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The map label for this gene is lytB [H]

Identifier: 116328163

GI number: 116328163

Start: 1729250

End: 1730248

Strand: Reverse

Name: lytB [H]

Synonym: LBL_1476

Alternate gene names: 116328163

Gene position: 1730248-1729250 (Counterclockwise)

Preceding gene: 116328164

Following gene: 116328162

Centisome position: 47.87

GC content: 41.64

Gene sequence:

>999_bases
ATGATTTTTTGGTTCTTCACTCAAAGCAAAGAATTAGAATGGCATCTGAACAGGGTTAGAATGTTAGAAAAGATCTATTT
AGCCAATCCCAGAGGATTTTGTGCCGGCGTAAAATACGCGATTTCTTACGTGGAACAGGTTCAGGCTAATTCAAAAGAAC
GTATATACGTCCGTAAAGAAATTGTACATAACCGTAGAGTTGTAGAAGATATGAAAAAAAGAGGAATTCTTTTTATCAAT
GATCTGGACGAAGCGCCTGATGGGGCCACTGTCGTTTTTTCAGCGCACGGAGTGGCTCCCTCCGTAGTAGAAGCCGCCAA
ACAAAGGGGAATGAAAATCGGAGACGCAACCTGCCCTCTCGTTACAAGAGTACATCGAAAAGCAAGAAAGATTAAAGATA
CACATCAAATCATTTACATAGGACACCAAGGACACGACGAAGCGATCGGAACCATGGGAGAAGCCGAAATGTTTCTTGTC
GAATCACCGAATGACGTAATTGCACTAAAAGATAAAATCGATCTAAACAAACCGCTTACCTATCTGATGCAAACGACTCT
TTCCATCGCCGATACGAAGAATATCGTAGATCAAATATCGAAGACATTTCCGTTCGTAGAACATCCTGTTAAAGACGATA
TCTGTTATGCGACAACGGAAAGACAGGAAGCGGTCTCTTCGATGATGAATCATATAGACGCCATGCTCGTAATCGGGGCC
GATAACAGTTCCAATTCCCTGCGCCTTTTACAACTCGCCCAAAAATCCAAACCAAATTCGTTCAAAGTGACAGGAGCTGA
CGATCTTTCCAAGGAATACATTCAAAATAATGGAATCGGAATTTTAGGGTTAACCGCGGGAGCTTCCACCCCTCAAGTTC
TCGTAGACGAAATCATTTTCAAGTTAAAAACCTTTTATCCAAATGCGGAAGTAAAATTGTTTCCCGACTCCAGGGAAGAT
TCCATGAACTTTAAACTTCCCGGAATTTTGCTCAGTTAA

Upstream 100 bases:

>100_bases
TCTTAGGCCACGTGGAAGTCCTTCCAGAGTAGATAGCTTTTGTCTTTACAAGCAGAAAAGCCGGCATCTTAAATTGGGGA
AATAAAAGCTTCGAAGATAA

Downstream 100 bases:

>100_bases
TAAAATCCGACCGCATTGCATCAATGTAATCCCTGGACGATGATTTTATGAATCATTCCCATAAATCTAAATCTTTTCTA
ATATAACATGAGTAAGTTCC

Product: penicillin tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MIFWFFTQSKELEWHLNRVRMLEKIYLANPRGFCAGVKYAISYVEQVQANSKERIYVRKEIVHNRRVVEDMKKRGILFIN
DLDEAPDGATVVFSAHGVAPSVVEAAKQRGMKIGDATCPLVTRVHRKARKIKDTHQIIYIGHQGHDEAIGTMGEAEMFLV
ESPNDVIALKDKIDLNKPLTYLMQTTLSIADTKNIVDQISKTFPFVEHPVKDDICYATTERQEAVSSMMNHIDAMLVIGA
DNSSNSLRLLQLAQKSKPNSFKVTGADDLSKEYIQNNGIGILGLTAGASTPQVLVDEIIFKLKTFYPNAEVKLFPDSRED
SMNFKLPGILLS

Sequences:

>Translated_332_residues
MIFWFFTQSKELEWHLNRVRMLEKIYLANPRGFCAGVKYAISYVEQVQANSKERIYVRKEIVHNRRVVEDMKKRGILFIN
DLDEAPDGATVVFSAHGVAPSVVEAAKQRGMKIGDATCPLVTRVHRKARKIKDTHQIIYIGHQGHDEAIGTMGEAEMFLV
ESPNDVIALKDKIDLNKPLTYLMQTTLSIADTKNIVDQISKTFPFVEHPVKDDICYATTERQEAVSSMMNHIDAMLVIGA
DNSSNSLRLLQLAQKSKPNSFKVTGADDLSKEYIQNNGIGILGLTAGASTPQVLVDEIIFKLKTFYPNAEVKLFPDSRED
SMNFKLPGILLS
>Mature_332_residues
MIFWFFTQSKELEWHLNRVRMLEKIYLANPRGFCAGVKYAISYVEQVQANSKERIYVRKEIVHNRRVVEDMKKRGILFIN
DLDEAPDGATVVFSAHGVAPSVVEAAKQRGMKIGDATCPLVTRVHRKARKIKDTHQIIYIGHQGHDEAIGTMGEAEMFLV
ESPNDVIALKDKIDLNKPLTYLMQTTLSIADTKNIVDQISKTFPFVEHPVKDDICYATTERQEAVSSMMNHIDAMLVIGA
DNSSNSLRLLQLAQKSKPNSFKVTGADDLSKEYIQNNGIGILGLTAGASTPQVLVDEIIFKLKTFYPNAEVKLFPDSRED
SMNFKLPGILLS

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=310, Percent_Identity=45.4838709677419, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 37287; Mature: 37287

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFWFFTQSKELEWHLNRVRMLEKIYLANPRGFCAGVKYAISYVEQVQANSKERIYVRKE
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHH
IVHNRRVVEDMKKRGILFINDLDEAPDGATVVFSAHGVAPSVVEAAKQRGMKIGDATCPL
HHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHH
VTRVHRKARKIKDTHQIIYIGHQGHDEAIGTMGEAEMFLVESPNDVIALKDKIDLNKPLT
HHHHHHHHHHCCCCEEEEEEECCCCCHHHCCCCCCEEEEEECCCCEEEEECCCCCCCHHH
YLMQTTLSIADTKNIVDQISKTFPFVEHPVKDDICYATTERQEAVSSMMNHIDAMLVIGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCEEEEEEC
DNSSNSLRLLQLAQKSKPNSFKVTGADDLSKEYIQNNGIGILGLTAGASTPQVLVDEIIF
CCCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
KLKTFYPNAEVKLFPDSREDSMNFKLPGILLS
HHHHCCCCCEEEECCCCCCCCCCEECCCEECC
>Mature Secondary Structure
MIFWFFTQSKELEWHLNRVRMLEKIYLANPRGFCAGVKYAISYVEQVQANSKERIYVRKE
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHH
IVHNRRVVEDMKKRGILFINDLDEAPDGATVVFSAHGVAPSVVEAAKQRGMKIGDATCPL
HHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHH
VTRVHRKARKIKDTHQIIYIGHQGHDEAIGTMGEAEMFLVESPNDVIALKDKIDLNKPLT
HHHHHHHHHHCCCCEEEEEEECCCCCHHHCCCCCCEEEEEECCCCEEEEECCCCCCCHHH
YLMQTTLSIADTKNIVDQISKTFPFVEHPVKDDICYATTERQEAVSSMMNHIDAMLVIGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCEEEEEEC
DNSSNSLRLLQLAQKSKPNSFKVTGADDLSKEYIQNNGIGILGLTAGASTPQVLVDEIIF
CCCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
KLKTFYPNAEVKLFPDSREDSMNFKLPGILLS
HHHHCCCCCEEEECCCCCCCCCCEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA