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The map label for this gene is ygcM [C]

Identifier: 116328595

GI number: 116328595

Start: 2280858

End: 2281268

Strand: Reverse

Name: ygcM [C]

Synonym: LBL_1952

Alternate gene names: 116328595

Gene position: 2281268-2280858 (Counterclockwise)

Preceding gene: 116328598

Following gene: 116328593

Centisome position: 63.12

GC content: 38.69

Gene sequence:

>411_bases
ATGTTTTTTGAAGAATCAGGAAGATTTTATATTCGAATCGAGGAACGTTTTGAATCCTCACATTTCCTCTACAAATATTT
TCCGGATGGTTCGGACGAACCTATACACGGACATTCTTGGAAAGTGGAACTCTATCTTTCCGGAAGAAAAAATATCGGCG
AGGACGGGATCAGTTTTGATTTTTTGACTTCCAAACAGAGACTTAAGGAACTCGTAGGAAAGTTGGATCATATTCTAATT
AACGAGTTGGAAGAATTTAAAAAGATCAATCCGACTTCCGAAAACATTGCGCGTTGGTTTTATCATTATCTTAAAGAAAG
TGTACATTCTGCCGGGGGAAGAGTGGATAAAATTGTCATTCACGAAGGCCCCGAAAATCTCGCCTTTTTCGAACCAACAT
CACTTCCGTAA

Upstream 100 bases:

>100_bases
CAAACTGCAAAAACACTAAGGTTCGTCTCGTAGGCTATAAAACCGTCTTAAATTTGCGGTTACTTCCAATATATAGACAT
GGGAAAGAAAGTCAAGAGCT

Downstream 100 bases:

>100_bases
GAAGTGATGTTGCGAAATCGCAGCGGTAGGGTAAGCGATTAGCTCACTGCGCAGGAGTGAAATCATCAACTCTTTTTACT
ATTATTCGGAGAGTTTATTA

Product: 6-pyruvoyl-tetrahydropterin synthase

Products: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; CMP

Alternate protein names: 6-Pyruvoyl Tetrahydrobiopterin Synthase; 6-Pyruvoyl-Tetrahydropterin Synthase; Queuosine Biosynthesis Protein QueD; 6-Pyruvoyl Tetrahydrobiopterin Synthase Family Protein; Preq(0) Biosynthesis Protein Qued; 6-Carboxy-5 6 7 8-Tetrahydropterin Synthase; 6-Pyruvoyltetrahydropterin Synthase; 6-Pyruvoyl Tetrahydrobiopterin Synthase-Like Protein; 6-Pyruvoyl Tetrahydropterin Synthase Superfamily; Queuosine Biosynthesis Protein

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MFFEESGRFYIRIEERFESSHFLYKYFPDGSDEPIHGHSWKVELYLSGRKNIGEDGISFDFLTSKQRLKELVGKLDHILI
NELEEFKKINPTSENIARWFYHYLKESVHSAGGRVDKIVIHEGPENLAFFEPTSLP

Sequences:

>Translated_136_residues
MFFEESGRFYIRIEERFESSHFLYKYFPDGSDEPIHGHSWKVELYLSGRKNIGEDGISFDFLTSKQRLKELVGKLDHILI
NELEEFKKINPTSENIARWFYHYLKESVHSAGGRVDKIVIHEGPENLAFFEPTSLP
>Mature_136_residues
MFFEESGRFYIRIEERFESSHFLYKYFPDGSDEPIHGHSWKVELYLSGRKNIGEDGISFDFLTSKQRLKELVGKLDHILI
NELEEFKKINPTSENIARWFYHYLKESVHSAGGRVDKIVIHEGPENLAFFEPTSLP

Specific function: Tetrahydrobiopterin biosynthesis; second step. [C]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.6.1.12

Molecular weight: Translated: 15999; Mature: 15999

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFEESGRFYIRIEERFESSHFLYKYFPDGSDEPIHGHSWKVELYLSGRKNIGEDGISFD
CCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEH
FLTSKQRLKELVGKLDHILINELEEFKKINPTSENIARWFYHYLKESVHSAGGRVDKIVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
HEGPENLAFFEPTSLP
ECCCCCCEEECCCCCC
>Mature Secondary Structure
MFFEESGRFYIRIEERFESSHFLYKYFPDGSDEPIHGHSWKVELYLSGRKNIGEDGISFD
CCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEH
FLTSKQRLKELVGKLDHILINELEEFKKINPTSENIARWFYHYLKESVHSAGGRVDKIVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
HEGPENLAFFEPTSLP
ECCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

Specific reaction: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA