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The map label for this gene is cysQ [H]

Identifier: 116328209

GI number: 116328209

Start: 1793228

End: 1794073

Strand: Direct

Name: cysQ [H]

Synonym: LBL_1533

Alternate gene names: 116328209

Gene position: 1793228-1794073 (Clockwise)

Preceding gene: 116328208

Following gene: 116328210

Centisome position: 49.61

GC content: 42.67

Gene sequence:

>846_bases
TTGGATTCGATTCAGTATCTTCAGCCCGCCGTAAACTCCGTTTTGGAAGCGGGCAAAATCGTATTAGAGATCTATAATTC
GGATTTTAAGGTTAAAGATAAGGGAAAAAACGATCCCGTCACCGAGGCAGATCTAAAAGCCGGGGCTCATATTTCCAGAA
ATTTACATTTTTTGAATATTCCGATTCTTTCCGAAGAAGATTCGGAAAAAAAGGATATCTCCAAATTTGTCGCGGCTTGG
ATTTTGGATCCGATCGACGGAACCCGCGAATTCGTGCATAAAAATCCAGAATTTGCGATCAGTTTAGGACTTTCCGTCAG
AGGCAAGGCGATCCTCGGAATCATTTTCAATCCAGTTACCCGCGAATTGATCTATGGAATGGAAAACTTAGGCATCGTTT
ATCAAAAGTTGGAAGAAATTCCAAATTCGTTCTCTATTGAATCCAGGAATTTTACGAAAACATTAAACAATTCTAAACCT
ACAAACAAAGTTCTCATTTCTAGAACCGAAGAAAAAGAAGGACTTTTCTTTTCCTCTATGATTCCTGTCGGTTGGGAGTT
TTCATCGATGGGTTCGATCGCATATAAGCTTGGTTTGGTAGCGGCGGGAAAAGCGTCTCTTTCGATTTCTCTAAAGCCCA
AAAATGATTGGGATATCTGCGCGGGAATCGCCCTTGTAAATGCCTCGGGAGGTTCCGACTTGGAAATTCGATCCGGCAAA
CCTTATAAGTTTCAAACGGTGGGCGGAAGAGGGGATGGACTTGTGGCGGGACATACCCCGTCTCTCATACAGGTCTGGGA
AAGTTCGAAATCGCATTTTCAATCGGGCCTAAAAGACTGGGATTAA

Upstream 100 bases:

>100_bases
CCAAACTCCTGAAAACGAAGTGTTTTATCTTCGTCCCGAAAATTTAGACGACCCTCATAAGGAAAATACCGCTAATCCGG
GCGGAAAGTAATTCTCTTTT

Downstream 100 bases:

>100_bases
TTTTTTTAGTAGAATCATGAAAAAAAAAGAATATTCTAAAAATATAATTCATACGATTAAAATCGGTGTAGATGCCAGAC
CTTTCTCCACTCCTGTTTCC

Product: inositol monophosphatase family protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MDSIQYLQPAVNSVLEAGKIVLEIYNSDFKVKDKGKNDPVTEADLKAGAHISRNLHFLNIPILSEEDSEKKDISKFVAAW
ILDPIDGTREFVHKNPEFAISLGLSVRGKAILGIIFNPVTRELIYGMENLGIVYQKLEEIPNSFSIESRNFTKTLNNSKP
TNKVLISRTEEKEGLFFSSMIPVGWEFSSMGSIAYKLGLVAAGKASLSISLKPKNDWDICAGIALVNASGGSDLEIRSGK
PYKFQTVGGRGDGLVAGHTPSLIQVWESSKSHFQSGLKDWD

Sequences:

>Translated_281_residues
MDSIQYLQPAVNSVLEAGKIVLEIYNSDFKVKDKGKNDPVTEADLKAGAHISRNLHFLNIPILSEEDSEKKDISKFVAAW
ILDPIDGTREFVHKNPEFAISLGLSVRGKAILGIIFNPVTRELIYGMENLGIVYQKLEEIPNSFSIESRNFTKTLNNSKP
TNKVLISRTEEKEGLFFSSMIPVGWEFSSMGSIAYKLGLVAAGKASLSISLKPKNDWDICAGIALVNASGGSDLEIRSGK
PYKFQTVGGRGDGLVAGHTPSLIQVWESSKSHFQSGLKDWD
>Mature_281_residues
MDSIQYLQPAVNSVLEAGKIVLEIYNSDFKVKDKGKNDPVTEADLKAGAHISRNLHFLNIPILSEEDSEKKDISKFVAAW
ILDPIDGTREFVHKNPEFAISLGLSVRGKAILGIIFNPVTRELIYGMENLGIVYQKLEEIPNSFSIESRNFTKTLNNSKP
TNKVLISRTEEKEGLFFSSMIPVGWEFSSMGSIAYKLGLVAAGKASLSISLKPKNDWDICAGIALVNASGGSDLEIRSGK
PYKFQTVGGRGDGLVAGHTPSLIQVWESSKSHFQSGLKDWD

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=207, Percent_Identity=31.8840579710145, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788882, Length=254, Percent_Identity=26.3779527559055, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320493, Length=249, Percent_Identity=26.5060240963855, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357329, Length=274, Percent_Identity=27.7372262773723, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664926, Length=239, Percent_Identity=28.4518828451883, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30863; Mature: 30863

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSIQYLQPAVNSVLEAGKIVLEIYNSDFKVKDKGKNDPVTEADLKAGAHISRNLHFLNI
CCCHHHHHHHHHHHHHHCEEEEEEECCCEEEECCCCCCCCCHHHHHCCCCHHCCEEEEEE
PILSEEDSEKKDISKFVAAWILDPIDGTREFVHKNPEFAISLGLSVRGKAILGIIFNPVT
EEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEECCEECCCEEEEEECCHHH
RELIYGMENLGIVYQKLEEIPNSFSIESRNFTKTLNNSKPTNKVLISRTEEKEGLFFSSM
HHHHHCHHHHHHHHHHHHHCCCCCEECCCCHHHHCCCCCCCCEEEEEECCCCCCEEEEEC
IPVGWEFSSMGSIAYKLGLVAAGKASLSISLKPKNDWDICAGIALVNASGGSDLEIRSGK
CCCCCCHHHHCHHHHHHHEEEECCCEEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCC
PYKFQTVGGRGDGLVAGHTPSLIQVWESSKSHFQSGLKDWD
CEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDSIQYLQPAVNSVLEAGKIVLEIYNSDFKVKDKGKNDPVTEADLKAGAHISRNLHFLNI
CCCHHHHHHHHHHHHHHCEEEEEEECCCEEEECCCCCCCCCHHHHHCCCCHHCCEEEEEE
PILSEEDSEKKDISKFVAAWILDPIDGTREFVHKNPEFAISLGLSVRGKAILGIIFNPVT
EEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEECCEECCCEEEEEECCHHH
RELIYGMENLGIVYQKLEEIPNSFSIESRNFTKTLNNSKPTNKVLISRTEEKEGLFFSSM
HHHHHCHHHHHHHHHHHHHCCCCCEECCCCHHHHCCCCCCCCEEEEEECCCCCCEEEEEC
IPVGWEFSSMGSIAYKLGLVAAGKASLSISLKPKNDWDICAGIALVNASGGSDLEIRSGK
CCCCCCHHHHCHHHHHHHEEEECCCEEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCC
PYKFQTVGGRGDGLVAGHTPSLIQVWESSKSHFQSGLKDWD
CEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]