISSQLPITEKLKRADYIIRNKGNLETLKEECKN
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LYSTLLEKML
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA