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The map label for this gene is infC

Identifier: 116328739

GI number: 116328739

Start: 2470852

End: 2471391

Strand: Reverse

Name: infC

Synonym: LBL_2113

Alternate gene names: 116328739

Gene position: 2471391-2470852 (Counterclockwise)

Preceding gene: 116328741

Following gene: 116328738

Centisome position: 68.38

GC content: 39.44

Gene sequence:

>540_bases
ATGCAGAGGAAACCGAGTCAAAAATCAGCAACGGATAAGCTTTTTAATCATAGGATCAATGAGAAAATTACAGGCGTTTC
CAGGGTTCGTTTAGTGTCGGATGATGGAGTGGCGATCGTATCTTTTGAAGAAGCCCTCAGAAAAGCAAAAGAAGAGAACT
TGGATCTCGTTGAAGTATCGGCGGATCAGGAGTTACACGTTTGTAAGATCATCGACTATGGGAAATATAAATTCGAGCTA
CTTAAAAAGAATAAGGAAGCTAAGAAAAAACAACACGTAATCAATGTTAAAGAAATTAAGATTCGTCCTAGAATTGAAAG
CCACGATTACGAAATCAAAAAGAAACACGCACAGGAGTTTCTAGGAAAAGGCGATAAAGTCAAAGTAAGCCTCCGGTTCC
GCGGTAGAGAGATGATGCATTCCGACCTCGGTATGAAAGTCGTTTATAGAATGATCGAGGACCTGAAAGAATATGGATTG
GCGGAAAGAGATCCGATTCAAGATGGAAAACAGATCGTAGTAATCATTAATCCGAAATAA

Upstream 100 bases:

>100_bases
AAATCAACTTGAAATAAAGCCAGGTTCTGACGAAATAGCGTCAAAAATCGCTTGAAAACACACTTAAGGATAAAATCTTG
GAAATCTAGCCGGAGAATGA

Downstream 100 bases:

>100_bases
CATCCGGAAATAGGACCTAAAGGTAGATAAGATGCCCAAGTTGAAAACGAACAGAGCCGCTGCAAAGCGTTTTAAGTTCA
CAAAGAACAACAAAATCAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MQRKPSQKSATDKLFNHRINEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVSADQELHVCKIIDYGKYKFEL
LKKNKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEFLGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEYGL
AERDPIQDGKQIVVIINPK

Sequences:

>Translated_179_residues
MQRKPSQKSATDKLFNHRINEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVSADQELHVCKIIDYGKYKFEL
LKKNKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEFLGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEYGL
AERDPIQDGKQIVVIINPK
>Mature_179_residues
MQRKPSQKSATDKLFNHRINEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVSADQELHVCKIIDYGKYKFEL
LKKNKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEFLGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEYGL
AERDPIQDGKQIVVIINPK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=46.9879518072289, Blast_Score=130, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_LEPBJ (Q04U56)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_800322.1
- ProteinModelPortal:   Q04U56
- SMR:   Q04U56
- STRING:   Q04U56
- GeneID:   4409816
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_0920
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   LBOR355277:LBJ_0920-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20856; Mature: 20856

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRKPSQKSATDKLFNHRINEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVS
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEC
ADQELHVCKIIDYGKYKFELLKKNKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEF
CCCCEEEEEEEECCCHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
LGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEYGLAERDPIQDGKQIVVIINPK
HCCCCEEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MQRKPSQKSATDKLFNHRINEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVS
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEC
ADQELHVCKIIDYGKYKFELLKKNKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEF
CCCCEEEEEEEECCCHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
LGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEYGLAERDPIQDGKQIVVIINPK
HCCCCEEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA