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The map label for this gene is aphA [H]

Identifier: 116328668

GI number: 116328668

Start: 2376561

End: 2379158

Strand: Reverse

Name: aphA [H]

Synonym: LBL_2035

Alternate gene names: 116328668

Gene position: 2379158-2376561 (Counterclockwise)

Preceding gene: 116328671

Following gene: 116328667

Centisome position: 65.82

GC content: 41.15

Gene sequence:

>2598_bases
TTGTCGAACGAATGCATTCGTTTTTGGGGATTGAAAGGATTCAATCAGGAGCCGGATACGTTTCCTTCCTTTCTATTTCA
TCTTCATGGAAAAATTCGGAACTATGCGGATTTTACCGAAAAGATTCTTTTAAAACACATGCAAGATTTAGAATACTTCG
ATACACTTTTTACCGAAAGATACATTTTGCGTTTTTTTTGGAAAGCGGTCTTGAATAAAACGGAGTCGACGTATCGTATT
TATACATTCGAAATTTTGGCGCAGGAAGGGGACTGTGGGAATCTTTCTCCGGAAAGTCCTGGAGTGGAATCCATTTTTTA
CAAACTTCCGGAACCGGCGTTTTTATTCGATCCGTCCACTTTACGTTTTCTTGCCGTAAACGATGCCGCGATCCATCTCT
ATGGGTTTTCCAGAGAGGAATTTGCCGGTATGAATCTTTTGGAAATTCGTCCCGAGGAGGATCGCGCCGATATGGAAACC
GCGATCCAAAATGTCGCCAAGGAAACCGGAATTCGTTCCAGAGGAGTTTGGAGACATTGGAGGAAGGACAAAAAATTTCT
TTATGTAAAAATCACCACAAACCGAATTTCTCTTGGAGATTCTTTTGCGGTTTTGACGATTTTGACGAATGTTTCCGAGA
CGATAGAAACCTCTTATGCCTTAAGGCAAATTCGTGCGGAGAAACAATCCATCATCGAAAGTATGTCGGATCGATATTTT
GCGCTTTCCAAAGACTGGAGATTCATTTCTGCGAACCGGCAATCTCTTATTACATTAGGAAAGCCTAAAGAAGAATTGAT
AGGAAGGAATATCTGGGATTTGTATCCGGGAGCTTCGGTTCGATCCTTTCGGGACAAATTCGAACTTGCTGTCCGAACTC
GAAAGCCGATTACTTTCGAATATAAAATCATAGAAACCGGAAACGTGATGGAGTTTAGGGTTTTTCCTTTTGAGGAAGGG
GTCTCCGTGTTTTTTCAGGATATTACGGAAAAAAGGAAAAGAGATTCCGAACAGAACATTCTCAAAGAGATCGCTTTAAA
AATTCCGAAAGCGTCGAGCGTGAAAGAATCTTTCGAGATTCTTTTTGAGACGATTTGTAAGGGAACTTTTTGGAATTTTG
CCCAAACTTGGAGGTTTCAAAACGGTAAGATCGTTTTGGAGGAGAATTCGCCTTGGTACTCTACGGAAGCGACTTTCTTA
CGGTATAGAATCGCTTGTTTTGAAACCGGTTTTTCTCCCGGAGAGGGGTTGATCGGAGAGGTTTTTTCCACTCATAAAAT
TCGTTTTGTGAATGACGTTCAAAAGGAAAAAAATTTTAAAAGGACAGGTTTTGTGTTTCAAACCGGAATCCGGTCTTGGA
TTGCAATCCCTTTGCGAACCGGACATGAAACTTACGTTCTGGAGTTTTGTTCCCAGATTGAGTTGGATTCAGTAAATTCT
TATATTCAAATGTTTGAATTGATTTCGGATCAGATCGAAGTTTTGTTTAAAAACAAGGAATCGGAAGAGGAGAAGGATCA
TTTTTTTAAGTTGTCCGGAGACATGTTCCAGATTTCCACGTTGGACGGACAGATCATAGAACGTAACCATGCTTGGGAGG
AAGTTTTGGGGTATACTCGGGAGGAATTGAACGGAATCGATCTCGTTAAAATCGTTCATCCGAACGATCGGAACAAGATG
TTGAACACCCTCGTGAGTGTTCGAAAATACGGAAAAAATCTTTCGATCGCACTTCGATACGTAACCAAACACGGACGGAC
GAGGACGATTCTTTGGAAGACGATCGTTTCCCCGGAACACAGACTTGTTTACACCACGGGTAAGGATATCACCGAAATTC
AAAATACCCAGCTCCAACTTGAGAACATGGCGAAAGAACTGCAGCGTTCGAATTCGGATCTGGAAGATTTCGCTTTTATC
GCTTCTCACGACCTCCAGGAACCTTTGCGAAAGATTAAGGCGTTCGGAGATCGTCTTTTGAAAAGAAACTCAAATTTGGA
TTCGGAATCCGTGGATTATCTGCAAAGAATGTTTTTTTCCGCGCATCGATTATCCAACTTGATCGAAGGTCTTTTGTCTT
ATTCTCGGATTAAGAGTAGGGCGAAACCCTTTCAGCTCTTCGATTTAAGAAAAATTTTAAAAGATTCGATCGGCGATTTG
GAAATTTATATCAAGGAAAAAAATGCGAGAGTGGTCGATTCTGAAATCGGTTTTGCTTGGTGTGATCCGTTTCAAATGGG
GACGGTATTCCAGAATCTGATCAAAAACGGAATTAAATTCAATCAGAGCGAAAACCCCGAAGTGAACATTCGATGTATTC
CGCATCCTATCGAACCGAATTGGATTCAAATTACCTTTGCGGATAATGGAATCGGTTTTGACAAAAAGCACGACGGTAAG
ATATTTACGCTCTTTCAAAGGTTACACAGCCGGGAAGATTATGAAGGAAACGGAATCGGTCTTGCAGTTTGTAAAAAAAT
TATAGAATTTCACGGGGGAAGAATTTACGCCGAAAGCGTTTTACAGAAAGGTTCCACCTTTTATGTGGATCTTCCGGGCG
CTCTTACGTCTGTTCAAGAATATGAAAGCCGAAATTAA

Upstream 100 bases:

>100_bases
ACCCTTAGACATTCAATTTTTGGAAGAATTCTCTTCGGAGTTTGCTTCCTTTTAAGATCAGATCTGCATACTTGAAGAGT
GTTCTTCCGGAAAAATTCTC

Downstream 100 bases:

>100_bases
AAATCAAAGTTCGATTCATATACTCGTTGCGGAAGACGATCCGGACGATCGGCTATTGATGAGGGACGGTTTTCGGGAGA
ATAATCTGAACAATCCTCTA

Product: sensor histidine kinase of a two component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 864

Protein sequence:

>865_residues
MSNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTERYILRFFWKAVLNKTESTYRI
YTFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPSTLRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMET
AIQNVAKETGIRSRGVWRHWRKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYF
ALSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFEYKIIETGNVMEFRVFPFEEG
VSVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEILFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFL
RYRIACFETGFSPGEGLIGEVFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNS
YIQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTREELNGIDLVKIVHPNDRNKM
LNTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEHRLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFI
ASHDLQEPLRKIKAFGDRLLKRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDL
EIYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPNWIQITFADNGIGFDKKHDGK
IFTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESVLQKGSTFYVDLPGALTSVQEYESRN

Sequences:

>Translated_865_residues
MSNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTERYILRFFWKAVLNKTESTYRI
YTFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPSTLRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMET
AIQNVAKETGIRSRGVWRHWRKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYF
ALSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFEYKIIETGNVMEFRVFPFEEG
VSVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEILFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFL
RYRIACFETGFSPGEGLIGEVFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNS
YIQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTREELNGIDLVKIVHPNDRNKM
LNTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEHRLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFI
ASHDLQEPLRKIKAFGDRLLKRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDL
EIYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPNWIQITFADNGIGFDKKHDGK
IFTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESVLQKGSTFYVDLPGALTSVQEYESRN
>Mature_864_residues
SNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTERYILRFFWKAVLNKTESTYRIY
TFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPSTLRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMETA
IQNVAKETGIRSRGVWRHWRKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYFA
LSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFEYKIIETGNVMEFRVFPFEEGV
SVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEILFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFLR
YRIACFETGFSPGEGLIGEVFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNSY
IQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTREELNGIDLVKIVHPNDRNKML
NTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEHRLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFIA
SHDLQEPLRKIKAFGDRLLKRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDLE
IYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPNWIQITFADNGIGFDKKHDGKI
FTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESVLQKGSTFYVDLPGALTSVQEYESRN

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=354, Percent_Identity=25.1412429378531, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1789149, Length=251, Percent_Identity=27.8884462151394, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=23.7154150197628, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=274, Percent_Identity=24.0875912408759, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 100823; Mature: 100692

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTER
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YILRFFWKAVLNKTESTYRIYTFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPST
HHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEECCCC
LRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMETAIQNVAKETGIRSRGVWRHW
EEEEEECCCEEEEEECCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
RKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYF
CCCCEEEEEEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
ALSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFE
EECCCCEEEECCCCEEEECCCCHHHHHCCCHHHCCCCCHHHHHHHHHHHHEECCCCEEEE
YKIIETGNVMEFRVFPFEEGVSVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEI
EEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHH
LFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFLRYRIACFETGFSPGEGLIGE
HHHHHHCCCHHCCHHHEEECCCEEEEECCCCCCCCCHHHHHHEEHHHCCCCCCCCCHHHH
VFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNS
HHCCCCEEEHHHHHHHCCCCCCCHHHHHCCHHEEEEEEECCCHHHHHHHHHHCCHHHHHH
YIQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTR
HHHHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCEEEEEECCCHHHHCCCHHHHHHHHHH
EELNGIDLVKIVHPNDRNKMLNTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEH
HHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCEEEEEEEECCCCCC
RLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFIASHDLQEPLRKIKAFGDRLL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE
EIYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPN
EEEEEECCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
WIQITFADNGIGFDKKHDGKIFTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESV
EEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHH
LQKGSTFYVDLPGALTSVQEYESRN
HHCCCEEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure 
SNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTER
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YILRFFWKAVLNKTESTYRIYTFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPST
HHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEECCCC
LRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMETAIQNVAKETGIRSRGVWRHW
EEEEEECCCEEEEEECCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
RKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYF
CCCCEEEEEEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
ALSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFE
EECCCCEEEECCCCEEEECCCCHHHHHCCCHHHCCCCCHHHHHHHHHHHHEECCCCEEEE
YKIIETGNVMEFRVFPFEEGVSVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEI
EEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHH
LFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFLRYRIACFETGFSPGEGLIGE
HHHHHHCCCHHCCHHHEEECCCEEEEECCCCCCCCCHHHHHHEEHHHCCCCCCCCCHHHH
VFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNS
HHCCCCEEEHHHHHHHCCCCCCCHHHHHCCHHEEEEEEECCCHHHHHHHHHHCCHHHHHH
YIQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTR
HHHHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCEEEEEECCCHHHHCCCHHHHHHHHHH
EELNGIDLVKIVHPNDRNKMLNTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEH
HHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCEEEEEEEECCCCCC
RLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFIASHDLQEPLRKIKAFGDRLL
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE
EIYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPN
EEEEEECCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
WIQITFADNGIGFDKKHDGKIFTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESV
EEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHH
LQKGSTFYVDLPGALTSVQEYESRN
HHCCCEEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]