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The map label for this gene is 116328947

Identifier: 116328947

GI number: 116328947

Start: 2780141

End: 2781184

Strand: Reverse

Name: 116328947

Synonym: LBL_2342

Alternate gene names: NA

Gene position: 2781184-2780141 (Counterclockwise)

Preceding gene: 116328957

Following gene: 116328945

Centisome position: 76.95

GC content: 43.3

Gene sequence:

>1044_bases
ATGAATAATTTCCTACTTTTCTTAACGATTGTTTTTCTTTTCCAAACTTGCTTTCCGATCGATCCGGAAAGAATCCGTTC
CCCCCATTTTCAAGACGGGAAGTATCACAATGTCGAAGAAGACGAAAGATTGAATAAGAGTTTTTTTTCGGTCCTTCGCT
GGAAAATTTTAGGTCCCGCGGATCCGCCTGCGGTGGAAGGAAACGTGGAAAAAATTCCGGAAGTGATTTCAAGAAAGAAA
GAGGATTTTCTCGCACCGCCAGGTAAGGTGAGAATCATCTGGCTCGGACACGCAACCGTATGGATTGCAACCAATTTTCA
CGGAAAGAGAACGCACATTATTACCGATCCGATTTTTACGGGAGTTCCTCCTTTTGTTAAACGACTTACGGAATTACCGA
TTCAACCGGAAAATCTTCCAGGAGTAGACATCGTATCGATCAGTCACGCACACAGAGACCATCTGGATATCGATTCCATC
AAAAAGATTCAGAAACTATTTCCGGAGGTTACCATTCACCTTCCTTCCGGAATGAGGGAATTTGCAAAAGATGAAGGTTT
TGAAAATACCGTTATCCAAGAATGGTGGACAGTTTCCGAATATGCCGGAACCAAGATACATTTTCTTCCCGCAAAACATT
GGAGTAGAATGGGGCTGACCGATATGAATCAATATCACTGGGGGAGTTACGCATTCGAATTTGAGAATATTAGAATATAC
TTTGGTGGAGACACCGGTTTCTCAAAACACTTTTCTGAAATCGGGGAACGATTCCCTCAGGGTTTTACTGCCACCCTACT
TCCGATCGGAGCTTTTAAGCCGAGATGGTTTATGGAACCTGCTCATATCGGACCGAAAGAGGCCTTGGAGGCGAGCGCTA
TCCTTCGTTCTTCCCTCTTTCTTCCGATTCATTGGGGAACTTTTACCCTTGGAGACGATCGTCCGTTCGAAGCGGCTCTT
TACCTGAAGAAATTACATTCTGAAAAAAAAGATTCGATTATTCCACTTAAAATTTGGGCTGTAGGTGAAATCGTCGATTT
GTAG

Upstream 100 bases:

>100_bases
GTTTCGGATCGGTTTTAAATCTTTTCGGAAGAAGTTCGTAGAACTTCTAAAAACTTCGAAATTTGGTGAAAGTTCGGGAT
GGAACGATTGATTTAACTTT

Downstream 100 bases:

>100_bases
AATTTTGTGTCTTAAATTTAAACGAGGTTCGTATTTTATAGAGTCTCGCCCATCATAACTAAGAACTTGTCCCAAAACTG
TCTTCAGTCCTCTGAGTGTA

Product: Zn-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNNFLLFLTIVFLFQTCFPIDPERIRSPHFQDGKYHNVEEDERLNKSFFSVLRWKILGPADPPAVEGNVEKIPEVISRKK
EDFLAPPGKVRIIWLGHATVWIATNFHGKRTHIITDPIFTGVPPFVKRLTELPIQPENLPGVDIVSISHAHRDHLDIDSI
KKIQKLFPEVTIHLPSGMREFAKDEGFENTVIQEWWTVSEYAGTKIHFLPAKHWSRMGLTDMNQYHWGSYAFEFENIRIY
FGGDTGFSKHFSEIGERFPQGFTATLLPIGAFKPRWFMEPAHIGPKEALEASAILRSSLFLPIHWGTFTLGDDRPFEAAL
YLKKLHSEKKDSIIPLKIWAVGEIVDL

Sequences:

>Translated_347_residues
MNNFLLFLTIVFLFQTCFPIDPERIRSPHFQDGKYHNVEEDERLNKSFFSVLRWKILGPADPPAVEGNVEKIPEVISRKK
EDFLAPPGKVRIIWLGHATVWIATNFHGKRTHIITDPIFTGVPPFVKRLTELPIQPENLPGVDIVSISHAHRDHLDIDSI
KKIQKLFPEVTIHLPSGMREFAKDEGFENTVIQEWWTVSEYAGTKIHFLPAKHWSRMGLTDMNQYHWGSYAFEFENIRIY
FGGDTGFSKHFSEIGERFPQGFTATLLPIGAFKPRWFMEPAHIGPKEALEASAILRSSLFLPIHWGTFTLGDDRPFEAAL
YLKKLHSEKKDSIIPLKIWAVGEIVDL
>Mature_347_residues
MNNFLLFLTIVFLFQTCFPIDPERIRSPHFQDGKYHNVEEDERLNKSFFSVLRWKILGPADPPAVEGNVEKIPEVISRKK
EDFLAPPGKVRIIWLGHATVWIATNFHGKRTHIITDPIFTGVPPFVKRLTELPIQPENLPGVDIVSISHAHRDHLDIDSI
KKIQKLFPEVTIHLPSGMREFAKDEGFENTVIQEWWTVSEYAGTKIHFLPAKHWSRMGLTDMNQYHWGSYAFEFENIRIY
FGGDTGFSKHFSEIGERFPQGFTATLLPIGAFKPRWFMEPAHIGPKEALEASAILRSSLFLPIHWGTFTLGDDRPFEAAL
YLKKLHSEKKDSIIPLKIWAVGEIVDL

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=327, Percent_Identity=31.4984709480122, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI170932481, Length=327, Percent_Identity=31.4984709480122, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17543104, Length=267, Percent_Identity=36.3295880149813, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI25148824, Length=255, Percent_Identity=35.6862745098039, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17543102, Length=255, Percent_Identity=35.6862745098039, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17543100, Length=255, Percent_Identity=35.6862745098039, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6325154, Length=244, Percent_Identity=34.4262295081967, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39895; Mature: 39895

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFLLFLTIVFLFQTCFPIDPERIRSPHFQDGKYHNVEEDERLNKSFFSVLRWKILGPA
CCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
DPPAVEGNVEKIPEVISRKKEDFLAPPGKVRIIWLGHATVWIATNFHGKRTHIITDPIFT
CCCCCCCCHHHHHHHHHCCHHHHCCCCCCEEEEEEECEEEEEEECCCCCEEEEEECHHHC
GVPPFVKRLTELPIQPENLPGVDIVSISHAHRDHLDIDSIKKIQKLFPEVTIHLPSGMRE
CCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHH
FAKDEGFENTVIQEWWTVSEYAGTKIHFLPAKHWSRMGLTDMNQYHWGSYAFEFENIRIY
HHHCCCCCHHHHHHHHHHHHHCCCEEEEEECHHHHHCCCCCCCCCCCCCEEEEECCEEEE
FGGDTGFSKHFSEIGERFPQGFTATLLPIGAFKPRWFMEPAHIGPKEALEASAILRSSLF
ECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCE
LPIHWGTFTLGDDRPFEAALYLKKLHSEKKDSIIPLKIWAVGEIVDL
EEEECCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCC
>Mature Secondary Structure
MNNFLLFLTIVFLFQTCFPIDPERIRSPHFQDGKYHNVEEDERLNKSFFSVLRWKILGPA
CCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
DPPAVEGNVEKIPEVISRKKEDFLAPPGKVRIIWLGHATVWIATNFHGKRTHIITDPIFT
CCCCCCCCHHHHHHHHHCCHHHHCCCCCCEEEEEEECEEEEEEECCCCCEEEEEECHHHC
GVPPFVKRLTELPIQPENLPGVDIVSISHAHRDHLDIDSIKKIQKLFPEVTIHLPSGMRE
CCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHH
FAKDEGFENTVIQEWWTVSEYAGTKIHFLPAKHWSRMGLTDMNQYHWGSYAFEFENIRIY
HHHCCCCCHHHHHHHHHHHHHCCCEEEEEECHHHHHCCCCCCCCCCCCCEEEEECCEEEE
FGGDTGFSKHFSEIGERFPQGFTATLLPIGAFKPRWFMEPAHIGPKEALEASAILRSSLF
ECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCE
LPIHWGTFTLGDDRPFEAALYLKKLHSEKKDSIIPLKIWAVGEIVDL
EEEECCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]