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The map label for this gene is prpC [H]

Identifier: 116328799

GI number: 116328799

Start: 2555519

End: 2556337

Strand: Reverse

Name: prpC [H]

Synonym: LBL_2174

Alternate gene names: 116328799

Gene position: 2556337-2555519 (Counterclockwise)

Preceding gene: 116328800

Following gene: 116328796

Centisome position: 70.73

GC content: 44.32

Gene sequence:

>819_bases
ATGATTATCAACTACTTTGGAATTACGGAAAAAGGAAATTTTCGTTCACATAACGAGGATTCGATGTACGTATCTGGAGA
AATTGTGGCCGGAAACGTTTCGGGTTCTTTTTCCTCTTCCGGAATTCGAGATTCCGCGGCGGCTCCTCTGATTTTCGCCC
TTGCGGACGGGATGGGTGGACATATCTCCGGAGAAGTCGCCAGTCGTATGACGCTTGAAAAACTCGCATGGACGGAAAGG
GCCGTTCAACCTTTGGAAGAATTGCCGCATGAGGGTTGGCAAAGTTTATTCAACATCATCAATCATGAAATCAATGATCA
CGCTAAGGCGACCGGAAAACTGGGAATGGGGGCTACGTTAGTCGGCATATTGTTCGGAAGGAAAAAAGTCCTCGTATTCA
ACATGGGAGACAGTAGGGCTTATCATTTTTCCTCCAAAGGGATCCATAAAATTACGGTCGATCATTCTTTTGCGGGTACT
ATCAAGGGAAACCAGATTTCTAGGAGTTATATCACGAGTTGTATCGGAGGAGGAACTACGGATCTTCAGATGGATCTTTT
CGACATCACGAGTTCGCTCAACAAAGGGGATCGAATTTTGCTTTGTACGGACGGGTTGACGGACGTCATCAAAATAGATG
ATTTGGAAGAGATCTTAAAAAACTCGTCTAACGTAAAAGAGGCCTGTTATCATCTTTTGGAGGAAGCGAACCTAAGAATG
ACGAAGGATAATACTTCTATAATCGTGATCGAAGTTCAGGGAACTATGTTTGCCCGTTCCGAACCTCGAAAACTTACCCC
AAGCGAAAAAAAACCGTAA

Upstream 100 bases:

>100_bases
AAAAAATCATTTAACGAAGATTTCTTCTTGAAGTTCCTTATTGATGACACATATTTATAATAAAGTTTTGGAAATTATTT
CAATTTAACAGTGTTTCTCC

Downstream 100 bases:

>100_bases
GAGTAAAGAAATAGTTTCCGTTCGGAGTTTTTTCGAAAGAGGAACGAAACGGAAAATCGGATTTTCTTAATATTTCCAAA
AACCCCAAACCGGCGCCTTT

Product: Serine/threonine specific protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MIINYFGITEKGNFRSHNEDSMYVSGEIVAGNVSGSFSSSGIRDSAAAPLIFALADGMGGHISGEVASRMTLEKLAWTER
AVQPLEELPHEGWQSLFNIINHEINDHAKATGKLGMGATLVGILFGRKKVLVFNMGDSRAYHFSSKGIHKITVDHSFAGT
IKGNQISRSYITSCIGGGTTDLQMDLFDITSSLNKGDRILLCTDGLTDVIKIDDLEEILKNSSNVKEACYHLLEEANLRM
TKDNTSIIVIEVQGTMFARSEPRKLTPSEKKP

Sequences:

>Translated_272_residues
MIINYFGITEKGNFRSHNEDSMYVSGEIVAGNVSGSFSSSGIRDSAAAPLIFALADGMGGHISGEVASRMTLEKLAWTER
AVQPLEELPHEGWQSLFNIINHEINDHAKATGKLGMGATLVGILFGRKKVLVFNMGDSRAYHFSSKGIHKITVDHSFAGT
IKGNQISRSYITSCIGGGTTDLQMDLFDITSSLNKGDRILLCTDGLTDVIKIDDLEEILKNSSNVKEACYHLLEEANLRM
TKDNTSIIVIEVQGTMFARSEPRKLTPSEKKP
>Mature_272_residues
MIINYFGITEKGNFRSHNEDSMYVSGEIVAGNVSGSFSSSGIRDSAAAPLIFALADGMGGHISGEVASRMTLEKLAWTER
AVQPLEELPHEGWQSLFNIINHEINDHAKATGKLGMGATLVGILFGRKKVLVFNMGDSRAYHFSSKGIHKITVDHSFAGT
IKGNQISRSYITSCIGGGTTDLQMDLFDITSSLNKGDRILLCTDGLTDVIKIDDLEEILKNSSNVKEACYHLLEEANLRM
TKDNTSIIVIEVQGTMFARSEPRKLTPSEKKP

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 29713; Mature: 29713

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINYFGITEKGNFRSHNEDSMYVSGEIVAGNVSGSFSSSGIRDSAAAPLIFALADGMGG
CEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCC
HISGEVASRMTLEKLAWTERAVQPLEELPHEGWQSLFNIINHEINDHAKATGKLGMGATL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHH
VGILFGRKKVLVFNMGDSRAYHFSSKGIHKITVDHSFAGTIKGNQISRSYITSCIGGGTT
HHHHHCCCEEEEEECCCCCEEEECCCCEEEEEECCCEEEEECCCCHHHHHHHHHHCCCCC
DLQMDLFDITSSLNKGDRILLCTDGLTDVIKIDDLEEILKNSSNVKEACYHLLEEANLRM
CEEEHHHHHHHHCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHCCCEE
TKDNTSIIVIEVQGTMFARSEPRKLTPSEKKP
EECCCEEEEEEECCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MIINYFGITEKGNFRSHNEDSMYVSGEIVAGNVSGSFSSSGIRDSAAAPLIFALADGMGG
CEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCC
HISGEVASRMTLEKLAWTERAVQPLEELPHEGWQSLFNIINHEINDHAKATGKLGMGATL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHH
VGILFGRKKVLVFNMGDSRAYHFSSKGIHKITVDHSFAGTIKGNQISRSYITSCIGGGTT
HHHHHCCCEEEEEECCCCCEEEECCCCEEEEEECCCEEEEECCCCHHHHHHHHHHCCCCC
DLQMDLFDITSSLNKGDRILLCTDGLTDVIKIDDLEEILKNSSNVKEACYHLLEEANLRM
CEEEHHHHHHHHCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHCCCEE
TKDNTSIIVIEVQGTMFARSEPRKLTPSEKKP
EECCCEEEEEEECCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]