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The map label for this gene is purN [H]

Identifier: 116328231

GI number: 116328231

Start: 1818673

End: 1819299

Strand: Reverse

Name: purN [H]

Synonym: LBL_1555

Alternate gene names: 116328231

Gene position: 1819299-1818673 (Counterclockwise)

Preceding gene: 116328235

Following gene: 116328230

Centisome position: 50.33

GC content: 41.95

Gene sequence:

>627_bases
TTGGCAAGCCCGTTTACAAAGCCTAAAAAAAAGATCGTATTCTTAACTTCCGGAAGAGGTTCCAATCTCAAGGCAGTTCT
CCAAAGAATTAAAGTCGGAAAAATTCGGGGAGTTGGATCTGCATTGATTTGTGACAATCCGGATGCAAAAGCGCTGGAAG
TTGCTCAGGAATTTAAACTCCCTTCTCATGTTTTTAATTTTGCTTCCTTTGTGGACAAATCCGAATATCATAAGAAACTT
TTGAATTTCCTCATCGAGCTGGAACCCGACCTTATCGTAACCGCAGGTTATATGAAAATCCTGAAAAACCAGGTCATCCA
AGCTTTTCCCAATCGTATCATCAATATCCACCCTTCTCTTTTACCGGCATTTCCAGGACTGAATGCCCAAAAACAGGCCT
TTGAATACGGAGTTAAAATTGCCGGTTGCACTGCACATTTCGTGGACGAGGGAGTGGACTCCGGTCCCGTAATTCTTCAA
GGAGTCGTGAAAATCGAAGAAGGAATGTCGGAAAGAGATTTGACTCTGGAGATTCTCAAAGAGGAACATAAAATCCTACC
ACTCGCGGTTCAATACTTTTGCGAGGATAGGCTTAAGATCCATAATAGAAAGGTAAGCATTGAGTAA

Upstream 100 bases:

>100_bases
TTGACCGAGTTAGAAAAATCCGCTTGGTGTTCCCGAAATCGTCTTTCTGAATCAATTTCCAGTTCGGGGGCGATTCTGAT
TTTACCCGGATAAAATTTTC

Downstream 100 bases:

>100_bases
GTAATGATACAAATTAAGAGAGCTCTTATTTCCGTTAGCGACAAATCCGATATAGTAGAATTTGCACAATTTCTAAATCA
AAACGGCGTTGAAATCATCT

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MASPFTKPKKKIVFLTSGRGSNLKAVLQRIKVGKIRGVGSALICDNPDAKALEVAQEFKLPSHVFNFASFVDKSEYHKKL
LNFLIELEPDLIVTAGYMKILKNQVIQAFPNRIINIHPSLLPAFPGLNAQKQAFEYGVKIAGCTAHFVDEGVDSGPVILQ
GVVKIEEGMSERDLTLEILKEEHKILPLAVQYFCEDRLKIHNRKVSIE

Sequences:

>Translated_208_residues
MASPFTKPKKKIVFLTSGRGSNLKAVLQRIKVGKIRGVGSALICDNPDAKALEVAQEFKLPSHVFNFASFVDKSEYHKKL
LNFLIELEPDLIVTAGYMKILKNQVIQAFPNRIINIHPSLLPAFPGLNAQKQAFEYGVKIAGCTAHFVDEGVDSGPVILQ
GVVKIEEGMSERDLTLEILKEEHKILPLAVQYFCEDRLKIHNRKVSIE
>Mature_207_residues
ASPFTKPKKKIVFLTSGRGSNLKAVLQRIKVGKIRGVGSALICDNPDAKALEVAQEFKLPSHVFNFASFVDKSEYHKKLL
NFLIELEPDLIVTAGYMKILKNQVIQAFPNRIINIHPSLLPAFPGLNAQKQAFEYGVKIAGCTAHFVDEGVDSGPVILQG
VVKIEEGMSERDLTLEILKEEHKILPLAVQYFCEDRLKIHNRKVSIE

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=196, Percent_Identity=34.1836734693878, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI209869995, Length=196, Percent_Identity=34.1836734693878, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI209869993, Length=196, Percent_Identity=34.1836734693878, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI1788846, Length=198, Percent_Identity=37.8787878787879, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1787483, Length=199, Percent_Identity=29.1457286432161, Blast_Score=107, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17567511, Length=188, Percent_Identity=35.1063829787234, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24582400, Length=188, Percent_Identity=38.2978723404255, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 23209; Mature: 23077

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPFTKPKKKIVFLTSGRGSNLKAVLQRIKVGKIRGVGSALICDNPDAKALEVAQEFKL
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCC
PSHVFNFASFVDKSEYHKKLLNFLIELEPDLIVTAGYMKILKNQVIQAFPNRIINIHPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCHHEEEECCHH
LPAFPGLNAQKQAFEYGVKIAGCTAHFVDEGVDSGPVILQGVVKIEEGMSERDLTLEILK
HCCCCCCCHHHHHHHHCCEEECHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
EEHKILPLAVQYFCEDRLKIHNRKVSIE
HHHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure 
ASPFTKPKKKIVFLTSGRGSNLKAVLQRIKVGKIRGVGSALICDNPDAKALEVAQEFKL
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCC
PSHVFNFASFVDKSEYHKKLLNFLIELEPDLIVTAGYMKILKNQVIQAFPNRIINIHPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCHHEEEECCHH
LPAFPGLNAQKQAFEYGVKIAGCTAHFVDEGVDSGPVILQGVVKIEEGMSERDLTLEILK
HCCCCCCCHHHHHHHHCCEEECHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
EEHKILPLAVQYFCEDRLKIHNRKVSIE
HHHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]