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The map label for this gene is pqqL [C]

Identifier: 116328708

GI number: 116328708

Start: 2439328

End: 2440614

Strand: Reverse

Name: pqqL [C]

Synonym: LBL_2082

Alternate gene names: 116328708

Gene position: 2440614-2439328 (Counterclockwise)

Preceding gene: 116328709

Following gene: 116328706

Centisome position: 67.52

GC content: 40.95

Gene sequence:

>1287_bases
TTGGTACAGGAATCTTCACAGTTAGTTTATAGAAAAGTTCTACCCGGGGGAATTACTCTCCTTTTTCAACAAGCTCCTCA
TACAGTCAGTGCGTCTGCGGGAGTTTTTGTCCGTGTCGGTTCCAGACACGAATCTACTAAAAATGCCGGTTATTGTCATT
TTTTGGAGCACATGCTTTTCAAGGATACGGCTAAACGGACCGCTAAAGAACAAGCTGAAGACATAGAACGAGTCGGCGGT
TTTACTAACGCCGCTACTTCCAGAGAATACACCTACTTTCACGTAACGGTCGCCGGAAAACATATCGGCCTCGGCTTGGA
GCTGTTGGCCGAAATGATCTATGAACCCTTGCTCAAACAATCAGATATAGAAAACGAGGCAGGCGTGATTTTGGAGGAGC
TTCAAGGTTACGAGGATTCTCCGGAGGACTATATTCACGATTTCTACTATCAGAATTTTTTTCCTAAAAATTCTTTGGGA
CGAGACATCATTGGGACGAGAGAGTCCGTTTCAGGGGTTGATCACAGAAAATTATTAGAATTTTATAATACATATTATCA
TACGGAAAATATGTTTCTTTCGATTTCCGGAAACTTCGAACCGGACGAAATTTTTGCGATCGCCGGAAAGTATTTTAATA
AACTCAAAAAGAAAAAGAAAGATATAGATGCACTTCCCTTACCCAAAAAACAATGGGGTTACTTTCCGAAAAAGAAAAAA
CTGGAACAGGTTTATTTTGTTTTAGGTGGGGAGGGGTTTGCAAGAGAATTTCACAATGCCTCTTTGGCTAGCTTATTCAC
TCACATCTTAGGCGGTGGAACTTCTTCCAGACTTTTCCAAAAAGTTAGAGAAGAGAAAGGACTTTGTTATCAGATCACCG
CCTATCCTTCCTCTTATATAGACGTAGGTATCAATAGCATCGTTTGTTCCACTTCCAAGGAGAAATTCGTTACTTGTTTG
GAAACGATCGCCGACGAGATCAAATTGATTTTGGATCGTGGAATCACCGAAAGGGAACTTCTAGATGCCCAATCCAATCA
CGAAGGTGCTCTTTCGATCAGCTACGAACAAACCGAATCTCGTATGAATACGATTGCCCTCATGGAATTGTACTATGGCC
GTAATTATTCTTATGAAGAAAGGGTGAAAGAAATCTACTCGATCACTTTAGAGGATTTGAATCGTTTTGCAAGGTCGGCC
TTTGGGATTCCTAAGCTACATCTTTCGGCTCTCGGAAATTTGGGTTTAAAAGAAGAAAAGGCCGTTCAAAGGATTTTTTC
TTTTTAA

Upstream 100 bases:

>100_bases
TATCATTCGAGTAAAGGTTTTGAACGTGGATAAGACTGGAAAGATCGATCTTTCCAGAAAAGACGCTCTTGAGGAAATAT
AATATTTTTTTAATATTCCC

Downstream 100 bases:

>100_bases
AGTCATTAGAATAATCACTTTGTATATATATAAAGGAGTTTTATGAAGCGAATTTTCTGATGTTTGGACTTAGAGCCCGT
CTCAAAACCTTAGGAATGTA

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MVQESSQLVYRKVLPGGITLLFQQAPHTVSASAGVFVRVGSRHESTKNAGYCHFLEHMLFKDTAKRTAKEQAEDIERVGG
FTNAATSREYTYFHVTVAGKHIGLGLELLAEMIYEPLLKQSDIENEAGVILEELQGYEDSPEDYIHDFYYQNFFPKNSLG
RDIIGTRESVSGVDHRKLLEFYNTYYHTENMFLSISGNFEPDEIFAIAGKYFNKLKKKKKDIDALPLPKKQWGYFPKKKK
LEQVYFVLGGEGFAREFHNASLASLFTHILGGGTSSRLFQKVREEKGLCYQITAYPSSYIDVGINSIVCSTSKEKFVTCL
ETIADEIKLILDRGITERELLDAQSNHEGALSISYEQTESRMNTIALMELYYGRNYSYEERVKEIYSITLEDLNRFARSA
FGIPKLHLSALGNLGLKEEKAVQRIFSF

Sequences:

>Translated_428_residues
MVQESSQLVYRKVLPGGITLLFQQAPHTVSASAGVFVRVGSRHESTKNAGYCHFLEHMLFKDTAKRTAKEQAEDIERVGG
FTNAATSREYTYFHVTVAGKHIGLGLELLAEMIYEPLLKQSDIENEAGVILEELQGYEDSPEDYIHDFYYQNFFPKNSLG
RDIIGTRESVSGVDHRKLLEFYNTYYHTENMFLSISGNFEPDEIFAIAGKYFNKLKKKKKDIDALPLPKKQWGYFPKKKK
LEQVYFVLGGEGFAREFHNASLASLFTHILGGGTSSRLFQKVREEKGLCYQITAYPSSYIDVGINSIVCSTSKEKFVTCL
ETIADEIKLILDRGITERELLDAQSNHEGALSISYEQTESRMNTIALMELYYGRNYSYEERVKEIYSITLEDLNRFARSA
FGIPKLHLSALGNLGLKEEKAVQRIFSF
>Mature_428_residues
MVQESSQLVYRKVLPGGITLLFQQAPHTVSASAGVFVRVGSRHESTKNAGYCHFLEHMLFKDTAKRTAKEQAEDIERVGG
FTNAATSREYTYFHVTVAGKHIGLGLELLAEMIYEPLLKQSDIENEAGVILEELQGYEDSPEDYIHDFYYQNFFPKNSLG
RDIIGTRESVSGVDHRKLLEFYNTYYHTENMFLSISGNFEPDEIFAIAGKYFNKLKKKKKDIDALPLPKKQWGYFPKKKK
LEQVYFVLGGEGFAREFHNASLASLFTHILGGGTSSRLFQKVREEKGLCYQITAYPSSYIDVGINSIVCSTSKEKFVTCL
ETIADEIKLILDRGITERELLDAQSNHEGALSISYEQTESRMNTIALMELYYGRNYSYEERVKEIYSITLEDLNRFARSA
FGIPKLHLSALGNLGLKEEKAVQRIFSF

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=387, Percent_Identity=27.6485788113695, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI46593007, Length=214, Percent_Identity=28.9719626168224, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI24308013, Length=427, Percent_Identity=22.7166276346604, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI155969707, Length=255, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787770, Length=192, Percent_Identity=26.0416666666667, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71999683, Length=415, Percent_Identity=26.5060240963855, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17553678, Length=290, Percent_Identity=25.8620689655172, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323192, Length=416, Percent_Identity=25.7211538461538, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6321813, Length=413, Percent_Identity=22.7602905569007, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357875, Length=290, Percent_Identity=25.8620689655172, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646943, Length=290, Percent_Identity=25.8620689655172, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24641429, Length=224, Percent_Identity=27.2321428571429, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221513245, Length=336, Percent_Identity=23.2142857142857, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 48703; Mature: 48703

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQESSQLVYRKVLPGGITLLFQQAPHTVSASAGVFVRVGSRHESTKNAGYCHFLEHMLF
CCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
KDTAKRTAKEQAEDIERVGGFTNAATSREYTYFHVTVAGKHIGLGLELLAEMIYEPLLKQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHCCCHHHHHHHHHHHHHHH
SDIENEAGVILEELQGYEDSPEDYIHDFYYQNFFPKNSLGRDIIGTRESVSGVDHRKLLE
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHHH
FYNTYYHTENMFLSISGNFEPDEIFAIAGKYFNKLKKKKKDIDALPLPKKQWGYFPKKKK
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHH
LEQVYFVLGGEGFAREFHNASLASLFTHILGGGTSSRLFQKVREEKGLCYQITAYPSSYI
HHHEEEEECCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHH
DVGINSIVCSTSKEKFVTCLETIADEIKLILDRGITERELLDAQSNHEGALSISYEQTES
HHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEHHHHHH
RMNTIALMELYYGRNYSYEERVKEIYSITLEDLNRFARSAFGIPKLHLSALGNLGLKEEK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHH
AVQRIFSF
HHHHHHCC
>Mature Secondary Structure
MVQESSQLVYRKVLPGGITLLFQQAPHTVSASAGVFVRVGSRHESTKNAGYCHFLEHMLF
CCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
KDTAKRTAKEQAEDIERVGGFTNAATSREYTYFHVTVAGKHIGLGLELLAEMIYEPLLKQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHCCCHHHHHHHHHHHHHHH
SDIENEAGVILEELQGYEDSPEDYIHDFYYQNFFPKNSLGRDIIGTRESVSGVDHRKLLE
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHHH
FYNTYYHTENMFLSISGNFEPDEIFAIAGKYFNKLKKKKKDIDALPLPKKQWGYFPKKKK
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHH
LEQVYFVLGGEGFAREFHNASLASLFTHILGGGTSSRLFQKVREEKGLCYQITAYPSSYI
HHHEEEEECCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHH
DVGINSIVCSTSKEKFVTCLETIADEIKLILDRGITERELLDAQSNHEGALSISYEQTES
HHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEHHHHHH
RMNTIALMELYYGRNYSYEERVKEIYSITLEDLNRFARSAFGIPKLHLSALGNLGLKEEK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHH
AVQRIFSF
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]