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The map label for this gene is pkn2 [H]

Identifier: 116328796

GI number: 116328796

Start: 2551555

End: 2553027

Strand: Reverse

Name: pkn2 [H]

Synonym: LBL_2171

Alternate gene names: 116328796

Gene position: 2553027-2551555 (Counterclockwise)

Preceding gene: 116328799

Following gene: 116328789

Centisome position: 70.63

GC content: 42.77

Gene sequence:

>1473_bases
ATGTGGAATGAAACTCTTTTCGAACAAAAGAAAAAATCTTTGGAAGGATTCGGAGTTTTATCGAAAAAATCCATTGCTCG
ATTTATGGACAACATAAGGGTTCTGGACGAATGGCAGCTCCATCGGATTAATCCGATTCGTTTTGCAAAGCAGAATGATT
TTGAAATAGGAGAGACGCTCGATCTTTTCCTTCATTCCGCAAAGATCGGTTTTCTTGATTTTGCGTACAACATGATTTGC
CCCGCTTGTGGAGGTGTTGCCGCTTCTCACACTTCTTTGGATCAAATCGAGGAAAAAAGTTTTCATTGTTATATCTGTAA
CATAGACGTGCCGACTACTTTGGATGATCAGGTGGAAGTCAGCTTTTCGGCGAACCCGTCCCTTAAGAAACAATCCTTGA
ATCCTTTGGTGGATGTGGAAACGTATCTCAGATATCATATTTCCGCCAACTTTTGCAAGTCCAAAGAGCTTCTGAATTTC
ATTTTTTCGAATATTCAAGATTTAATCGTTATGGAACCGGGGGAGACAAAACGAATCCATTTGGATGCGACGAACGTTCC
CGTGTATCAATTCAGTTCTGTGGAAAATAATTCGGCCGTTTTTTTGTATTTTGATTCTAAGGAAGTCACGAAGGATCGGA
TCATCGACCTCAGTCTTCTTCCTACCGGATTTACTCCCGTTGAATTACATCTTTCACCGGGGGAGTACGAGGTGAAAGTT
TCCAACCGGACGATCGCAACCTCCGGCTTTTTAATCATTAAACCAAACTTGAAAAGAATCCTGGAAATTATCGGGGAACA
TCCGACGGTGATCCAACCGTTTCTGACCGCGAAGATGCTTTTGAACAATCAAACCTTCCGGGAATTATTCCGCGTTCAAC
GATTGAGCAGTCAATTGAATTTAAACGTAAAAAGTCTTACGATCCTTTTTACGGATTTGAGAGGCTCGACCGAAATATAC
GATAAAGCGGGGGATATCCTTGCATATCGATTGGTTCAGGAACATTTCCGTTTGCTCGCCGAAACCGTAAAGAAGTTTAA
CGGCGCCATCGTAAAAACGATGGGAGACGCGGTTATGGCGACCTTTTCTAGTCCGCTGGAAGGACTATTTGCTTCATTAG
AAATGATGTTTCGTATCGATCGGATGAACGAGGAATTTAAGGAACACGGACATGAGATCGGTTTGAAGGTCGGTTTAAAT
GAAGGTTCTGCTCTTGCCGTTATCAACGACGAAAGACTTGATTACTTCGGTCAGAGCGTAAATATTGCGGCAAGAGTGCA
AGCGCTTGCATCTGCGGGAGAAATCTGGGTGACTGAGCCGATTCTTTCCAGTCCTGGAATTCAGGAAGAATTAAATCTGA
AAGGATATGGATCCGAAAGATATGAGGCTTTTTTGAAAGGAGTCGGTCAAAAAGCCGCCGTTCACAAACTGTTTAAGAAC
GAGGAACAAAGGGCGTTTGTAGGGTCGGTTTAA

Upstream 100 bases:

>100_bases
GTTTTAAATAAGTGTAATAAAAAAAGTTACGAAATGCTTGACGAGTAATGGACATTCGGGAAACTGGGTCCGTTTTGAAT
TAAGAATCCGGGAGAACGTT

Downstream 100 bases:

>100_bases
ATTTTCGAAATAAATTCAAGAATTTGAATGTGTTTCATTAGAGAATTCGAGCCCGAGTTTATTTTTAAATTTCTATGTCA
GTGAAATCAAAATGATCGAT

Product: adenylate cyclase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MWNETLFEQKKKSLEGFGVLSKKSIARFMDNIRVLDEWQLHRINPIRFAKQNDFEIGETLDLFLHSAKIGFLDFAYNMIC
PACGGVAASHTSLDQIEEKSFHCYICNIDVPTTLDDQVEVSFSANPSLKKQSLNPLVDVETYLRYHISANFCKSKELLNF
IFSNIQDLIVMEPGETKRIHLDATNVPVYQFSSVENNSAVFLYFDSKEVTKDRIIDLSLLPTGFTPVELHLSPGEYEVKV
SNRTIATSGFLIIKPNLKRILEIIGEHPTVIQPFLTAKMLLNNQTFRELFRVQRLSSQLNLNVKSLTILFTDLRGSTEIY
DKAGDILAYRLVQEHFRLLAETVKKFNGAIVKTMGDAVMATFSSPLEGLFASLEMMFRIDRMNEEFKEHGHEIGLKVGLN
EGSALAVINDERLDYFGQSVNIAARVQALASAGEIWVTEPILSSPGIQEELNLKGYGSERYEAFLKGVGQKAAVHKLFKN
EEQRAFVGSV

Sequences:

>Translated_490_residues
MWNETLFEQKKKSLEGFGVLSKKSIARFMDNIRVLDEWQLHRINPIRFAKQNDFEIGETLDLFLHSAKIGFLDFAYNMIC
PACGGVAASHTSLDQIEEKSFHCYICNIDVPTTLDDQVEVSFSANPSLKKQSLNPLVDVETYLRYHISANFCKSKELLNF
IFSNIQDLIVMEPGETKRIHLDATNVPVYQFSSVENNSAVFLYFDSKEVTKDRIIDLSLLPTGFTPVELHLSPGEYEVKV
SNRTIATSGFLIIKPNLKRILEIIGEHPTVIQPFLTAKMLLNNQTFRELFRVQRLSSQLNLNVKSLTILFTDLRGSTEIY
DKAGDILAYRLVQEHFRLLAETVKKFNGAIVKTMGDAVMATFSSPLEGLFASLEMMFRIDRMNEEFKEHGHEIGLKVGLN
EGSALAVINDERLDYFGQSVNIAARVQALASAGEIWVTEPILSSPGIQEELNLKGYGSERYEAFLKGVGQKAAVHKLFKN
EEQRAFVGSV
>Mature_490_residues
MWNETLFEQKKKSLEGFGVLSKKSIARFMDNIRVLDEWQLHRINPIRFAKQNDFEIGETLDLFLHSAKIGFLDFAYNMIC
PACGGVAASHTSLDQIEEKSFHCYICNIDVPTTLDDQVEVSFSANPSLKKQSLNPLVDVETYLRYHISANFCKSKELLNF
IFSNIQDLIVMEPGETKRIHLDATNVPVYQFSSVENNSAVFLYFDSKEVTKDRIIDLSLLPTGFTPVELHLSPGEYEVKV
SNRTIATSGFLIIKPNLKRILEIIGEHPTVIQPFLTAKMLLNNQTFRELFRVQRLSSQLNLNVKSLTILFTDLRGSTEIY
DKAGDILAYRLVQEHFRLLAETVKKFNGAIVKTMGDAVMATFSSPLEGLFASLEMMFRIDRMNEEFKEHGHEIGLKVGLN
EGSALAVINDERLDYFGQSVNIAARVQALASAGEIWVTEPILSSPGIQEELNLKGYGSERYEAFLKGVGQKAAVHKLFKN
EEQRAFVGSV

Specific function: Regulates the activity of endogenous beta-lactamase or related enzymes, by blocking their secretion by phosphorylation, in response to an external signal yet to be identified [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271
- InterPro:   IPR002290 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 55326; Mature: 55326

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWNETLFEQKKKSLEGFGVLSKKSIARFMDNIRVLDEWQLHRINPIRFAKQNDFEIGETL
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCCCCCCEEECCCCCCCCCHHH
DLFLHSAKIGFLDFAYNMICPACGGVAASHTSLDQIEEKSFHCYICNIDVPTTLDDQVEV
HHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCEEEEEEEECCCCCCCCCEEE
SFSANPSLKKQSLNPLVDVETYLRYHISANFCKSKELLNFIFSNIQDLIVMEPGETKRIH
EECCCCCCHHHCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEE
LDATNVPVYQFSSVENNSAVFLYFDSKEVTKDRIIDLSLLPTGFTPVELHLSPGEYEVKV
EECCCCCEEEEECCCCCCEEEEEECCCCCCHHHEEEEEECCCCCCEEEEEECCCCEEEEE
SNRTIATSGFLIIKPNLKRILEIIGEHPTVIQPFLTAKMLLNNQTFRELFRVQRLSSQLN
CCEEEEECCEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
LNVKSLTILFTDLRGSTEIYDKAGDILAYRLVQEHFRLLAETVKKFNGAIVKTMGDAVMA
CCEEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHH
TFSSPLEGLFASLEMMFRIDRMNEEFKEHGHEIGLKVGLNEGSALAVINDERLDYFGQSV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCHHHHCCCCC
NIAARVQALASAGEIWVTEPILSSPGIQEELNLKGYGSERYEAFLKGVGQKAAVHKLFKN
CHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHCC
EEQRAFVGSV
CCCCHHCCCC
>Mature Secondary Structure
MWNETLFEQKKKSLEGFGVLSKKSIARFMDNIRVLDEWQLHRINPIRFAKQNDFEIGETL
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCCCCCCEEECCCCCCCCCHHH
DLFLHSAKIGFLDFAYNMICPACGGVAASHTSLDQIEEKSFHCYICNIDVPTTLDDQVEV
HHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCEEEEEEEECCCCCCCCCEEE
SFSANPSLKKQSLNPLVDVETYLRYHISANFCKSKELLNFIFSNIQDLIVMEPGETKRIH
EECCCCCCHHHCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEE
LDATNVPVYQFSSVENNSAVFLYFDSKEVTKDRIIDLSLLPTGFTPVELHLSPGEYEVKV
EECCCCCEEEEECCCCCCEEEEEECCCCCCHHHEEEEEECCCCCCEEEEEECCCCEEEEE
SNRTIATSGFLIIKPNLKRILEIIGEHPTVIQPFLTAKMLLNNQTFRELFRVQRLSSQLN
CCEEEEECCEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
LNVKSLTILFTDLRGSTEIYDKAGDILAYRLVQEHFRLLAETVKKFNGAIVKTMGDAVMA
CCEEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHH
TFSSPLEGLFASLEMMFRIDRMNEEFKEHGHEIGLKVGLNEGSALAVINDERLDYFGQSV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCHHHHCCCCC
NIAARVQALASAGEIWVTEPILSSPGIQEELNLKGYGSERYEAFLKGVGQKAAVHKLFKN
CHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHCC
EEQRAFVGSV
CCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7774814 [H]