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The map label for this gene is ruvB [H]

Identifier: 116328923

GI number: 116328923

Start: 2741667

End: 2742692

Strand: Reverse

Name: ruvB [H]

Synonym: LBL_2317

Alternate gene names: 116328923

Gene position: 2742692-2741667 (Counterclockwise)

Preceding gene: 116328924

Following gene: 116328922

Centisome position: 75.88

GC content: 44.05

Gene sequence:

>1026_bases
TTGGCAAAATCCCATACGCTTAATCCTGAGGAAGAATTTGAAGAAGAGTCGGGTTTACGTCCTTCTCTTCTTTCCGAATT
TATAGGTCAGAAGGAAGTTCTCAATAATCTTACGGTTTACGTTCAGGCTGCTAAGAATCGAAAGCGTGCGCTTGATCACG
TTTTGATTTCCGGTCCTCCTGGTCTTGGTAAAACGACTCTTGCCGGAATTGTTTCCAACGAACTTGGGACCAGGCTTACC
ATTACATCTGCTCCTGTGATTACCAAAGGCGCCGATCTTGCCCGTCTTCTTACGAGTATGGGAGAAAATGAAATTCTATT
CATAGATGAAATCCATACTCTTCATAAAAAACTCGAAGAGATTCTCTATCCGGCGATGGAGAATTATATGATCGATCTAG
TGATTGGAGAAGGAGTAACCGCGCAAATGGTTCAAATTCCTCTCAAACCATTCACCTTAGTCGGGGCTACTACCAGAAGT
GGACTGATCAGCGAACCTCTCAAAAGCCGCTTCGGAATTCAATTGAGGCTGGATTATTACAACGATGAAGAGATGAAGGA
GATCGTTTTGCGTTCTTCTCGAATTTTGGGAGTTAAGATCGAAGACGATGCTGCCTTGGAAATCGGAAAACGTTCTCGTA
AAACTCCCCGAATTGCAAATCATCTTTTAAAGAGAATTCGGGACTTTAGCGAAGTAGAGGGTAATCTTTCCGTAAAAAAG
GGTCTTTGTCTCAAAGCGTTCGAAAAGATGGGGATTGACGACTTGGGATTGGACGGTATGGATCGACAGATACTGGGTTG
TATGATCGATCGTTATAAGGGAGGTCCTGTCGGTTTAAAGGCGATTGCTGTCGTAGTCGGAGAAGAAGAGAAGACTATCG
AAGATACTTACGAATCATTTATGGTTCGGATCGGACTCATCAATCGAACTCCCGCCGGTAGGGTGGCGACCGAAAAGGCC
TATCGGCAATTGAAACGAATGCAAGATTTTTCCGAAAACCATGGACAAGACCCGACTCTATTCTGA

Upstream 100 bases:

>100_bases
GGTTAAGAAGAGTAAGGTGGGTGATCGTATCACGGTTACGGTTATGCGTCAGGGAAACGTTTCTAGAATTTCGATCCAGC
TTAAGGAAAGACCGAACTGA

Downstream 100 bases:

>100_bases
ATATTCCGGAATTCCCGAAGACGATCGAAGGTTGATCTATGCCTCCTTTCTAGTTCTTGTACTCGCGTCCTTTTTTACCG
CACATTTGCTCACACGTAAC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPPGLGKTTLAGIVSNELGTRLT
ITSAPVITKGADLARLLTSMGENEILFIDEIHTLHKKLEEILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRS
GLISEPLKSRFGIQLRLDYYNDEEMKEIVLRSSRILGVKIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKK
GLCLKAFEKMGIDDLGLDGMDRQILGCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESFMVRIGLINRTPAGRVATEKA
YRQLKRMQDFSENHGQDPTLF

Sequences:

>Translated_341_residues
MAKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPPGLGKTTLAGIVSNELGTRLT
ITSAPVITKGADLARLLTSMGENEILFIDEIHTLHKKLEEILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRS
GLISEPLKSRFGIQLRLDYYNDEEMKEIVLRSSRILGVKIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKK
GLCLKAFEKMGIDDLGLDGMDRQILGCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESFMVRIGLINRTPAGRVATEKA
YRQLKRMQDFSENHGQDPTLF
>Mature_340_residues
AKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPPGLGKTTLAGIVSNELGTRLTI
TSAPVITKGADLARLLTSMGENEILFIDEIHTLHKKLEEILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRSG
LISEPLKSRFGIQLRLDYYNDEEMKEIVLRSSRILGVKIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKKG
LCLKAFEKMGIDDLGLDGMDRQILGCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESFMVRIGLINRTPAGRVATEKAY
RQLKRMQDFSENHGQDPTLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=309, Percent_Identity=48.5436893203884, Blast_Score=330, Evalue=8e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37997; Mature: 37865

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPP
CCCCCCCCCHHHHHHHCCCCHHHHHHHHCHHHHHCCCEEEEEEHHHHHHHHHEEEEECCC
GLGKTTLAGIVSNELGTRLTITSAPVITKGADLARLLTSMGENEILFIDEIHTLHKKLEE
CCCHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
ILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRSGLISEPLKSRFGIQLRLDYY
HHHHHHHCEEEEEEECCCCCCHHHEECCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECC
NDEEMKEIVLRSSRILGVKIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKK
CCHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHC
GLCLKAFEKMGIDDLGLDGMDRQILGCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESF
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHH
MVRIGLINRTPAGRVATEKAYRQLKRMQDFSENHGQDPTLF
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPP
CCCCCCCCHHHHHHHCCCCHHHHHHHHCHHHHHCCCEEEEEEHHHHHHHHHEEEEECCC
GLGKTTLAGIVSNELGTRLTITSAPVITKGADLARLLTSMGENEILFIDEIHTLHKKLEE
CCCHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
ILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRSGLISEPLKSRFGIQLRLDYY
HHHHHHHCEEEEEEECCCCCCHHHEECCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECC
NDEEMKEIVLRSSRILGVKIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKK
CCHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHC
GLCLKAFEKMGIDDLGLDGMDRQILGCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESF
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHH
MVRIGLINRTPAGRVATEKAYRQLKRMQDFSENHGQDPTLF
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA