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The map label for this gene is purQ [H]

Identifier: 116328977

GI number: 116328977

Start: 2822944

End: 2823603

Strand: Reverse

Name: purQ [H]

Synonym: LBL_2379

Alternate gene names: 116328977

Gene position: 2823603-2822944 (Counterclockwise)

Preceding gene: 116328978

Following gene: 116328976

Centisome position: 78.12

GC content: 46.06

Gene sequence:

>660_bases
ATGAAAGTTGCGATCGTTACTTTTCCGGGCTCCAATTGCGATTCGGATATCTTTCGCGTTTTGAGGGATCAATACGAAGC
GGAAGTGGATCGAGTTTGGCACAGGGATCAGCTCGATAAAAAATACGAACTCGTGATTCTTCCGGGAGGTTTTTCTTACG
GAGATTATCTTCGTTCCGGCGCGATGGCGGGTTTTTCTCCGGTGATGAAGTCGGTTAAGGAACACGTGAATAAAGGCGGA
AAACTTTTCGGGATCTGCAACGGCTTTCAAATTCTTACGGAAGCGGAATTCCTACCCGGGGCTCTCACAAGAAATAAAAC
CCTCAAATACATCTGCAAAACCGTGATCTTGAAAAAAGGTTCTTCCGGAAATCCGGTGACTGCGTCTCTCGATTCTCGAA
AAGAATTGAAAATTCCGATCGCTCACGCGGACGGCTGTTATTATGCGACATCGGACGTTATCAAACAACTCGAAGACGAA
GAGAGAATTTTATTCCGTTATTTCGGAGAAAATCCGAACGGTTCTCTCCAAGCGATCGCAGGAATCACGTCCAAAAATTT
TAAGGTCGCCGGAATGATGCCTCACCCGGAAAGGGCGATGAATCCGGTGATCGGTGAAGTCGATGGAAAGATTGTTCTAG
ATTTGATTTTGAGCGCTTGA

Upstream 100 bases:

>100_bases
CTCCGAACGAAGAAACGGCTAGAAAGGATGTGGAAAGACTTTGCGATAAGATTCTCGTCAATCACGTTATAGAAACATAT
TCTGCGAATATTCAAAAAAT

Downstream 100 bases:

>100_bases
ATTTACAAGAGTAAACAAATTCGTTTGAATTTTCGTGTTCATTTTTTAGATATATGATTCAATACTAAAAGCCCGTCTCA
AAACTGTCTTCTGTAGGAGC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKVAIVTFPGSNCDSDIFRVLRDQYEAEVDRVWHRDQLDKKYELVILPGGFSYGDYLRSGAMAGFSPVMKSVKEHVNKGG
KLFGICNGFQILTEAEFLPGALTRNKTLKYICKTVILKKGSSGNPVTASLDSRKELKIPIAHADGCYYATSDVIKQLEDE
ERILFRYFGENPNGSLQAIAGITSKNFKVAGMMPHPERAMNPVIGEVDGKIVLDLILSA

Sequences:

>Translated_219_residues
MKVAIVTFPGSNCDSDIFRVLRDQYEAEVDRVWHRDQLDKKYELVILPGGFSYGDYLRSGAMAGFSPVMKSVKEHVNKGG
KLFGICNGFQILTEAEFLPGALTRNKTLKYICKTVILKKGSSGNPVTASLDSRKELKIPIAHADGCYYATSDVIKQLEDE
ERILFRYFGENPNGSLQAIAGITSKNFKVAGMMPHPERAMNPVIGEVDGKIVLDLILSA
>Mature_219_residues
MKVAIVTFPGSNCDSDIFRVLRDQYEAEVDRVWHRDQLDKKYELVILPGGFSYGDYLRSGAMAGFSPVMKSVKEHVNKGG
KLFGICNGFQILTEAEFLPGALTRNKTLKYICKTVILKKGSSGNPVTASLDSRKELKIPIAHADGCYYATSDVIKQLEDE
ERILFRYFGENPNGSLQAIAGITSKNFKVAGMMPHPERAMNPVIGEVDGKIVLDLILSA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321498, Length=237, Percent_Identity=32.9113924050633, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582111, Length=234, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24582109, Length=234, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17137292, Length=234, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24194; Mature: 24194

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIVTFPGSNCDSDIFRVLRDQYEAEVDRVWHRDQLDKKYELVILPGGFSYGDYLRSG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHC
AMAGFSPVMKSVKEHVNKGGKLFGICNGFQILTEAEFLPGALTRNKTLKYICKTVILKKG
CCCCHHHHHHHHHHHHCCCCCEEEEECCEEEEHHCCCCCCCCCCCHHHHHHHHHHHHCCC
SSGNPVTASLDSRKELKIPIAHADGCYYATSDVIKQLEDEERILFRYFGENPNGSLQAIA
CCCCCEEEECCCCCEEEEEEEECCCCEEHHHHHHHHHCCHHHEEEEEECCCCCCCEEEEE
GITSKNFKVAGMMPHPERAMNPVIGEVDGKIVLDLILSA
ECCCCCEEEEECCCCCHHHCCCCCCCCCCCEEEHEECCC
>Mature Secondary Structure
MKVAIVTFPGSNCDSDIFRVLRDQYEAEVDRVWHRDQLDKKYELVILPGGFSYGDYLRSG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHC
AMAGFSPVMKSVKEHVNKGGKLFGICNGFQILTEAEFLPGALTRNKTLKYICKTVILKKG
CCCCHHHHHHHHHHHHCCCCCEEEEECCEEEEHHCCCCCCCCCCCHHHHHHHHHHHHCCC
SSGNPVTASLDSRKELKIPIAHADGCYYATSDVIKQLEDEERILFRYFGENPNGSLQAIA
CCCCCEEEECCCCCEEEEEEEECCCCEEHHHHHHHHHCCHHHEEEEEECCCCCCCEEEEE
GITSKNFKVAGMMPHPERAMNPVIGEVDGKIVLDLILSA
ECCCCCEEEEECCCCCHHHCCCCCCCCCCCEEEHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA