The gene/protein map for NC_008508 is currently unavailable.
Definition Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence.
Accession NC_008508
Length 3,614,446

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The map label for this gene is phaB [H]

Identifier: 116328505

GI number: 116328505

Start: 2160796

End: 2161581

Strand: Reverse

Name: phaB [H]

Synonym: LBL_1854

Alternate gene names: 116328505

Gene position: 2161581-2160796 (Counterclockwise)

Preceding gene: 116328508

Following gene: 116328504

Centisome position: 59.8

GC content: 43.64

Gene sequence:

>786_bases
ATGACAAAAACGGCAATCATTACGGGTGGTACAGTCGGAATCGGCTATGAACTCAGTAAACTTATCGCGGCGGATGGTTA
CGATCTGATTCTCATAGCAAGAAACGAAAAAACTTTAAAAAAGGTAAAGAAGGAAATCGAATCGTCAAACAAGGTAAAGG
TGGAAACGCTTTCCGTCGATCTTGCGGATCCGAAGGCTTCTAAAAAGATCTTTGATTTCGCGAAAAAATCAAAAGCGGTT
GTGGAGATTCTTGTGAACAACGCGGGTTTTGGAACGAACGGAAGATTTGATCGAATGGATTTGCGGAAAGAACTGCAGAT
GATTCAAGTGAACGTGGCCTCCTTAGTCGAGTTGACACATCTATTTTTACAGGGTATGGTGGAACGGAAGAACGGAAAAA
TCCTGAACGTAGCGTCCACTGCGGCGTTTCAACCCGGGCCGAATATGGCGAATTATTATGCGACGAAGGCCTATGTGTTG
TCTTTTTCGGAAGCAGTCTACGAGGACGTTTATAAGGACGGAGTAACAATAACCGCTCTTTGCCCCGGACCCACGAAAAC
CGAATTTTTCGAAAGAACGGAGATAACCAAGTCGAAATTTTTGAACAATCCGATTGCTCCGATGATGAGTGCAAAAGAAG
TCGCCGAAATCGGATACGACGCTCTGAAAAAAGGAAAACCGGTCGTAATCTCGGGAACTTTAAACAAAATATTGGCCCAA
AGCGTAAGGATCGCACCCCGGTTTATTATCCGAAAGATCGCAAAGTTTCTAAATCAAAACAATTGA

Upstream 100 bases:

>100_bases
TTAAACAGTTAACACCGAACCGTCGTTTTCAATTCTTTCCAAAAAAAGTCTTTCTCTCTTTTTTCCCGAGATTAATTTCG
ACCGCAAGGGGAATCTATAA

Downstream 100 bases:

>100_bases
ACAAAAATGCAAGGATCGATTTTAGATTTAGCGGTTCCCTTTTTTCTGGTTTTAATCGGGTTAGAGATTTTTTATTCCCG
GACAGTCGGAAAGAAAGTGT

Product: Short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTKTAIITGGTVGIGYELSKLIAADGYDLILIARNEKTLKKVKKEIESSNKVKVETLSVDLADPKASKKIFDFAKKSKAV
VEILVNNAGFGTNGRFDRMDLRKELQMIQVNVASLVELTHLFLQGMVERKNGKILNVASTAAFQPGPNMANYYATKAYVL
SFSEAVYEDVYKDGVTITALCPGPTKTEFFERTEITKSKFLNNPIAPMMSAKEVAEIGYDALKKGKPVVISGTLNKILAQ
SVRIAPRFIIRKIAKFLNQNN

Sequences:

>Translated_261_residues
MTKTAIITGGTVGIGYELSKLIAADGYDLILIARNEKTLKKVKKEIESSNKVKVETLSVDLADPKASKKIFDFAKKSKAV
VEILVNNAGFGTNGRFDRMDLRKELQMIQVNVASLVELTHLFLQGMVERKNGKILNVASTAAFQPGPNMANYYATKAYVL
SFSEAVYEDVYKDGVTITALCPGPTKTEFFERTEITKSKFLNNPIAPMMSAKEVAEIGYDALKKGKPVVISGTLNKILAQ
SVRIAPRFIIRKIAKFLNQNN
>Mature_260_residues
TKTAIITGGTVGIGYELSKLIAADGYDLILIARNEKTLKKVKKEIESSNKVKVETLSVDLADPKASKKIFDFAKKSKAVV
EILVNNAGFGTNGRFDRMDLRKELQMIQVNVASLVELTHLFLQGMVERKNGKILNVASTAAFQPGPNMANYYATKAYVLS
FSEAVYEDVYKDGVTITALCPGPTKTEFFERTEITKSKFLNNPIAPMMSAKEVAEIGYDALKKGKPVVISGTLNKILAQS
VRIAPRFIIRKIAKFLNQNN

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=268, Percent_Identity=30.2238805970149, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI226371731, Length=203, Percent_Identity=33.0049261083744, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4557649, Length=207, Percent_Identity=32.8502415458937, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=28.1407035175879, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI20149619, Length=250, Percent_Identity=27.2, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=25.4098360655738, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4503817, Length=200, Percent_Identity=30.5, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40807363, Length=191, Percent_Identity=27.2251308900524, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=26.2626262626263, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32483357, Length=203, Percent_Identity=23.6453201970443, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680136, Length=186, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI44680133, Length=186, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI17738292, Length=186, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=26.2032085561497, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=28.7958115183246, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=29.5698924731183, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082160, Length=192, Percent_Identity=28.125, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786701, Length=207, Percent_Identity=25.1207729468599, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788459, Length=189, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789378, Length=220, Percent_Identity=28.6363636363636, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=225, Percent_Identity=31.5555555555556, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=208, Percent_Identity=31.25, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=258, Percent_Identity=25.5813953488372, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=196, Percent_Identity=29.0816326530612, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=28.0612244897959, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=231, Percent_Identity=28.1385281385281, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=192, Percent_Identity=25.5208333333333, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=237, Percent_Identity=27.8481012658228, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=195, Percent_Identity=31.2820512820513, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI212646214, Length=199, Percent_Identity=28.643216080402, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=27.0408163265306, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25152911, Length=190, Percent_Identity=28.4210526315789, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17557668, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=233, Percent_Identity=26.1802575107296, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559552, Length=193, Percent_Identity=26.4248704663212, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=193, Percent_Identity=26.4248704663212, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=221, Percent_Identity=25.7918552036199, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=188, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=260, Percent_Identity=27.3076923076923, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=185, Percent_Identity=34.0540540540541, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28574402, Length=185, Percent_Identity=34.0540540540541, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24640442, Length=190, Percent_Identity=33.1578947368421, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=31.1827956989247, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=31.1827956989247, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24584752, Length=181, Percent_Identity=33.7016574585635, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24639444, Length=220, Percent_Identity=28.1818181818182, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI116007236, Length=221, Percent_Identity=25.3393665158371, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=204, Percent_Identity=28.921568627451, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357041, Length=199, Percent_Identity=27.1356783919598, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641232, Length=213, Percent_Identity=24.8826291079812, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI23397609, Length=223, Percent_Identity=25.5605381165919, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355319, Length=222, Percent_Identity=24.7747747747748, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=27.4611398963731, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644339, Length=204, Percent_Identity=27.9411764705882, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=25.8064516129032, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24580925, Length=200, Percent_Identity=26, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24665247, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331216, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=22.9591836734694, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665243, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221331218, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 28760; Mature: 28629

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTKTAIITGGTVGIGYELSKLIAADGYDLILIARNEKTLKKVKKEIESSNKVKVETLSVD
CCCEEEEECCCEECCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEEEEE
LADPKASKKIFDFAKKSKAVVEILVNNAGFGTNGRFDRMDLRKELQMIQVNVASLVELTH
ECCCHHHHHHHHHHHHHHHEEHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LFLQGMVERKNGKILNVASTAAFQPGPNMANYYATKAYVLSFSEAVYEDVYKDGVTITAL
HHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
CPGPTKTEFFERTEITKSKFLNNPIAPMMSAKEVAEIGYDALKKGKPVVISGTLNKILAQ
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHCCCCEEEECHHHHHHHH
SVRIAPRFIIRKIAKFLNQNN
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKTAIITGGTVGIGYELSKLIAADGYDLILIARNEKTLKKVKKEIESSNKVKVETLSVD
CCEEEEECCCEECCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEEEEE
LADPKASKKIFDFAKKSKAVVEILVNNAGFGTNGRFDRMDLRKELQMIQVNVASLVELTH
ECCCHHHHHHHHHHHHHHHEEHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LFLQGMVERKNGKILNVASTAAFQPGPNMANYYATKAYVLSFSEAVYEDVYKDGVTITAL
HHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
CPGPTKTEFFERTEITKSKFLNNPIAPMMSAKEVAEIGYDALKKGKPVVISGTLNKILAQ
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHCCCCEEEECHHHHHHHH
SVRIAPRFIIRKIAKFLNQNN
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8566717 [H]